Jens Juul Holst Department of Biomedical Sciences, Faculty of Health and Medical Sciences University of Copenhagen Biography Publications Institution JoVE Articles Jens Juul Holst has not added a biography. If you are Jens Juul Holst and would like to personalize this page please email our Author Liaison for assistance. Publications Unravelling Effects of Rosemary ( L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet Metabolites. Aug, 2023 | Pubmed ID: 37755254 Primary Weight Loss Failure After Roux-en-Y Gastric Bypass is Characterized by Impaired Gut-hormone Mediated Regulation of Food Intake International Journal of Obesity (2005). Aug, 2023 | Pubmed ID: 37653071 Post-prandial Secretion of Glucagon-like Peptide-2 (GLP-2) After Carbohydrate-, Fat- or Protein Enriched Meals in Healthy Subjects Peptides. Nov, 2023 | Pubmed ID: 37640265 Effects of Aerobic Training and Semaglutide Treatment on Pancreatic β-cell Secretory Function in Patients with Type 2 Diabetes The Journal of Clinical Endocrinology and Metabolism. Jun, 2023 | Pubmed ID: 37265222 Increased Meal-induced Neurotensin Response Predicts Successful Maintenance of Weight Loss - Data from a Randomized Controlled Trial Metabolism: Clinical and Experimental. Jun, 2023 | Pubmed ID: 36933790 Standard Procedures for Blood Withdrawal in Conscious Male Rats Induce Stress and Profoundly Affect Glucose Tolerance and Secretion of Glucoregulatory Hormones Molecular Metabolism. Mar, 2023 | Pubmed ID: 36739969 Biased GLP-2 Agonist with Strong G Protein-coupling but Impaired Arrestin Recruitment and Receptor Desensitization Enhances Intestinal Growth in Mice British Journal of Pharmacology. Jul, 2023 | Pubmed ID: 36683195 Glucagon 100 Years. Important, but Still Enigmatic Peptides. Mar, 2023 | Pubmed ID: 36626940 Endogenous Incretin Levels and Risk of First Incident Cancer: a Prospective Cohort Study Scientific Reports. Jan, 2023 | Pubmed ID: 36611045 Gastrointestinal Hormones and Appetite Ratings After Weight Loss Induced by Diet or Bariatric Surgery Obesity (Silver Spring, Md.). Feb, 2023 | Pubmed ID: 36536482 Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins The Journal of Clinical Endocrinology and Metabolism. Jan, 2023 | Pubmed ID: 36181459 Incretin-based Therapy of Metabolic Disease Danish Medical Journal. Dec, 2022 | Pubmed ID: 36629298 Evaluation of Commercially Available Glucagon Receptor Antibodies and Glucagon Receptor Expression Communications Biology. Nov, 2022 | Pubmed ID: 36418521 Prolonged Lipopolysaccharide-induced Illness Elevates Glucagon-like Peptide-1 and Suppresses Peptide YY: A Human-randomized Cross-over Trial Physiological Reports. Sep, 2022 | Pubmed ID: 36117310 GIP Affects Hepatic Fat and Brown Adipose Tissue Thermogenesis but Not White Adipose Tissue Transcriptome in Type 1 Diabetes The Journal of Clinical Endocrinology and Metabolism. Nov, 2022 | Pubmed ID: 36111559 Exenatide Once Weekly for Alcohol Use Disorder Investigated in a Randomized, Placebo-controlled Clinical Trial JCI Insight. Oct, 2022 | Pubmed ID: 36066977 Glucagon and Other Proglucagon-derived Peptides in the Pathogenesis of Obesity Frontiers in Nutrition. 2022 | Pubmed ID: 35990325 Reply - Letter to the Editor - On Carbohydrate Restriction and Health-related Quality of Life and Cognition in Type 2 Diabetes Clinical Nutrition (Edinburgh, Scotland). Sep, 2022 | Pubmed ID: 35981924 Exploratory Analysis of Eating- and Physical Activity-related Outcomes from a Randomized Controlled Trial for Weight Loss Maintenance with Exercise and Liraglutide Single or Combination Treatment Nature Communications. Aug, 2022 | Pubmed ID: 35970829 Investigating the Roles of Hyperglycaemia, Hyperinsulinaemia and Elevated Free Fatty Acids in Cardiac Function in Patients with Type 2 Diabetes Via Treatment with Insulin Compared with Empagliflozin: Protocol for the HyperCarD2 Randomised, Crossover Trial BMJ Open. Aug, 2022 | Pubmed ID: 35953245 The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection Frontiers in Endocrinology. 2022 | Pubmed ID: 35846282 Glucose-dependent Insulinotropic Polypeptide Receptor Antagonist Treatment Causes a Reduction in Weight Gain in Ovariectomised High Fat Diet-fed Mice British Journal of Pharmacology. Sep, 2022 | Pubmed ID: 35710141 Weight-loss Induced by Carbohydrate Restriction Does Not Negatively Affect Health-related Quality of Life and Cognition in People with Type 2 Diabetes: A Randomised Controlled Trial Clinical Nutrition (Edinburgh, Scotland). Jul, 2022 | Pubmed ID: 35679680 Glucagon-like Peptide-1 Effect on β-cell Function Varies According to Diabetes Remission Status After Roux-en-Y Gastric Bypass Diabetes, Obesity & Metabolism. Nov, 2022 | Pubmed ID: 35676799 Discovery of the GI Effects of GLP-1: An Historical Perspective Digestive Diseases and Sciences. Jul, 2022 | Pubmed ID: 35635627 The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion Metabolites. May, 2022 | Pubmed ID: 35629924 Impact of Polymorphism in the β2-Receptor Gene on Metabolic Responses to Repeated Hypoglycemia in Healthy Humans The Journal of Clinical Endocrinology and Metabolism. Jul, 2022 | Pubmed ID: 35552407 N-terminal Alterations Turn the Gut Hormone GLP-2 into an Antagonist with Gradual Loss of GLP-2 Receptor Selectivity Towards More GLP-1 Receptor Interaction British Journal of Pharmacology. Sep, 2022 | Pubmed ID: 35523760 Early Effects of Roux-en-Y Gastric Bypass on Dietary Fatty Acid Absorption and Metabolism in People with Obesity and Normal Glucose Tolerance International Journal of Obesity (2005). Jul, 2022 | Pubmed ID: 35459799 Extreme Duration Exercise Affects Old and Younger Men Differently Acta Physiologica (Oxford, England). Jul, 2022 | Pubmed ID: 35347845 Opposing Roles of the Entero-pancreatic Hormone Urocortin-3 in Glucose Metabolism in Rats Diabetologia. Jun, 2022 | Pubmed ID: 35325259 GLP-1 - Incretin and Pleiotropic Hormone with Pharmacotherapy Potential. Increasing Secretion of Endogenous GLP-1 for Diabetes and Obesity Therapy Current Opinion in Pharmacology. Apr, 2022 | Pubmed ID: 35231672 GIP and GLP-2 Together Improve Bone Turnover in Humans Supporting GIPR-GLP-2R Co-agonists As Future Osteoporosis Treatment Pharmacological Research. Feb, 2022 | Pubmed ID: 34995796 Peptides in the Regulation of Glucagon Secretion Peptides. Feb, 2022 | Pubmed ID: 34748791 The Incretin/glucagon System As a Target for Pharmacotherapy of Obesity Obesity Reviews : an Official Journal of the International Association for the Study of Obesity. Feb, 2022 | Pubmed ID: 34713962 Colonic Lactulose Fermentation Has No Impact on Glucagon-like Peptide-1 and Peptide-YY Secretion in Healthy Young Men The Journal of Clinical Endocrinology and Metabolism. Jan, 2022 | Pubmed ID: 34508600 Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg) The Journal of Clinical Endocrinology and Metabolism. Jan, 2022 | Pubmed ID: 34463768 Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A Post Hoc Analysis of the U-TURN Trial Medicine and Science in Sports and Exercise. Jan, 2022 | Pubmed ID: 34431828 Actions of Glucagon-like Peptide-1 Receptor Ligands in the Gut British Journal of Pharmacology. Feb, 2022 | Pubmed ID: 34235727 Effect of 6 Weeks of Very Low-volume High-intensity Interval Training on Oral Glucose-stimulated Incretin Hormone Response European Journal of Sport Science. Mar, 2022 | Pubmed ID: 33461430 Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation Frontiers in Immunology. 2021 | Pubmed ID: 34956226 Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture Diabetes. Nov, 2021 | Pubmed ID: 34711671 The Liver-alpha-cell Axis After a Mixed Meal and During Weight Loss in Type 2 Diabetes Endocrine Connections. Sep, 2021 | Pubmed ID: 34382579 Plasma GDF15 Levels Are Similar Between Subjects After Bariatric Surgery and Matched Controls and Are Unaffected by Meals American Journal of Physiology. Endocrinology and Metabolism. Oct, 2021 | Pubmed ID: 34370594 The Effect of Melatonin on Incretin Hormones: Results From Experimental and Randomized Clinical Studies The Journal of Clinical Endocrinology and Metabolism. Nov, 2021 | Pubmed ID: 34265066 Subcutaneous GIP and GLP-2 Inhibit Nightly Bone Resorption in Postmenopausal Women: A Preliminary Study Bone. Nov, 2021 | Pubmed ID: 34153529 Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors Frontiers in Endocrinology. 2021 | Pubmed ID: 34108943 What Combines Best with GLP-1 for Obesity Treatment: GIP Receptor Agonists or Antagonists? Cell Reports. Medicine. May, 2021 | Pubmed ID: 34095885 Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, in Patients with Short Bowel Syndrome and Colon in Continuity: an Open-label Pilot Study BMJ Open Gastroenterology. May, 2021 | Pubmed ID: 33975891 GLP-1 and Intestinal Diseases Biomedicines. Apr, 2021 | Pubmed ID: 33916501 Exploring the GLP-1-GLP-1R Axis in Porcine Pancreas and Gastrointestinal Tract in Vivo by Ex Vivo Autoradiography BMJ Open Diabetes Research & Care. Apr, 2021 | Pubmed ID: 33903116 The Antiresorptive Effect of GIP, But Not GLP-2, Is Preserved in Patients With Hypoparathyroidism-A Randomized Crossover Study Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2021 | Pubmed ID: 33852173 The Role of Incretins on Insulin Function and Glucose Homeostasis Endocrinology. Jul, 2021 | Pubmed ID: 33782700 Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice Frontiers in Endocrinology. 2021 | Pubmed ID: 33716991 In Patients with Controlled Acromegaly, Indices of Glucose Homeostasis Correlate with IGF-1 Levels Rather Than with Type of Treatment Clinical Endocrinology. Jul, 2021 | Pubmed ID: 33715210 β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion During Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial The Journal of Nutrition. Jun, 2021 | Pubmed ID: 33693737 GIP Receptor Deletion in Mice Confers Resistance to High-fat Diet-induced Obesity Via Alterations in Energy Expenditure and Adipose Tissue Lipid Metabolism American Journal of Physiology. Endocrinology and Metabolism. Apr, 2021 | Pubmed ID: 33645252 Amino Acids Differ in Their Capacity to Stimulate GLP-1 Release from the Perfused Rat Small Intestine and Stimulate Secretion by Different Sensing Mechanisms American Journal of Physiology. Endocrinology and Metabolism. May, 2021 | Pubmed ID: 33645250 What is Diabetes Remission? Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders. Mar, 2021 | Pubmed ID: 33609265 Genome-wide Association Study of Circulating Levels of Glucagon During an Oral Glucose Tolerance Test BMC Medical Genomics. Jan, 2021 | Pubmed ID: 33407418 The Effect of Preceding Glucose Decline Rate on Low-dose Glucagon Efficacy in Individuals with Type 1 Diabetes: A Randomized Crossover Trial Diabetes, Obesity & Metabolism. Apr, 2021 | Pubmed ID: 33336888 Pharmacokinetics of Exogenous GIP(1-42) in C57Bl/6 Mice; Extremely Rapid Degradation but Marked Variation Between Available Assays Peptides. Feb, 2021 | Pubmed ID: 33245951 Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness Diabetes Care. Jan, 2021 | Pubmed ID: 33208488 Paracrine Regulation of Somatostatin Secretion by Insulin and Glucagon in Mouse Pancreatic Islets Diabetologia. Jan, 2021 | Pubmed ID: 33043402 Counterregulatory Responses to Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. Jan, 2021 | Pubmed ID: 33039341 Effects of Whey Protein and Dietary Fiber Intake on Insulin Sensitivity, Body Composition, Energy Expenditure, Blood Pressure, and Appetite in Subjects with Abdominal Obesity European Journal of Clinical Nutrition. Apr, 2021 | Pubmed ID: 32948867 Preserved Postprandial Suppression of Bone Turnover Markers, Despite Increased Fasting Levels, in Postmenopausal Women Bone. Feb, 2021 | Pubmed ID: 32853851 Incretin Hormones and Type 2 Diabetes-Mechanistic Insights and Therapeutic Approaches Biology. Dec, 2020 | Pubmed ID: 33339298 Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis Hepatology Communications. Nov, 2020 | Pubmed ID: 33163832 Glucagon Acutely Regulates Hepatic Amino Acid Catabolism and the Effect May Be Disturbed by Steatosis Molecular Metabolism. Dec, 2020 | Pubmed ID: 32937194 Oral D/L-3-Hydroxybutyrate Stimulates Cholecystokinin and Insulin Secretion and Slows Gastric Emptying in Healthy Males The Journal of Clinical Endocrinology and Metabolism. Oct, 2020 | Pubmed ID: 32717058 Secretion of Parathyroid Hormone May Be Coupled to Insulin Secretion in Humans Endocrine Connections. Jul, 2020 | Pubmed ID: 32698134 GIP As a Therapeutic Target in Diabetes and Obesity: Insight From Incretin Co-agonists The Journal of Clinical Endocrinology and Metabolism. Aug, 2020 | Pubmed ID: 32459834 Effects of a Highly Controlled Carbohydrate-reduced High-protein Diet on Markers of Oxidatively Generated Nucleic Acid Modifications and Inflammation in Weight Stable Participants with Type 2 Diabetes; a Randomized Controlled Trial Scandinavian Journal of Clinical and Laboratory Investigation. Sep, 2020 | Pubmed ID: 32374188 Predictors of Weight Loss After Bariatric Surgery-a Cross-disciplinary Approach Combining Physiological, Social, and Psychological Measures International Journal of Obesity (2005). Nov, 2020 | Pubmed ID: 32327722 Pharmacological Activation of TGR5 Promotes Intestinal Growth Via a GLP-2-dependent Pathway in Mice American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2020 | Pubmed ID: 32308039 Changes in the Homeostatic Appetite System After Weight Loss Reflect a Normalization Toward a Lower Body Weight The Journal of Clinical Endocrinology and Metabolism. Jul, 2020 | Pubmed ID: 32301981 Proglucagon Peptide Secretion Profiles in Type 2 Diabetes Before and After Bariatric Surgery: 1-year Prospective Study BMJ Open Diabetes Research & Care. Mar, 2020 | Pubmed ID: 32209584 Gain-of-function Mutation in the Voltage-gated Potassium Channel Gene KCNQ1 and Glucose-stimulated Hypoinsulinemia - Case Report BMC Endocrine Disorders. Mar, 2020 | Pubmed ID: 32164657 Nutrient Restriction Has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs The Journal of Nutrition. May, 2020 | Pubmed ID: 32069355 Oxyntomodulin and Glicentin May Predict the Effect of Bariatric Surgery on Food Preferences and Weight Loss The Journal of Clinical Endocrinology and Metabolism. Apr, 2020 | Pubmed ID: 32016415 Secretin Release After Roux-en-Y Gastric Bypass Reveals a Population of Glucose-sensitive S Cells in Distal Small Intestine International Journal of Obesity (2005). Sep, 2020 | Pubmed ID: 32015474 Glucagon-Like Peptide 1 and Atrial Natriuretic Peptide in a Female Mouse Model of Obstructive Pulmonary Disease Journal of the Endocrine Society. Jan, 2020 | Pubmed ID: 32010874 Consumption of Nutrients and Insulin Resistance Suppress Markers of Bone Turnover in Subjects with Abdominal Obesity Bone. Apr, 2020 | Pubmed ID: 31954199 Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass Obesity Surgery. Mar, 2020 | Pubmed ID: 31907828 Recent Advances of GIP and Future Horizons Peptides. Mar, 2020 | Pubmed ID: 31838219 Incretin Therapy for Diabetes Mellitus Type 2 Current Opinion in Endocrinology, Diabetes, and Obesity. Feb, 2020 | Pubmed ID: 31815785 Correction To: Effects of Glucagon-like Peptide 1 Analogs on Alcohol Intake in Alcohol-preferring Vervet Monkeys Psychopharmacology. Jan, 2020 | Pubmed ID: 31768561 A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals Obesity Surgery. Apr, 2020 | Pubmed ID: 31709494 Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1 The Journal of Clinical Endocrinology and Metabolism. Jan, 2020 | Pubmed ID: 31608930 A Pilot Study Showing Acute Inhibitory Effect of GLP-1 on the Bone Resorption Marker CTX in Humans JBMR Plus. Oct, 2019 | Pubmed ID: 31687645 Protocol for a Randomised Controlled Trial of the Combined Effects of the GLP-1 Receptor Agonist Liraglutide and Exercise on Maintenance of Weight Loss and Health After a Very Low-calorie Diet BMJ Open. Nov, 2019 | Pubmed ID: 31678947 Methods and Guidelines for Measurement of Glucagon in Plasma International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31671667 Effects of Exercise Training and IL-6 Receptor Blockade on Gastric Emptying and GLP-1 Secretion in Obese Humans: Secondary Analyses From a Double Blind Randomized Clinical Trial Frontiers in Physiology. 2019 | Pubmed ID: 31636570 Effects of a High-Protein/Moderate-Carbohydrate Diet on Appetite, Gut Peptides, and Endocannabinoids-A Preview Study Nutrients. Sep, 2019 | Pubmed ID: 31546629 Short-chain Fatty Acids and Regulation of Pancreatic Endocrine Secretion in Mice Islets. 2019 | Pubmed ID: 31469342 Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats Frontiers in Endocrinology. 2019 | Pubmed ID: 31447774 The Imprinted Gene Delta Like Non-canonical Notch Ligand 1 (Dlk1) Associates with Obesity and Triggers Insulin Resistance Through Inhibition of Skeletal Muscle Glucose Uptake EBioMedicine. Aug, 2019 | Pubmed ID: 31383551 Pros and Cons of Roux En-Y Gastric Bypass Surgery in Obese Patients with Type 2 Diabetes Expert Review of Endocrinology & Metabolism. Jul, 2019 | Pubmed ID: 31215828 The Diurnal Variation of Bone Formation is Attenuated in Adult Patients with Type 2 Diabetes European Journal of Endocrinology. Sep, 2019 | Pubmed ID: 31189129 Which to Choose, an Oral or an Injectable Glucagon-like Peptide-1 Receptor Agonist? Lancet (London, England). Jul, 2019 | Pubmed ID: 31186119 Liraglutide Improves the Beta-cell Function Without Increasing Insulin Secretion During a Mixed Meal in Patients, Who Exhibit Well-controlled Type 2 Diabetes and Coronary Artery Disease Diabetology & Metabolic Syndrome. 2019 | Pubmed ID: 31164926 Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass and the Effects of Acarbose, Sitagliptin, Verapamil, Liraglutide and Pasireotide Diabetes, Obesity & Metabolism. Sep, 2019 | Pubmed ID: 31144430 From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy Frontiers in Endocrinology. 2019 | Pubmed ID: 31080438 GIP-induced Vasodilation in Human Adipose Tissue Involves Capillary Recruitment Endocrine Connections. Jun, 2019 | Pubmed ID: 31063975 Postprandial Levels of GLP-1, GIP and Glucagon After 2 Years of Weight Loss with a Paleolithic Diet: a Randomised Controlled Trial in Healthy Obese Women European Journal of Endocrinology. Jun, 2019 | Pubmed ID: 31042670 Liraglutide-Induced Weight Loss May Be Affected by Autonomic Regulation in Type 1 Diabetes Frontiers in Endocrinology. 2019 | Pubmed ID: 31031712 The Incretin System in Healthy Humans: The Role of GIP and GLP-1 Metabolism: Clinical and Experimental. Jul, 2019 | Pubmed ID: 31029770 Peptone-mediated Glucagon-like Peptide-1 Secretion Depends on Intestinal Absorption and Activation of Basolaterally Located Calcium-Sensing Receptors Physiological Reports. Apr, 2019 | Pubmed ID: 31020803 Long-acting Glucagon-like Peptide-1 Receptor Agonist-status December 2018 Annals of Translational Medicine. Mar, 2019 | Pubmed ID: 31019933 Plasma FGF-19 Levels Are Increased in Patients with Post-Bariatric Hypoglycemia Obesity Surgery. Jul, 2019 | Pubmed ID: 30976983 No Direct Effect of SGLT2 Activity on Glucagon Secretion Diabetologia. Jun, 2019 | Pubmed ID: 30903205 Gut Hormones and Their Effect on Bone Metabolism. Potential Drug Therapies in Future Osteoporosis Treatment Frontiers in Endocrinology. 2019 | Pubmed ID: 30863364 Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men Without Diabetes The Journal of Clinical Endocrinology and Metabolism. Jul, 2019 | Pubmed ID: 30848791 Augmented GLP-1 Secretion As Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion The Journal of Clinical Endocrinology and Metabolism. Aug, 2019 | Pubmed ID: 30844053 Effect of Liraglutide on Body Weight and Microvascular Function in Non-diabetic Overweight Women with Coronary Microvascular Dysfunction International Journal of Cardiology. May, 2019 | Pubmed ID: 30773266 Bile Acids Drive Colonic Secretion of Glucagon-like-peptide 1 and Peptide-YY in Rodents American Journal of Physiology. Gastrointestinal and Liver Physiology. Feb, 2019 | Pubmed ID: 30767682 Postprandial Nutrient Handling and Gastrointestinal Secretion of Hormones After Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy Gastroenterology. Feb, 2019 | Pubmed ID: 30742833 The Effect of DPP-4-protected GLP-1 (7-36) on Coronary Microvascular Function in Obese Adults International Journal of Cardiology. Heart & Vasculature. Mar, 2019 | Pubmed ID: 30740510 Glucagon-Like Peptide-1 Is a Marker of Systemic Inflammation in Patients Treated with High-Dose Chemotherapy and Autologous Stem Cell Transplantation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jun, 2019 | Pubmed ID: 30731250 Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients The Journal of Clinical Endocrinology and Metabolism. Feb, 2019 | Pubmed ID: 30726969 Effects of Active Commuting and Leisure-time Exercise on Appetite in Individuals with Overweight and Obesity Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2019 | Pubmed ID: 30605397 Pre-meal and Postprandial Lipaemia in Subjects with the Metabolic Syndrome: Effects of Timing and Protein Quality (randomised Crossover Trial) The British Journal of Nutrition. Feb, 2019 | Pubmed ID: 30599817 Effects of Glucagon-like Peptide 1 Analogs on Alcohol Intake in Alcohol-preferring Vervet Monkeys Psychopharmacology. Feb, 2019 | Pubmed ID: 30382353 WITHDRAWN: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries The Journal of Clinical Endocrinology and Metabolism. Jan, 2019 | Pubmed ID: 29750414 A Pre-meal of Whey Proteins Induces Differential Effects on Glucose and Lipid Metabolism in Subjects with the Metabolic Syndrome: a Randomised Cross-over Trial European Journal of Nutrition. Mar, 2019 | Pubmed ID: 29626232 Whole Grain-rich Diet Reduces Body Weight and Systemic Low-grade Inflammation Without Inducing Major Changes of the Gut Microbiome: a Randomised Cross-over Trial Gut. Jan, 2019 | Pubmed ID: 29097438 Neuromedin U Does Not Act As a Decretin in Rats Cell Metabolism. Nov, 2018 | Pubmed ID: 30449683 A Low-gluten Diet Induces Changes in the Intestinal Microbiome of Healthy Danish Adults Nature Communications. Nov, 2018 | Pubmed ID: 30425247 Insulin Secretion Depends on Intra-islet Glucagon Signaling Cell Reports. Oct, 2018 | Pubmed ID: 30380405 Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations-Role of Carbohydrate and Energy Availability Diabetes. Nov, 2018 | Pubmed ID: 30348819 Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review" The Journal of Clinical Endocrinology and Metabolism. Dec, 2018 | Pubmed ID: 30239764 Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects Nutrients. Sep, 2018 | Pubmed ID: 30213037 Patient Profiling for Success After Weight Loss Surgery (GO Bypass Study): An Interdisciplinary Study Protocol Contemporary Clinical Trials Communications. Jun, 2018 | Pubmed ID: 30023446 Non-insulin Pharmacological Therapies for Treating Type 1 Diabetes Expert Opinion on Pharmacotherapy. Jun, 2018 | Pubmed ID: 29991320 Endogenous Glucagon-like Peptide- 1 and 2 Are Essential for Regeneration After Acute Intestinal Injury in Mice PloS One. 2018 | Pubmed ID: 29864142 Mechanisms in Bariatric Surgery: Gut Hormones, Diabetes Resolution, and Weight Loss Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. 05, 2018 | Pubmed ID: 29776493 Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control Cell Metabolism. Jun, 2018 | Pubmed ID: 29731416 Erratum to Semaglutide Seems to Be More Effective the Other GLP-1Ras Annals of Translational Medicine. Feb, 2018 | Pubmed ID: 29611550 Hemodynamic Effects of Glucagon: A Literature Review The Journal of Clinical Endocrinology and Metabolism. May, 2018 | Pubmed ID: 29546411 Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients: No Significant Differences in Biomarkers, Including Plasma Phe Levels Journal of Nutrition and Metabolism. 2018 | Pubmed ID: 29511574 The Impact of Short-chain Fatty Acids on GLP-1 and PYY Secretion from the Isolated Perfused Rat Colon American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2018 | Pubmed ID: 29494208 Glucose-dependent Insulinotropic Polypeptide (GIP) Receptor Antagonists As Anti-diabetic Agents Peptides. Feb, 2018 | Pubmed ID: 29412817 Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and Without Type 2 Diabetes: A Randomized, Crossover Trial Nutrients. Jan, 2018 | Pubmed ID: 29370144 Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study Diabetes Care. Apr, 2018 | Pubmed ID: 29358493 Comparing Olive Oil and C4-dietary Oil, a Prodrug for the GPR119 Agonist, 2-oleoyl Glycerol, Less Energy Intake of the Latter is Needed to Stimulate Incretin Hormone Secretion in Overweight Subjects with Type 2 Diabetes Nutrition & Diabetes. 01, 2018 | Pubmed ID: 29330461 Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans The Journal of Clinical Endocrinology and Metabolism. Feb, 2018 | Pubmed ID: 29177486 Effects of a Diet Rich in Arabinoxylan and Resistant Starch Compared with a Diet Rich in Refined Carbohydrates on Postprandial Metabolism and Features of the Metabolic Syndrome European Journal of Nutrition. Mar, 2018 | Pubmed ID: 28070639 Effect of Liraglutide Treatment on Jejunostomy Output in Patients With Short Bowel Syndrome: An Open-Label Pilot Study JPEN. Journal of Parenteral and Enteral Nutrition. Jan, 2018 | Pubmed ID: 27875281 Semaglutide Seems to Be More Effective the Other GLP-1Ras Annals of Translational Medicine. Dec, 2017 | Pubmed ID: 29299466 Glucagon-like Peptide-1 Acutely Affects Renal Blood Flow and Urinary Flow Rate in Spontaneously Hypertensive Rats Despite Significantly Reduced Renal Expression of GLP-1 Receptors Physiological Reports. Dec, 2017 | Pubmed ID: 29233907 Instrumentalization of Eating Improves Weight Loss Maintenance in Obesity Obesity Facts. 2017 | Pubmed ID: 29207396 Discovery, Characterization, and Clinical Development of the Glucagon-like Peptides The Journal of Clinical Investigation. Dec, 2017 | Pubmed ID: 29202475 Genetic Determinants of Circulating GIP and GLP-1 Concentrations JCI Insight. Nov, 2017 | Pubmed ID: 29093273 DPP4 Gene Variation Affects GLP-1 Secretion, Insulin Secretion, and Glucose Tolerance in Humans with High Body Adiposity PloS One. 2017 | Pubmed ID: 28750074 The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor Diabetes. Sep, 2017 | Pubmed ID: 28667118 Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes Journal of Diabetes Science and Technology. Nov, 2017 | Pubmed ID: 28654314 The Gut: A Key to the Pathogenesis of Type 2 Diabetes? Metabolic Syndrome and Related Disorders. Aug, 2017 | Pubmed ID: 28605280 Effect of Oral Contraceptives And/or Metformin on GLP-1 Secretion and Reactive Hypoglycaemia in Polycystic Ovary Syndrome Endocrine Connections. May, 2017 | Pubmed ID: 28432082 Short-term Effects of a Low Carbohydrate Diet on Glycaemic Variables and Cardiovascular Risk Markers in Patients with Type 1 Diabetes: A Randomized Open-label Crossover Trial Diabetes, Obesity & Metabolism. Oct, 2017 | Pubmed ID: 28345762 Insulin and Glucagon: Partners for Life Endocrinology. Apr, 2017 | Pubmed ID: 28323959 Preserved Glucagon-like Peptide-1 Responses to Oral Glucose, but Reduced Incretin Effect, Insulin Secretion and Sensitivity in Young Asians with Type 2 Diabetes Mellitus BMJ Open Diabetes Research & Care. 2017 | Pubmed ID: 28321312 Acute Effects of Glucagon-like Peptide-1, GLP-1, and Exenatide on Mesenteric Blood Flow, Cardiovascular Parameters, and Biomarkers in Healthy Volunteers Physiological Reports. Feb, 2017 | Pubmed ID: 28235974 Differential Impact of Glucose Administered Intravenously or Orally on Bone Turnover Markers in Healthy Male Subjects Bone. Apr, 2017 | Pubmed ID: 28126633 Hypoglycemia-Associated EEG Changes Following Antecedent Hypoglycemia in Type 1 Diabetes Mellitus Diabetes Technology & Therapeutics. Feb, 2017 | Pubmed ID: 28118048 Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study Diabetes Care. Jan, 2017 | Pubmed ID: 27797928 Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells Cell Reports. Aug, 2016 | Pubmed ID: 27545881 Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation Diabetes. Nov, 2016 | Pubmed ID: 27504013 Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro Endocrinology. Oct, 2016 | Pubmed ID: 27479530 Mechanisms of Surgical Control of Type 2 Diabetes: GLP-1 is Key Factor Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. Jul, 2016 | Pubmed ID: 27313194 Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans The Journal of Clinical Endocrinology and Metabolism. Aug, 2016 | Pubmed ID: 27258938 Roles of the Gut in Glucose Homeostasis Diabetes Care. Jun, 2016 | Pubmed ID: 27222546 Searching for the Physiological Role of Glucose-dependent Insulinotropic Polypeptide Journal of Diabetes Investigation. Apr, 2016 | Pubmed ID: 27186349 The Insulinotropic Effect of Exogenous Glucagon-like Peptide-1 is Not Affected by Acute Vagotomy in Anaesthetized Pigs Experimental Physiology. Jul, 2016 | Pubmed ID: 27027735 Cholecystokinin-Induced Gallbladder Emptying and Metformin Elicit Additive Glucagon-Like Peptide-1 Responses The Journal of Clinical Endocrinology and Metabolism. May, 2016 | Pubmed ID: 27003305 Liraglutide for Treating Type 1 Diabetes Expert Opinion on Biological Therapy. 2016 | Pubmed ID: 26926662 Major Rapid Weight Loss Induces Changes in Cardiac Repolarization Journal of Electrocardiology. 2016 | Pubmed ID: 26925492 Rapid Gut Growth but Persistent Delay in Digestive Function in the Postnatal Period of Preterm Pigs American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2016 | Pubmed ID: 26822913 Peptide Production and Secretion in GLUTag, NCI-H716, and STC-1 Cells: a Comparison to Native L-cells Journal of Molecular Endocrinology. Apr, 2016 | Pubmed ID: 26819328 In Vivo and in Vitro Degradation of Peptide YY3-36 to Inactive Peptide YY3-34 in Humans American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. May, 2016 | Pubmed ID: 26818056 Do Glucagonomas Always Produce Glucagon? Bosnian Journal of Basic Medical Sciences. Feb, 2016 | Pubmed ID: 26773171 Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men PloS One. 2016 | Pubmed ID: 26752550 Efficacy and Safety of Liraglutide for Overweight Adult Patients with Type 1 Diabetes and Insufficient Glycaemic Control (Lira-1): a Randomised, Double-blind, Placebo-controlled Trial The Lancet. Diabetes & Endocrinology. Mar, 2016 | Pubmed ID: 26656289 Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study The Journal of Clinical Endocrinology and Metabolism. Feb, 2016 | Pubmed ID: 26505824 Regulation of Gut Hormone Secretion. Studies Using Isolated Perfused Intestines Peptides. Mar, 2016 | Pubmed ID: 26275337 Type 2 Diabetes Mellitus Nature Reviews. Disease Primers. Jul, 2015 | Pubmed ID: 27189025 Resistant Starch and Protein Intake Enhances Fat Oxidation and Feelings of Fullness in Lean and Overweight/obese Women Nutrition Journal. Oct, 2015 | Pubmed ID: 26514213 Inability to Match Energy Intake with Energy Expenditure at Sustained Near-maximal Rates of Energy Expenditure in Older Men During a 14-d Cycling Expedition The American Journal of Clinical Nutrition. Dec, 2015 | Pubmed ID: 26490491 Effect of Oxyntomodulin, Glucagon, GLP-1, and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite, and Resting Energy Expenditure The Journal of Clinical Endocrinology and Metabolism. Dec, 2015 | Pubmed ID: 26445112 Gastric Emptying and Disease Activity in Inflammatory Bowel Disease European Journal of Clinical Investigation. Dec, 2015 | Pubmed ID: 26426315 GLP1 and Glucagon Co-secreting Pancreatic Neuroendocrine Tumor Presenting As Hypoglycemia After Gastric Bypass Endocrinology, Diabetes & Metabolism Case Reports. 2015 | Pubmed ID: 26266036 Specific Inhibition of Bile Acid Transport Alters Plasma Lipids and GLP-1 BMC Cardiovascular Disorders. Jul, 2015 | Pubmed ID: 26197999 The Anorexic Hormone Peptide YY3-36 is Rapidly Metabolized to Inactive Peptide YY3-34 In vivo Physiological Reports. Jul, 2015 | Pubmed ID: 26197931 Liraglutide for Type 2 Diabetes and Obesity: a 2015 Update Expert Review of Cardiovascular Therapy. 2015 | Pubmed ID: 26106933 Postprandial Incretin and Islet Hormone Responses and Dipeptidyl-peptidase 4 Enzymatic Activity in Patients with Maturity Onset Diabetes of the Young European Journal of Endocrinology. Aug, 2015 | Pubmed ID: 25953829 Glucose Stimulates Neurotensin Secretion from the Rat Small Intestine by Mechanisms Involving SGLT1 and GLUT2, Leading to Cell Depolarization and Calcium Influx American Journal of Physiology. Endocrinology and Metabolism. Jun, 2015 | Pubmed ID: 25898949 Preoperative β-cell Function in Patients with Type 2 Diabetes is Important for the Outcome of Roux-en-Y Gastric Bypass Surgery The Journal of Physiology. Jul, 2015 | Pubmed ID: 25867961 Efficacy and Safety of the Glucagon-like Peptide-1 Receptor Agonist Liraglutide Added to Insulin Therapy in Poorly Regulated Patients with Type 1 Diabetes--a Protocol for a Randomised, Double-blind, Placebo-controlled Study: the Lira-1 Study BMJ Open. Apr, 2015 | Pubmed ID: 25838513 GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study Diabetes. Jul, 2015 | Pubmed ID: 25677912 Sensing of Triacylglycerol in the Gut: Different Mechanisms for Fatty Acids and 2-monoacylglycerol The Journal of Physiology. Apr, 2015 | Pubmed ID: 25639597 Measurement of the Incretin Hormones: Glucagon-like Peptide-1 and Glucose-dependent Insulinotropic Peptide Journal of Diabetes and Its Complications. Apr, 2015 | Pubmed ID: 25623632 An Analysis of Cosecretion and Coexpression of Gut Hormones from Male Rat Proximal and Distal Small Intestine Endocrinology. Mar, 2015 | Pubmed ID: 25535831 Updates in Weight Loss Surgery and Gastrointestinal Peptides Current Opinion in Endocrinology, Diabetes, and Obesity. Feb, 2015 | Pubmed ID: 25517025 Effects of Angiotensin II Receptor Blockade on Cerebral, Cardiovascular, Counter-regulatory, and Symptomatic Responses During Hypoglycaemia in Patients with Type 1 Diabetes Journal of the Renin-angiotensin-aldosterone System : JRAAS. Dec, 2015 | Pubmed ID: 25070348 A 25-year-old Woman with Type 2 Diabetes and Liver Disease Case Reports in Gastroenterology. 2014 | Pubmed ID: 25606030 High Saturated Fatty Acid Intake Induces Insulin Secretion by Elevating Gastric Inhibitory Polypeptide Levels in Healthy Individuals Nutrition Research (New York, N.Y.). Aug, 2014 | Pubmed ID: 25172378 Lactobacillus Paracasei Subsp Paracasei L. Casei W8 Suppresses Energy Intake Acutely Appetite. Nov, 2014 | Pubmed ID: 25049132 The Use of Double-balloon Enteroscopy in Retrieving Mucosal Biopsies from the Entire Human Gastrointestinal Tract Scandinavian Journal of Gastroenterology. Sep, 2014 | Pubmed ID: 24998781 Effects of PYY3-36 and GLP-1 on Energy Intake, Energy Expenditure, and Appetite in Overweight Men American Journal of Physiology. Endocrinology and Metabolism. Jun, 2014 | Pubmed ID: 24735885 Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Patients Treated with Antipsychotic Medications? Design of a Randomised, Double-blinded, Placebo-controlled Clinical Trial BMJ Open. Mar, 2014 | Pubmed ID: 24667381 GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines Peptides. May, 2014 | Pubmed ID: 24486427 Influence of GLP-1 on Myocardial Glucose Metabolism in Healthy Men During Normo- or Hypoglycemia PloS One. 2014 | Pubmed ID: 24400077 Glucagon-like Peptide-1: Effect on Pro-atrial Natriuretic Peptide in Healthy Males Endocrine Connections. 2014 | Pubmed ID: 24327600 Copenhagen Study of Overweight Patients with Coronary Artery Disease Undergoing Low Energy Diet or Interval Training: the Randomized CUT-IT Trial Protocol BMC Cardiovascular Disorders. Nov, 2013 | Pubmed ID: 24252596 Influence of Erythropoietin on Cognitive Performance During Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: a Randomized Cross-over Trial PloS One. 2013 | Pubmed ID: 23577069 Glucagon-like Peptide-1 Decreases Intracerebral Glucose Content by Activating Hexokinase and Changing Glucose Clearance During Hyperglycemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Dec, 2012 | Pubmed ID: 22929437 Continuous Parenteral and Enteral Nutrition Induces Metabolic Dysfunction in Neonatal Pigs JPEN. Journal of Parenteral and Enteral Nutrition. Sep, 2012 | Pubmed ID: 22549765 Transgenic Rescue of Adipocyte Glucose-dependent Insulinotropic Polypeptide Receptor Expression Restores High Fat Diet-induced Body Weight Gain The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22027838 Postprandial Insulin Secretion After Gastric Bypass Surgery: the Role of Glucagon-like Peptide 1 Diabetes. Sep, 2011 | Pubmed ID: 21868790 Increased Postprandial Glycaemia, Insulinemia, and Lipidemia After 10 Weeks' Sucrose-rich Diet Compared to an Artificially Sweetened Diet: a Randomised Controlled Trial Food & Nutrition Research. 2011 | Pubmed ID: 21799667 The Effect of Dietary Fish Oil in Addition to Lifestyle Counselling on Lipid Oxidation and Body Composition in Slightly Overweight Teenage Boys Journal of Nutrition and Metabolism. 2011 | Pubmed ID: 21773017 Four Weeks of Treatment with Liraglutide Reduces Insulin Dose Without Loss of Glycemic Control in Type 1 Diabetic Patients with and Without Residual Beta-cell Function Diabetes Care. Jul, 2011 | Pubmed ID: 21593296 Glucose-dependent Insulinotropic Polypeptide May Enhance Fatty Acid Re-esterification in Subcutaneous Abdominal Adipose Tissue in Lean Humans Diabetes. Sep, 2010 | Pubmed ID: 20547981 Exaggerated Glucagon-like Peptide-1 and Blunted Glucose-dependent Insulinotropic Peptide Secretion Are Associated with Roux-en-Y Gastric Bypass but Not Adjustable Gastric Banding Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery. 2007 | Pubmed ID: 17936091 Differential Postprandial Lipoprotein Responses in Type 2 Diabetic Men with and Without Clinical Evidence of a Former Myocardial Infarction The Review of Diabetic Studies : RDS. 2004 | Pubmed ID: 17491702 Investigating Hepatic Adaptations and Prediabetic Progression in Liver Diseases (Video) | JoVE Marie Winther-Sørensen1,2,3, Ida Marie Kemp1,3, Hanne Cathrine Bisgaard4, Jens Juul Holst1,5, Nicolai J. Wewer Albrechtsen2,3 1Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 3Department for Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg, 4Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 5NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen JoVE 65596 Medicine
Investigating Hepatic Adaptations and Prediabetic Progression in Liver Diseases (Video) | JoVE Marie Winther-Sørensen1,2,3, Ida Marie Kemp1,3, Hanne Cathrine Bisgaard4, Jens Juul Holst1,5, Nicolai J. Wewer Albrechtsen2,3 1Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 3Department for Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg, 4Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 5NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen JoVE 65596 Medicine