Irwin Davidson Department of Functional Genomics and Cancer Institut de Génétique et de Biologie Moléculaire et Cellulaire Biography Publications Institution JoVE Articles Irwin Davidson has not added a biography. If you are Irwin Davidson and would like to personalize this page please email our Author Liaison for assistance. Publications MITF-high and MITF-low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra and Inter-tumoral Heterogeneity of Primary Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2017 | Pubmed ID: 28855355 Selective Elimination of Long INterspersed Element-1 Expressing Tumour Cells by Targeted Expression of the HSV-TK Suicide Gene Oncotarget. Jun, 2017 | Pubmed ID: 28415677 Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly American Journal of Human Genetics. Mar, 2017 | Pubmed ID: 28257693 TEAD Transcription Factors Are Required for Normal Primary Myoblast Differentiation in Vitro and Muscle Regeneration in Vivo PLoS Genetics. Feb, 2017 | Pubmed ID: 28178271 Macrophage Production and Activation Are Dependent on TRIM33 Oncotarget. Jan, 2017 | Pubmed ID: 27974684 TRF2 is Recruited to the Pre-initiation Complex As a Testis-specific Subunit of TFIIA/ALF to Promote Haploid Cell Gene Expression Scientific Reports. Aug, 2016 | Pubmed ID: 27576952 Essential Role of the TFIID Subunit TAF4 in Murine Embryogenesis and Embryonic Stem Cell Differentiation Nature Communications. Mar, 2016 | Pubmed ID: 27026076 Melanoma Addiction to the Long Non-coding RNA SAMMSON Nature. Mar, 2016 | Pubmed ID: 27008969 T-cell-intrinsic Tif1α/Trim24 Regulates IL-1R Expression on TH2 Cells and TH2 Cell-mediated Airway Allergy Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787865 TRIM33 Switches off Ifnb1 Gene Transcription During the Late Phase of Macrophage Activation Nature Communications. Nov, 2015 | Pubmed ID: 26592194 MITF and C-Jun Antagonism Interconnects Melanoma Dedifferentiation with Pro-inflammatory Cytokine Responsiveness and Myeloid Cell Recruitment Nature Communications. Nov, 2015 | Pubmed ID: 26530832 Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells PLoS Genetics. Oct, 2015 | Pubmed ID: 26440048 Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor PLoS Genetics. Oct, 2015 | Pubmed ID: 26427057 MITF is a Critical Regulator of the Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM1) in Malignant Melanoma Pigment Cell & Melanoma Research. Nov, 2015 | Pubmed ID: 26301891 A Brn2-Zic1 Axis Specifies the Neuronal Fate of Retinoic-acid-treated Embryonic Stem Cells Journal of Cell Science. Jul, 2015 | Pubmed ID: 25991548 Transcription Factor MITF and Remodeller BRG1 Define Chromatin Organisation at Regulatory Elements in Melanoma Cells ELife. Mar, 2015 | Pubmed ID: 25803486 Neuronal Identity Genes Regulated by Super-enhancers Are Preferentially Down-regulated in the Striatum of Huntington's Disease Mice Human Molecular Genetics. Jun, 2015 | Pubmed ID: 25784504 No Evidence for Generation of Alternatively Spliced Isoforms from the Mutated Trim24 Allele Lacking Exon 4 in Mouse Liver Journal of Hepatology. Jul, 2015 | Pubmed ID: 25701693 Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor Scientific Reports. Feb, 2015 | Pubmed ID: 25645674 TAF4, a Subunit of Transcription Factor II D, Directs Promoter Occupancy of Nuclear Receptor HNF4A During Post-natal Hepatocyte Differentiation ELife. Sep, 2014 | Pubmed ID: 25209997 TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3 PloS One. 2014 | Pubmed ID: 24498316 Sumoylation at Chromatin Governs Coordinated Repression of a Transcriptional Program Essential for Cell Growth and Proliferation Genome Research. Oct, 2013 | Pubmed ID: 23893515 MITF, the Janus Transcription Factor of Melanoma Future Oncology (London, England). Feb, 2013 | Pubmed ID: 23414473 Trim24-repressed VL30 Retrotransposons Regulate Gene Expression by Producing Noncoding RNA Nature Structural & Molecular Biology. Mar, 2013 | Pubmed ID: 23377542 Retinoic Acid Induces Sertoli Cell Paracrine Signals for Spermatogonia Differentiation but Cell Autonomously Drives Spermatocyte Meiosis Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23012458 Retinoic Acid Receptors Recognize the Mouse Genome Through Binding Elements with Diverse Spacing and Topology The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22661711 Interconversion Between Active and Inactive TATA-binding Protein Transcription Complexes in the Mouse Genome Nucleic Acids Research. Feb, 2012 | Pubmed ID: 22013162 The TIF1α-related TRIM Cofactors Couple Chromatin Modifications to Transcriptional Regulation, Signaling and Tumor Suppression Transcription. Sep-Oct, 2011 | Pubmed ID: 22231120 Front Seat and Back Seat Drivers of Melanoma Metastasis Pigment Cell & Melanoma Research. Oct, 2011 | Pubmed ID: 21910852 Transcription Cofactors TRIM24, TRIM28, and TRIM33 Associate to Form Regulatory Complexes That Suppress Murine Hepatocellular Carcinoma Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21531907 SeqMINER: an Integrated ChIP-seq Data Interpretation Platform Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21177645 Cell-specific Occupancy of an Extended Repertoire of CREM and CREB Binding Loci in Male Germ Cells BMC Genomics. Sep, 2010 | Pubmed ID: 20920259 Genome-wide Analysis of POU3F2/BRN2 Promoter Occupancy in Human Melanoma Cells Reveals Kitl As a Novel Regulated Target Gene Pigment Cell & Melanoma Research. Jun, 2010 | Pubmed ID: 20337985 Cell-specific Interaction of Retinoic Acid Receptors with Target Genes in Mouse Embryonic Fibroblasts and Embryonic Stem Cells Molecular and Cellular Biology. Jan, 2010 | Pubmed ID: 19884340 Recent Advances in Understanding the Structure and Function of General Transcription Factor TFIID Cellular and Molecular Life Sciences : CMLS. Jul, 2009 | Pubmed ID: 19308322 Specialization of the General Transcriptional Machinery in Male Germ Cells Cell Cycle (Georgetown, Tex.). Nov, 2008 | Pubmed ID: 19001848 TIPT, a Male Germ Cell-specific Partner of TRF2, is Chromatin-associated and Interacts with HP1 Cell Cycle (Georgetown, Tex.). May, 2008 | Pubmed ID: 18418073 The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-autonomous and Non-cell-autonomous Tumour Suppressor Activity in Mouse Epidermis Development (Cambridge, England). Aug, 2007 | Pubmed ID: 17626060 New Insights into TAFs As Regulators of Cell Cycle and Signaling Pathways Cell Cycle (Georgetown, Tex.). Nov, 2005 | Pubmed ID: 16205117 TAF4 Inactivation in Embryonic Fibroblasts Activates TGF Beta Signalling and Autocrine Growth The EMBO Journal. Aug, 2005 | Pubmed ID: 16015375 Proteolytic Cleavage of ALF into Alpha- and Beta-subunits That Form Homologous and Heterologous Complexes with Somatic TFIIA and TRF2 in Male Germ Cells FEBS Letters. Jun, 2005 | Pubmed ID: 15927180 Polar Nuclear Localization of H1T2, a Histone H1 Variant, Required for Spermatid Elongation and DNA Condensation During Spermiogenesis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15710904 Preparation, Isolation and Characterization of Stage-specific Spermatogenic Cells for Cellular and Molecular Analysis Nature Methods. Dec, 2004 | Pubmed ID: 16144087 Cell-specific Nucleolar Localization of TBP-related Factor 2 Molecular Biology of the Cell. Oct, 2004 | Pubmed ID: 15269281 Testis-specific Transcription Mechanisms Promoting Male Germ-cell Differentiation Reproduction (Cambridge, England). Jul, 2004 | Pubmed ID: 15232059 [TBP, a Universal Transcription Factor?] Medecine Sciences : M/S. May, 2004 | Pubmed ID: 15190478 The Genetics of TBP and TBP-related Factors Trends in Biochemical Sciences. Jul, 2003 | Pubmed ID: 12878007 The Intracellular Localisation of TAF7L, a Paralogue of Transcription Factor TFIID Subunit TAF7, is Developmentally Regulated During Male Germ-cell Differentiation Journal of Cell Science. May, 2003 | Pubmed ID: 12665565 RNA Polymerase II Transcription in Murine Cells Lacking the TATA Binding Protein Science (New York, N.Y.). Nov, 2002 | Pubmed ID: 12411709 Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-associated Factors HTAF4 (hTAF(II)135) and HTAF12 (hTAF(II)20) The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12237304 Functional Analysis of the TFIID-specific Yeast TAF4 (yTAF(II)48) Reveals an Unexpected Organization of Its Histone-fold Domain The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12237303 Distinct Mutations in Yeast TAF(II)25 Differentially Affect the Composition of TFIID and SAGA Complexes As Well As Global Gene Expression Patterns Molecular and Cellular Biology. May, 2002 | Pubmed ID: 11940675 Distinct Functions of TBP and TLF/TRF2 During Spermatogenesis: Requirement of TLF for Heterochromatic Chromocenter Formation in Haploid Round Spermatids Development (Cambridge, England). Feb, 2002 | Pubmed ID: 11861477 The TFIID Components Human TAF(II)140 and Drosophila BIP2 (TAF(II)155) Are Novel Metazoan Homologues of Yeast TAF(II)47 Containing a Histone Fold and a PHD Finger Molecular and Cellular Biology. Aug, 2001 | Pubmed ID: 11438666 Histone Folds Mediate Selective Heterodimerization of Yeast TAF(II)25 with TFIID Components YTAF(II)47 and YTAF(II)65 and with SAGA Component YSPT7 Molecular and Cellular Biology. Mar, 2001 | Pubmed ID: 11238921 The Human TFIID Components TAF(II)135 and TAF(II)20 and the Yeast SAGA Components ADA1 and TAF(II)68 Heterodimerize to Form Histone-like Pairs Molecular and Cellular Biology. Jan, 2000 | Pubmed ID: 10594036 Human TAF(II)55 Interacts with the Vitamin D(3) and Thyroid Hormone Receptors and with Derivatives of the Retinoid X Receptor That Have Altered Transactivation Properties Molecular and Cellular Biology. Aug, 1999 | Pubmed ID: 10409738 Synergistic Transcriptional Activation by TATA-binding Protein and HTAFII28 Requires Specific Amino Acids of the HTAFII28 Histone Fold Molecular and Cellular Biology. Jul, 1999 | Pubmed ID: 10373554 クロマチン免疫沈降マウス骨格筋からの改善されたプロトコル Shilpy Joshi1, Vanessa Ueberschlag-Pitiot1, Daniel Metzger1, Irwin Davidson1 1Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire JoVE 56504 Biochemistry
クロマチン免疫沈降マウス骨格筋からの改善されたプロトコル Shilpy Joshi1, Vanessa Ueberschlag-Pitiot1, Daniel Metzger1, Irwin Davidson1 1Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire JoVE 56504 Biochemistry