Manuel C. Peitsch Biological System Research (BSR) Philip Morris International R&D Biography Publications Institution JoVE Articles Manuel C. Peitsch has not added a biography. If you are Manuel C. Peitsch and would like to personalize this page please email our Author Liaison for assistance. Publications Reputation-based Collaborative Network Biology Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2015 | Pubmed ID: 25592588 Characterization of the Vitrocell® 24/48 in Vitro Aerosol Exposure System Using Mainstream Cigarette Smoke Chemistry Central Journal. 2014 | Pubmed ID: 25411580 Proteomics for Systems Toxicology Computational and Structural Biotechnology Journal. Aug, 2014 | Pubmed ID: 25379146 The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure International Journal of Toxicology. Nov, 2014 | Pubmed ID: 25297719 A Crowd-sourcing Approach for the Construction of Species-specific Cell Signaling Networks Bioinformatics (Oxford, England). Oct, 2014 | Pubmed ID: 25294919 Understanding the Limits of Animal Models As Predictors of Human Biology: Lessons Learned from the Sbv IMPROVER Species Translation Challenge Bioinformatics (Oxford, England). Sep, 2014 | Pubmed ID: 25236459 CSEO - the Cigarette Smoke Exposure Ontology Journal of Biomedical Semantics. 2014 | Pubmed ID: 25093069 In Vitro Systems Toxicology Approach to Investigate the Effects of Repeated Cigarette Smoke Exposure on Human Buccal and Gingival Organotypic Epithelial Tissue Cultures Toxicology Mechanisms and Methods. Oct, 2014 | Pubmed ID: 25046638 Quantification of Biological Network Perturbations for Mechanistic Insight and Diagnostics Using Two-layer Causal Models BMC Bioinformatics. 2014 | Pubmed ID: 25015298 A Vascular Biology Network Model Focused on Inflammatory Processes to Investigate Atherogenesis and Plaque Instability Journal of Translational Medicine. 2014 | Pubmed ID: 24965703 Assessment of a Novel Multi-array Normalization Method Based on Spike-in Control Probes Suitable for MicroRNA Datasets with Global Decreases in Expression BMC Research Notes. 2014 | Pubmed ID: 24886675 The Tobacco Genome Sequence and Its Comparison with Those of Tomato and Potato Nature Communications. 2014 | Pubmed ID: 24807620 A 28-day Rat Inhalation Study with an Integrated Molecular Toxicology Endpoint Demonstrates Reduced Exposure Effects for a Prototypic Modified Risk Tobacco Product Compared with Conventional Cigarettes Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Jun, 2014 | Pubmed ID: 24632068 Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™) Gene Regulation and Systems Biology. 2014 | Pubmed ID: 24596455 Systems Toxicology: from Basic Research to Risk Assessment Chemical Research in Toxicology. Mar, 2014 | Pubmed ID: 24446777 Systems Biology Approach for Evaluating the Biological Impact of Environmental Toxicants in Vitro Chemical Research in Toxicology. Mar, 2014 | Pubmed ID: 24428674 Case Study: the Role of Mechanistic Network Models in Systems Toxicology Drug Discovery Today. Feb, 2014 | Pubmed ID: 23933191 A Decade of Systems Biology: Where Are We and Where Are We Going To? Drug Discovery Today. Feb, 2014 | Pubmed ID: 23769977 Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues BioMed Research International. 2013 | Pubmed ID: 24224167 On Crowd-verification of Biological Networks Bioinformatics and Biology Insights. 2013 | Pubmed ID: 24151423 Cigarette Smoke Induces Molecular Responses in Respiratory Tissues of ApoE(-/-) Mice That Are Progressively Deactivated Upon Cessation Toxicology. Dec, 2013 | Pubmed ID: 24096154 Quantitative Assessment of Biological Impact Using Transcriptomic Data and Mechanistic Network Models Toxicology and Applied Pharmacology. Nov, 2013 | Pubmed ID: 23933166 Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-diseased Lung Cells Using a Dedicated Dataset Bioinformatics and Biology Insights. 2013 | Pubmed ID: 23926424 Confero: an Integrated Contrast Data and Gene Set Platform for Computational Analysis and Biological Interpretation of Omics Data BMC Genomics. 2013 | Pubmed ID: 23895370 A Modular Cell-type Focused Inflammatory Process Network Model for Non-diseased Pulmonary Tissue Bioinformatics and Biology Insights. 2013 | Pubmed ID: 23843693 Reference Genomes and Transcriptomes of Nicotiana Sylvestris and Nicotiana Tomentosiformis Genome Biology. 2013 | Pubmed ID: 23773524 Whole Genome Profiling Physical Map and Ancestral Annotation of Tobacco Hicks Broadleaf The Plant Journal : for Cell and Molecular Biology. Sep, 2013 | Pubmed ID: 23672264 Construction of a Computable Network Model for DNA Damage, Autophagy, Cell Death, and Senescence Bioinformatics and Biology Insights. 2013 | Pubmed ID: 23515068 Human Bronchial Epithelial Cells Exposed in Vitro to Cigarette Smoke at the Air-liquid Interface Resemble Bronchial Epithelium from Human Smokers American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2013 | Pubmed ID: 23355383 Design of a Tobacco Exon Array with Application to Investigate the Differential Cadmium Accumulation Property in Two Tobacco Varieties BMC Genomics. 2012 | Pubmed ID: 23190529 Modulation of Atherogenic Lipidome by Cigarette Smoke in Apolipoprotein E-deficient Mice Atherosclerosis. Dec, 2012 | Pubmed ID: 23102783 Assessment of Network Perturbation Amplitudes by Applying High-throughput Data to Causal Biological Networks BMC Systems Biology. 2012 | Pubmed ID: 22651900 Building an R&D Chemical Registration System Journal of Cheminformatics. 2012 | Pubmed ID: 22650418 Industrial Methodology for Process Verification in Research (IMPROVER): Toward Systems Biology Verification Bioinformatics (Oxford, England). May, 2012 | Pubmed ID: 22423044 A Network-based Approach to Quantifying the Impact of Biologically Active Substances Drug Discovery Today. May, 2012 | Pubmed ID: 22155224 A Computable Cellular Stress Network Model for Non-diseased Pulmonary and Cardiovascular Tissue BMC Systems Biology. 2011 | Pubmed ID: 22011616 Verification of Systems Biology Research in the Age of Collaborative Competition Nature Biotechnology. Sep, 2011 | Pubmed ID: 21904331 Construction of a Computable Cell Proliferation Network Focused on Non-diseased Lung Cells BMC Systems Biology. 2011 | Pubmed ID: 21722388 Automated Comparative Protein Structure Modeling with SWISS-MODEL and Swiss-PdbViewer: a Historical Perspective Electrophoresis. Jun, 2009 | Pubmed ID: 19517507 Text Mining for Biology--the Way Forward: Opinions from Leading Scientists Genome Biology. 2008 | Pubmed ID: 18834498 Computer-assisted Reading in Drug Discovery Expert Opinion on Drug Discovery. Mar, 2007 | Pubmed ID: 23484641 From Proteomics to Systems Biology of Bacterial Pathogens: Approaches, Tools, and Applications Proteomics. Mar, 2007 | Pubmed ID: 17370256 The Application of Systems Biology to Drug Discovery Current Opinion in Chemical Biology. Aug, 2006 | Pubmed ID: 16822703 Competitive Intelligence and Patent Analysis in Drug Discovery Drug Discovery Today. Technologies. 2005 | Pubmed ID: 24981938 Human Aspects of the Management of Drug Discovery Knowledge Drug Discovery Today. Technologies. 2005 | Pubmed ID: 24981937 SWISS-MODEL: An Automated Protein Homology-modeling Server Nucleic Acids Research. Jul, 2003 | Pubmed ID: 12824332 About the Use of Protein Models Bioinformatics (Oxford, England). Jul, 2002 | Pubmed ID: 12117790 Haut Analyse de dépistage du contenu pour évaluer les effets toxicologiques des composants nocifs et potentiellement dangereux (HPHC) Diego Marescotti1, Ignacio Gonzalez Suarez1, Stefano Acali1, Stephanie Johne1, Alexandra Laurent1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological System Research (BSR), Philip Morris International R&D Biology Évaluation de l'impact de l'exposition répétée de organotypiques 3D bronchiques et nasales Tissue Culture modèles Whole fumée de cigarette Diana Kuehn1, Shoaib Majeed1, Emmanuel Guedj1, Remi Dulize1, Karine Baumer1, Anita Iskandar1, Stephanie Boue1, Florian Martin1, Radina Kostadinova1, Carole Mathis1, Nikolai V. Ivanov1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological Systems Research, Philip Morris International R&D, Philip Morris Products S.A. Bioengineering
Haut Analyse de dépistage du contenu pour évaluer les effets toxicologiques des composants nocifs et potentiellement dangereux (HPHC) Diego Marescotti1, Ignacio Gonzalez Suarez1, Stefano Acali1, Stephanie Johne1, Alexandra Laurent1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological System Research (BSR), Philip Morris International R&D Biology
Évaluation de l'impact de l'exposition répétée de organotypiques 3D bronchiques et nasales Tissue Culture modèles Whole fumée de cigarette Diana Kuehn1, Shoaib Majeed1, Emmanuel Guedj1, Remi Dulize1, Karine Baumer1, Anita Iskandar1, Stephanie Boue1, Florian Martin1, Radina Kostadinova1, Carole Mathis1, Nikolai V. Ivanov1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological Systems Research, Philip Morris International R&D, Philip Morris Products S.A. Bioengineering