Jeremy Allegood VCU Lipidomics/Metabolomics Shared Resource Virginia Commonwealth University School of Medicine Biography Publications Institution JoVE Articles Jeremy Allegood has not added a biography. If you are Jeremy Allegood and would like to personalize this page please email our Author Liaison for assistance. Publications A Simple Method for Sphingolipid Analysis of Tissues Embedded in Optimal Cutting Temperature Compound Journal of Lipid Research. 06, 2020 | Pubmed ID: 32341007 Dynamics of Sphingolipids and the Serine Palmitoyltransferase Complex in Rat Oligodendrocytes During Myelination Journal of Lipid Research. 04, 2020 | Pubmed ID: 32041816 Sphingosine Kinase 2 Phosphorylation of FTY720 is Unnecessary for Prevention of Light-Induced Retinal Damage Scientific Reports. 05, 2019 | Pubmed ID: 31123291 Sphingosine-1-phosphate Signalling Drives an Angiogenic Transcriptional Programme in Diffuse Large B Cell Lymphoma Leukemia. 12, 2019 | Pubmed ID: 31097785 Analysis of Sphingolipid Composition in Human Vitreous from Control and Diabetic Individuals Journal of Diabetes and Its Complications. 03, 2019 | Pubmed ID: 30630661 Clinical Signs of Meibomian Gland Dysfunction (MGD) Are Associated with Changes in Meibum Sphingolipid Composition The Ocular Surface. 04, 2019 | Pubmed ID: 30553001 Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis Cancer Research. Apr, 2018 | Pubmed ID: 29351902 The Putative Flippase Apt1 is Required for Intracellular Membrane Architecture and Biosynthesis of Polysaccharide and Lipids in Cryptococcus Neoformans Biochimica Et Biophysica Acta. Dec, 2017 | Pubmed ID: 29291962 Analysis of Sphingolipids in Human Corneal Fibroblasts from Normal and Keratoconus Patients Journal of Lipid Research. Apr, 2017 | Pubmed ID: 28188148 Sphingosine-1-phosphate in the Lymphatic Fluid Determined by Novel Methods Heliyon. Dec, 2016 | Pubmed ID: 28054036 ORMDL Proteins Regulate Ceramide Levels During Sterile Inflammation Journal of Lipid Research. 08, 2016 | Pubmed ID: 27313060 Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods Journal of Mammary Gland Biology and Neoplasia. 06, 2016 | Pubmed ID: 27194029 Sphingolipid Profile Alters in Retinal Dystrophic P23H-1 Rats and Systemic FTY720 Can Delay Retinal Degeneration Journal of Lipid Research. 05, 2016 | Pubmed ID: 26947037 Aberrant ORM (yeast)-like Protein Isoform 3 (ORMDL3) Expression Dysregulates Ceramide Homeostasis in Cells and Ceramide Exacerbates Allergic Asthma in Mice The Journal of Allergy and Clinical Immunology. Oct, 2015 | Pubmed ID: 25842287 Uncleaved ApoM Signal Peptide is Required for Formation of Large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL Particles The Journal of Biological Chemistry. Mar, 2015 | Pubmed ID: 25627684 Description of the Sphingolipid Content and Subspecies in the Diabetic Cornea Current Eye Research. 2015 | Pubmed ID: 25426847 Role of Sphingosine Kinase 1 and Sphingosine-1-phosphate in CD40 Signaling and IgE Class Switching FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2014 | Pubmed ID: 25002116 Active, Phosphorylated Fingolimod Inhibits Histone Deacetylases and Facilitates Fear Extinction Memory Nature Neuroscience. Jul, 2014 | Pubmed ID: 24859201 Memo Has a Novel Role in S1P Signaling and is [corrected] Crucial for Vascular Development PloS One. 2014 | Pubmed ID: 24714781 K63-linked Polyubiquitination of Transcription Factor IRF1 is Essential for IL-1-induced Production of Chemokines CXCL10 and CCL5 Nature Immunology. Mar, 2014 | Pubmed ID: 24464131 Hepatic Apolipoprotein M (apoM) Overexpression Stimulates Formation of Larger ApoM/sphingosine 1-phosphate-enriched Plasma High Density Lipoprotein The Journal of Biological Chemistry. Jan, 2014 | Pubmed ID: 24318881 Molecular Mechanism of Sphingosine-1-phosphate Action in Duchenne Muscular Dystrophy Disease Models & Mechanisms. Jan, 2014 | Pubmed ID: 24077965 Sphingosine-1-phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-associated Cancer Cancer Cell. Jan, 2013 | Pubmed ID: 23273921 Spns2, a Transporter of Phosphorylated Sphingoid Bases, Regulates Their Blood and Lymph Levels, and the Lymphatic Network FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2013 | Pubmed ID: 23180825 A Specific Sphingosine Kinase 1 Inhibitor Attenuates Airway Hyperresponsiveness and Inflammation in a Mast Cell-dependent Murine Model of Allergic Asthma The Journal of Allergy and Clinical Immunology. Feb, 2013 | Pubmed ID: 22939756 Sphingosine-1-phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis Cancer Research. Feb, 2012 | Pubmed ID: 22298596 Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22052905 Factors to Consider in Using [U-C]palmitate for Analysis of Sphingolipid Biosynthesis by Tandem Mass Spectrometry Journal of Lipid Research. Aug, 2011 | Pubmed ID: 21586681 Sphingosine-1-phosphate Produced by Sphingosine Kinase 2 in Mitochondria Interacts with Prohibitin 2 to Regulate Complex IV Assembly and Respiration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2011 | Pubmed ID: 20959514 Sphingosine-1-phosphate is a Missing Cofactor for the E3 Ubiquitin Ligase TRAF2 Nature. Jun, 2010 | Pubmed ID: 20577214 Estradiol Induces Export of Sphingosine 1-phosphate from Breast Cancer Cells Via ABCC1 and ABCG2 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20110355 Use of High Performance Liquid Chromatography-electrospray Ionization-tandem Mass Spectrometry for the Analysis of Ceramide-1-phosphate Levels Journal of Lipid Research. Mar, 2010 | Pubmed ID: 19654423 Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-phosphate Science (New York, N.Y.). Sep, 2009 | Pubmed ID: 19729656 Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts Cancer Research. Sep, 2009 | Pubmed ID: 19723667 Sphingolipidomics: Methods for the Comprehensive Analysis of Sphingolipids Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Sep, 2009 | Pubmed ID: 19147416 Preparation of Human Tissues Embedded in Optimal Cutting Temperature Compound for Mass Spectrometry Analysis April E. Boyd1, Jeremy Allegood2, Santiago Lima1,3 1Department of Biology, Virginia Commonwealth University, 2VCU Lipidomics/Metabolomics Shared Resource, Virginia Commonwealth University School of Medicine, 3Massey Cancer Center JoVE 62552 Cancer Research
Preparation of Human Tissues Embedded in Optimal Cutting Temperature Compound for Mass Spectrometry Analysis April E. Boyd1, Jeremy Allegood2, Santiago Lima1,3 1Department of Biology, Virginia Commonwealth University, 2VCU Lipidomics/Metabolomics Shared Resource, Virginia Commonwealth University School of Medicine, 3Massey Cancer Center JoVE 62552 Cancer Research