Manikandan Paramasivam Department of Cellular and Molecular Medicine University of Copenhagen Biography Publications Institution JoVE Articles Manikandan Paramasivam has not added a biography. If you are Manikandan Paramasivam and would like to personalize this page please email our Author Liaison for assistance. Publications PICH and TOP3A Cooperate to Induce Positive DNA Supercoiling Nature Structural & Molecular Biology. 04, 2019 | Pubmed ID: 30936532 Reconstitution of Anaphase DNA Bridge Recognition and Disjunction Nature Structural & Molecular Biology. 09, 2018 | Pubmed ID: 30177760 Single Molecule Analysis of Laser Localized Interstrand Crosslinks Frontiers in Genetics. 2016 | Pubmed ID: 27242893 MERIT40 Cooperates with BRCA2 to Resolve DNA Interstrand Cross-links Genes & Development. Sep, 2015 | Pubmed ID: 26338419 UHRF1 Contributes to DNA Damage Repair As a Lesion Recognition Factor and Nuclease Scaffold Cell Reports. Mar, 2015 | Pubmed ID: 25818288 Nuclear GIT2 is an ATM Substrate and Promotes DNA Repair Molecular and Cellular Biology. Apr, 2015 | Pubmed ID: 25605334 Arsenite Binds to the RING Finger Domains of RNF20-RNF40 Histone E3 Ubiquitin Ligase and Inhibits DNA Double-strand Break Repair Journal of the American Chemical Society. Sep, 2014 | Pubmed ID: 25170678 ATR-dependent Phosphorylation of FANCM at Serine 1045 is Essential for FANCM Functions Cancer Research. Jul, 2013 | Pubmed ID: 23698467 NEIL1 Responds and Binds to Psoralen-induced DNA Interstrand Crosslinks The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23508956 A Ubiquitin-binding Protein, FAAP20, Links RNF8-mediated Ubiquitination to the Fanconi Anemia DNA Repair Network Molecular Cell. Jul, 2012 | Pubmed ID: 22705371 Primer Extension Reactions As a Tool to Uncover Folding Motifs Within Complex G-rich Sequences: Analysis of the Human KRAS NHE Chemical Communications (Cambridge, England). May, 2011 | Pubmed ID: 21424008 The KRAS Promoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-forming GA-element The Journal of Biological Chemistry. Jul, 2010 | Pubmed ID: 20457603 Cellular Uptake and Binding of Guanidine-modified Phthalocyanines to KRAS/HRAS G-quadruplexes Chemical Communications (Cambridge, England). Jan, 2010 | Pubmed ID: 20062883 Protein HnRNP A1 and Its Derivative Up1 Unfold Quadruplex DNA in the Human KRAS Promoter: Implications for Transcription Nucleic Acids Research. May, 2009 | Pubmed ID: 19282454 Identification of a New G-quadruplex Motif in the KRAS Promoter and Design of Pyrene-modified G4-decoys with Antiproliferative Activity in Pancreatic Cancer Cells Journal of Medicinal Chemistry. Jan, 2009 | Pubmed ID: 19099510 Protein HnRNPA1 Binds to a Critical G-rich Element of KRAS and Unwinds G-quadruplex Structures: Implications in Transcription Nucleic Acids Symposium Series (2004). 2008 | Pubmed ID: 18776302 Triplex Glue by Synthesizing Conjugated Flexible Intercalators Nucleic Acids Symposium Series (2004). 2008 | Pubmed ID: 18776241 Structural Polymorphism Within a Regulatory Element of the Human KRAS Promoter: Formation of G4-DNA Recognized by Nuclear Proteins Nucleic Acids Research. Jun, 2008 | Pubmed ID: 18490377 Purine Twisted-intercalating Nucleic Acids: a New Class of Anti-gene Molecules Resistant to Potassium-induced Aggregation Nucleic Acids Research. Jun, 2008 | Pubmed ID: 18456705 Visualization of Replisome Encounters with an Antigen Tagged Blocking Lesion Jing Zhang*1, Jing Huang*2, Ishani Majumdar1, Ryan C. James3, Julia Gichimu1, Manikandan Paramasivam4, Durga Pokharel5, Himabindu Gali6, Marina A. Bellani1, Michael M Seidman1 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, 2Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, 3Department of Molecular Biology and Genetics, Cornell University, 4Department of Cellular and Molecular Medicine, University of Copenhagen, 5Horizon Discovery, 6Boston University School of Medicine JoVE 61689 Biology Single Molecule Analysis of Laser Localized Psoralen Adducts Jing Huang1, Himabindu Gali1, Julia Gichimu1, Marina A. Bellani1, Durga Pokharel1, Manikandan Paramasivam1, Michael M. Seidman1 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health JoVE 55541 Genetics
Visualization of Replisome Encounters with an Antigen Tagged Blocking Lesion Jing Zhang*1, Jing Huang*2, Ishani Majumdar1, Ryan C. James3, Julia Gichimu1, Manikandan Paramasivam4, Durga Pokharel5, Himabindu Gali6, Marina A. Bellani1, Michael M Seidman1 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, 2Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, 3Department of Molecular Biology and Genetics, Cornell University, 4Department of Cellular and Molecular Medicine, University of Copenhagen, 5Horizon Discovery, 6Boston University School of Medicine JoVE 61689 Biology
Single Molecule Analysis of Laser Localized Psoralen Adducts Jing Huang1, Himabindu Gali1, Julia Gichimu1, Marina A. Bellani1, Durga Pokharel1, Manikandan Paramasivam1, Michael M. Seidman1 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health JoVE 55541 Genetics