Kebin Liu Department of Biochemistry and Molecular Biology, Medical College of Georgia Augusta University Biography Publications Institution JoVE Articles Kebin Liu has not added a biography. If you are Kebin Liu and would like to personalize this page please email our Author Liaison for assistance. Publications Ceramide Mediates FasL-induced Caspase 8 Activation in Colon Carcinoma Cells to Enhance FasL-induced Cytotoxicity by Tumor-specific Cytotoxic T Lymphocytes Scientific Reports. 2016 | Pubmed ID: 27487939 Antitumor Activity of Sulfated Hyaluronic Acid Fragments in Pre-clinical Models of Bladder Cancer Oncotarget. Jul, 2016 | Pubmed ID: 27419371 5-Fluorouracil Targets Thymidylate Synthase in the Selective Suppression of TH17 Cell Differentiation Oncotarget. Apr, 2016 | Pubmed ID: 27027355 NF-κB Functions As a Molecular Link Between Tumor Cells and Th1/Tc1 T Cells in the Tumor Microenvironment to Exert Radiation-mediated Tumor Suppression Oncotarget. Apr, 2016 | Pubmed ID: 27014915 The NF-κB P65 and P50 Homodimer Cooperate with IRF8 to Activate INOS Transcription BMC Cancer. 2015 | Pubmed ID: 26497740 Epigenetic Regulation of Apoptosis and Cell Cycle Regulatory Genes in Human Colon Carcinoma Cells Genomics Data. Sep, 2015 | Pubmed ID: 26309812 B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens Journal of Immunology (Baltimore, Md. : 1950). Sep, 2015 | Pubmed ID: 26216892 H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015 | Pubmed ID: 26136424 Myeloid Cell-derived Inducible Nitric Oxide Synthase Suppresses M1 Macrophage Polarization Nature Communications. 2015 | Pubmed ID: 25813085 IFNγ Induces DNA Methylation-Silenced GPR109A Expression Via PSTAT1/p300 and H3K18 Acetylation in Colon Cancer Cancer Immunology Research. Jul, 2015 | Pubmed ID: 25735954 IFN Regulatory Factor 8 Represses GM-CSF Expression in T Cells to Affect Myeloid Cell Lineage Differentiation Journal of Immunology (Baltimore, Md. : 1950). Mar, 2015 | Pubmed ID: 25646302 Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-cell Responses Through the PD-1-PD-L1 Axis Cancer Research. Jul, 2014 | Pubmed ID: 24780756 Tubular P53 Regulates Multiple Genes to Mediate AKI Journal of the American Society of Nephrology : JASN. Oct, 2014 | Pubmed ID: 24700871 Ceramide Targets XIAP and CIAP1 to Sensitize Metastatic Colon and Breast Cancer Cells to Apoptosis Induction to Suppress Tumor Progression BMC Cancer. 2014 | Pubmed ID: 24422988 GCN2-dependent Metabolic Stress is Essential for Endotoxemic Cytokine Induction and Pathology Molecular and Cellular Biology. Feb, 2014 | Pubmed ID: 24248597 Long Pentraxin PTX3 Attenuates Ischemia Reperfusion Injury in a Cardiac Transplantation Model Transplant International : Official Journal of the European Society for Organ Transplantation. Jan, 2014 | Pubmed ID: 24112130 Epigenetics and Colorectal Cancer Pathogenesis Cancers. 2013 | Pubmed ID: 24216997 Myeloid-derived Suppressor Cell Development is Regulated by a STAT/IRF-8 Axis The Journal of Clinical Investigation. Oct, 2013 | Pubmed ID: 24091328 Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23677993 Hmgb1-TLR4-IL-23-IL-17A Axis Promote Ischemia-reperfusion Injury in a Cardiac Transplantation Model Transplantation. Jun, 2013 | Pubmed ID: 23677049 Lymphotoxin β Receptor Mediates Caspase-dependent Tumor Cell Apoptosis in Vitro and Tumor Suppression in Vivo Despite Induction of NF-κB Activation Carcinogenesis. May, 2013 | Pubmed ID: 23349015 Unphosphorylated STAT1 Promotes Sarcoma Development Through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance Cancer Research. Sep, 2012 | Pubmed ID: 22805310 NF-κB Directly Regulates Fas Transcription to Modulate Fas-mediated Apoptosis and Tumor Suppression The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22669972 Type 2 CGMP-dependent Protein Kinase Regulates Proliferation and Differentiation in the Colonic Mucosa American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2012 | Pubmed ID: 22556146 Butyrate Suppresses Colonic Inflammation Through HDAC1-dependent Fas Upregulation and Fas-mediated Apoptosis of T Cells American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2012 | Pubmed ID: 22517765 Decitabine and Vorinostat Cooperate to Sensitize Colon Carcinoma Cells to Fas Ligand-induced Apoptosis in Vitro and Tumor Suppression in Vivo Journal of Immunology (Baltimore, Md. : 1950). May, 2012 | Pubmed ID: 22461695 Cutting Edge: IRF8 Regulates Bax Transcription in Vivo in Primary Myeloid Cells Journal of Immunology (Baltimore, Md. : 1950). Nov, 2011 | Pubmed ID: 21949018 Verticillin A Overcomes Apoptosis Resistance in Human Colon Carcinoma Through DNA Methylation-dependent Upregulation of BNIP3 Cancer Research. Nov, 2011 | Pubmed ID: 21911457 Cyclic 3',5'-guanosine Monophosphate-dependent Protein Kinase Inhibits Colon Cancer Cell Adaptation to Hypoxia Cancer. Dec, 2011 | Pubmed ID: 21563174 IRF8 Regulates Acid Ceramidase Expression to Mediate Apoptosis and Suppresses Myelogeneous Leukemia Cancer Research. Apr, 2011 | Pubmed ID: 21487040 TNFα Cooperates with IFN-γ to Repress Bcl-xL Expression to Sensitize Metastatic Colon Carcinoma Cells to TRAIL-mediated Apoptosis PloS One. 2011 | Pubmed ID: 21264227 Rapid and Transient Recruitment of DNMT1 to DNA Double-strand Breaks is Mediated by Its Interaction with Multiple Components of the DNA Damage Response Machinery Human Molecular Genetics. Jan, 2011 | Pubmed ID: 20940144 Sigma Receptor 1 Modulates Endoplasmic Reticulum Stress in Retinal Neurons Investigative Ophthalmology & Visual Science. Jan, 2011 | Pubmed ID: 20811050 Role of Apoptosis Resistance in Immune Evasion and Metastasis of Colorectal Cancer World Journal of Gastrointestinal Oncology. Nov, 2010 | Pubmed ID: 21160903 IFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-specific T Cells PloS One. 2010 | Pubmed ID: 21124930 TRAIL and Doxorubicin Combination Induces Proapoptotic and Antiangiogenic Effects in Soft Tissue Sarcoma in Vivo Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2010 | Pubmed ID: 20406839 Autophagy is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-reperfusion Injury The American Journal of Pathology. Mar, 2010 | Pubmed ID: 20075199 Colonic Gene Expression in Conventional and Germ-free Mice with a Focus on the Butyrate Receptor GPR109A and the Butyrate Transporter SLC5A8 Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Mar, 2010 | Pubmed ID: 20033346 Interferon Regulatory Factor-8 Modulates the Development of Tumour-induced CD11b+Gr-1+ Myeloid Cells Journal of Cellular and Molecular Medicine. Sep, 2009 | Pubmed ID: 20196788 Extracellular Signal-regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining Slug Expression Cancer Research. Dec, 2009 | Pubmed ID: 19920183 Absence of Iron-regulatory Protein Hfe Results in Hyperproliferation of Retinal Pigment Epithelium: Role of Cystine/glutamate Exchanger The Biochemical Journal. Dec, 2009 | Pubmed ID: 19715555 Endogenous Elevation of Homocysteine Induces Retinal Neuron Death in the Cystathionine-beta-synthase Mutant Mouse Investigative Ophthalmology & Visual Science. Sep, 2009 | Pubmed ID: 19357353 GPR109A is a G-protein-coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions As a Tumor Suppressor in Colon Cancer Research. Apr, 2009 | Pubmed ID: 19276343 Interferon Regulatory Factor-8 Modulates the Development of Tumor-Induced CD11bGr-1 Myeloid Cells Journal of Cellular and Molecular Medicine. Jan, 2009 | Pubmed ID: 19187118 IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor-initiated Apoptosis Via Repression of FLICE-like Protein Expression Cancer Research. Feb, 2009 | Pubmed ID: 19155307 The Copper Transporter Ctr1 Contributes to Cisplatin Uptake by Renal Tubular Cells During Cisplatin Nephrotoxicity American Journal of Physiology. Renal Physiology. Mar, 2009 | Pubmed ID: 19144690 DNA Methylation Represses IFN-gamma-induced and Signal Transducer and Activator of Transcription 1-mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells Molecular Cancer Research : MCR. Dec, 2008 | Pubmed ID: 19074829 Expression of Cyclic Guanosine Monophosphate-dependent Protein Kinase in Metastatic Colon Carcinoma Cells Blocks Tumor Angiogenesis Cancer. Apr, 2008 | Pubmed ID: 18260092 Effects of Targeted Bcl-2 Expression in Mitochondria or Endoplasmic Reticulum on Renal Tubular Cell Apoptosis American Journal of Physiology. Renal Physiology. Mar, 2008 | Pubmed ID: 18160625 Downregulation of IFN-gammaR in Association with Loss of Fas Function is Linked to Tumor Progression International Journal of Cancer. Journal International Du Cancer. Jan, 2008 | Pubmed ID: 17918178 Host Immunosurveillance Controls Tumor Growth Via IFN Regulatory Factor-8 Dependent Mechanisms Cancer Research. Nov, 2007 | Pubmed ID: 17974984 IFN Regulatory Factor 8 Mediates Apoptosis in Nonhemopoietic Tumor Cells Via Regulation of Fas Expression Journal of Immunology (Baltimore, Md. : 1950). Oct, 2007 | Pubmed ID: 17878376 Targeting Lymphotoxin Beta Receptor with Tumor-specific T Lymphocytes for Tumor Regression Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2007 | Pubmed ID: 17785576 Repression of IFN Regulatory Factor 8 by DNA Methylation is a Molecular Determinant of Apoptotic Resistance and Metastatic Phenotype in Metastatic Tumor Cells Cancer Research. Apr, 2007 | Pubmed ID: 17409439 [Aromatic Constituents in Fresh Leaves of Lingtou Dancong Tea Under Basilepta Melanopus Lefevre Stress] Ying Yong Sheng Tai Xue Bao = The Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. Nov, 2006 | Pubmed ID: 17269334 A2A Adenosine Receptor Protects Tumors from Antitumor T Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16916931 CTL Adoptive Immunotherapy Concurrently Mediates Tumor Regression and Tumor Escape Journal of Immunology (Baltimore, Md. : 1950). Mar, 2006 | Pubmed ID: 16517705 Immune Selection and Emergence of Aggressive Tumor Variants As Negative Consequences of Fas-mediated Cytotoxicity and Altered IFN-gamma-regulated Gene Expression Cancer Research. May, 2005 | Pubmed ID: 15899830 Cooperative Disengagement of Fas and Intercellular Adhesion Molecule-1 Function in Neoplastic Cells Confers Enhanced Colonization Efficiency Cancer Research. Feb, 2005 | Pubmed ID: 15705906 Exposure of Human Primary Colon Carcinoma Cells to Anti-Fas Interactions Influences the Emergence of Pre-existing Fas-resistant Metastatic Subpopulations Journal of Immunology (Baltimore, Md. : 1950). Oct, 2003 | Pubmed ID: 14530339 Irradiation of Tumor Cells Up-regulates Fas and Enhances CTL Lytic Activity and CTL Adoptive Immunotherapy Journal of Immunology (Baltimore, Md. : 1950). Jun, 2003 | Pubmed ID: 12794167 Coordinate Regulation of IFN Consensus Sequence-binding Protein and Caspase-1 in the Sensitization of Human Colon Carcinoma Cells to Fas-mediated Apoptosis by IFN-gamma Journal of Immunology (Baltimore, Md. : 1950). Jun, 2003 | Pubmed ID: 12794166 Alterations in Fas Expression Are Characteristic Of, but Not Solely Responsible For, Enhanced Metastatic Competence Journal of Immunology (Baltimore, Md. : 1950). Jun, 2003 | Pubmed ID: 12794124 IL-15 is a Growth Factor and an Activator of CD8 Memory T Cells Annals of the New York Academy of Sciences. Dec, 2002 | Pubmed ID: 12538153 IL-15 Mimics T Cell Receptor Crosslinking in the Induction of Cellular Proliferation, Gene Expression, and Cytotoxicity in CD8+ Memory T Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11972069 En ortotopiske Mouse Model of Spontan Breast Cancer Metastase Amy V. Paschall1,2,3, Kebin Liu1,2,3 1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, 2Georgia Cancer Center, Augusta University, 3Charlie Norwood VA Medical Center JoVE 54040 Medicine Experimental Metastasis and CTL Adoptive Transfer Immunotherapy Mouse Model JoVE 2077 Immunology and Infection
En ortotopiske Mouse Model of Spontan Breast Cancer Metastase Amy V. Paschall1,2,3, Kebin Liu1,2,3 1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, 2Georgia Cancer Center, Augusta University, 3Charlie Norwood VA Medical Center JoVE 54040 Medicine
Experimental Metastasis and CTL Adoptive Transfer Immunotherapy Mouse Model JoVE 2077 Immunology and Infection