Lesley Ann Sutton Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala University Biography Publications Institution JoVE Articles Lesley Ann Sutton has not added a biography. If you are Lesley Ann Sutton and would like to personalize this page please email our Author Liaison for assistance. Publications Automated Shape-based Clustering of 3D Immunoglobulin Protein Structures in Chronic Lymphocytic Leukemia BMC Bioinformatics. Nov, 2018 | Pubmed ID: 30453883 Tailored Approaches Grounded on Immunogenetic Features for Refined Prognostication in Chronic Lymphocytic Leukemia Haematologica. Sep, 2018 | Pubmed ID: 30262567 Highly Similar Genomic Landscapes in Monoclonal B-cell Lymphocytosis and Ultra-stable Chronic Lymphocytic Leukemia with Low Frequency of Driver Mutations Haematologica. May, 2018 | Pubmed ID: 29449433 No Improvement in Long-term Survival over Time for Chronic Lymphocytic Leukemia Patients in Stereotyped Subsets #1 and #2 Treated with Chemo(immuno)therapy Haematologica. Apr, 2018 | Pubmed ID: 29269523 Immunoglobulin Genes in Chronic Lymphocytic Leukemia: Key to Understanding the Disease and Improving Risk Stratification Haematologica. 06, 2017 | Pubmed ID: 28566340 Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2017 | Pubmed ID: 28536306 Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence The American Journal of Pathology. Jul, 2017 | Pubmed ID: 28457696 Massive and Parallel Expression Profiling Using Microarrayed Single-cell Sequencing Nature Communications. 10, 2016 | Pubmed ID: 27739429 ATM Mutations in Major Stereotyped Subsets of Chronic Lymphocytic Leukemia: Enrichment in Subset #2 is Associated with Markedly Short Telomeres Haematologica. 09, 2016 | Pubmed ID: 27479817 Different Spectra of Recurrent Gene Mutations in Subsets of Chronic Lymphocytic Leukemia Harboring Stereotyped B-cell Receptors Haematologica. 08, 2016 | Pubmed ID: 27198719 The Histone Methyltransferase EZH2 As a Novel Prosurvival Factor in Clinically Aggressive Chronic Lymphocytic Leukemia Oncotarget. Jun, 2016 | Pubmed ID: 27191993 Not All Subclones Matter in CLL Blood. 04, 2016 | Pubmed ID: 27127300 Additional Trisomies Amongst Patients with Chronic Lymphocytic Leukemia Carrying Trisomy 12: the Accompanying Chromosome Makes a Difference Haematologica. 07, 2016 | Pubmed ID: 27102498 Innovation in the Prognostication of Chronic Lymphocytic Leukemia: How Far Beyond TP53 Gene Analysis Can We Go? Haematologica. Mar, 2016 | Pubmed ID: 26928246 Whole-exome Sequencing in Relapsing Chronic Lymphocytic Leukemia: Clinical Impact of Recurrent RPS15 Mutations Blood. Feb, 2016 | Pubmed ID: 26675346 An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2016 | Pubmed ID: 26647217 UGT2B17 Expression: a Novel Prognostic Marker Within IGHV-mutated Chronic Lymphocytic Leukemia? Haematologica. Feb, 2016 | Pubmed ID: 26589911 Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2016 | Pubmed ID: 26338994 Prognostic Relevance of MYD88 Mutations in CLL: the Jury is Still Out Blood. Aug, 2015 | Pubmed ID: 26294719 ARResT/AssignSubsets: a Novel Application for Robust Subclassification of Chronic Lymphocytic Leukemia Based on B Cell Receptor IG Stereotypy Bioinformatics (Oxford, England). Dec, 2015 | Pubmed ID: 26249808 Functional Loss of IκBε Leads to NF-κB Deregulation in Aggressive Chronic Lymphocytic Leukemia The Journal of Experimental Medicine. Jun, 2015 | Pubmed ID: 25987724 The Complex Interplay Between Cell-intrinsic and Cell-extrinsic Factors Driving the Evolution of Chronic Lymphocytic Leukemia Seminars in Cancer Biology. Oct, 2015 | Pubmed ID: 25963298 Molecular Evidence for Antigen Drive in the Natural History of Mantle Cell Lymphoma The American Journal of Pathology. Jun, 2015 | Pubmed ID: 25843681 Not All IGHV3-21 Chronic Lymphocytic Leukemias Are Equal: Prognostic Considerations Blood. Jan, 2015 | Pubmed ID: 25634617 Deciphering the Molecular Landscape in Chronic Lymphocytic Leukemia: Time Frame of Disease Evolution Haematologica. Jan, 2015 | Pubmed ID: 25552678 An Entity Evolving into a Community: Defining the Common Ancestor and Evolutionary Trajectory of Chronic Lymphocytic Leukemia Stereotyped Subset #4 Molecular Medicine (Cambridge, Mass.). Apr, 2015 | Pubmed ID: 25486132 Targeted Next-generation Sequencing in Chronic Lymphocytic Leukemia: a High-throughput Yet Tailored Approach Will Facilitate Implementation in a Clinical Setting Haematologica. Mar, 2015 | Pubmed ID: 25480502 Clonal Evolution in Chronic Lymphocytic Leukemia: Impact of Subclonality on Disease Progression Expert Review of Hematology. Feb, 2015 | Pubmed ID: 25345442 Clinical Effect of Stereotyped B-cell Receptor Immunoglobulins in Chronic Lymphocytic Leukaemia: a Retrospective Multicentre Study The Lancet. Haematology. Nov, 2014 | Pubmed ID: 27030157 Immunogenetic Studies of Chronic Lymphocytic Leukemia: Revelations and Speculations About Ontogeny and Clinical Evolution Cancer Research. Aug, 2014 | Pubmed ID: 25074616 Lymphoma Development in Patients with Autoimmune and Inflammatory Disorders--what Are the Driving Forces? Seminars in Cancer Biology. Feb, 2014 | Pubmed ID: 24333759 IgG-switched CLL Has a Distinct Immunogenetic Signature from the Common MD Variant: Ontogenetic Implications Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2014 | Pubmed ID: 24240110 In Situ Protein Detection for Companion Diagnostics Frontiers in Oncology. Oct, 2013 | Pubmed ID: 24199171 A Key Role for EZH2 in Epigenetic Silencing of HOX Genes in Mantle Cell Lymphoma Epigenetics. Dec, 2013 | Pubmed ID: 24107828 Antigen Selection in B-cell Lymphomas--tracing the Evidence Seminars in Cancer Biology. Dec, 2013 | Pubmed ID: 23932942 Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence Molecular Medicine (Cambridge, Mass.). Aug, 2013 | Pubmed ID: 23922244 Next Generation RNA-sequencing in Prognostic Subsets of Chronic Lymphocytic Leukemia American Journal of Hematology. Jul, 2012 | Pubmed ID: 22674506 IGHV3-21 Gene Frequency in a Swedish Cohort of Patients with Newly Diagnosed Chronic Lymphocytic Leukemia Clinical Lymphoma, Myeloma & Leukemia. Jun, 2012 | Pubmed ID: 22464020 Extensive Intraclonal Diversification in a Subgroup of Chronic Lymphocytic Leukemia Patients with Stereotyped IGHV4-34 Receptors: Implications for Ongoing Interactions with Antigen Blood. Nov, 2009 | Pubmed ID: 19713457 Immunglobulin-gen Sekvensanalyse i kronisk lymfatisk leukæmi: Fra Patient materiale til sekvens fortolkning Andreas Agathangelidis*1, Lesley Ann Sutton*2,3, Anastasia Hadzidimitriou1, Cristina Tresoldi4, Anton W. Langerak5, Chrysoula Belessi6, Frederic Davi7, Richard Rosenquist2,3, Kostas Stamatopoulos1,2, Paolo Ghia8 1Institute of Applied Biosciences, Centre for Research and Technology Hellas, 2Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 3Department of Molecular Medicine and Surgery, Karolinska Institutet, 4Division of Immunology, Transplantation and Infectious, IRCCS San Raffaele Scientific Institute, 5Department of Immunology, Laboratory for Medical Immunology, Erasmus University Medical Center, 6Hematology Department, Nikea General Hospital, 7Assistance publique - Hôpitaux de Paris (AP-HP), Hopital Pitié-Salpêtrière, Department of Hematology, and UPMC University Paris 06, UMRS 1138, 8Division of Experimental Oncology, IRCCS Istituto Scientifico San Raffaele and Università Vita-Salute San Raffaele JoVE 57787 Cancer Research
Immunglobulin-gen Sekvensanalyse i kronisk lymfatisk leukæmi: Fra Patient materiale til sekvens fortolkning Andreas Agathangelidis*1, Lesley Ann Sutton*2,3, Anastasia Hadzidimitriou1, Cristina Tresoldi4, Anton W. Langerak5, Chrysoula Belessi6, Frederic Davi7, Richard Rosenquist2,3, Kostas Stamatopoulos1,2, Paolo Ghia8 1Institute of Applied Biosciences, Centre for Research and Technology Hellas, 2Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 3Department of Molecular Medicine and Surgery, Karolinska Institutet, 4Division of Immunology, Transplantation and Infectious, IRCCS San Raffaele Scientific Institute, 5Department of Immunology, Laboratory for Medical Immunology, Erasmus University Medical Center, 6Hematology Department, Nikea General Hospital, 7Assistance publique - Hôpitaux de Paris (AP-HP), Hopital Pitié-Salpêtrière, Department of Hematology, and UPMC University Paris 06, UMRS 1138, 8Division of Experimental Oncology, IRCCS Istituto Scientifico San Raffaele and Università Vita-Salute San Raffaele JoVE 57787 Cancer Research