Leonard Moise Institute for Immunology and Informatics University of Rhode Island Biography Publications Institution JoVE Articles Leonard Moise has not added a biography. If you are Leonard Moise and would like to personalize this page please email our Author Liaison for assistance. Publications Immunization with Cross-conserved H1N1 Influenza CD4+ T-cell Epitopes Lowers Viral Burden in HLA DR3 Transgenic Mice Human Vaccines & Immunotherapeutics. Oct, 2013 | Pubmed ID: 24045788 Making Vaccines "on Demand": a Potential Solution for Emerging Pathogens and Biodefense? Human Vaccines & Immunotherapeutics. Sep, 2013 | Pubmed ID: 23877094 Universal H1N1 Influenza Vaccine Development: Identification of Consensus Class II Hemagglutinin and Neuraminidase Epitopes Derived from Strains Circulating Between 1980 and 2011 Human Vaccines & Immunotherapeutics. Jul, 2013 | Pubmed ID: 23846304 Low Immunogenicity Predicted for Emerging Avian-origin H7N9: Implication for Influenza Vaccine Design Human Vaccines & Immunotherapeutics. May, 2013 | Pubmed ID: 23807079 Building Better Biotherapeutics and Vaccines by Design: EpiVax, Inc., an Immunology Company Rhode Island Medical Journal (2013). 2013 | Pubmed ID: 23641421 Epitope Recognition in HLA-DR3 Transgenic Mice Immunized to TSH-R Protein or Peptides Endocrinology. Jun, 2013 | Pubmed ID: 23592747 The Two-faced T Cell Epitope: Examining the Host-microbe Interface with JanusMatrix Human Vaccines & Immunotherapeutics. Jul, 2013 | Pubmed ID: 23584251 In Vitro and in Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): a Promising New Tool for Tolerance Induction and Treatment of Autoimmunity Journal of Clinical Immunology. Jan, 2013 | Pubmed ID: 22941509 Moving Helicobacter Pylori Vaccine Development Forward with Bioinformatics and Immunomics Expert Review of Vaccines. Sep, 2012 | Pubmed ID: 23151160 Of [Hamsters] and Men: a New Perspective on Host Cell Proteins Human Vaccines & Immunotherapeutics. Sep, 2012 | Pubmed ID: 23124469 Conservation of HIV-1 T Cell Epitopes Across Time and Clades: Validation of Immunogenic HLA-A2 Epitopes Selected for the GAIA HIV Vaccine Vaccine. Dec, 2012 | Pubmed ID: 23102976 Design and Analysis of Immune-evading Enzymes for ADEPT Therapy Protein Engineering, Design & Selection : PEDS. Oct, 2012 | Pubmed ID: 22898588 Effect of HLA DR Epitope De-immunization of Factor VIII in Vitro and in Vivo Clinical Immunology (Orlando, Fla.). Mar, 2012 | Pubmed ID: 22222093 Harnessing the Power of Genomics and Immunoinformatics to Produce Improved Vaccines Expert Opinion on Drug Discovery. Jan, 2011 | Pubmed ID: 22646824 H. Pylori Vaccines: Why We Still Don't Have Any Human Vaccines. Nov, 2011 | Pubmed ID: 22048119 HelicoVax: Epitope-based Therapeutic Helicobacter Pylori Vaccination in a Mouse Model Vaccine. Mar, 2011 | Pubmed ID: 21236233 VennVax, a DNA-prime, Peptide-boost Multi-T-cell Epitope Poxvirus Vaccine, Induces Protective Immunity Against Vaccinia Infection by T Cell Response Alone Vaccine. Jan, 2011 | Pubmed ID: 21055490 A Method for Individualizing the Prediction of Immunogenicity of Protein Vaccines and Biologic Therapeutics: Individualized T Cell Epitope Measure (iTEM) Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20706613 K(V)4.2 Channels Tagged in the S1-S2 Loop for Alpha-bungarotoxin Binding Provide a New Tool for Studies of Channel Expression and Localization Channels (Austin, Tex.). Mar-Apr, 2010 | Pubmed ID: 20139708 Immunoinformatic Comparison of T-cell Epitopes Contained in Novel Swine-origin Influenza A (H1N1) Virus with Epitopes in 2008-2009 Conventional Influenza Vaccine Vaccine. Sep, 2009 | Pubmed ID: 19660593 Epitope-based Vaccination Against Pneumonic Tularemia Vaccine. Aug, 2009 | Pubmed ID: 19616492 In Silico-accelerated Identification of Conserved and Immunogenic Variola/vaccinia T-cell Epitopes Vaccine. Oct, 2009 | Pubmed ID: 19559119 Activation of Natural Regulatory T Cells by IgG Fc-derived Peptide "Tregitopes" Blood. Oct, 2008 | Pubmed ID: 18660382 Identification of Genome-derived Vaccine Candidates Conserved Between Human and Mouse-adapted Strains of H. Pylori Human Vaccines. May-Jun, 2008 | Pubmed ID: 18376134 Tularemia Vaccines - an Overview Medicine and Health, Rhode Island. Oct, 2007 | Pubmed ID: 18019188 Progress Towards a Genome-derived, Epitope-driven Vaccine for Latent TB Infection Medicine and Health, Rhode Island. Oct, 2007 | Pubmed ID: 18019185 Vaccine Renaissance--from Basic Research to Implementation Medicine and Health, Rhode Island. Oct, 2007 | Pubmed ID: 18019184 Analysis of ChimeriVax Japanese Encephalitis Virus Envelope for T-cell Epitopes and Comparison to Circulating Strain Sequences Vaccine. Nov, 2007 | Pubmed ID: 17942198 Prediction of Immunogenicity for Therapeutic Proteins: State of the Art Current Opinion in Drug Discovery & Development. May, 2007 | Pubmed ID: 17554860 New Tools, New Approaches and New Ideas for Vaccine Development Expert Review of Vaccines. Apr, 2007 | Pubmed ID: 17408360 Diversity of Francisella Tularensis Schu4 Antigens Recognized by T Lymphocytes After Natural Infections in Humans: Identification of Candidate Epitopes for Inclusion in a Rationally Designed Tularemia Vaccine Vaccine. Apr, 2007 | Pubmed ID: 17291638 Evolutionary Deimmunization: an Ancillary Mechanism for Self-tolerance? Cellular Immunology. Dec, 2006 | Pubmed ID: 17445787 Putting Immunoinformatics to the Test Nature Biotechnology. Jul, 2006 | Pubmed ID: 16841062 NMR Structural Analysis of Alpha-bungarotoxin and Its Complex with the Principal Alpha-neurotoxin-binding Sequence on the Alpha 7 Subunit of a Neuronal Nicotinic Acetylcholine Receptor The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11790782 A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes Regina Salvat1, Leonard Moise2, Chris Bailey-Kellogg3, Karl E. Griswold1 1Thayer School of Engineering, Dartmouth College, 2Institute for Immunology and Informatics, University of Rhode Island, 3Department of Computer Science, Dartmouth College JoVE 51308 Biology
A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes Regina Salvat1, Leonard Moise2, Chris Bailey-Kellogg3, Karl E. Griswold1 1Thayer School of Engineering, Dartmouth College, 2Institute for Immunology and Informatics, University of Rhode Island, 3Department of Computer Science, Dartmouth College JoVE 51308 Biology