Ian J. Jackson MRC Human Genetics Unit, MRC IGMM, Western General Hospital University of Edinburgh Biography Publications Institution JoVE Articles Ian J. Jackson has not added a biography. If you are Ian J. Jackson and would like to personalize this page please email our Author Liaison for assistance. Publications A Dominant-Negative Mutation of Mouse Lmx1b Causes Glaucoma and Is Semi-lethal Via LBD1-Mediated Dimerisation PLoS Genetics. May, 2014 | Pubmed ID: 24809698 A Novel Mouse Model of Warburg Micro Syndrome Reveals Roles for RAB18 in Eye Development and Organisation of the Neuronal Cytoskeleton Disease Models & Mechanisms. Apr, 2014 | Pubmed ID: 24764192 Kdm3a Lysine Demethylase is an Hsp90 Client Required for Cytoskeletal Rearrangements During Spermatogenesis Molecular Biology of the Cell. Apr, 2014 | Pubmed ID: 24554764 A Conditional Zebrafish MITF Mutation Reveals MITF Levels Are Critical for Melanoma Promotion Vs. Regression in Vivo The Journal of Investigative Dermatology. Jan, 2014 | Pubmed ID: 23831555 Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes PLoS Genetics. Dec, 2013 | Pubmed ID: 24415959 A Trans-acting Protein Effect Causes Severe Eye Malformation in the Mp Mouse PLoS Genetics. Dec, 2013 | Pubmed ID: 24348270 How the Leopard Gets Its Spots: a Transmembrane Peptidase Specifies Feline Pigmentation Patterns Pigment Cell & Melanoma Research. Jul, 2013 | Pubmed ID: 23923821 A Comparative Phenotypic and Genomic Analysis of C57BL/6J and C57BL/6N Mouse Strains Genome Biology. Jul, 2013 | Pubmed ID: 23902802 Signatures of Diversifying Selection in European Pig Breeds PLoS Genetics. Apr, 2013 | Pubmed ID: 23637623 A CNS-specific Hypomorphic Pdgfr-beta Mutant Model of Diabetic Retinopathy Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23633653 Mutation Spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and Genotype-phenotype Correlations in Warburg Micro Syndrome and Martsolf Syndrome Human Mutation. May, 2013 | Pubmed ID: 23420520 Germline Melanocortin-1-receptor Genotype is Associated with Severity of Cutaneous Phenotype in Congenital Melanocytic Nevi: a Role for MC1R in Human Fetal Development The Journal of Investigative Dermatology. Aug, 2012 | Pubmed ID: 22572819 P-rex1는 효율적인 Melanoblast 마이그레이션 및 흑색 종 전이 필요 합니다 Nature Communications. 2011 | Pubmed ID: 22109529 Rac1 꾸미고 Pseudopod-운동 성 및 세포 주기 진행을 구동 하 여 마우스 개발 하는 동안 조직 Melanoblast 드라이브 Developmental Cell. Oct, 2011 | Pubmed ID: 21924960 마우스 게놈 변형 및 고기 및 유전자 조절에 미치는 영향 Nature. Sep, 2011 | Pubmed ID: 21921910 Differentiated Melanocyte Cell Division Occurs in Vivo and is Promoted by Mutations in Mitf Development (Cambridge, England). Aug, 2011 | Pubmed ID: 21771814 Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice PLoS Genetics. Jul, 2011 | Pubmed ID: 21750680 Human and Mouse Mutations in WDR35 Cause Short-rib Polydactyly Syndromes Due to Abnormal Ciliogenesis American Journal of Human Genetics. Apr, 2011 | Pubmed ID: 21473986 A Zebrafish Model for Nevus Regeneration Pigment Cell & Melanoma Research. Apr, 2011 | Pubmed ID: 21324102 The Opdc Missense Mutation of Pax2 Has a Milder Than Loss-of-function Phenotype Human Molecular Genetics. Jan, 2011 | Pubmed ID: 20943750 In Praise of Books Pigment Cell & Melanoma Research. Nov, 2010 | Pubmed ID: 21129162 Involvement of the Melanocortin-1 Receptor in Acute Pain and Pain of Inflammatory but Not Neuropathic Origin PloS One. 2010 | Pubmed ID: 20856883 The Physiological and Phenotypic Determinants of Human Tanning Measured As Change in Skin Colour Following a Single Dose of Ultraviolet B Radiation Experimental Dermatology. Jul, 2010 | Pubmed ID: 20648713 Human Beta-defensin 3 Has Immunosuppressive Activity in Vitro and in Vivo European Journal of Immunology. Apr, 2010 | Pubmed ID: 20104491 Ex Vivo Live Imaging of Melanoblast Migration in Embryonic Mouse Skin Pigment Cell & Melanoma Research. Apr, 2010 | Pubmed ID: 20067551 Col4a1 Mutation in Mice Causes Defects in Vascular Function and Low Blood Pressure Associated with Reduced Red Blood Cell Volume Human Molecular Genetics. Mar, 2010 | Pubmed ID: 20056676 GABAergic Amacrine 셀 및 시각적 기능 PAC1 유전자 변형 생쥐에서 감소 된다 Neuropharmacology. Jan, 2010 | Pubmed ID: 19596361 Genetic Determinants of Hair and Eye Colours in the Scottish and Danish Populations BMC Genetics. 2009 | Pubmed ID: 20042077 Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation PLoS Genetics. Nov, 2009 | Pubmed ID: 19956733 Mc1r Pathway Regulation of Zebrafish Melanosome Dispersion Zebrafish. Dec, 2008 | Pubmed ID: 19133827 Expression of the Fras1/frem Gene Family During Zebrafish Development and Fin Morphogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2008 | Pubmed ID: 18816440 Diphthamide Modification of EEF2 Requires a J-domain Protein and is Essential for Normal Development Journal of Cell Science. Oct, 2008 | Pubmed ID: 18765564 Genetics. Beta-defensin Repertoire Expands Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 18048676 Humanized MC1R Transgenic Mice Reveal Human Specific Receptor Function Human Molecular Genetics. Oct, 2007 | Pubmed ID: 17652101 Genomic Localization of a Dct-LacZ Transgene Locus: a Simple Assay for Transgene Status Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Dec, 2006 | Pubmed ID: 17083491 Cardiac Malformations and Midline Skeletal Defects in Mice Lacking Filamin A Human Molecular Genetics. Aug, 2006 | Pubmed ID: 16825286 Identifying the Genes Causing Human Diversity European Journal of Human Genetics : EJHG. Sep, 2006 | Pubmed ID: 16723996 Regulation of Pigmentation in Zebrafish Melanophores Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Jun, 2006 | Pubmed ID: 16704454 Genomic Anatomy of the Tyrp1 (brown) Deletion Complex Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16505357 Dominant Mutations of Col4a1 Result in Basement Membrane Defects Which Lead to Anterior Segment Dysgenesis and Glomerulopathy Human Molecular Genetics. Nov, 2005 | Pubmed ID: 16159887 Genotype-phenotype Correlation of Mouse Pde6b Mutations Investigative Ophthalmology & Visual Science. Sep, 2005 | Pubmed ID: 16123450 Wa5 is a Novel ENU-induced Antimorphic Allele of the Epidermal Growth Factor Receptor Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jul, 2004 | Pubmed ID: 15366372 17th International Mouse Genome Conference Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jul, 2004 | Pubmed ID: 15366370 The Extracellular Matrix Gene Frem1 is Essential for the Normal Adhesion of the Embryonic Epidermis Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15345741 The G-netics of Dark Skin Nature Genetics. Sep, 2004 | Pubmed ID: 15340429 Large-scale Analysis of Gene Structure in Rhodopsin-like GPCRs: Evidence for Widespread Loss of an Ancient Intron Gene. Aug, 2004 | Pubmed ID: 15302402 Haploinsufficiency for Phox2b in Mice Causes Dilated Pupils and Atrophy of the Ciliary Ganglion: Mechanistic Insights into Human Congenital Central Hypoventilation Syndrome Human Molecular Genetics. Jul, 2004 | Pubmed ID: 15150159 광범위 한 접선 분산 및 마우스 텍 초기 신생 하는 동안 광범위 한 세포 죽음 Developmental Biology. Mar, 2004 | Pubmed ID: 14975720 Sequence Characterization of Teleost Fish Melanocortin Receptors Annals of the New York Academy of Sciences. Jun, 2003 | Pubmed ID: 12851332 The Structure and Evolution of the Melanocortin and MCH Receptors in Fish and Mammals Genomics. Feb, 2003 | Pubmed ID: 12620396 The Promises and Problems of Linkage Analysis by Using the Current Canine Genome Map Mammalian Genome : Official Journal of the International Mammalian Genome Society. Nov, 2002 | Pubmed ID: 12461654 Neural Crest Progenitors of the Melanocyte Lineage: Coat Colour Patterns Revisited Development (Cambridge, England). Jul, 2002 | Pubmed ID: 12091305 Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability Cell. Jun, 2002 | Pubmed ID: 12086670 Presence of Visual Head Tracking Differentiates Normal Sighted from Retinal Degenerate Mice Neuroscience Letters. May, 2002 | Pubmed ID: 12023058 Dominant Role of the Niche in Melanocyte Stem-cell Fate Determination Nature. Apr, 2002 | Pubmed ID: 11976685 Novel ENU-induced Eye Mutations in the Mouse: Models for Human Eye Disease Human Molecular Genetics. Apr, 2002 | Pubmed ID: 11929848 마우스 배아의 피부와 Melanoblast 이주의 라이브 영상의 생체 문화 Richard L. Mort1, Margaret Keighren1, Leonard Hay1, Ian J. Jackson1 1MRC Human Genetics Unit, MRC IGMM, Western General Hospital, University of Edinburgh JoVE 51352 Biology
마우스 배아의 피부와 Melanoblast 이주의 라이브 영상의 생체 문화 Richard L. Mort1, Margaret Keighren1, Leonard Hay1, Ian J. Jackson1 1MRC Human Genetics Unit, MRC IGMM, Western General Hospital, University of Edinburgh JoVE 51352 Biology