Keith E. Shearwin

Publications

• A Quantitative Binding Model for the Apl Protein, the Dual Purpose Recombination-directionality Factor and Lysis-lysogeny Regulator of Bacteriophage 186
  Nucleic Acids Research. 09, 2020  |   Pubmed ID: 32789491
• Combining Random Microseed Matrix Screening and the Magic Triangle for the Efficient Structure Solution of a Potential Lysin from Bacteriophage P68
  Acta Crystallographica. Section D, Structural Biology. Jul, 2019  |   Pubmed ID: 31282476
• RNA Polymerase Pausing at a Protein Roadblock Can Enhance Transcriptional Interference by Promoter Occlusion
  FEBS Letters. 05, 2019  |   Pubmed ID: 30892685
• Positive and Negative Control of Enhancer-Promoter Interactions by Other DNA Loops Generates Specificity and Tunability
  Cell Reports. 02, 2019  |   Pubmed ID: 30811991
• Characterizing Transcriptional Interference Between Converging Genes in Bacteria
  ACS Synthetic Biology. 03, 2019  |   Pubmed ID: 30717589
• Programmable DNA Looping Using Engineered Bivalent DCas9 Complexes
  Nature Communications. 11, 2017  |   Pubmed ID: 29158476
• Hidden Secrets of Sigma54 Promoters Revealed
  Trends in Biochemical Sciences. 12, 2017  |   Pubmed ID: 29126750
• Clonetegration Using OSIP Plasmids: One-Step DNA Assembly and Site-Specific Genomic Integration in Bacteria
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 27671938
• Aspects of Protein-DNA Interactions: a Review of Quantitative Thermodynamic Theory for Modelling Synthetic Circuits Utilising LacI and CI Repressors, IPTG and the Reporter Gene LacZ
  Biophysical Reviews. Dec, 2016  |   Pubmed ID: 28510022
• The Role of Repressor Kinetics in Relief of Transcriptional Interference Between Convergent Promoters
  Nucleic Acids Research. 08, 2016  |   Pubmed ID: 27378773
• Promoter Activation by CII, a Potent Transcriptional Activator from Bacteriophage 186
  The Journal of Biological Chemistry. Nov, 2014  |   Pubmed ID: 25294872
• Road Rules for Traffic on DNA-systematic Analysis of Transcriptional Roadblocking in Vivo
  Nucleic Acids Research. Aug, 2014  |   Pubmed ID: 25034688
• The Helix-turn-helix Motif of the Coliphage 186 Immunity Repressor Binds to Two Distinct Recognition Sequences
  The Journal of Biological Chemistry. Feb, 2002  |   Pubmed ID: 11700308
• Establishment of Lysogeny in Bacteriophage 186. DNA Binding and Transcriptional Activation by the CII Protein
  The Journal of Biological Chemistry. Sep, 2000  |   Pubmed ID: 10871623