Jeremy. M. Henley MRC Centre for Synaptic Plasticity University of Bristol Biography Publications Institution JoVE Articles Jeremy. M. Henley has not added a biography. If you are Jeremy. M. Henley and would like to personalize this page please email our Author Liaison for assistance. Publications Measuring Membrane Protein Dynamics in Neurons Using Fluorescence Recovery After Photobleach Methods in Enzymology. 2012 | Pubmed ID: 22264532 Enhanced SUMOylation and SENP-1 Protein Levels Following Oxygen and Glucose Deprivation in Neurones Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2012 | Pubmed ID: 21989481 Agonist-induced PKC Phosphorylation Regulates GluK2 SUMOylation and Kainate Receptor Endocytosis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22089239 Protein SUMOylation in Spine Structure and Function Current Opinion in Neurobiology. Nov, 2011 | Pubmed ID: 22054923 Oxygen/glucose Deprivation Induces a Reduction in Synaptic AMPA Receptors on Hippocampal CA3 Neurons Mediated by MGluR1 and Adenosine A3 Receptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2011 | Pubmed ID: 21849555 Profiles of SUMO and Ubiquitin Conjugation in an Alzheimer's Disease Model Neuroscience Letters. Sep, 2011 | Pubmed ID: 21843595 Activity-dependent SUMOylation of the Brain-specific Scaffolding Protein GISP Biochemical and Biophysical Research Communications. Jun, 2011 | Pubmed ID: 21616059 Shaping the Synaptic Signal: Molecular Mobility Inside and Outside the Cleft Trends in Neurosciences. Apr, 2011 | Pubmed ID: 21470699 Routes, Destinations and Delays: Recent Advances in AMPA Receptor Trafficking Trends in Neurosciences. May, 2011 | Pubmed ID: 21420743 Ubiquitin Regulation of Neuronal Excitability Nature Neuroscience. Feb, 2011 | Pubmed ID: 21270777 Analysis of Metabotropic Glutamate Receptor 7 As a Potential Substrate for SUMOylation Neuroscience Letters. Mar, 2011 | Pubmed ID: 21255632 PICK1 Inhibition of the Arp2/3 Complex Controls Dendritic Spine Size and Synaptic Plasticity The EMBO Journal. Feb, 2011 | Pubmed ID: 21252856 Differential Roles of GRIP1a and GRIP1b in AMPA Receptor Trafficking Neuroscience Letters. Nov, 2010 | Pubmed ID: 20837103 Mechanisms, Regulation and Consequences of Protein SUMOylation The Biochemical Journal. Jun, 2010 | Pubmed ID: 20462400 Targets and Consequences of Protein SUMOylation in Neurons Brain Research Reviews. Sep, 2010 | Pubmed ID: 20382182 Protein SUMOylation in Neuropathological Conditions Drug News & Perspectives. Jun, 2009 | Pubmed ID: 19609463 Protein SUMOylation Modulates Calcium Influx and Glutamate Release from Presynaptic Terminals The European Journal of Neuroscience. Apr, 2009 | Pubmed ID: 19344328 Ischaemia Differentially Regulates GABA(B) Receptor Subunits in Organotypic Hippocampal Slice Cultures Neuropharmacology. Jun, 2009 | Pubmed ID: 19328818 Corticosterone Alters AMPAR Mobility and Facilitates Bidirectional Synaptic Plasticity PloS One. 2009 | Pubmed ID: 19305644 Dynamin-dependent Membrane Drift Recruits AMPA Receptors to Dendritic Spines The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19269965 GISP Increases Neurotransmitter Receptor Stability by Down-regulating ESCRT-mediated Lysosomal Degradation Neuroscience Letters. Mar, 2009 | Pubmed ID: 19154774 Metabotropic Glutamate Receptor-mediated LTD Involves Two Interacting Ca(2+) Sensors, NCS-1 and PICK1 Neuron. Dec, 2008 | Pubmed ID: 19109914 Investigating the Mechanisms Underlying Neuronal Death in Ischemia Using in Vitro Oxygen-glucose Deprivation: Potential Involvement of Protein SUMOylation The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Dec, 2008 | Pubmed ID: 19029060 Bidirectional Regulation of Kainate Receptor Surface Expression in Hippocampal Neurons The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18955488 Regulation of Calcium-sensing-receptor Trafficking and Cell-surface Expression by GPCRs and RAMPs Trends in Pharmacological Sciences. Dec, 2008 | Pubmed ID: 18930324 GISP Binding to TSG101 Increases GABA Receptor Stability by Down-regulating ESCRT-mediated Lysosomal Degradation Journal of Neurochemistry. Oct, 2008 | Pubmed ID: 18643869 Presynaptic MGlu1 and MGlu5 Autoreceptors Facilitate Glutamate Exocytosis from Mouse Cortical Nerve Endings Neuropharmacology. Sep, 2008 | Pubmed ID: 18625255 Analysis of SUMO-1 Modification of Neuronal Proteins Containing Consensus SUMOylation Motifs Neuroscience Letters. May, 2008 | Pubmed ID: 18400391 Increased Protein SUMOylation Following Focal Cerebral Ischemia Neuropharmacology. Feb, 2008 | Pubmed ID: 17991493 Emerging Extranuclear Roles of Protein SUMOylation in Neuronal Function and Dysfunction Nature Reviews. Neuroscience. Dec, 2007 | Pubmed ID: 17987030 Retaining Synaptic AMPARs Neuron. Sep, 2007 | Pubmed ID: 17880887 The Calcium-sensing Receptor Changes Cell Shape Via a Beta-arrestin-1 ARNO ARF6 ELMO Protein Network Journal of Cell Science. Aug, 2007 | Pubmed ID: 17623778 SUMOylation Regulates Kainate-receptor-mediated Synaptic Transmission Nature. May, 2007 | Pubmed ID: 17486098 PICK1 Interacts with Alpha7 Neuronal Nicotinic Acetylcholine Receptors and Controls Their Clustering Molecular and Cellular Neurosciences. Jun, 2007 | Pubmed ID: 17467288 GISP: a Novel Brain-specific Protein That Promotes Surface Expression and Function of GABA(B) Receptors Journal of Neurochemistry. Feb, 2007 | Pubmed ID: 17241134 A Novel Method for Monitoring the Cell Surface Expression of Heteromeric Protein Complexes in Dispersed Neurons and Acute Hippocampal Slices Journal of Neuroscience Methods. Mar, 2007 | Pubmed ID: 17083981 Differential Redistribution of Native AMPA Receptor Complexes Following LTD Induction in Acute Hippocampal Slices Neuropharmacology. Jan, 2007 | Pubmed ID: 16815481 The Schizophrenic Faces of PICK1 Trends in Pharmacological Sciences. Nov, 2006 | Pubmed ID: 17011050 Ultrastructural Localisation and Differential Agonist-induced Regulation of AMPA and Kainate Receptors Present at the Presynaptic Active Zone and Postsynaptic Density Journal of Neurochemistry. Oct, 2006 | Pubmed ID: 16903873 Lateral Diffusion Drives Constitutive Exchange of AMPA Receptors at Dendritic Spines and is Regulated by Spine Morphology The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16807334 Novel Putative Targets of N-ethylmaleimide Sensitive Fusion Protein (NSF) and Alpha/beta Soluble NSF Attachment Proteins (SNAPs) Include the Pak-binding Nucleotide Exchange Factor BetaPIX Journal of Cellular Biochemistry. Nov, 2006 | Pubmed ID: 16795052 Picking out the Details of Cerebellar LTD Neuron. Mar, 2006 | Pubmed ID: 16543122 Receptor-activity-modifying Proteins Are Required for Forward Trafficking of the Calcium-sensing Receptor to the Plasma Membrane Journal of Cell Science. Oct, 2005 | Pubmed ID: 16188935 PICK1 is a Calcium-sensor for NMDA-induced AMPA Receptor Trafficking The EMBO Journal. Sep, 2005 | Pubmed ID: 16138078 Calcium As an Extracellular Signalling Molecule: Perspectives on the Calcium Sensing Receptor in the Brain Comptes Rendus Biologies. Aug, 2005 | Pubmed ID: 16125647 Hippocalcin Functions As a Calcium Sensor in Hippocampal LTD Neuron. Aug, 2005 | Pubmed ID: 16102532 The Molecular Pharmacology and Cell Biology of Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors Pharmacological Reviews. Jun, 2005 | Pubmed ID: 15914469 Syntenin is Involved in the Developmental Regulation of Neuronal Membrane Architecture Molecular and Cellular Neurosciences. Apr, 2005 | Pubmed ID: 15797720 Profile of Changes in Gene Expression in Cultured Hippocampal Neurones Evoked by the GABAB Receptor Agonist Baclofen Physiological Genomics. Jun, 2005 | Pubmed ID: 15784695 Activity-dependent Endocytic Sorting of Kainate Receptors to Recycling or Degradation Pathways The EMBO Journal. Dec, 2004 | Pubmed ID: 15549132 Development of GABAB Subunits and Functional GABAB Receptors in Rat Cultured Hippocampal Neurons Neuropharmacology. Sep, 2004 | Pubmed ID: 15380367 The PDZ Domain of PICK1 Differentially Accepts Protein Kinase C-alpha and GluR2 As Interacting Ligands The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15247289 Regulation of Synaptic Strength and AMPA Receptor Subunit Composition by PICK1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15190111 Removal of AMPA Receptors (AMPARs) from Synapses is Preceded by Transient Endocytosis of Extrasynaptic AMPARs The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15175386 It's Green Outside: Tracking Cell Surface Proteins with PH-sensitive GFP Trends in Neurosciences. May, 2004 | Pubmed ID: 15111007 Characterization of the Intracellular Transport of GluR1 and GluR2 Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12909632 Acetylcholinesterase Promotes Neurite Elongation, Synapse Formation, and Surface Expression of AMPA Receptors in Hippocampal Neurones Molecular and Cellular Neurosciences. May, 2003 | Pubmed ID: 12799140 Regulation of Kainate Receptors by Protein Kinase C and Metabotropic Glutamate Receptors The Journal of Physiology. May, 2003 | Pubmed ID: 12640005 Proteins Interactions Implicated in AMPA Receptor Trafficking: a Clear Destination and an Improving Route Map Neuroscience Research. Mar, 2003 | Pubmed ID: 12631461 Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP Neuron. Feb, 2003 | Pubmed ID: 12597860 AMPA Receptor Potentiation by Acetylcholinesterase is Age-dependently Upregulated at Synaptogenesis Sites of the Rat Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Feb, 2003 | Pubmed ID: 12565696 Proteins Involved in the Trafficking and Functional Synaptic Expression of AMPA and KA Receptors TheScientificWorldJournal. Feb, 2002 | Pubmed ID: 12806030 The PDZ Proteins PICK1, GRIP, and Syntenin Bind Multiple Glutamate Receptor Subtypes. Analysis of PDZ Binding Motifs The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11891216 Localization and Quantitative Autoradiography of Glutamatergic Ligand Binding Sites in Chick Brain The European Journal of Neuroscience. Sep, 1989 | Pubmed ID: 12106137 Lateral Diffusion and Exocytosis of Membrane Proteins in Cultured Neurons Assessed using Fluorescence Recovery and Fluorescence-loss Photobleaching Keri L. Hildick1, Inmaculada M. González-González1, Frédéric Jaskolski1, Jeremy. M. Henley1 1MRC Centre for Synaptic Plasticity, University of Bristol JoVE 3747 Neuroscience
Lateral Diffusion and Exocytosis of Membrane Proteins in Cultured Neurons Assessed using Fluorescence Recovery and Fluorescence-loss Photobleaching Keri L. Hildick1, Inmaculada M. González-González1, Frédéric Jaskolski1, Jeremy. M. Henley1 1MRC Centre for Synaptic Plasticity, University of Bristol JoVE 3747 Neuroscience