Leela Shrestha Centre for Medicines Discovery, Nuffield Department of Medicine University of Oxford Biography Publications Institution JoVE Articles Leela Shrestha has not added a biography. If you are Leela Shrestha and would like to personalize this page please email our Author Liaison for assistance. Publications Molecular Basis for the Regulation of Human Glycogen Synthase by Phosphorylation and Glucose-6-phosphate Nature Structural & Molecular Biology. Jul, 2022 | Pubmed ID: 35835870 The Structural Basis of Fatty Acid Elongation by the ELOVL Elongases Nature Structural & Molecular Biology. Jun, 2021 | Pubmed ID: 34117479 A Lower X-gate in TASK Channels Traps Inhibitors Within the Vestibule Nature. Jun, 2020 | Pubmed ID: 32499642 The Structural Basis of Lipid Scrambling and Inactivation in the Endoplasmic Reticulum Scramblase TMEM16K Nature Communications. Sep, 2019 | Pubmed ID: 31477691 Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design Cell. Nov, 2018 | Pubmed ID: 30388443 Structure of the Polycystic Kidney Disease TRP Channel Polycystin-2 (PC2) Nature Structural & Molecular Biology. Feb, 2017 | Pubmed ID: 27991905 Molecular Basis of Classic Galactosemia from the Structure of Human Galactose 1-phosphate Uridylyltransferase Human Molecular Genetics. Jun, 2016 | Pubmed ID: 27005423 Crystal Structure of Porphyromonas Gingivalis Peptidylarginine Deiminase: Implications for Autoimmunity in Rheumatoid Arthritis Annals of the Rheumatic Diseases. Jun, 2016 | Pubmed ID: 26209657 Structures of ABCB10, a Human ATP-binding Cassette Transporter in Apo- and Nucleotide-bound States Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23716676 The Structural Basis of ZMPSTE24-dependent Laminopathies Science (New York, N.Y.). Mar, 2013 | Pubmed ID: 23539603 Expression and Purification of Human Solute Carrier Transporters Using Codon-Optimized Genes (Video) | JoVE Sagar Raturi1, Huanyu Li1, Yung-Ning Chang2, Andreea Scacioc1, Tina Bohstedt1, Alejandra Fernandez-Cid1, Adam Evans1, Patrizia Abrusci1, Abilasha Balakrishnan1, Tomas C. Pascoa1, Didi He1, Gamma Chi1, Nanki Kaur Singh1, Mingda Ye1, Anna Li1, Leela Shrestha1, Dong Wang1, Eleanor P. Williams1, Nicola A. Burgess-Brown1, Katharina L. Dürr1, Vera Puetter2, Alvaro Ingles-Prieto3, David B. Sauer1 1Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, 2Nuvisan ICB GmbH, 3CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences JoVE 65878 Biochemistry
Expression and Purification of Human Solute Carrier Transporters Using Codon-Optimized Genes (Video) | JoVE Sagar Raturi1, Huanyu Li1, Yung-Ning Chang2, Andreea Scacioc1, Tina Bohstedt1, Alejandra Fernandez-Cid1, Adam Evans1, Patrizia Abrusci1, Abilasha Balakrishnan1, Tomas C. Pascoa1, Didi He1, Gamma Chi1, Nanki Kaur Singh1, Mingda Ye1, Anna Li1, Leela Shrestha1, Dong Wang1, Eleanor P. Williams1, Nicola A. Burgess-Brown1, Katharina L. Dürr1, Vera Puetter2, Alvaro Ingles-Prieto3, David B. Sauer1 1Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, 2Nuvisan ICB GmbH, 3CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences JoVE 65878 Biochemistry