Li Zhu Cyrus Tang Hematology Center, Cyrus Tang Medical Institute Soochow University Biography Publications Institution JoVE Articles Li Zhu has not added a biography. If you are Li Zhu and would like to personalize this page please email our Author Liaison for assistance. Publications Histological Features of Chronic Hepatitis B Patients with Normal Alanine Aminotransferase According to Different Criteria Hepatology Communications. Jan, 2024 | Pubmed ID: 38206209 Liver Inflammation Activity in Patients with Autoimmune Hepatitis with Normal Alanine Aminotransferase and Immunoglobulin G Levels Journal of Translational Autoimmunity. Jun, 2024 | Pubmed ID: 38188039 NAFLD is Associated with Less Severe Liver Fibrosis in Chronic Hepatitis B: A Multi-center, Retrospective Study Annals of Hepatology. 2024 | Pubmed ID: 37742745 The Chromatin Remodeling Protein BRG1 Regulates HSC-myofibroblast Differentiation and Liver Fibrosis Cell Death & Disease. Dec, 2023 | Pubmed ID: 38092723 Noninvasive Diagnosis of Significant Liver Inflammation in Patients with Chronic Hepatitis B in the Indeterminate Phase Virulence. Dec, 2023 | Pubmed ID: 37938933 A Novel Web-based Online Nomogram to Predict Advanced Liver Fibrosis in Patients with Autoimmune Hepatitis-primary Biliary Cholangitis Overlap Syndrome Journal of Translational Autoimmunity. Dec, 2023 | Pubmed ID: 37877134 Corrigendum to "Sema7A Protects Against High-fat Diet-induced Obesity and Hepatic Steatosis by Regulating Adipo/lipogenesis" [Mol Metab. 70 (2023) 101698]∗ Molecular Metabolism. Dec, 2023 | Pubmed ID: 37871636 Functional Diversification and Dynamics of CAR-T Cells in Patients with B-ALL Cell Reports. Oct, 2023 | Pubmed ID: 37851569 Development and Validation of a Nomogram to Predict Significant Liver Inflammation in Patients with Chronic Hepatitis B Infection and Drug Resistance. 2023 | Pubmed ID: 37576516 Develop and Validate a Novel Online AIHI-nomogram to Predict Severe Liver Inflammation in Patients with Autoimmune Hepatitis Annals of Hepatology. Jul, 2023 | Pubmed ID: 37442347 Differential Regulation of JAK1 Expression by ETS1 Associated with Predisposition to Primary Biliary Cholangitis Journal of Genetics and Genomics = Yi Chuan Xue Bao. Jun, 2023 | Pubmed ID: 37348755 Endothelial CCRL2 Induced by Disturbed Flow Promotes Atherosclerosis Via Chemerin-dependent β2 Integrin Activation in Monocytes Cardiovascular Research. Aug, 2023 | Pubmed ID: 37279540 An Easy-to-use AIHF-nomogram to Predict Advanced Liver Fibrosis in Patients with Autoimmune Hepatitis Frontiers in Immunology. 2023 | Pubmed ID: 37266419 The Role of Blood Flow in Vessel Remodeling and Its Regulatory Mechanism During Developmental Angiogenesis Cellular and Molecular Life Sciences : CMLS. May, 2023 | Pubmed ID: 37221410 -methyladenosine Modification Contributes to Respiratory Syncytial Virus Infection Heliyon. Apr, 2023 | Pubmed ID: 37089388 Ubiquitin E3 Ligase β-TrCP Negatively Regulates Surface Protein of Hepatitis B Virus Journal of Medical Virology. Mar, 2023 | Pubmed ID: 36846904 Sema7A Protects Against High-fat Diet-induced Obesity and Hepatic Steatosis by Regulating Adipo/lipogenesis Molecular Metabolism. Apr, 2023 | Pubmed ID: 36842496 Significant Histological Disease of Patients with Chronic Hepatitis B Virus Infection in the Grey Zone Alimentary Pharmacology & Therapeutics. Mar, 2023 | Pubmed ID: 36324235 Chinese Guideline on Allergen Immunotherapy for Allergic Rhinitis: The 2022 Update Allergy, Asthma & Immunology Research. Nov, 2022 | Pubmed ID: 36426395 Analysis of M6A-related Signatures Associated with the Tumor Immune Microenvironment and Predict Survival in Acute Myeloid Leukemia Annals of Translational Medicine. Aug, 2022 | Pubmed ID: 36111007 GRK2 Regulates ADP Signaling in Platelets Via P2Y1 and P2Y12 Blood Advances. Aug, 2022 | Pubmed ID: 35793439 Clinical Features and Prognosis of COVID-19 Patients with Metabolic Syndrome: A Multicenter, Retrospective Study Medicina Clinica (English Ed.). May, 2022 | Pubmed ID: 35702719 Nurse-led Cancer Palliative Care Compared to Oncologist-led Cancer Palliative Care: A Retrospective Analysis of Chinese Patients Suffering from Cancer and Receiving Chemotherapy Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University. Oct, 2022 | Pubmed ID: 35666054 Single-cell Transcriptional Profiling of Human Carotid Plaques Reveals a Subpopulation of Endothelial Cells Associated with Stroke Incidences Journal of Cellular and Molecular Medicine. Jun, 2022 | Pubmed ID: 35527426 Significance of T-Cell Subsets for Clinical Response to Peginterferon Alfa-2a Therapy in HBeAg-Positive Chronic Hepatitis B Patients International Journal of General Medicine. 2022 | Pubmed ID: 35509606 Role of Semaphorins in Ischemic Stroke Frontiers in Molecular Neuroscience. 2022 | Pubmed ID: 35350431 Caspase-3/Treg and PI3K/AKT/mTOR Pathway is Involved in Liver Ischemia Reperfusion Injury (IRI) Protection by Everolimus Transplant Immunology. Apr, 2022 | Pubmed ID: 35093505 Clinical Features and Prognosis of COVID-19 Patients with Metabolic Syndrome: A Multicenter, Retrospective Study Medicina Clinica. May, 2022 | Pubmed ID: 34243955 Clinical Features and Outcomes of Patients with COVID-19 After Discharge: A Retrospective, Multi-center Study Discovery Medicine. 2021 | Pubmed ID: 35219355 CircCRIM1 Promotes Hepatocellular Carcinoma Proliferation and Angiogenesis by Sponging MiR-378a-3p and Regulating SKP2 Expression Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 34869393 CLEC-2-dependent Platelet Subendothelial Accumulation by Flow Disturbance Contributes to Atherogenesis in Mice Theranostics. 2021 | Pubmed ID: 34815786 Single-cell RNA-seq Reveals Cellular Heterogeneity of Mouse Carotid Artery Under Disturbed Flow Cell Death Discovery. Jul, 2021 | Pubmed ID: 34282126 Clinical and Virological Course of Patients with Coronavirus Disease 2019 in Jiangsu Province, China: a Retrospective, Multi-center Cohort Study Virology Journal. Jul, 2021 | Pubmed ID: 34261488 Risk of Severe Illness of COVID-19 Patients with NAFLD and Increased NAFLD Fibrosis Scores Journal of Clinical Laboratory Analysis. Aug, 2021 | Pubmed ID: 34213039 Acid-sensing Ion Channel 1 (ASIC1) Mediates Weak Acid-induced Migration of Human Malignant Glioma Cells American Journal of Cancer Research. 2021 | Pubmed ID: 33791169 Ubiquitin E3 Ligase MID1 Inhibits the Innate Immune Response by Ubiquitinating IRF3 Immunology. Jul, 2021 | Pubmed ID: 33513265 A Novel Regulatory Loop MiR-101/ANXA2/EGR1 Mediates Malignant Characteristics of Liver Cancer Stem Cells Carcinogenesis. Feb, 2021 | Pubmed ID: 32531042 Ubiquitin E3 Ligase C-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1 Frontiers in Microbiology. 2020 | Pubmed ID: 33329486 Risk Factors of Liver Injury in Patients with Coronavirus Disease 2019 in Jiangsu, China: A Retrospective, Multi-center Study Journal of Medical Virology. Nov, 2020 | Pubmed ID: 33174624 Molecular Docking-assisted Screening Reveals Tannic Acid As a Natural Protein Disulphide Isomerase Inhibitor with Antiplatelet and Antithrombotic Activities Journal of Cellular and Molecular Medicine. Dec, 2020 | Pubmed ID: 33128352 Lipid Peroxidation Aggravates Anti-tuberculosis Drug-induced Liver Injury: Evidence of Ferroptosis Induction Biochemical and Biophysical Research Communications. Dec, 2020 | Pubmed ID: 33121683 Low Dose IL-2 Suppress Osteoclastogenesis in Collagen-induced Arthritis Via JNK Dependent Pathway Immunity, Inflammation and Disease. Dec, 2020 | Pubmed ID: 33098626 Corticosteroid Therapy is Associated with the Delay of SARS-CoV-2 Clearance in COVID-19 Patients European Journal of Pharmacology. Dec, 2020 | Pubmed ID: 32941927 FLAIR Vascular Hyperintensity: an Unfavorable Marker of Early Neurological Deterioration and Short-term Prognosis in Acute Ischemic Stroke Patients Annals of Palliative Medicine. Sep, 2020 | Pubmed ID: 32921100 Clinical Features of COVID-19 Patients with Non-alcoholic Fatty Liver Disease Hepatology Communications. Aug, 2020 | Pubmed ID: 32838108 Semaphorin 7A Promotes Endothelial to Mesenchymal Transition Through ATF3 Mediated TGF-β2/Smad Signaling Cell Death & Disease. Aug, 2020 | Pubmed ID: 32826874 The Role of Semaphorins in Metabolic Disorders International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32781674 Overweight and Obesity Are Risk Factors of Severe Illness in Patients with COVID-19 Obesity (Silver Spring, Md.). 11, 2020 | Pubmed ID: 32735706 A Case Series of COVID-19 Patients with Chronic Hepatitis B Virus Infection Journal of Medical Virology. Nov, 2020 | Pubmed ID: 32558945 Clinical Findings of Patients with Coronavirus Disease 2019 in Jiangsu Province, China: A retrospective, Multi-center Study PLoS Neglected Tropical Diseases. 05, 2020 | Pubmed ID: 32384078 Epidemiological and Clinical Features of Asymptomatic Patients with SARS-CoV-2 Infection Journal of Medical Virology. Oct, 2020 | Pubmed ID: 32346873 Clinical Characteristics of a Case Series of Children with Coronavirus Disease 2019 Pediatric Pulmonology. Jun, 2020 | Pubmed ID: 32270592 Humanin Analogue, HNG, Inhibits Platelet Activation and Thrombus Formation by Stabilizing Platelet Microtubules Journal of Cellular and Molecular Medicine. Apr, 2020 | Pubmed ID: 32174022 USP12 Translocation Maintains Interferon Antiviral Efficacy by Inhibiting CBP Acetyltransferase Activity PLoS Pathogens. Jan, 2020 | Pubmed ID: 31899788 Plasma Soluble C-type Lectin-like Receptor-2 is Associated with the Risk of Coronary Artery Disease Frontiers of Medicine. Feb, 2020 | Pubmed ID: 31280468 Circulating Heme Oxygenase-1 and Complement Activation in Transplant-Associated Thrombotic Microangiopathy Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Aug, 2019 | Pubmed ID: 30871975 Perivascular Adipose Tissue Modulates Carotid Plaque Formation Induced by Disturbed Flow in Mice Journal of Vascular Surgery. Sep, 2019 | Pubmed ID: 30777689 Serum Semaphorin 7A is Associated with the Risk of Acute Atherothrombotic Stroke Journal of Cellular and Molecular Medicine. Apr, 2019 | Pubmed ID: 30729666 Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in Mice Frontiers in Physiology. 2018 | Pubmed ID: 30555351 Semaphorins and Their Receptors: From Axonal Guidance to Atherosclerosis Frontiers in Physiology. 2018 | Pubmed ID: 30405423 HIF 1 Inhibits StAR Transcription and Testosterone Synthesis in Murine Leydig Cells Journal of Molecular Endocrinology. Oct, 2018 | Pubmed ID: 30400066 UV-visible Photocurrent Enhancement Using Metal-semiconductor-metal with Symmetric and Asymmetric Double Schottky Barriers Nanoscale. Jul, 2018 | Pubmed ID: 29947633 Addition of Histone Deacetylase Inhibitors Does Not Improve Prognosis in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia Compared with Hypomethylating Agents Alone: A Systematic Review and Meta-analysis of Seven Prospective Cohort Studies Leukemia Research. Aug, 2018 | Pubmed ID: 29936305 Therapeutic Drug Monitoring and Safety of Voriconazole Therapy in Patients with Child-Pugh Class B and C Cirrhosis: A Multicenter Study International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Jul, 2018 | Pubmed ID: 29793038 The Crosstalk Between Autonomic Nervous System and Blood Vessels International Journal of Physiology, Pathophysiology and Pharmacology. 2018 | Pubmed ID: 29593847 Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial β1 Integrin Arteriosclerosis, Thrombosis, and Vascular Biology. 02, 2018 | Pubmed ID: 29269512 Circulating Trimethylamine N-oxide and the Risk of Cardiovascular Diseases: a Systematic Review and Meta-analysis of 11 Prospective Cohort Studies Journal of Cellular and Molecular Medicine. Jan, 2018 | Pubmed ID: 28782886 Erratum To: Downregulation of Hypoxia-Inducible Factor-1α Contributes to Impaired Megakaryopoiesis in Immune Thrombocytopenia Thrombosis and Haemostasis. Oct, 2017 | Pubmed ID: 33317221 Coordination of Platelet Agonist Signaling During the Hemostatic Response in Vivo Blood Advances. Dec, 2017 | Pubmed ID: 29296928 Downregulation of Hypoxia-inducible Factor-1α Contributes to Impaired Megakaryopoiesis in Immune Thrombocytopenia Thrombosis and Haemostasis. Oct, 2017 | Pubmed ID: 28771276 Megakaryocytic Smad4 Regulates Platelet Function Through Syk and ROCK2 Expression Molecular Pharmacology. Sep, 2017 | Pubmed ID: 28663280 The Diagnostic Value of Susceptibility-weighted Imaging for Ischemic Penumbra in Patients with Acute Ischemic Stroke Technology and Health Care : Official Journal of the European Society for Engineering and Medicine. Jul, 2017 | Pubmed ID: 28582933 A Novel STAT3 Inhibitor Negatively Modulates Platelet Activation and Aggregation Acta Pharmacologica Sinica. May, 2017 | Pubmed ID: 28260800 Glaucocalyxin A Improves Survival in Bleomycin-induced Pulmonary Fibrosis in Mice Biochemical and Biophysical Research Communications. Jan, 2017 | Pubmed ID: 27816453 Rapamycin and Bafilomycin A1 Alter Autophagy and Megakaryopoiesis Platelets. Jan, 2017 | Pubmed ID: 27534900 Helicobacter Pylori Infection Related Long Noncoding RNA (lncRNA) AF147447 Inhibits Gastric Cancer Proliferation and Invasion by Targeting MUC2 and Up-regulating MiR-34c Oncotarget. Dec, 2016 | Pubmed ID: 27835575 Glaucocalyxin A Ameliorates Myocardial Ischemia-Reperfusion Injury in Mice by Suppression of Microvascular Thrombosis Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. Oct, 2016 | Pubmed ID: 27716735 Patterns of Expression of Factor VIII and Von Willebrand Factor by Endothelial Cell Subsets in Vivo Blood. Jul, 2016 | Pubmed ID: 27207787 Role of Autophagy in Megakaryocyte Differentiation and Platelet Formation International Journal of Physiology, Pathophysiology and Pharmacology. 2016 | Pubmed ID: 27186320 Standardization of a Well-controlled in Vivo Mouse Model of Thrombus Formation Induced by Mechanical Injury Thrombosis Research. May, 2016 | Pubmed ID: 26967532 Chronic Stress Facilitates the Development of Deep Venous Thrombosis Oxidative Medicine and Cellular Longevity. 2015 | Pubmed ID: 26576222 Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration Via ERK and JNK Signaling Pathways PloS One. 2015 | Pubmed ID: 25799367 TRPM7 Regulates Vascular Endothelial Cell Adhesion and Tube Formation American Journal of Physiology. Cell Physiology. Feb, 2015 | Pubmed ID: 25472964 Aspirin Enhances Protective Effect of Fish Oil Against Thrombosis and Injury-induced Vascular Remodelling British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25339093 A Corin Variant Identified in Hypertensive Patients That Alters Cytoplasmic Tail and Reduces Cell Surface Expression and Activity Scientific Reports. Dec, 2014 | Pubmed ID: 25488193 Modulation of Platelet Activation and Thrombus Formation Using a Pan-PI3K Inhibitor S14161 PloS One. 2014 | Pubmed ID: 25115838 Paired Immunoglobulin-like Receptor B Regulates Platelet Activation Blood. Oct, 2014 | Pubmed ID: 25075127 Glaucocalyxin A Inhibits Platelet Activation and Thrombus Formation Preferentially Via GPVI Signaling Pathway PloS One. 2013 | Pubmed ID: 24386454 Increased Levels of Plasma Soluble Sema4D in Patients with Heart Failure PloS One. 2013 | Pubmed ID: 23741311 Identification of a Calmodulin-binding Domain in Sema4D That Regulates Its Exodomain Shedding in Platelets Blood. May, 2013 | Pubmed ID: 23564909 Preparation and Evaluation of Zanamivir-loaded Solid Lipid Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2011 | Pubmed ID: 22195851 Preparation and Evaluation of Mannose Receptor Mediated Macrophage Targeting Delivery System Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2011 | Pubmed ID: 22195844 Alterations of Hemostatic Parameters in the Early Development of Allogeneic Hematopoietic Stem Cell Transplantation-related Complications Annals of Hematology. Oct, 2011 | Pubmed ID: 21674145 The Role of Semaphorins and Their Receptors in Platelets: Lessons Learned from Neuronal and Immune Synapses Platelets. 2011 | Pubmed ID: 21668292 Adeno-associated Virus-mediated Survivin Mutant Thr34Ala Cooperates with Oxaliplatin to Inhibit Tumor Growth and Angiogenesis in Colon Cancer Oncology Reports. Apr, 2011 | Pubmed ID: 21279308 Diminished Contact-dependent Reinforcement of Syk Activation Underlies Impaired Thrombus Growth in Mice Lacking Semaphorin 4D Blood. Dec, 2010 | Pubmed ID: 20855865 Reversibly Stabilized Multifunctional Dextran Nanoparticles Efficiently Deliver Doxorubicin into the Nuclei of Cancer Cells Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19937876 Vascular Tissue Dissociation and Exploring Single-Cell Subclusters for Targeted Therapy (Video) | JoVE Fengchan Li1, Zhen Zhu1, Yun Du1, Li Zhu1,2,3, Chaojun Tang1,2,3 1Cyrus Tang Hematology Center, Cyrus Tang Medical Institute, Soochow University, 2Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, 3Suzhou Key Laboratory of Thrombosis and Vascular Biology, Soochow University JoVE 65863 Biology
Vascular Tissue Dissociation and Exploring Single-Cell Subclusters for Targeted Therapy (Video) | JoVE Fengchan Li1, Zhen Zhu1, Yun Du1, Li Zhu1,2,3, Chaojun Tang1,2,3 1Cyrus Tang Hematology Center, Cyrus Tang Medical Institute, Soochow University, 2Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, 3Suzhou Key Laboratory of Thrombosis and Vascular Biology, Soochow University JoVE 65863 Biology