Maarten van Dinther Oncode Institute and Department of Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Maarten van Dinther has not added a biography. If you are Maarten van Dinther and would like to personalize this page please email our Author Liaison for assistance. Publications VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 ALK2 Mutazione in Un Paziente Con Sindrome Di Down E Un Cuore Congenito Difetto European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 TGFbeta Attiva Attivata Mitogene E Lo Stress Della Proteina Chinasi-1 (MSK1) Per Attenuare La Morte Delle Cellule The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 Identificazione Di Un Residuo Chiave Mediando Bone Morphogenetic Protein (BMP) -6 Resistenza All'inibizione Di Zucca Permette BMPs Ingegnerizzati Con Attività Agonista Superiore The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 Mutazione ALK2 R206H Collegato a Fibrodisplasia Ossificante Progressiva Conferisce Attività Costitutiva Di BMP Del Recettore Di Tipo I E Sensibilizza Le Cellule Mesenchimali Alla Formazione Di Osso E Differenziazione Degli Osteoblasti Indotta Da BMP Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 Autocrino Osso Morphogenetic Protein-9 Segnali Attraverso Activin Receptor-like Chinasi-2/Smad1/Smad4 Per Promuovere La Proliferazione Delle Cellule Di Cancro Ovarico Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGF E Inibitori Del TGFbeta Tipo-io Della Chinasi Del Recettore Sinergicamente Promuovere La Formazione Di Vasi Sanguigni Inducendo Espressione Alpha5-integrina Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 BMP-9 Signals Via ALK1 and Inhibits BFGF-induced Endothelial Cell Proliferation and VEGF-stimulated Angiogenesis Journal of Cell Science. Mar, 2007 | Pubmed ID: 17311849 Il Soppressore Del Tumore Smad4 è Richiesto Per Il Fattore Di Crescita Trasformante Beta-indotta Epiteliali Di Mesenchymal Transizione E Metastasi Ossee Delle Cellule Di Cancro Al Seno Cancer Research. Feb, 2006 | Pubmed ID: 16489022 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 Studio della segnalazione β TGF e della transizione epiteliale-mesenchimale indotta da TGF-β nel cancro al seno e nelle cellule normali Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research
Studio della segnalazione β TGF e della transizione epiteliale-mesenchimale indotta da TGF-β nel cancro al seno e nelle cellule normali Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research