Markus Waldeck-Weiermair Institute of Molecular Biology and Biochemistry Medical University of Graz Biography Publications Institution JoVE Articles Markus Waldeck-Weiermair has not added a biography. If you are Markus Waldeck-Weiermair and would like to personalize this page please email our Author Liaison for assistance. Publications Intact Mitochondrial Ca(2+) Uniport is Essential for Agonist-induced Activation of Endothelial Nitric Oxide Synthase (eNOS) Free Radical Biology & Medicine. Jan, 2017 | Pubmed ID: 27923677 Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin The Journal of Biological Chemistry. Nov, 2016 | Pubmed ID: 27679490 PRMT1-mediated Methylation of MICU1 Determines the UCP2/3 Dependency of Mitochondrial Ca(2+) Uptake in Immortalized Cells Nature Communications. Sep, 2016 | Pubmed ID: 27642082 Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2016 | Pubmed ID: 27606689 Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo Cell Chemical Biology. Jun, 2016 | Pubmed ID: 27341431 Development of Novel FP-based Probes for Live-cell Imaging of Nitric Oxide Dynamics Nature Communications. Feb, 2016 | Pubmed ID: 26842907 Rearrangement of MICU1 Multimers for Activation of MCU is Solely Controlled by Cytosolic Ca(2.) Scientific Reports. Oct, 2015 | Pubmed ID: 26489515 UCP2 Modulates Single-channel Properties of a MCU-dependent Ca(2+) Inward Current in Mitochondria Pflugers Archiv : European Journal of Physiology. Dec, 2015 | Pubmed ID: 26275882 Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum Sensors (Basel, Switzerland). Jun, 2015 | Pubmed ID: 26053751 Assessment of Mitochondrial Ca²⁺ Uptake Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25631032 TRPV1 Mediates Cellular Uptake of Anandamide and Thus Promotes Endothelial Cell Proliferation and Network-formation Biology Open. Nov, 2014 | Pubmed ID: 25395667 IP3-mediated STIM1 Oligomerization Requires Intact Mitochondrial Ca2+ Uptake Journal of Cell Science. Jul, 2014 | Pubmed ID: 24806964 ATP Increases Within the Lumen of the Endoplasmic Reticulum Upon Intracellular Ca2+ Release Molecular Biology of the Cell. Feb, 2014 | Pubmed ID: 24307679 Mitochondrial Ca(2+) Uniporter (MCU)-dependent and MCU-independent Ca(2+) Channels Coexist in the Inner Mitochondrial Membrane Pflugers Archiv : European Journal of Physiology. Jul, 2014 | Pubmed ID: 24162235 Molecularly Distinct Routes of Mitochondrial Ca2+ Uptake Are Activated Depending on the Activity of the Sarco/endoplasmic Reticulum Ca2+ ATPase (SERCA) The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23592775 Spatiotemporal Correlations Between Cytosolic and Mitochondrial Ca(2+) Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon PloS One. 2012 | Pubmed ID: 23029314 Mitochondrial Ca2+ Uptake 1 (MICU1) and Mitochondrial Ca2+ Uniporter (MCU) Contribute to Metabolism-secretion Coupling in Clonal Pancreatic β-cells The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22904319 Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22556413 Endothelial Mitochondria--less Respiration, More Integration Pflugers Archiv : European Journal of Physiology. Jul, 2012 | Pubmed ID: 22382745 Studying Mitochondrial Ca(2+) Uptake - a Revisit Molecular and Cellular Endocrinology. Apr, 2012 | Pubmed ID: 22100614 Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21613221 Uncoupling Protein 3 Adjusts Mitochondrial Ca(2+) Uptake to High and Low Ca(2+) Signals Cell Calcium. Nov, 2010 | Pubmed ID: 21047682 GPR55-dependent and -independent Ion Signalling in Response to Lysophosphatidylinositol in Endothelial Cells British Journal of Pharmacology. Sep, 2010 | Pubmed ID: 20735417 Mitochondrial Ca2+ Uptake and Not Mitochondrial Motility is Required for STIM1-Orai1-dependent Store-operated Ca2+ Entry Journal of Cell Science. Aug, 2010 | Pubmed ID: 20587595 The Contribution of UCP2 and UCP3 to Mitochondrial Ca(2+) Uptake is Differentially Determined by the Source of Supplied Ca(2+) Cell Calcium. May, 2010 | Pubmed ID: 20403634 Integrin Clustering Enables Anandamide-induced Ca2+ Signaling in Endothelial Cells Via GPR55 by Protection Against CB1-receptor-triggered Repression Journal of Cell Science. May, 2008 | Pubmed ID: 18445684 Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells Emrah Eroglu1, Rene Rost1, Helmut Bischof1, Sandra Blass1, Anna Schreilechner1, Benjamin Gottschalk1, Maria R. Depaoli1, Christiane Klec1, Suphachai Charoensin1, Corina T. Madreiter-Sokolowski1, Jeta Ramadani1, Markus Waldeck-Weiermair1, Wolfgang F. Graier1, Roland Malli1 1Institute of Molecular Biology and Biochemistry, Medical University of Graz JoVE 55486 Biology
Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells Emrah Eroglu1, Rene Rost1, Helmut Bischof1, Sandra Blass1, Anna Schreilechner1, Benjamin Gottschalk1, Maria R. Depaoli1, Christiane Klec1, Suphachai Charoensin1, Corina T. Madreiter-Sokolowski1, Jeta Ramadani1, Markus Waldeck-Weiermair1, Wolfgang F. Graier1, Roland Malli1 1Institute of Molecular Biology and Biochemistry, Medical University of Graz JoVE 55486 Biology