Lars Edvinsson Department of Clinical Experimental Research Glostrup Research Institute, Rigshospitalet Biography Publications Institution JoVE Articles Lars Edvinsson has not added a biography. If you are Lars Edvinsson and would like to personalize this page please email our Author Liaison for assistance. Publications Myocardial Perfusion Recovery Induced by an α-calcitonin Gene-related Peptide Analogue Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. Jun, 2021 | Pubmed ID: 34089154 Identifying New Antimigraine Targets: Lessons from Molecular Biology Trends in Pharmacological Sciences. Apr, 2021 | Pubmed ID: 33495027 Oral Rimegepant for Migraine Prevention Lancet (London, England). 01, 2021 | Pubmed ID: 33338436 Transcriptome Profiling Revealed Early Vascular Smooth Muscle Cell Gene Activation Following Focal Ischemic Stroke in Female Rats - Comparisons with Males BMC Genomics. Dec, 2020 | Pubmed ID: 33297959 Estrogen Receptors α, β and GPER in the CNS and Trigeminal System - Molecular and Functional Aspects The Journal of Headache and Pain. Nov, 2020 | Pubmed ID: 33167864 Differences in Pituitary Adenylate Cyclase-activating Peptide and Calcitonin Gene-related Peptide Release in the Trigeminovascular System Cephalalgia : an International Journal of Headache. 10, 2020 | Pubmed ID: 32486909 Oxytocin As a Regulatory Neuropeptide in the Trigeminovascular System: Localization, Expression and Function of Oxytocin and Oxytocin Receptors Cephalalgia : an International Journal of Headache. 10, 2020 | Pubmed ID: 32486908 The Effects of CGRP in Vascular Tissue - Classical Vasodilation, Shadowed Effects and Systemic Dilemmas European Journal of Pharmacology. Aug, 2020 | Pubmed ID: 32442540 Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings: A Systematic Review and Meta-Analysis Headache. 06, 2020 | Pubmed ID: 32293721 Expression of the CGRP Family of Neuropeptides and Their Receptors in the Trigeminal Ganglion Journal of Molecular Neuroscience : MN. Jun, 2020 | Pubmed ID: 32086679 Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32079247 The Distribution of Oxytocin and the Oxytocin Receptor in Rat Brain: Relation to Regions Active in Migraine The Journal of Headache and Pain. Feb, 2020 | Pubmed ID: 32028899 Calcitonin Gene-Related Peptide (CGRP) and Cluster Headache Brain Sciences. Jan, 2020 | Pubmed ID: 31935868 Cellular Distribution of PACAP-38 and PACAP Receptors in the Rat Brain: Relation to Migraine Activated Regions Cephalalgia : an International Journal of Headache. 05, 2020 | Pubmed ID: 31810401 C-fibers May Modulate Adjacent Aδ-fibers Through Axon-axon CGRP Signaling at Nodes of Ranvier in the Trigeminal System The Journal of Headache and Pain. Nov, 2019 | Pubmed ID: 31718551 The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology Pharmacology. 2019 | Pubmed ID: 31484177 Rimegepant Oral Disintegrating Tablet for Migraine Lancet (London, England). 08, 2019 | Pubmed ID: 31311675 Does Inflammation Have a Role in Migraine? Nature Reviews. Neurology. 08, 2019 | Pubmed ID: 31263254 Board Walk - July 2019 Cephalalgia : an International Journal of Headache. 07, 2019 | Pubmed ID: 31246131 Role of CGRP in Migraine Handbook of Experimental Pharmacology. 2019 | Pubmed ID: 30725283 Vascular Pathology of Large Cerebral Arteries in Experimental Subarachnoid Hemorrhage: Vasoconstriction, Functional CGRP Depletion and Maintained CGRP Sensitivity European Journal of Pharmacology. Mar, 2019 | Pubmed ID: 30653947 MEK/ERK/1/2 Sensitive Vascular Changes Coincide with Retinal Functional Deficit, Following Transient Ophthalmic Artery Occlusion Experimental Eye Research. 02, 2019 | Pubmed ID: 30439349 CGRP Antibodies As Prophylaxis in Migraine Cell. 12, 2018 | Pubmed ID: 30550780 Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans Neuroscience. 11, 2018 | Pubmed ID: 30336190 CGRP As the Target of New Migraine Therapies - Successful Translation from Bench to Clinic Nature Reviews. Neurology. Jun, 2018 | Pubmed ID: 29691490 Vascular and Molecular Pharmacology of the Metabolically Stable CGRP Analogue, SAX European Journal of Pharmacology. Jun, 2018 | Pubmed ID: 29653090 PACAP and Its Role in Primary Headaches The Journal of Headache and Pain. Mar, 2018 | Pubmed ID: 29523978 Increased Endothelin-1-mediated Vasoconstriction After Organ Culture in Rat and Pig Ocular Arteries Can Be Suppressed with MEK/ERK1/2 Inhibitors Acta Ophthalmologica. Aug, 2018 | Pubmed ID: 29369532 Headache Advances in 2017: a New Horizon in Migraine Therapy The Lancet. Neurology. 01, 2018 | Pubmed ID: 29263007 Perivascular Neurotransmitters: Regulation of Cerebral Blood Flow and Role in Primary Headaches Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2017 | Pubmed ID: 29251523 Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats After Transient Middle Cerebral Artery Occlusion Neuroscience. Dec, 2017 | Pubmed ID: 29102661 A Novel Multicolor Flow-cytometry Application for Quantitative Detection of Receptors on Vascular Smooth Muscle Cells PloS One. 2017 | Pubmed ID: 29084284 Board Walk - October 2017 Cephalalgia : an International Journal of Headache. Oct, 2017 | Pubmed ID: 29039695 Recognizing the Role of CGRP and CGRP Receptors in Migraine and Its Treatment Cephalalgia : an International Journal of Headache. Jan, 2017 | Pubmed ID: 29020807 Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats PloS One. 2017 | Pubmed ID: 28880918 Distribution of CGRP and CGRP Receptor Components in the Rat Brain Cephalalgia : an International Journal of Headache. Jan, 2017 | Pubmed ID: 28856910 Distribution of CGRP and Its Receptor Components CLR and RAMP1 in the Rat Retina Experimental Eye Research. 08, 2017 | Pubmed ID: 28603014 Myocardial Ischemia-reperfusion Enhances Transcriptional Expression of Endothelin-1 and Vasoconstrictor ETB Receptors Via the Protein Kinase MEK-ERK1/2 Signaling Pathway in Rat PloS One. 2017 | Pubmed ID: 28323857 Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat Journal of Molecular Neuroscience : MN. Mar, 2017 | Pubmed ID: 27933490 Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage After Transient Global Cerebral Ischemia in Rat PloS One. 2016 | Pubmed ID: 27322388 Improved Assessment of Outcomes Following Transient Global Cerebral Ischemia in Mice Experimental Brain Research. 07, 2016 | Pubmed ID: 26914479 New Insights on Pyrimidine Signalling Within the Arterial Vasculature - Different Roles for P2Y2 and P2Y6 Receptors in Large and Small Coronary Arteries of the Mouse Journal of Molecular and Cellular Cardiology. 04, 2016 | Pubmed ID: 26827897 Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-Mediated Contractility Via Activation of Focal Adhesion Kinase and Extracellular Regulated Kinase 1/2 in Cerebral Arteries from Rat Basic & Clinical Pharmacology & Toxicology. Jul, 2016 | Pubmed ID: 26781487 Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco. May, 2016 | Pubmed ID: 26508395 Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries Basic & Clinical Pharmacology & Toxicology. Feb, 2016 | Pubmed ID: 26272341 Kynurenic Acid Modulates Experimentally Induced Inflammation in the Trigeminal Ganglion The Journal of Headache and Pain. 2015 | Pubmed ID: 26627709 Experimental Inflammation Following Dural Application of Complete Freund's Adjuvant or Inflammatory Soup Does Not Alter Brain and Trigeminal Microvascular Passage The Journal of Headache and Pain. 2015 | Pubmed ID: 26512021 CaMKII Inhibition with KN93 Attenuates Endothelin and Serotonin Receptor-mediated Vasoconstriction and Prevents Subarachnoid Hemorrhage-induced Deficits in Sensorimotor Function Journal of Neuroinflammation. Dec, 2014 | Pubmed ID: 25498987 CaMKII and MEK1/2 Inhibition Time-dependently Modify Inflammatory Signaling in Rat Cerebral Arteries During Organ Culture Journal of Neuroinflammation. May, 2014 | Pubmed ID: 24886705 Comparison of the Vasodilator Responses of Isolated Human and Rat Middle Meningeal Arteries to Migraine Related Compounds The Journal of Headache and Pain. Apr, 2014 | Pubmed ID: 24754925 Pre-chiasmatisk, enkelt injeksjon av autologt blod for å indusere eksperimentell subaraknoid blødning i en rottemodell Jesper Peter Bömers1,2, Sara Ellinor Johansson2, Lars Edvinsson2,4, Tiit Illimar Mathiesen1,3,5, Kristian Agmund Haanes2 1Department of Neurosurgery, Rigshospitalet, 2Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, 3Department of Clinical Medicine, University of Copenhagen, 4Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, 5Department of Clinical Neuroscience, Karolinska Institutet JoVE 62567 Neuroscience
Pre-chiasmatisk, enkelt injeksjon av autologt blod for å indusere eksperimentell subaraknoid blødning i en rottemodell Jesper Peter Bömers1,2, Sara Ellinor Johansson2, Lars Edvinsson2,4, Tiit Illimar Mathiesen1,3,5, Kristian Agmund Haanes2 1Department of Neurosurgery, Rigshospitalet, 2Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, 3Department of Clinical Medicine, University of Copenhagen, 4Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, 5Department of Clinical Neuroscience, Karolinska Institutet JoVE 62567 Neuroscience