Ian Parker Neurobiology and Behavior University of California, Irvine Biography Publications Institution JoVE Articles Ian Parker has not added a biography. If you are Ian Parker and would like to personalize this page please email our Author Liaison for assistance. Publications Imaging Regulatory T Cell Dynamics and CTLA4-mediated Suppression of T Cell Priming Nature Communications. 2015 | Pubmed ID: 25653051 Molecular Biophysics of Orai Store-Operated Ca(2+) Channels Biophysical Journal. Jan, 2015 | Pubmed ID: 25606672 Modulation of Elementary Calcium Release Mediates a Transition from Puffs to Waves in an IP3R Cluster Model PLoS Computational Biology. Jan, 2015 | Pubmed ID: 25569772 Fluorescence Microscopy Cold Spring Harbor Protocols. Oct, 2014 | Pubmed ID: 25275114 Single-molecule Tracking of Inositol Trisphosphate Receptors Reveals Different Motilities and Distributions Biophysical Journal. Aug, 2014 | Pubmed ID: 25140418 An Algorithm for Automated Detection, Localization and Measurement of Local Calcium Signals from Camera-based Imaging Cell Calcium. Sep, 2014 | Pubmed ID: 25047761 Termination of Calcium Puffs and Coupled Closings of Inositol Trisphosphate Receptor Channels Cell Calcium. Sep, 2014 | Pubmed ID: 25016315 Two-photon Imaging of Remyelination of Spinal Cord Axons by Engrafted Neural Precursor Cells in a Viral Model of Multiple Sclerosis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24843159 Factors Determining the Recruitment of Inositol Trisphosphate Receptor Channels During Calcium Puffs Biophysical Journal. Dec, 2013 | Pubmed ID: 24314078 Three Phases of CD8 T Cell Response in the Lung Following H1N1 Influenza Infection and Sphingosine 1 Phosphate Agonist Therapy PloS One. 2013 | Pubmed ID: 23533579 Orai1 Function is Essential for T Cell Homing to Lymph Nodes Journal of Immunology (Baltimore, Md. : 1950). Apr, 2013 | Pubmed ID: 23455504 Cytotoxicity of Intracellular Aβ42 Amyloid Oligomers Involves Ca2+ Release from the Endoplasmic Reticulum by Stimulated Production of Inositol Trisphosphate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013 | Pubmed ID: 23447594 Temperature Dependence of IP3-mediated Local and Global Ca2+ Signals Biophysical Journal. Jan, 2013 | Pubmed ID: 23442860 Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23300080 Cytosolic [Ca2+] Regulation of InsP3-evoked Puffs The Biochemical Journal. Jan, 2013 | Pubmed ID: 23035871 The Probability of Triggering Calcium Puffs is Linearly Related to the Number of Inositol Trisphosphate Receptors in a Cluster Biophysical Journal. Apr, 2012 | Pubmed ID: 22768938 Multi-scale Data-driven Modeling and Observation of Calcium Puffs Cell Calcium. Aug, 2012 | Pubmed ID: 22682010 Toll-like Receptor 4-activated B Cells Out-compete Toll-like Receptor 9-activated B Cells to Establish Peripheral Immunological Tolerance Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22511718 时间尺度的 IP (3)-诱发的经峰值摆脱经泡芙只能在细胞水平。 Biophysical Journal. Dec, 2011 | Pubmed ID: 22261051 单通道经成像涉及 Aβ1 42 淀粉样毛孔在阿尔茨海默病的病理。 The Journal of Cell Biology. Oct, 2011 | Pubmed ID: 22024165 亚基化学计量比人类的 Orai1 和 Orai3 通道的封闭与开放的国家。 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21987805 心理社会话语现在。 The British Journal of Social Psychology / the British Psychological Society. Jul, 2011 | Pubmed ID: 21790666 增强的 ER Ca2 + 存储 SERCA2b 的表达,以填补促进 IP3 诱发泡芙。 Cell Calcium. Jul, 2011 | Pubmed ID: 21616533 活动的产生和传播的 Ca2 + 内隧道膜纳米管的信号。 Biophysical Journal. Apr, 2011 | Pubmed ID: 21504718 标记: 学习使用双光子显微镜的免疫系统动力学。 Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285279 体内淋巴结成像。 Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285268 原位淋巴结成像。 Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285267 诱导的免疫反应的抗原递呈细胞 T 细胞相互作用的影像。 Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285266 领养转让和单元格标记为标记的一般做法。 Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21285265 用显微镜,不膜片钳记录完整细胞肌醇内受体的单通道活动。 The Journal of General Physiology. Aug, 2010 | Pubmed ID: 20660654 由本构 InsP3 受体 Ca2 + 转移到线粒体细胞生物能量学的基本调节。 Cell. Jul, 2010 | Pubmed ID: 20655468 超分辨本地化的单一功能 IP3R 作为读出渠道利用 Ca2 + 流量。 Biophysical Journal. Jul, 2010 | Pubmed ID: 20643061 新型突触后 Heterosynaptic 共享机制的短期的可塑性。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20592201 内质网 Ca2 + 存储区,以填补循环 ADP 核糖调制促进肌醇 (IP3)-诱发 Ca2 + 信号。 The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20538594 真皮的树突状细胞及朗格汉斯细胞 Th1 和 Th2 极化的佐剂的选择性和特定于站点的调动。 Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20404167 在阿尔茨海默病中的钙信号和淀粉样毒性。 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20212036 NK 细胞巡逻和消除捐助树突状细胞的青睐间接 Alloreactivity。 Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20139277 从数字的单镜头反光相机与 Immunoblots 的化学发光信号的购置。 Analytical Biochemistry. Feb, 2010 | Pubmed ID: 19788886 经泡芙源自肌醇内受体 Preestablished 稳定集群。 Science Signaling. 2009 | Pubmed ID: 19934435 第 16 章。双光子显微镜和多维动力学分析的单元格。 Methods in Enzymology. 2009 | Pubmed ID: 19480927 期间 Ca2 + 泡芙完好无损的哺乳动物细胞成像单一 IP3R 通道活动的量子下部的结构。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19332787 CADPR 刺激 SERCA 活动在非洲爪蟾卵母细胞中。 Cell Calcium. Mar, 2009 | Pubmed ID: 19131109 粉扑本地化网站相邻细胞质膜: 功能和空间表征的 Ca2 + 信号在 SH SY5Y 细胞利用膜 Permeant 笼的 IP3。 Cell Calcium. Jan, 2009 | Pubmed ID: 18639334 成像的效应记忆 T 细胞超敏反应和抑制期间由 Kv1.3 通道块。 Immunity. Oct, 2008 | Pubmed ID: 18835197 量子点的跟踪树突状细胞和灌注体外和体内免疫反应。 PloS One. 2008 | Pubmed ID: 18820727 元信道组成的四聚体形成的诱导伴口语二聚体二聚反应。 Nature. Nov, 2008 | Pubmed ID: 18820677 SERCA 泵活性,生理上受早老素和调节 β 淀粉样生产。 The Journal of General Physiology. Aug, 2008 | Pubmed ID: 18663130 建模 Ca2 + 对单个肌醇 1,4,5 内受体和 Ca2 + 缓冲区由其调制的反馈。 Biophysical Journal. Oct, 2008 | Pubmed ID: 18641077 SERCA 泵活性,生理上受早老素和调节 β 淀粉样生产。 The Journal of Cell Biology. Jun, 2008 | Pubmed ID: 18591429 舞蹈艺术细胞动力及相互作用动力学的淋巴器官中的双光子显微镜拍摄。 Annual Review of Immunology. 2008 | Pubmed ID: 18173372 多维决议的初等 Ca2 + 信号同时焦成像。 Cell Calcium. Apr, 2008 | Pubmed ID: 17716727 主要调控机制的配体 InsP3 受体钙释放通道模式切换。 The Journal of General Physiology. Dec, 2007 | Pubmed ID: 17998395 IA 类磷脂酰肌醇 3-激酶调节基底淋巴细胞动力的淋巴结。 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675487 妻: 倭黑猩猩被庆祝作为爱好和平的、 母系,和性解放区。它们吗? New Yorker (New York, N.Y. : 1925). Jul, 2007 | Pubmed ID: 17650578 Ca2 + 与抗原轴承在淋巴结中树突状细胞 CD4 + T 细胞在早期接触过程中的信号。 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17641025 自然杀手细胞积极巡逻外周淋巴结形成稳定的复合物,消除 MHC 不相合的目标。 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17609379 缺少 Ca2 + 反馈单和聚集 IP3 受体的动力学模型。 Biophysical Journal. Aug, 2007 | Pubmed ID: 17526578 加强兰尼碱介导的钙释放的 PS1 表示突变阿尔茨海默氏症小鼠模型。 Annals of the New York Academy of Sciences. Feb, 2007 | Pubmed ID: 17413028 基质金属蛋白酶-2 的损失扰乱了骨骼和颅面发展和减少的骨矿化,联合侵蚀会导致与缺陷的成骨细胞和破骨细胞的增长。 Human Molecular Genetics. May, 2007 | Pubmed ID: 17400654 心理分析网络空间,超越心理。 Psychoanalytic Review. Feb, 2007 | Pubmed ID: 17367277 成像单通道钙微区。 Cell Calcium. Nov-Dec, 2006 | Pubmed ID: 17067668 IP3 受体基础钙的数量和空间分布在非洲爪蟾卵母细胞中喷出。 Biophysical Journal. Dec, 2006 | Pubmed ID: 16980372 触发事件之前在非洲爪蟾卵母细胞中钙泡芙。 Biophysical Journal. Dec, 2006 | Pubmed ID: 16980363 改进毛细管渗漏和手性 S1P1 拮抗体内的淋巴细胞疏散的恢复。 Nature Chemical Biology. Aug, 2006 | Pubmed ID: 16829954 成像的淋巴细胞贩运的编排和免疫反应。 Current Opinion in Immunology. Aug, 2006 | Pubmed ID: 16765574 成像 Ca2 + 在非洲爪蟾卵母细胞中的信号。 Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16739719 Plasmalemmal Ca2 + 信号在动脉血管平滑肌: 它是小学 ! The Journal of General Physiology. Jun, 2006 | Pubmed ID: 16702356 增强兰尼碱受体招聘贡献 Ca2 + 青年、 成年、 和老年痴呆小鼠的中断。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006 | Pubmed ID: 16687509 粉扑动力学在卵母细胞中的分析: 相互依存的粉扑振幅和 Interpuff 的时间间隔。 Biophysical Journal. Jun, 2006 | Pubmed ID: 16533853 鞘氨醇 1-磷酸类型 1 受体 Agonism 到淋巴窦抑制内耳细胞迁移的髓质 T。 Nature Immunology. Dec, 2005 | Pubmed ID: 16273098 零距离接触的第一和第二种: 淋巴结 T 直流和 T B 的相互作用。 Seminars in Immunology. Dec, 2005 | Pubmed ID: 16263308 "光学膜片钳": 单通道录制的影像 Ca2 + 通过个别肌肉乙酰胆碱受体通道的通量。 The Journal of General Physiology. Sep, 2005 | Pubmed ID: 16103278 口腔吸和容忍的诱导粘膜和全身淋巴组织中的 CD4 + T 细胞行为原位表征。 The Journal of Experimental Medicine. Jun, 2005 | Pubmed ID: 15928201 抗原进行 B 细胞经过对 T 区的趋化性和能动性的窗体共轭与辅助 T 细胞。 PLoS Biology. Jun, 2005 | Pubmed ID: 15857154 光单通道记录: 成像 Ca2 + 通过单个离子通道的高时空分辨率的通量。 Journal of Biomedical Optics. Jan-Feb, 2005 | Pubmed ID: 15847568 光学单通道录制的影像 Ca2 + 通过单个离子通道的通量: 理论思考和对决议的限制。 Cell Calcium. Apr, 2005 | Pubmed ID: 15755490 钙时异常和膜破坏作为一个无处不在的神经毒性机制的可溶性淀粉样低聚物。 The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15722360 一种独立于模型的算法派生 Ca2 + 通基础本地胞浆 Ca2 + 瞬态。 Biophysical Journal. Apr, 2005 | Pubmed ID: 15681645 动态多光子成像: 从细胞到系统的动态视图。 Physiology (Bethesda, Md.). Feb, 2005 | Pubmed ID: 15653835 酶原颗粒生存期在小鼠胰腺中的两个阶段: 鬼颗粒胞内容后挥之不去。 The Journal of Physiology. Mar, 2005 | Pubmed ID: 15637100 全内反射显微镜成像单通道钙微区。 Biological Research. 2004 | Pubmed ID: 15709697 CD4 + T 细胞激活的树突状细胞在淋巴结中的单个单元格动态的影像。 The Journal of Experimental Medicine. Oct, 2004 | Pubmed ID: 15466619 全内反射荧光显微镜成像的活动和本地化的单电压门控性经渠道。 Biophysical Journal. May, 2004 | Pubmed ID: 15111438 酶原颗粒胞的特点是长时间融合孔开口和保存囊泡脂质身份。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15090649 与计算机轴向断层扫描结肠的早期经历。 American Journal of Surgery. Apr, 2004 | Pubmed ID: 15041501 在非洲爪蟾卵母细胞 Ca2 + 信号的时空阵列的 IP3 介导的 Ca2 +-结合蛋白。 The Journal of Physiology. Apr, 2004 | Pubmed ID: 14755000 表示与阿尔茨海默氏症相关的突变的 Presenilin1 敲入小鼠皮层神经元的信号水平及 IP3 结果夸大的 Ca2 + 信号和改变的细胞膜兴奋性。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14724250 T 细胞汇辑扫描是动态的树突状细胞行为和促进随机 T 细胞动力的淋巴结。 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14722354 光单通道记录: 成像 Ca2 + 通过单个 N-型电压门控通道在非洲爪蟾卵母细胞中表达的通量。 Cell Calcium. Dec, 2003 | Pubmed ID: 14572808 缓冲区动力学形状 IP3 诱发 Ca2 + 信号的时空分布。 The Journal of Physiology. Dec, 2003 | Pubmed ID: 14555715 随机查看的淋巴细胞动力及淋巴结内贩卖。 Immunological Reviews. Oct, 2003 | Pubmed ID: 12969316 体内淋巴细胞的实时图像。 Current Opinion in Immunology. Aug, 2003 | Pubmed ID: 12900266 视频率共聚焦显微镜。 Methods in Enzymology. 2003 | Pubmed ID: 12622163 光子学生物学家。 Methods in Enzymology. 2003 | Pubmed ID: 12622159 自主 T 细胞贩运检查体内与活体双光子显微镜。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12601158 由三双光子成像和 Photoreleased 磷酸肌醇 Ca2 + 鼠标皮层神经元信号转导研究。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2003 | Pubmed ID: 12574404 细胞生物学研究人类硫胺素转运蛋白-1 (hTHTR1)。胞内的贩运和针对机制的膜。 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12454006 双光子组织成像: 看到新鲜的光中的免疫系统。 Nature Reviews. Immunology. Nov, 2002 | Pubmed ID: 12415310 双光子成像在完好的淋巴组织。 Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 12405205 胞内的贩运和膜针对人类还原的叶酸载体在哺乳动物上皮细胞中的机制。 The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12087110 双光子成像的完整淋巴结淋巴细胞动力和抗原反应。 Science (New York, N.Y.). Jun, 2002 | Pubmed ID: 12016203 之间 Ca2 + 泡芙和非洲爪蟾卵母细胞中的线粒体结构和功能的关系。 American Journal of Physiology. Cell Physiology. Jun, 2002 | Pubmed ID: 11997252 AKD 存在毛细管结构下的传播的初步研究。 Journal of Colloid and Interface Science. Aug, 2001 | Pubmed ID: 11446799 成像本地CA Jeffrey T. Lock1, Kyle L. Ellefsen1, Bret Settle1, Ian Parker1,2, Ian F. Smith1 1Neurobiology and Behavior, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine Biology 细胞动力学在小鼠脊髓双光子成像 Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience 成像效应在耳朵上的记忆体T细胞诱导后收养的DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology 代骨髓衍生的双光子成像使用的小鼠树突状细胞 Melanie P. Matheu1, Debasish Sen1, Michael D Cahalan1, Ian Parker2 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 773 Biology 夹层和小鼠的外周淋巴结的双光子成像 Melanie P. Matheu1, Ian Parker2, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 265 Biology
成像本地CA Jeffrey T. Lock1, Kyle L. Ellefsen1, Bret Settle1, Ian Parker1,2, Ian F. Smith1 1Neurobiology and Behavior, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine Biology
细胞动力学在小鼠脊髓双光子成像 Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience
成像效应在耳朵上的记忆体T细胞诱导后收养的DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology
代骨髓衍生的双光子成像使用的小鼠树突状细胞 Melanie P. Matheu1, Debasish Sen1, Michael D Cahalan1, Ian Parker2 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 773 Biology
夹层和小鼠的外周淋巴结的双光子成像 Melanie P. Matheu1, Ian Parker2, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behaviour, University of California, Irvine (UCI) JoVE 265 Biology