Maarten van Dinther Oncode Institute and Department of Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Maarten van Dinther has not added a biography. If you are Maarten van Dinther and would like to personalize this page please email our Author Liaison for assistance. Publications VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 ALK2 Mutation in a Patient with Down's Syndrome and a Congenital Heart Defect European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 TGFbeta Activates Mitogen- and Stress-activated Protein Kinase-1 (MSK1) to Attenuate Cell Death The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 ALK2 R206H Mutation Linked to Fibrodysplasia Ossificans Progressiva Confers Constitutive Activity to the BMP Type I Receptor and Sensitizes Mesenchymal Cells to BMP-induced Osteoblast Differentiation and Bone Formation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 Autocrine Bone Morphogenetic Protein-9 Signals Through Activin Receptor-like Kinase-2/Smad1/Smad4 to Promote Ovarian Cancer Cell Proliferation Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGF and Inhibitors of TGFbeta Type-I Receptor Kinase Synergistically Promote Blood-vessel Formation by Inducing Alpha5-integrin Expression Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 BMP-9 Signals Via ALK1 and Inhibits BFGF-induced Endothelial Cell Proliferation and VEGF-stimulated Angiogenesis Journal of Cell Science. Mar, 2007 | Pubmed ID: 17311849 The Tumor Suppressor Smad4 is Required for Transforming Growth Factor Beta-induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells Cancer Research. Feb, 2006 | Pubmed ID: 16489022 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 TGF-β Signalering en TGF-β-geïnduceerde Epitheel-naar-mesenchymale overgang bij borstkanker en normale cellen bestuderen Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research
TGF-β Signalering en TGF-β-geïnduceerde Epitheel-naar-mesenchymale overgang bij borstkanker en normale cellen bestuderen Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research