Javier González-Maeso Department of Psychiatry Icahn School of Medicine at Mount Sinai Biography Publications Institution JoVE Articles Javier González-Maeso has not added a biography. If you are Javier González-Maeso and would like to personalize this page please email our Author Liaison for assistance. Publications Cross-signaling in Metabotropic Glutamate 2 and Serotonin 2A Receptor Heteromers in Mammalian Cells Pflügers Archiv : European Journal of Physiology. May, 2016 | Pubmed ID: 26780666 Allosteric Signaling Through an MGlu2 and 5-HT2A Heteromeric Receptor Complex and Its Potential Contribution to Schizophrenia Science Signaling. Jan, 2016 | Pubmed ID: 26758213 Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptors in Schizophrenia Treatment Trends in Neurosciences. Aug, 2015 | Pubmed ID: 26148747 Epigenetic Signaling in Schizophrenia Cellular Signalling. Oct, 2015 | Pubmed ID: 26120009 Epigenetic Mechanisms of Serotonin Signaling ACS Chemical Neuroscience. Jul, 2015 | Pubmed ID: 25734378 G Protein-coupled Receptor Signaling to Kir Channels in Xenopus Oocytes Current Pharmaceutical Biotechnology. 2014 | Pubmed ID: 25374032 Family a GPCR Heteromers in Animal Models Frontiers in Pharmacology. 2014 | Pubmed ID: 25346690 Evaluation of 5-HT2A and MGlu2/3 Receptors in Postmortem Prefrontal Cortex of Subjects with Major Depressive Disorder: Effect of Antidepressant Treatment Neuropharmacology. Nov, 2014 | Pubmed ID: 25150943 Preclinical Models of Antipsychotic Drug Action The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Nov, 2013 | Pubmed ID: 23745738 The HIV Antiretroviral Drug Efavirenz Has LSD-like Properties Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Nov, 2013 | Pubmed ID: 23702798 G Protein-coupled Receptor Heterocomplexes in Neuropsychiatric Disorders Progress in Molecular Biology and Translational Science. 2013 | Pubmed ID: 23663970 Repressive Epigenetic Changes at the MGlu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice Molecular Pharmacology. Jun, 2013 | Pubmed ID: 23508685 Epigenetic Regulation of RAC1 Induces Synaptic Remodeling in Stress Disorders and Depression Nature Medicine. Mar, 2013 | Pubmed ID: 23416703 Animal Models of Serotonergic Psychedelics ACS Chemical Neuroscience. Jan, 2013 | Pubmed ID: 23336043 Chronic Treatment with LY341495 Decreases 5-HT(2A) Receptor Binding and Hallucinogenic Effects of LSD in Mice Neuroscience Letters. Mar, 2013 | Pubmed ID: 23333599 Prenatal Stress Induces Schizophrenia-like Alterations of Serotonin 2A and Metabotropic Glutamate 2 Receptors in the Adult Offspring: Role of Maternal Immune System The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013 | Pubmed ID: 23325246 HDAC2 As a New Target to Improve Schizophrenia Treatment Expert Review of Neurotherapeutics. Jan, 2013 | Pubmed ID: 23253383 Dysregulated 5-HT(2A) Receptor Binding in Postmortem Frontal Cortex of Schizophrenic Subjects European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. Aug, 2013 | Pubmed ID: 23176747 Persistent Effects of Chronic Clozapine on the Cellular and Behavioral Responses to LSD in Mice Psychopharmacology. Jan, 2013 | Pubmed ID: 22842765 Identification of Three Residues Essential for 5-hydroxytryptamine 2A-metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function The Journal of Biological Chemistry. Dec, 2012 | Pubmed ID: 23129762 HDAC2 Regulates Atypical Antipsychotic Responses Through the Modulation of MGlu2 Promoter Activity Nature Neuroscience. Sep, 2012 | Pubmed ID: 22864611 Reduced Levels of Serotonin 2A Receptors Underlie Resistance of Egr3-deficient Mice to Locomotor Suppression by Clozapine Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Sep, 2012 | Pubmed ID: 22692564 Décodage De La Signalisation D'un Complexe RCPG Hétéromère Révèle Un Mécanisme Unificateur D'action Des Médicaments Antipsychotiques Cell. Nov, 2011 | Pubmed ID: 22118459 Diaphonie Fonctionnelle Et Heteromerization De La Sérotonine 5-HT2A Et Récepteurs Dopaminergiques D2 Neuropharmacology. Sep, 2011 | Pubmed ID: 21645528 GPCR Oligomers in Pharmacology and Signaling Molecular Brain. 2011 | Pubmed ID: 21619615 Maternal Influenza Viral Infection Causes Schizophrenia-like Alterations of 5-HT₂A and MGlu₂ Receptors in the Adult Offspring The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2011 | Pubmed ID: 21289196 Métabotropique Du Glutamate MGlu2 Récepteur Est Nécessaire Pour Les Effets Pharmacologiques Et Comportementaux Induits Par Hallucinogènes Agonistes Des Récepteurs 5-HT2A Neuroscience Letters. Apr, 2011 | Pubmed ID: 21276828 α₂-Adrenoceptor Functionality in Postmortem Frontal Cortex of Depressed Suicide Victims Biological Psychiatry. Nov, 2010 | Pubmed ID: 20864091 Heteromerization Du G Récepteurs Couplés Aux Protéines: Pertinence Des Troubles Neurologiques Et Neurotherapeutics CNS & Neurological Disorders Drug Targets. Nov, 2010 | Pubmed ID: 20632964 Anxious Interactions Nature Neuroscience. May, 2010 | Pubmed ID: 20421895 Groupe II Récepteurs Métabotropiques Du Glutamate Et De La Schizophrénie Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19707855 Agoniste-traite Et Hallucinogènes Current Medicinal Chemistry. 2009 | Pubmed ID: 19275609 Psychédéliques Et De La Schizophrénie Trends in Neurosciences. Apr, 2009 | Pubmed ID: 19269047 Paire De Récepteur Pour La Schizophrénie Pediatric Research. Jul, 2008 | Pubmed ID: 18574404 Identification D'un Complexe Récepteur De La Sérotonine / Glutamate Impliqué Dans La Psychose Nature. Mar, 2008 | Pubmed ID: 18297054 Hallucinogènes Recruter Spécifiques Corticaux De 5-HT (2A) Voies De Signalisation Médiée Par Le Récepteur D'affecter Le Comportement Neuron. Feb, 2007 | Pubmed ID: 17270739 Heterotrimeric G Proteins: Insights into the Neurobiology of Mood Disorders Current Neuropharmacology. Apr, 2006 | Pubmed ID: 18615130 Médiatise P53 Mort Cellulaire Dans Les Cellules Dopaminergiques Nontranscriptional En Réponse à L'inhibition Du Protéasome The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17060322 Corticale Signalisation Du Récepteur 5-HT2A Modulation De L'anxiété-comme Des Comportements Chez Les Souris Science (New York, N.Y.). Jul, 2006 | Pubmed ID: 16873667 Méthode Pour La Détection Des ARNm Cellulaires Multiplex Utilisation Quantum Dot Hybridation Fluorescente in Situ Nucleic Acids Research. 2005 | Pubmed ID: 16224100 Epsilon-sarcoglycane Immunoréactivité Et Expression De L'ARNm Dans Le Cerveau De Souris The Journal of Comparative Neurology. Jan, 2005 | Pubmed ID: 15612018 Agonist-induced Desensitization and Endocytosis of Heterodimeric GABAB Receptors in CHO-K1 Cells European Journal of Pharmacology. Nov, 2003 | Pubmed ID: 14637170 Les Empreintes Digitales Du Transcriptome Distinguer Hallucinogènes Et Nonhallucinogenic La 5-hydroxytryptamine 2A Effets Agoniste Du Récepteur De La Souris Cortex Somatosensoriel The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14523084 Validé L'approche Génomique Pour L'étude Des Gènes Différentiellement Exprimés Dans Les Tissus Complexes Neurochemical Research. Oct, 2002 | Pubmed ID: 12462402 Quantitative Stoichiometry of G-proteins Activated by Mu-opioid Receptors in Postmortem Human Brain European Journal of Pharmacology. Sep, 2002 | Pubmed ID: 12323382 Effects of Age, Postmortem Delay and Storage Time on Receptor-mediated Activation of G-proteins in Human Brain Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2002 | Pubmed ID: 11927171 Distribution of Prolyl Endopeptidase Activities in Rat and Human Brain Neurochemistry International. Apr, 2002 | Pubmed ID: 11792464 HSV-Mediated Expression du transgène de chimériques Constructs pour étudier la fonction Behavioral des GPCR hétéromères chez la souris Terrell Holloway1, Jose L. Moreno1, Javier González-Maeso1,2,3,4 1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 2Department of Neurology, Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics, Virginia Commonwealth University Medical School JoVE 53717 Neuroscience
HSV-Mediated Expression du transgène de chimériques Constructs pour étudier la fonction Behavioral des GPCR hétéromères chez la souris Terrell Holloway1, Jose L. Moreno1, Javier González-Maeso1,2,3,4 1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 2Department of Neurology, Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics, Virginia Commonwealth University Medical School JoVE 53717 Neuroscience