Ki-Hyuk Shin The Shapiro Family Laboratory of Viral Oncology and Aging Research The UCLA School of Dentistry Biography Publications Institution JoVE Articles Ki-Hyuk Shin has not added a biography. If you are Ki-Hyuk Shin and would like to personalize this page please email our Author Liaison for assistance. Publications Zinc Up-Regulates Insulin Secretion from β Cell-Like Cells Derived from Stem Cells from Human Exfoliated Deciduous Tooth (SHED) International Journal of Molecular Sciences. Dec, 2016 | Pubmed ID: 27983594 Preexisting Periapical Inflammatory Condition Exacerbates Tooth Extraction-induced Bisphosphonate-related Osteonecrosis Of the Jaw Lesions in Mice Journal of Endodontics. Nov, 2016 | Pubmed ID: 27637460 IL-36 Induces Bisphosphonate-Related Osteonecrosis of the Jaw-Like Lesions in Mice by Inhibiting TGF-β-Mediated Collagen Expression Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2016 | Pubmed ID: 27567012 Orai1 Promotes Tumor Progression by Enhancing Cancer Stemness Via NFAT Signaling in Oral/oropharyngeal Squamous Cell Carcinoma Oncotarget. Jul, 2016 | Pubmed ID: 27259269 Orai1 Mediates Osteogenic Differentiation Via BMP Signaling Pathway in Bone Marrow Mesenchymal Stem Cells Biochemical and Biophysical Research Communications. May, 2016 | Pubmed ID: 27086849 Grainyhead-like 2 Regulates Epithelial Plasticity and Stemness in Oral Cancer Cells Carcinogenesis. May, 2016 | Pubmed ID: 26933170 Elevated Expression of JMJD6 is Associated with Oral Carcinogenesis and Maintains Cancer Stemness Properties Carcinogenesis. Feb, 2016 | Pubmed ID: 26645717 Human Papillomavirus 16 (HPV16) Enhances Tumor Growth and Cancer Stemness of HPV-negative Oral/oropharyngeal Squamous Cell Carcinoma Cells Via MiR-181 Regulation Papillomavirus Research (Amsterdam, Netherlands). Dec, 2015 | Pubmed ID: 26693182 Regulation of P53 During Senescence in Normal Human Keratinocytes Aging Cell. Oct, 2015 | Pubmed ID: 26138448 The P63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) Through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes The Journal of Biological Chemistry. Aug, 2015 | Pubmed ID: 26085095 Osteo-/odontogenic Differentiation of Induced Mesenchymal Stem Cells Generated Through Epithelial-mesenchyme Transition of Cultured Human Keratinocytes Journal of Endodontics. Nov, 2014 | Pubmed ID: 25201509 Impaired Bone Resorption and Woven Bone Formation Are Associated with Development of Osteonecrosis of the Jaw-like Lesions by Bisphosphonate and Anti-receptor Activator of NF-κB Ligand Antibody in Mice The American Journal of Pathology. Nov, 2014 | Pubmed ID: 25173134 Development of Oral Osteomucosal Tissue Constructs in Vitro and Localization of Fluorescently-labeled Bisphosphonates to Hard and Soft Tissue International Journal of Molecular Medicine. Aug, 2014 | Pubmed ID: 24920042 2-Hydroxyethyl Methacrylate Inhibits Migration of Dental Pulp Stem Cells Journal of Endodontics. Sep, 2013 | Pubmed ID: 23953290 Efavirenz Induces Autophagy and Aberrant Differentiation in Normal Human Keratinocytes International Journal of Molecular Medicine. Jun, 2013 | Pubmed ID: 23563240 Camphorquinone Inhibits Odontogenic Differentiation of Dental Pulp Cells and Triggers Release of Inflammatory Cytokines Journal of Endodontics. Jan, 2013 | Pubmed ID: 23228258 TNFα Enhances Cancer Stem Cell-like Phenotype Via Notch-Hes1 Activation in Oral Squamous Cell Carcinoma Cells Biochemical and Biophysical Research Communications. Jul, 2012 | Pubmed ID: 22728043 DeltaNp63α Protein Triggers Epithelial-mesenchymal Transition and Confers Stem Cell Properties in Normal Human Keratinocytes The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21880709 Expression and Mutation Analysis of Heterogeneous Nuclear Ribonucleoprotein G in Human Oral Cancer Oral Oncology. Nov, 2011 | Pubmed ID: 21840245 Identification of Senescence-inducing MicroRNAs in Normal Human Keratinocytes International Journal of Oncology. Nov, 2011 | Pubmed ID: 21725593 Radioprotective Effects of Bmi-1 Involve Epigenetic Silencing of Oxidase Genes and Enhanced DNA Repair in Normal Human Keratinocytes The Journal of Investigative Dermatology. Jun, 2011 | Pubmed ID: 21307872 MiR-181a Shows Tumor Suppressive Effect Against Oral Squamous Cell Carcinoma Cells by Downregulating K-ras Biochemical and Biophysical Research Communications. Jan, 2011 | Pubmed ID: 21167132 Grainyhead-like 2 Enhances the Human Telomerase Reverse Transcriptase Gene Expression by Inhibiting DNA Methylation at the 5'-CpG Island in Normal Human Keratinocytes The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20938050 Bmi-1 Extends the Life Span of Normal Human Oral Keratinocytes by Inhibiting the TGF-beta Signaling Experimental Cell Research. Oct, 2010 | Pubmed ID: 20630502 Association of Hsp90 to the HTERT Promoter is Necessary for HTERT Expression in Human Oral Cancer Cells Carcinogenesis. Dec, 2008 | Pubmed ID: 18820283 HIV-1 Tat Enhances Replicative Potential of Human Oral Keratinocytes Harboring HPV-16 Genome International Journal of Oncology. Oct, 2008 | Pubmed ID: 18813791 HnRNP G Elicits Tumor-suppressive Activity in Part by Upregulating the Expression of Txnip Biochemical and Biophysical Research Communications. Aug, 2008 | Pubmed ID: 18541147 Heterogeneous Nuclear Ribonucleoprotein G, Nitric Oxide, and Oral Carcinogenesis Nitric Oxide : Biology and Chemistry. Sep, 2008 | Pubmed ID: 18474262 P53 Promotes the Fidelity of DNA End-joining Activity By, in Part, Enhancing the Expression of Heterogeneous Nuclear Ribonucleoprotein G DNA Repair. Jun, 2007 | Pubmed ID: 17387044 Bmi-1 Cooperates with Human Papillomavirus Type 16 E6 to Immortalize Normal Human Oral Keratinocytes Experimental Cell Research. Feb, 2007 | Pubmed ID: 17161394 Heterogeneous Nuclear Ribonucleoprotein G Shows Tumor Suppressive Effect Against Oral Squamous Cell Carcinoma Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2006 | Pubmed ID: 16707624 Abnormal DNA End-joining Activity in Human Head and Neck Cancer International Journal of Molecular Medicine. May, 2006 | Pubmed ID: 16596281 HPV-16 E6 Oncoprotein Impairs the Fidelity of DNA End-joining Via P53-dependent and -independent Pathways International Journal of Oncology. Jan, 2006 | Pubmed ID: 16327998 Senescence-associated Decline in the Intranuclear Accumulation of HOGG1-alpha and Impaired 8-oxo-dG Repair Activity in Senescing Normal Human Oral Keratinocytes in Vivo Experimental Cell Research. Oct, 2005 | Pubmed ID: 16122734 Normal Human Oral Keratinocytes Demonstrate Abnormal DNA End Joining Activity During Replicative Senescence Mechanisms of Ageing and Development. Apr, 2005 | Pubmed ID: 15722106 Senescence Occurs with HTERT Repression and Limited Telomere Shortening in Human Oral Keratinocytes Cultured with Feeder Cells Journal of Cellular Physiology. Jun, 2004 | Pubmed ID: 15095283 Introduction of Human Telomerase Reverse Transcriptase to Normal Human Fibroblasts Enhances DNA Repair Capacity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2004 | Pubmed ID: 15073136 Microsatellite Instability and Mutations in DNA Mismatch Repair Genes in Sporadic Colorectal Cancers Diseases of the Colon and Rectum. Aug, 2003 | Pubmed ID: 12907901 Senescence-associated Genes in Normal Human Oral Keratinocytes Experimental Cell Research. Jul, 2003 | Pubmed ID: 12837283 Absence of HamTERT Gene Expression is Associated with Promoter Hypermethylation in Immortal Hamster Buccal Pouch Epithelial Cells International Journal of Oncology. Jun, 2003 | Pubmed ID: 12739004 Glutathione S-transferase M1 Associated with Cancer Occurrence in Korean HNPCC Families Carrying the HMLH1/hMSH2 Mutation Oncology Reports. Mar-Apr, 2003 | Pubmed ID: 12579293 Inactivation of the PTEN Gene by Mutation, Exonic Deletion, and Loss of Transcript in Human Oral Squamous Cell Carcinomas International Journal of Oncology. Nov, 2002 | Pubmed ID: 12370746 Prevalence of Microsatellite Instability, Inactivation of Mismatch Repair Genes, P53 Mutation, and Human Papillomavirus Infection in Korean Oral Cancer Patients International Journal of Oncology. Aug, 2002 | Pubmed ID: 12118324 Characterization of Novel Cell Lines Established from Three Human Oral Squamous Cell Carcinomas International Journal of Oncology. Jun, 2002 | Pubmed ID: 12011992 Mutational Analysis of Promoters of Mismatch Repair Genes HMSH2 and HMLH1 in Hereditary Nonpolyposis Colorectal Cancer and Early Onset Colorectal Cancer Patients: Identification of Three Novel Germ-line Mutations in Promoter of the HMSH2 Gene Cancer Research. Jan, 2002 | Pubmed ID: 11782355 Utvikling av en direkte Pulp-capping modell for evaluering av pulpal Wound Healing og reparerende Dentin Dannelse i Mus Minju Song1, Sol Kim1, Terresa Kim1, Sil Park1, Ki-Hyuk Shin1,2, Mo Kang1,2, No-Hee Park1,2,3, Reuben Kim1,2 1The Shapiro Family Laboratory of Viral Oncology and Aging Research, The UCLA School of Dentistry, 2UCLA Jonsson Comprehensive Cancer Center, 3David Geffen School of Medicine at UCLA JoVE 54973 Medicine
Utvikling av en direkte Pulp-capping modell for evaluering av pulpal Wound Healing og reparerende Dentin Dannelse i Mus Minju Song1, Sol Kim1, Terresa Kim1, Sil Park1, Ki-Hyuk Shin1,2, Mo Kang1,2, No-Hee Park1,2,3, Reuben Kim1,2 1The Shapiro Family Laboratory of Viral Oncology and Aging Research, The UCLA School of Dentistry, 2UCLA Jonsson Comprehensive Cancer Center, 3David Geffen School of Medicine at UCLA JoVE 54973 Medicine