Johannes Boltze Ischemia Research Unit Fraunhofer Institute for Cell Therapy and Immunology Biography Publications Institution JoVE Articles Johannes Boltze has not added a biography. If you are Johannes Boltze and would like to personalize this page please email our Author Liaison for assistance. Publications Improved Prediction of Complex Diseases by Common Genetic Markers: State of the Art and Further Perspectives Human Genetics. Feb, 2016 | Pubmed ID: 26839113 High Acceptance of an Early Dyslexia Screening Test Involving Genetic Analyses in Germany European Journal of Human Genetics : EJHG. Feb, 2016 | Pubmed ID: 26036858 Arterial Hypertension Aggravates Innate Immune Responses After Experimental Stroke Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26640428 Working-memory Endophenotype and Dyslexia-associated Genetic Variant Predict Dyslexia Phenotype Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. Oct, 2015 | Pubmed ID: 26283516 The Dark Side of the Force - Constraints and Complications of Cell Therapies for Stroke Frontiers in Neurology. 2015 | Pubmed ID: 26257702 Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines Journal of Neuropathology and Experimental Neurology. Sep, 2015 | Pubmed ID: 26247394 Simultaneous PET/MRI in Stroke: a Case Series Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2015 | Pubmed ID: 26174332 Stem Cell-Based Tissue Replacement After Stroke: Factual Necessity or Notorious Fiction? Stroke; a Journal of Cerebral Circulation. Aug, 2015 | Pubmed ID: 26106118 A Stereotaxic, Population-averaged T1w Ovine Brain Atlas Including Cerebral Morphology and Tissue Volumes Frontiers in Neuroanatomy. 2015 | Pubmed ID: 26089780 Genetic Dyslexia Risk Variant is Related to Neural Connectivity Patterns Underlying Phonological Awareness in Children NeuroImage. Sep, 2015 | Pubmed ID: 26080313 The Cerebral Embolism Evoked by Intra-arterial Delivery of Allogeneic Bone Marrow Mesenchymal Stem Cells in Rats is Related to Cell Dose and Infusion Velocity Stem Cell Research & Therapy. 2015 | Pubmed ID: 25971703 Infarction of the Corpus Callosum: a Retrospective Clinical Investigation PloS One. 2015 | Pubmed ID: 25785450 Granulocyte Colony-stimulating Factor and Bone Marrow Mononuclear Cells for Stroke Treatment in the Aged Brain Current Neurovascular Research. 2015 | Pubmed ID: 25760217 Cortical Differences in Preliterate Children at Familiar Risk of Dyslexia Are Similar to Those Observed in Dyslexic Readers Brain : a Journal of Neurology. Sep, 2015 | Pubmed ID: 25701065 Granulocyte Colony-stimulating Factor (G-CSF) Treatment in Combination with Transplantation of Bone Marrow Cells is Not Superior to G-CSF Treatment Alone After Cortical Stroke in Spontaneously Hypertensive Rats Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25538562 Spontaneous White Matter Damage, Cognitive Decline and Neuroinflammation in Middle-aged Hypertensive Rats: an Animal Model of Early-stage Cerebral Small Vessel Disease Acta Neuropathologica Communications. 2014 | Pubmed ID: 25519173 Flow Cytometric Characterization of Brain Dendritic Cell Subsets After Murine Stroke Experimental & Translational Stroke Medicine. 2014 | Pubmed ID: 25396039 Transient but Not Permanent Benefit of Neuronal Progenitor Cell Therapy After Traumatic Brain Injury: Potential Causes and Translational Consequences Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25352780 Multimodal Approaches for Regenerative Stroke Therapies: Combination of Granulocyte Colony-Stimulating Factor with Bone Marrow Mesenchymal Stem Cells is Not Superior to G-CSF Alone Frontiers in Aging Neuroscience. 2014 | Pubmed ID: 25002846 Bone Marrow Cell Transplantation Time-dependently Abolishes Efficacy of Granulocyte Colony-stimulating Factor After Stroke in Hypertensive Rats Stroke; a Journal of Cerebral Circulation. Aug, 2014 | Pubmed ID: 24984745 Mesenchymal Stromal Cells in Stroke: Improvement of Motor Recovery or Functional Compensation? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2014 | Pubmed ID: 24849662 The Ovine Cerebral Venous System: Comparative Anatomy, Visualization, and Implications for Translational Research PloS One. 2014 | Pubmed ID: 24736654 Modelling Hematological Parameters After Total Body Irradiation International Journal of Radiation Biology. Jul, 2014 | Pubmed ID: 24605769 Astrocytic Mitochondrial Membrane Hyperpolarization Following Extended Oxygen and Glucose Deprivation PloS One. 2014 | Pubmed ID: 24587410 Temporal Dynamics of Glyoxalase 1 in Secondary Neuronal Injury PloS One. 2014 | Pubmed ID: 24498315 Bone Marrow-derived Mononuclear Cells Do Not Exert Acute Neuroprotection After Stroke in Spontaneously Hypertensive Rats Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 24409120 Preclinical Phase III Trials in Translational Stroke Research: Call for Collective Design of Framework and Guidelines Stroke; a Journal of Cerebral Circulation. Feb, 2014 | Pubmed ID: 24407954 Allometric Dose Retranslation Unveiled Substantial Immunological Side Effects of Granulocyte Colony-stimulating Factor After Stroke Stroke; a Journal of Cerebral Circulation. Feb, 2014 | Pubmed ID: 24407949 Sterile Inflammation After Permanent Distal MCA Occlusion in Hypertensive Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2014 | Pubmed ID: 24220169 Continuous Adenosine A2A Receptor Antagonism After Focal Cerebral Ischemia in Spontaneously Hypertensive Rats Naunyn-Schmiedeberg's Archives of Pharmacology. Feb, 2014 | Pubmed ID: 24170241 Transplantation of Cryopreserved Human Umbilical Cord Blood Mononuclear Cells Does Not Induce Sustained Recovery After Experimental Stroke in Spontaneously Hypertensive Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2014 | Pubmed ID: 24169850 Stroke Treatment Academic Industry Roundtable: Research Priorities in the Assessment of Neurothrombectomy Devices Stroke; a Journal of Cerebral Circulation. Dec, 2013 | Pubmed ID: 24193797 Imaging of VSOP Labeled Stem Cells in Agarose Phantoms with Susceptibility Weighted and T2* Weighted MR Imaging at 3T: Determination of the Detection Limit PloS One. 2013 | Pubmed ID: 23667503 A Concerted Appeal for International Cooperation in Preclinical Stroke Research Stroke; a Journal of Cerebral Circulation. Jun, 2013 | Pubmed ID: 23598526 Object-based Analysis of Astroglial Reaction and Astrocyte Subtype Morphology After Ischemic Brain Injury Acta Neurobiologiae Experimentalis. 2013 | Pubmed ID: 23595285 Density Gradient Centrifugation Compromises Bone Marrow Mononuclear Cell Yield PloS One. 2012 | Pubmed ID: 23236366 Isolation of Inflammatory Cells from Rat Brain Tissue After Stroke Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 23031714 Impact of Age on the Efficacy of Bone Marrow Mononuclear Cell Transplantation in Experimental Stroke Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 22920434 Neurovascular Pathophysiology in Cerebral Ischemia, Dementia and the Ageing Brain - Current Trends in Basic, Translational and Clinical Research Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 22883324 Association of Rs2069459 in the CDK5 Gene with Dyslexia in a German Cohort Psychiatric Genetics. Dec, 2012 | Pubmed ID: 22547140 Changes in T2 Relaxation Time After Stroke Reflect Clearing Processes NeuroImage. Jul, 2012 | Pubmed ID: 22534339 Inhalation of Nitric Oxide Prevents Ischemic Brain Damage in Experimental Stroke by Selective Dilatation of Collateral Arterioles Circulation Research. Mar, 2012 | Pubmed ID: 22207711 Determination of the Therapeutic Time Window for Human Umbilical Cord Blood Mononuclear Cell Transplantation Following Experimental Stroke in Rats Cell Transplantation. 2012 | Pubmed ID: 22182968 Association Study of a Functional Genetic Variant in KIAA0319 in German Dyslexics Psychiatric Genetics. Aug, 2012 | Pubmed ID: 21934641 Assessment of Neuroprotective Effects of Human Umbilical Cord Blood Mononuclear Cell Subpopulations in Vitro and in Vivo Cell Transplantation. 2012 | Pubmed ID: 21929866 Imaging Genetics of FOXP2 in Dyslexia European Journal of Human Genetics : EJHG. Feb, 2012 | Pubmed ID: 21897444 Histopathological Investigation of Different MCAO Modalities and Impact of Autologous Bone Marrow Mononuclear Cell Administration in an Ovine Stroke Model Translational Stroke Research. Sep, 2011 | Pubmed ID: 23440305 Early Outcome and Blood-brain Barrier Integrity After Co-administered Thrombolysis and Hyperbaric Oxygenation in Experimental Stroke Experimental & Translational Stroke Medicine. 2011 | Pubmed ID: 21679435 Recent Advances in Basic and Translational Stroke Research Expert Review of Neurotherapeutics. Feb, 2011 | Pubmed ID: 21306206 Cleaved Caspase-3 Expression After Experimental Stroke Exhibits Different Phenotypes and is Predominantly Non-apoptotic Brain Research. Mar, 2011 | Pubmed ID: 21256117 Intravenous Human Umbilical Cord Blood Transplantation for Stroke: Impact on Infarct Volume and Caspase-3-dependent Cell Death in Spontaneously Hypertensive Rats Experimental Neurology. Jan, 2011 | Pubmed ID: 21087606 Long-term Benefit of Human Fetal Neuronal Progenitor Cell Transplantation in a Clinically Adapted Model After Traumatic Brain Injury Journal of Neurotrauma. Mar, 2011 | Pubmed ID: 21083415 Characterization of Murine Non-adherent Bone Marrow Cells Leading to Recovery of Endogenous Hematopoiesis Cellular and Molecular Life Sciences : CMLS. Dec, 2010 | Pubmed ID: 20556631 No Juvenile Arterial Hypertension in Sheep Multiples Despite Reduced Nephron Numbers Pediatric Nephrology (Berlin, Germany). Sep, 2010 | Pubmed ID: 20386927 Transplantation of Placenta-derived Mesenchymal Stromal Cells Upon Experimental Stroke in Rats Brain Research. Feb, 2010 | Pubmed ID: 20004649 Impact of Magnetic Labeling on Human and Mouse Stem Cells and Their Long-term Magnetic Resonance Tracking in a Rat Model of Parkinson Disease Molecular Imaging. May-Jun, 2009 | Pubmed ID: 19723474 Autologous Umbilical Cord Blood Mononuclear Cell Transplantation Preserves Right Ventricular Function in a Novel Model of Chronic Right Ventricular Volume Overload Cell Transplantation. 2009 | Pubmed ID: 19500473 Pressure-volume Loops: Feasible for the Evaluation of Right Ventricular Function in an Experimental Model of Acute Pulmonary Regurgitation? Interactive Cardiovascular and Thoracic Surgery. Aug, 2009 | Pubmed ID: 19470501 Triple Fluorescence Labelling of Neuronal, Glial and Vascular Markers Revealing Pathological Alterations in Various Animal Models Journal of Chemical Neuroanatomy. Mar, 2009 | Pubmed ID: 19028564 Neuronal Hypoxia in Vitro: Investigation of Therapeutic Principles of HUCB-MNC and CD133+ Stem Cells BMC Neuroscience. 2008 | Pubmed ID: 18803816 Permanent Middle Cerebral Artery Occlusion in Sheep: a Novel Large Animal Model of Focal Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Dec, 2008 | Pubmed ID: 18698332 Cord Blood Cell Therapy Alters LV Remodeling and Cytokine Expression but Does Not Improve Heart Function After Myocardial Infarction in Rats Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2008 | Pubmed ID: 18453747 Evidence for Neuroprotective Properties of Human Umbilical Cord Blood Cells After Neuronal Hypoxia in Vitro BMC Neuroscience. 2008 | Pubmed ID: 18312640 The Stairway: a Novel Behavioral Test Detecting Sensomotoric Stroke Deficits in Rats Artificial Organs. Oct, 2006 | Pubmed ID: 17026574 Experimental Treatment of Stroke in Spontaneously Hypertensive Rats by CD34+ and CD34- Cord Blood Cells German Medical Science : GMS E-journal. 2005 | Pubmed ID: 19675726 Isolering och flödescytometrisk analys av immunceller från ischemisk Mouse Brain Claudia Pösel*1, Karoline Möller*1, Johannes Boltze1,2, Daniel-Christoph Wagner1, Gesa Weise1,3 1Ischemia Research Unit, Fraunhofer Institute for Cell Therapy and Immunology, 2Fraunhofer Research Institution for Marine Biotechnology, University of Lubeck, 3Department of Neurology, University of Leipzig Immunology and Infection
Isolering och flödescytometrisk analys av immunceller från ischemisk Mouse Brain Claudia Pösel*1, Karoline Möller*1, Johannes Boltze1,2, Daniel-Christoph Wagner1, Gesa Weise1,3 1Ischemia Research Unit, Fraunhofer Institute for Cell Therapy and Immunology, 2Fraunhofer Research Institution for Marine Biotechnology, University of Lubeck, 3Department of Neurology, University of Leipzig Immunology and Infection