Mary K. Estes Department of Molecular Virology and Microbiology Baylor College of Medicine Biography Publications Institution JoVE Articles Mary K. Estes has not added a biography. If you are Mary K. Estes and would like to personalize this page please email our Author Liaison for assistance. Publications Bile Acid-sensitive Human Norovirus Strains Are Susceptible to Sphingosine-1-phosphate Receptor 2 Inhibition Journal of Virology. Jun, 2024 | Pubmed ID: 38884472 GI.1 Norovirus Neutralizing Antibody Levels Are Correlated with GI.1 Histo-blood Group Antigen-Blocking Antibody Levels The Journal of Infectious Diseases. Jun, 2024 | Pubmed ID: 38864524 Divergent Responses of Human Intestinal Organoid Monolayers Using Commercial in Vitro Cytotoxicity Assays PloS One. 2024 | Pubmed ID: 38857221 2'-Fucosyllactose Inhibits Human Norovirus Replication in Human Intestinal Enteroids BioRxiv : the Preprint Server for Biology. May, 2024 | Pubmed ID: 38853945 N-glycoproteomic Analyses of Human Intestinal Enteroids, Varying in Histo-blood Group Geno- and Phenotypes, Reveal a Wide Repertoire of Fucosylated Glycoproteins Glycobiology. Apr, 2024 | Pubmed ID: 38590172 A Bivalent Human Norovirus Vaccine Induces Homotypic and Heterotypic Neutralizing Antibodies The Journal of Infectious Diseases. May, 2024 | Pubmed ID: 37781879 Infant and Adult Human Intestinal Enteroids Are Morphologically and Functionally Distinct BioRxiv : the Preprint Server for Biology. Feb, 2024 | Pubmed ID: 37292968 Rotavirus-mediated DGAT1 Degradation: A Pathophysiological Mechanism of Viral-induced Malabsorptive Diarrhea Proceedings of the National Academy of Sciences of the United States of America. Dec, 2023 | Pubmed ID: 38079544 Human Intestinal Organoids from Cronkhite-Canada Syndrome Patients Reveal Link Between Serotonin and Proliferation The Journal of Clinical Investigation. Nov, 2023 | Pubmed ID: 37909332 A Single Nanobody Neutralizes Multiple Epochally Evolving Human Noroviruses by Modulating Capsid Plasticity Nature Communications. Oct, 2023 | Pubmed ID: 37845211 Standardization of an Antiviral Pipeline for Human Norovirus in Human Intestinal Enteroids Demonstrates Nitazoxanide Has No to Weak Antiviral Activity Antimicrobial Agents and Chemotherapy. Oct, 2023 | Pubmed ID: 37787556 Nanoparticle-Mediated Therapy with MiR-198 Sensitizes Pancreatic Cancer to Gemcitabine Treatment Through Downregulation of VCP-Mediated Autophagy Pharmaceutics. Jul, 2023 | Pubmed ID: 37631252 Hepatobiliary Organoids Derived from Leporids Support the Replication of Hepatotropic Lagoviruses The Journal of General Virology. Aug, 2023 | Pubmed ID: 37584657 A Standardized Antiviral Pipeline for Human Norovirus in Human Intestinal Enteroids Demonstrates No Antiviral Activity of Nitazoxanide BioRxiv : the Preprint Server for Biology. May, 2023 | Pubmed ID: 37293103 Mapping Human Norovirus Antigens During Infection Reveals the Breadth of the Humoral Immune Response NPJ Vaccines. Jun, 2023 | Pubmed ID: 37280322 Human Sapovirus Replication in Human Intestinal Enteroids Journal of Virology. Apr, 2023 | Pubmed ID: 37039654 CLIC and Membrane Wound Repair Pathways Enable Pandemic Norovirus Entry and Infection Nature Communications. Feb, 2023 | Pubmed ID: 36854760 A DLG1-ARHGAP31-CDC42 Axis is Essential for the Intestinal Stem Cell Response to Fluctuating Niche Wnt Signaling Cell Stem Cell. Feb, 2023 | Pubmed ID: 36640764 Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater Emerging Infectious Diseases. Jul, 2022 | Pubmed ID: 35731177 Evaluation of Heat Inactivation of Human Norovirus in Freshwater Clams Using Human Intestinal Enteroids Viruses. May, 2022 | Pubmed ID: 35632754 Novel Fold of Rotavirus Glycan-binding Domain Predicted by AlphaFold2 and Determined by X-ray Crystallography Communications Biology. May, 2022 | Pubmed ID: 35513489 Rotavirus-Induced Lipid Droplet Biogenesis Is Critical for Virus Replication Frontiers in Physiology. 2022 | Pubmed ID: 35492603 Atomic Structure of the Predominant GII.4 Human Norovirus Capsid Reveals Novel Stability and Plasticity Nature Communications. Mar, 2022 | Pubmed ID: 35273142 Clinical and In Vitro Evidence Favoring Immunoglobulin Treatment of a Chronic Norovirus Infection in a Patient With Common Variable Immunodeficiency The Journal of Infectious Diseases. Nov, 2022 | Pubmed ID: 35255136 Generation of CRISPR-Cas9-mediated Genetic Knockout Human Intestinal Tissue-derived Enteroid Lines by Lentivirus Transduction and Single-cell Cloning Nature Protocols. Apr, 2022 | Pubmed ID: 35197604 Depletion of the Apical Endosome in Response to Viruses and Bacterial Toxins Provides Cell-autonomous Host Defense at Mucosal Surfaces Cell Host & Microbe. Feb, 2022 | Pubmed ID: 35143768 Organoid Models for Infectious Disease Annual Review of Medicine. Jan, 2022 | Pubmed ID: 34644153 Distinct Gene Expression Profiles Between Human Preterm-derived and Adult-derived Intestinal Organoids Exposed to : a Pilot Study Gut. Dec, 2021 | Pubmed ID: 34921063 Yersinia Pseudotuberculosis YopE Prevents Uptake by M Cells and Instigates M Cell Extrusion in Human Ileal Enteroid-derived Monolayers Gut Microbes. Jan-Dec, 2021 | Pubmed ID: 34793276 Single-cell Sequencing of Rotavirus-infected Intestinal Epithelium Reveals Cell-type Specific Epithelial Repair and Tuft Cell Infection Proceedings of the National Academy of Sciences of the United States of America. 11, 2021 | Pubmed ID: 34732579 Glycan Recognition in Human Norovirus Infections Viruses. 10, 2021 | Pubmed ID: 34696500 Norovirus Protease Structure and Antivirals Development Viruses. 10, 2021 | Pubmed ID: 34696498 Author Correction: Broadly Cross-reactive Human Antibodies That Inhibit Genogroup I and II Noroviruses Nature Communications. Oct, 2021 | Pubmed ID: 34650069 Drivers of Transcriptional Variance in Human Intestinal Epithelial Organoids Physiological Genomics. Nov, 2021 | Pubmed ID: 34612061 Use of Human Tissue Stem Cell-derived Organoid Cultures to Model Enterohepatic Circulation American Journal of Physiology. Gastrointestinal and Liver Physiology. 09, 2021 | Pubmed ID: 34288725 Effect of Substrate Stiffness on Human Intestinal Enteroids' Infectivity by Enteroaggregative Escherichia Coli Acta Biomaterialia. 09, 2021 | Pubmed ID: 34280559 Broadly Cross-reactive Human Antibodies That Inhibit Genogroup I and II Noroviruses Nature Communications. 07, 2021 | Pubmed ID: 34262046 Telomere Dysfunction Instigates Inflammation in Inflammatory Bowel Disease Proceedings of the National Academy of Sciences of the United States of America. 07, 2021 | Pubmed ID: 34253611 Norovirus in Cancer Patients: A Review Open Forum Infectious Diseases. Jun, 2021 | Pubmed ID: 34189156 Organoids to Dissect Gastrointestinal Virus-Host Interactions: What Have We Learned? Viruses. 05, 2021 | Pubmed ID: 34071878 Bile Goes Viral Viruses. 05, 2021 | Pubmed ID: 34071855 Microbial Science Research in the Post-COVID Environment MBio. 06, 2021 | Pubmed ID: 34044593 New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids MSphere. 01, 2021 | Pubmed ID: 33504663 A Millifluidic Perfusion Cassette for Studying the Pathogenesis of Enteric Infections Using Ex-Vivo Organoids Annals of Biomedical Engineering. Apr, 2021 | Pubmed ID: 33409849 Protein-Functionalized Poly(ethylene Glycol) Hydrogels As Scaffolds for Monolayer Organoid Culture Tissue Engineering. Part C, Methods. 01, 2021 | Pubmed ID: 33334213 Intestinal Stem Cell-derived Enteroids from Morbidly Obese Patients Preserve Obesity-related Phenotypes: Elevated Glucose Absorption and Gluconeogenesis Molecular Metabolism. 02, 2021 | Pubmed ID: 33246140 Fusobacteriumnucleatum Adheres to Clostridioides Difficile Via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus Gastroenterology. 03, 2021 | Pubmed ID: 33227279 Plasmid-based Reverse Genetics for Probing Phosphorylation-dependent Viroplasm Formation in Rotaviruses Virus Research. 01, 2021 | Pubmed ID: 33053412 Enteropathogenic Escherichia Coli Infection in Cancer and Immunosuppressed Patients Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 05, 2021 | Pubmed ID: 32930708 Rotavirus Induces Intercellular Calcium Waves Through ADP Signaling Science (New York, N.Y.). 11, 2020 | Pubmed ID: 33214249 Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration After Bacterial Cytotoxin Injury IScience. Oct, 2020 | Pubmed ID: 33089106 High-Resolution Mapping of Human Norovirus Antigens Via Genomic Phage Display Library Selections and Deep Sequencing Journal of Virology. 12, 2020 | Pubmed ID: 33055250 Enteroaggregative E. Coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection PLoS Pathogens. 09, 2020 | Pubmed ID: 32986782 Telomere Dysfunction Activates YAP1 to Drive Tissue Inflammation Nature Communications. 09, 2020 | Pubmed ID: 32958778 Histo-blood Group Antigens of Glycosphingolipids Predict Susceptibility of Human Intestinal Enteroids to Norovirus Infection The Journal of Biological Chemistry. 11, 2020 | Pubmed ID: 32913124 Human Norovirus Exhibits Strain-specific Sensitivity to Host Interferon Pathways in Human Intestinal Enteroids Proceedings of the National Academy of Sciences of the United States of America. 09, 2020 | Pubmed ID: 32907944 A Genetically Engineered Rotavirus NSP2 Phosphorylation Mutant Impaired in Viroplasm Formation and Replication Shows an Early Interaction Between VNSP2 and Cellular Lipid Droplets Journal of Virology. 07, 2020 | Pubmed ID: 32461314 CD300lf is the Primary Physiologic Receptor of Murine Norovirus but Not Human Norovirus PLoS Pathogens. 04, 2020 | Pubmed ID: 32251490 Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection MBio. 03, 2020 | Pubmed ID: 32184242 Establishing Human Intestinal Enteroid/Organoid Lines from Preterm Infant and Adult Tissue Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32147796 Models of the Small Intestine: Engineering Challenges and Engineering Solutions Tissue Engineering. Part B, Reviews. 08, 2020 | Pubmed ID: 32046599 Bile Acids and Ceramide Overcome the Entry Restriction for GII.3 Human Norovirus Replication in Human Intestinal Enteroids Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31896578 Comparison of Microneutralization and Histo-Blood Group Antigen-Blocking Assays for Functional Norovirus Antibody Detection The Journal of Infectious Diseases. 02, 2020 | Pubmed ID: 31613328 Two- and Three-Dimensional Bioengineered Human Intestinal Tissue Models for Cryptosporidium Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 31452173 Gut Bacterial Bouncers: Keeping Viral Pathogens out of the Epithelium Cell Host & Microbe. 11, 2019 | Pubmed ID: 31726023 Microbial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors Frontiers in Microbiology. 2019 | Pubmed ID: 31649646 COPII Vesicle Transport Is Required for Rotavirus NSP4 Interaction with the Autophagy Protein LC3 II and Trafficking to Viroplasms Journal of Virology. 12, 2019 | Pubmed ID: 31597778 Use of Organoids to Study Regenerative Responses to Intestinal Damage American Journal of Physiology. Gastrointestinal and Liver Physiology. 12, 2019 | Pubmed ID: 31589468 ICTV Virus Taxonomy Profile: The Journal of General Virology. 11, 2019 | Pubmed ID: 31573467 Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia Gastroenterology. 12, 2019 | Pubmed ID: 31473225 Use of Human Intestinal Enteroids to Detect Human Norovirus Infectivity Emerging Infectious Diseases. 09, 2019 | Pubmed ID: 31441758 Rotavirus Calcium Dysregulation Manifests As Dynamic Calcium Signaling in the Cytoplasm and Endoplasmic Reticulum Scientific Reports. 07, 2019 | Pubmed ID: 31346185 Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges Viruses. Jul, 2019 | Pubmed ID: 31336765 Human Intestinal Enteroids With Inducible Neurogenin-3 Expression As a Novel Model of Gut Hormone Secretion Cellular and Molecular Gastroenterology and Hepatology. Apr, 2019 | Pubmed ID: 31029854 Changes of Tight Junction and Interleukin-8 Expression Using a Human Gastroid Monolayer Model of Helicobacter Pylori Infection Helicobacter. Jun, 2019 | Pubmed ID: 30950121 GII.4 Norovirus Protease Shows PH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site Journal of Virology. Mar, 2019 | Pubmed ID: 30626675 Phosphorylation Cascade Regulates the Formation and Maturation of Rotaviral Replication Factories Proceedings of the National Academy of Sciences of the United States of America. 12, 2018 | Pubmed ID: 30509975 Human Milk Oligosaccharides, Milk Microbiome and Infant Gut Microbiome Modulate Neonatal Rotavirus Infection Nature Communications. 11, 2018 | Pubmed ID: 30479342 Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses Gastroenterology. 12, 2018 | Pubmed ID: 30170116 Bile Acids Target Proteolipid Nano-assemblies of EGFR and Phosphatidic Acid in the Plasma Membrane for Stimulation of MAPK Signaling PloS One. 2018 | Pubmed ID: 30169511 Human Noroviruses: Recent Advances in a 50-year History Current Opinion in Infectious Diseases. 10, 2018 | Pubmed ID: 30102614 Viral Gastroenteritis Lancet (London, England). 07, 2018 | Pubmed ID: 30025810 Human Norovirus Replication in Human Intestinal Enteroids As Model to Evaluate Virus Inactivation Emerging Infectious Diseases. 08, 2018 | Pubmed ID: 30014841 Glycan Recognition in Globally Dominant Human Rotaviruses Nature Communications. 07, 2018 | Pubmed ID: 29980685 Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases Cellular and Molecular Gastroenterology and Hepatology. Mar, 2018 | Pubmed ID: 29675450 Human Organoid Cultures: Transformative New Tools for Human Virus Studies Current Opinion in Virology. 04, 2018 | Pubmed ID: 29656244 Novel Segment- and Host-Specific Patterns of Enteroaggregative Adherence to Human Intestinal Enteroids MBio. 02, 2018 | Pubmed ID: 29463660 Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation Cell Reports. 01, 2018 | Pubmed ID: 29386123 In Vitro Enteroid-derived Three-dimensional Tissue Model of Human Small Intestinal Epithelium with Innate Immune Responses PloS One. 2017 | Pubmed ID: 29186150 Rotavirus Infection Nature Reviews. Disease Primers. Nov, 2017 | Pubmed ID: 29119972 Role for FimH in Extraintestinal Pathogenic Escherichia Coli Invasion and Translocation Through the Intestinal Epithelium Infection and Immunity. 11, 2017 | Pubmed ID: 28808163 Prospects and Challenges in the Development of a Norovirus Vaccine Clinical Therapeutics. Aug, 2017 | Pubmed ID: 28756066 Milk Oligosaccharides Inhibit Human Rotavirus Infectivity in MA104 Cells The Journal of Nutrition. 09, 2017 | Pubmed ID: 28637685 Structural Features of Glycan Recognition Among Viral Pathogens Current Opinion in Structural Biology. 06, 2017 | Pubmed ID: 28591681 Gastrointestinal Microphysiological Systems Experimental Biology and Medicine (Maywood, N.J.). 10, 2017 | Pubmed ID: 28534432 Human Sera Collected Between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades Journal of Virology. 07, 2017 | Pubmed ID: 28468886 Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections Methods in Molecular Biology (Clifton, N.J.). Mar, 2017 | Pubmed ID: 28361480 B-Cell Responses to Intramuscular Administration of a Bivalent Virus-Like Particle Human Norovirus Vaccine Clinical and Vaccine Immunology : CVI. May, 2017 | Pubmed ID: 28249841 The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology Annual Review of Physiology. 02, 2017 | Pubmed ID: 28192061 Identification and Characterization of Single-Chain Antibodies That Specifically Bind GI Noroviruses PloS One. 2017 | Pubmed ID: 28095447 A Paradox of Transcriptional and Functional Innate Interferon Responses of Human Intestinal Enteroids to Enteric Virus Infection Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28069942 Deep Sequencing of Phage-displayed Peptide Libraries Reveals Sequence Motif That Detects Norovirus Protein Engineering, Design & Selection : PEDS. Feb, 2017 | Pubmed ID: 28035012 Diversity in Rotavirus-Host Glycan Interactions: A "Sweet" Spectrum Cellular and Molecular Gastroenterology and Hepatology. May, 2016 | Pubmed ID: 28090561 Human Mini-guts: New Insights into Intestinal Physiology and Host-pathogen Interactions Nature Reviews. Gastroenterology & Hepatology. Nov, 2016 | Pubmed ID: 27677718 Structural Basis for Norovirus Neutralization by an HBGA Blocking Human IgA Antibody Proceedings of the National Academy of Sciences of the United States of America. 10, 2016 | Pubmed ID: 27647885 Editorial Overview: Viruses and Cell Metabolism Current Opinion in Virology. 08, 2016 | Pubmed ID: 27619793 Replication of Human Noroviruses in Stem Cell-derived Human Enteroids Science (New York, N.Y.). 09, 2016 | Pubmed ID: 27562956 Correction for Hesse Et Al., Serological Responses to a Norovirus Nonstructural Fusion Protein After Vaccination and Infection Clinical and Vaccine Immunology : CVI. 08, 2016 | Pubmed ID: 27495982 Replication of Human Norovirus RNA in Mammalian Cells Reveals Lack of Interferon Response Journal of Virology. 10, 2016 | Pubmed ID: 27466422 Detection of Human Norovirus in Intestinal Biopsies from Immunocompromised Transplant Patients The Journal of General Virology. Sep, 2016 | Pubmed ID: 27412790 Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding PLoS Pathogens. 06, 2016 | Pubmed ID: 27355511 Physiologically Relevant Human Tissue Models for Infectious Diseases Drug Discovery Today. 09, 2016 | Pubmed ID: 27352632 Antiviral Targets of Human Noroviruses Current Opinion in Virology. 06, 2016 | Pubmed ID: 27318434 Norovirus Gastroenteritis in a Birth Cohort in Southern India PloS One. 2016 | Pubmed ID: 27284939 Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With BOPV or IPV The Pediatric Infectious Disease Journal. 10, 2016 | Pubmed ID: 27254033 Correlates of Protection Against Norovirus Infection and Disease-Where Are We Now, Where Do We Go? PLoS Pathogens. 04, 2016 | Pubmed ID: 27115358 Enterohemorrhagic Reduce Mucus and Intermicrovillar Bridges in Human Stem Cell-derived Colonoids Cellular and Molecular Gastroenterology and Hepatology. Jan, 2016 | Pubmed ID: 26855967 Human Enteroids As a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology Gastroenterology. Mar, 2016 | Pubmed ID: 26677983 Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26677228 Serological Responses to a Norovirus Nonstructural Fusion Protein After Vaccination and Infection Clinical and Vaccine Immunology : CVI. 02, 2016 | Pubmed ID: 26656120 Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology Journal of Virology. 01, 2016 | Pubmed ID: 26446608 Pathophysiological Consequences of Calcium-Conducting Viroporins Annual Review of Virology. Nov, 2015 | Pubmed ID: 26958925 Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies Journal of Clinical Microbiology. Dec, 2015 | Pubmed ID: 26447115 Structural Basis of Glycan Specificity in Neonate-specific Bovine-human Reassortant Rotavirus Nature Communications. Sep, 2015 | Pubmed ID: 26420502 Serological Correlates of Protection Against a GII.4 Norovirus Clinical and Vaccine Immunology : CVI. Aug, 2015 | Pubmed ID: 26041041 Women in Science: Hints for Success Gastroenterology. Jul, 2015 | Pubmed ID: 26021234 Sensitive Detection of Norovirus Using Phage Nanoparticle Reporters in Lateral-flow Assay PloS One. 2015 | Pubmed ID: 25978622 Noroviruses As a Cause of Diarrhea in Immunocompromised Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2015 | Pubmed ID: 25788003 Mucosal and Cellular Immune Responses to Norwalk Virus The Journal of Infectious Diseases. Aug, 2015 | Pubmed ID: 25635121 Experimental Human Infection with Norwalk Virus Elicits a Surrogate Neutralizing Antibody Response with Cross-genogroup Activity Clinical and Vaccine Immunology : CVI. Feb, 2015 | Pubmed ID: 25540269 Characterization of Cross-reactive Norovirus-specific Monoclonal Antibodies Clinical and Vaccine Immunology : CVI. Feb, 2015 | Pubmed ID: 25428247 Mapping Broadly Reactive Norovirus Genogroup I and II Monoclonal Antibodies Clinical and Vaccine Immunology : CVI. Feb, 2015 | Pubmed ID: 25428246 Norovirus Vaccine Against Experimental Human GII.4 Virus Illness: a Challenge Study in Healthy Adults The Journal of Infectious Diseases. Mar, 2015 | Pubmed ID: 25210140 Reply to Kirby Et Al The Journal of Infectious Diseases. Jan, 2015 | Pubmed ID: 25015947 Viral Infection. Prevention and Cure of Rotavirus Infection Via TLR5/NLRC4-mediated Production of IL-22 and IL-18 Science (New York, N.Y.). Nov, 2014 | Pubmed ID: 25395539 Structural Plasticity of the Coiled-coil Domain of Rotavirus NSP4 Journal of Virology. Dec, 2014 | Pubmed ID: 25231315 Plasmid-based Human Norovirus Reverse Genetics System Produces Reporter-tagged Progeny Virus Containing Infectious Genomic RNA Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014 | Pubmed ID: 25192933 Probing the Sites of Interactions of Rotaviral Proteins Involved in Replication Journal of Virology. Nov, 2014 | Pubmed ID: 25165107 Structural Basis of Glycan Interaction in Gastroenteric Viral Pathogens Current Opinion in Virology. Aug, 2014 | Pubmed ID: 25073118 Structural Characterization by Multistage Mass Spectrometry (MSn) of Human Milk Glycans Recognized by Human Rotaviruses Molecular & Cellular Proteomics : MCP. Nov, 2014 | Pubmed ID: 25048706 Human Milk Contains Novel Glycans That Are Potential Decoy Receptors for Neonatal Rotaviruses Molecular & Cellular Proteomics : MCP. Nov, 2014 | Pubmed ID: 25048705 Development of a Gaussia Luciferase-based Human Norovirus Protease Reporter System: Cell Type-specific Profile of Norwalk Virus Protease Precursors and Evaluation of Inhibitors Journal of Virology. Sep, 2014 | Pubmed ID: 25008934 Identification of Human Single-chain Antibodies with Broad Reactivity for Noroviruses Protein Engineering, Design & Selection : PEDS. Oct, 2014 | Pubmed ID: 24946948 Human Enteroids As an Ex-vivo Model of Host-pathogen Interactions in the Gastrointestinal Tract Experimental Biology and Medicine (Maywood, N.J.). Sep, 2014 | Pubmed ID: 24719375 Structural Analysis of Determinants of Histo-blood Group Antigen Binding Specificity in Genogroup I Noroviruses Journal of Virology. Jun, 2014 | Pubmed ID: 24648450 Seroepidemiology of Norovirus-associated Travelers' Diarrhea Journal of Travel Medicine. Jan-Feb, 2014 | Pubmed ID: 24383649 Determination of the 50% Human Infectious Dose for Norwalk Virus The Journal of Infectious Diseases. Apr, 2014 | Pubmed ID: 24253285 Epidemiology of Human Noroviruses and Updates on Vaccine Development Current Opinion in Gastroenterology. Jan, 2014 | Pubmed ID: 24232370 A Novel Form of Rotavirus NSP2 and Phosphorylation-dependent NSP2-NSP5 Interactions Are Associated with Viroplasm Assembly Journal of Virology. Jan, 2014 | Pubmed ID: 24198401 Human Enteroids: Preclinical Models of Non-inflammatory Diarrhea Stem Cell Research & Therapy. 2013 | Pubmed ID: 24564938 Synthesis, Activity and Structure-Activity Relationship of Noroviral Protease Inhibitors MedChemComm. Oct, 2013 | Pubmed ID: 24244836 Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity Journal of Virology. Dec, 2013 | Pubmed ID: 24109210 Prevention of Cholestasis in the Murine Rotavirus-induced Biliary Atresia Model Using Passive Immunization and Nonreplicating Virus-like Particles Vaccine. Nov, 2013 | Pubmed ID: 23887039 Noroviruses: The Most Common Pediatric Viral Enteric Pathogen at a Large University Hospital After Introduction of Rotavirus Vaccination Journal of the Pediatric Infectious Diseases Society. Mar, 2013 | Pubmed ID: 23687584 Lack of Norovirus Replication and Histo-blood Group Antigen Expression in 3-dimensional Intestinal Epithelial Cells Emerging Infectious Diseases. Mar, 2013 | Pubmed ID: 23622517 The VP8* Domain of Neonatal Rotavirus Strain G10P[11] Binds to Type II Precursor Glycans Journal of Virology. Jul, 2013 | Pubmed ID: 23616650 Exposure to Human and Bovine Noroviruses in a Birth Cohort in Southern India from 2002 to 2006 Journal of Clinical Microbiology. Jul, 2013 | Pubmed ID: 23616452 Identification and Characterization of a Peptide Affinity Reagent for Detection of Noroviruses in Clinical Samples Journal of Clinical Microbiology. Jun, 2013 | Pubmed ID: 23554202 Viroporin-mediated Calcium-activated Autophagy Autophagy. May, 2013 | Pubmed ID: 23442576 Norwalk Virus Minor Capsid Protein VP2 Associates Within the VP1 Shell Domain Journal of Virology. May, 2013 | Pubmed ID: 23408637 Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus Journal of Virology. Apr, 2013 | Pubmed ID: 23365454 A Time-resolved Immunoassay to Measure Serum Antibodies to the Rotavirus VP6 Capsid Protein Journal of Virological Methods. Apr, 2013 | Pubmed ID: 23183143 Autophagy Hijacked Through Viroporin-activated Calcium/calmodulin-dependent Kinase Kinase-β Signaling is Required for Rotavirus Replication Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23184977 Norovirus Vaccine Development: Next Steps Expert Review of Vaccines. Sep, 2012 | Pubmed ID: 23151158 Antibody Responses to Norovirus Genogroup GI.1 and GII.4 Proteases in Volunteers Administered Norwalk Virus Clinical and Vaccine Immunology : CVI. Dec, 2012 | Pubmed ID: 23035177 Secretory Pathway Antagonism by Calicivirus Homologues of Norwalk Virus Nonstructural Protein P22 is Restricted to Noroviruses Virology Journal. Sep, 2012 | Pubmed ID: 22943503 Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity Journal of Virology. Oct, 2012 | Pubmed ID: 22811529 Rotavirus Non-structural Proteins: Structure and Function Current Opinion in Virology. Aug, 2012 | Pubmed ID: 22789743 Rotaviruses: Cause of Vaccine-preventable Disease Yet Many Fundamental Questions Remain to Be Explored Current Opinion in Virology. Aug, 2012 | Pubmed ID: 22762866 Stem Cell-derived Human Intestinal Organoids As an Infection Model for Rotaviruses MBio. 2012 | Pubmed ID: 22761392 Cell Attachment Protein VP8* of a Human Rotavirus Specifically Interacts with A-type Histo-blood Group Antigen Nature. Apr, 2012 | Pubmed ID: 22504179 Genetic Divergence of Rotavirus Nonstructural Protein 4 Results in Distinct Serogroup-specific Viroporin Activity and Intracellular Punctate Structure Morphologies Journal of Virology. May, 2012 | Pubmed ID: 22357281 Serum Hemagglutination Inhibition Activity Correlates with Protection from Gastroenteritis in Persons Infected with Norwalk Virus Clinical and Vaccine Immunology : CVI. Feb, 2012 | Pubmed ID: 22190401 Rotavirus and Biliary Atresia: Can Causation Be Proven? Current Opinion in Gastroenterology. Jan, 2012 | Pubmed ID: 22123643 Norovirus Vaccine Against Experimental Human Norwalk Virus Illness The New England Journal of Medicine. Dec, 2011 | Pubmed ID: 22150036 Prestress Strengthens the Shell of Norwalk Virus Nanoparticles Nano Letters. Nov, 2011 | Pubmed ID: 21967663 Protective Effect of Natural Rotavirus Infection in an Indian Birth Cohort The New England Journal of Medicine. Jul, 2011 | Pubmed ID: 21793745 Osteopontin Upregulation in Rotavirus-induced Murine Biliary Atresia Requires Replicating Virus but is Not Necessary for Development of Biliary Atresia Virology. Sep, 2011 | Pubmed ID: 21742364 Structural Analysis of Histo-blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution Journal of Virology. Sep, 2011 | Pubmed ID: 21715503 Golgi Localization of ERManI Defines Spatial Separation of the Mammalian Glycoprotein Quality Control System Molecular Biology of the Cell. Aug, 2011 | Pubmed ID: 21697506 Uniformity of Rotavirus Strain Nomenclature Proposed by the Rotavirus Classification Working Group (RCWG) Archives of Virology. Aug, 2011 | Pubmed ID: 21597953 Serological Responses to Experimental Norwalk Virus Infection Measured Using a Quantitative Duplex Time-resolved Fluorescence Immunoassay Clinical and Vaccine Immunology : CVI. Jul, 2011 | Pubmed ID: 21593238 Reconciliation of Rotavirus Temperature-sensitive Mutant Collections and Assignment of Reassortment Groups D, J, and K to Genome Segments Journal of Virology. May, 2011 | Pubmed ID: 21367894 Adsorption and Aggregation Properties of Norovirus GI and GII Virus-like Particles Demonstrate Differing Responses to Solution Chemistry Environmental Science & Technology. Jan, 2011 | Pubmed ID: 21121659 Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity MBio. Nov, 2010 | Pubmed ID: 21151776 Inhibition of Cellular Protein Secretion by Norwalk Virus Nonstructural Protein P22 Requires a Mimic of an Endoplasmic Reticulum Export Signal PloS One. Oct, 2010 | Pubmed ID: 20976190 Serological Correlate of Protection Against Norovirus-induced Gastroenteritis The Journal of Infectious Diseases. Oct, 2010 | Pubmed ID: 20815703 An Inside Job: Subversion of the Host Secretory Pathway by Intestinal Pathogens Current Opinion in Infectious Diseases. Oct, 2010 | Pubmed ID: 20717028 Norwalk Virus Does Not Replicate in Human Macrophages or Dendritic Cells Derived from the Peripheral Blood of Susceptible Humans Virology. Oct, 2010 | Pubmed ID: 20667573 Intestinal Epithelia Activate Anti-viral Signaling Via Intracellular Sensing of Rotavirus Structural Components Mucosal Immunology. Nov, 2010 | Pubmed ID: 20664578 Rotavirus Structural Proteins and DsRNA Are Required for the Human Primary Plasmacytoid Dendritic Cell IFNalpha Response PLoS Pathogens. Jun, 2010 | Pubmed ID: 20532161 Norwalk Virus Assembly and Stability Monitored by Mass Spectrometry Molecular & Cellular Proteomics : MCP. Aug, 2010 | Pubmed ID: 20418222 Rotavirus Enterotoxin NSP4 Has Mucosal Adjuvant Properties Vaccine. Apr, 2010 | Pubmed ID: 20197138 Vaccine-acquired Rotavirus in Infants with Severe Combined Immunodeficiency The New England Journal of Medicine. Jan, 2010 | Pubmed ID: 20107217 Burden of Illness in the First 3 Years of Life in an Indian Slum Journal of Tropical Pediatrics. Aug, 2010 | Pubmed ID: 20028725 Norovirus Gastroenteritis The New England Journal of Medicine. Oct, 2009 | Pubmed ID: 19864676 Rotaviruses: from Pathogenesis to Vaccination Gastroenterology. May, 2009 | Pubmed ID: 19457420 Rotavirus Vaccines and Pathogenesis: 2008 Current Opinion in Gastroenterology. Jan, 2009 | Pubmed ID: 19114772 Rotavirus Architecture at Subnanometer Resolution Journal of Virology. Feb, 2009 | Pubmed ID: 19036817 Norwalk Virus Shedding After Experimental Human Infection Emerging Infectious Diseases. Oct, 2008 | Pubmed ID: 18826818 Recommendations for the Classification of Group A Rotaviruses Using All 11 Genomic RNA Segments Archives of Virology. 2008 | Pubmed ID: 18604469 Atomic Resolution Structural Characterization of Recognition of Histo-blood Group Antigens by Norwalk Virus Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18599458 Integrins Alpha1beta1 and Alpha2beta1 Are Receptors for the Rotavirus Enterotoxin Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18587047 Differential Requirements for T Cells in Viruslike Particle- and Rotavirus-induced Protective Immunity Journal of Virology. Mar, 2008 | Pubmed ID: 18184712 Epitope Mapping and Use of Epitope-specific Antisera to Characterize the VP5* Binding Site in Rotavirus SA11 NSP4 Virology. Mar, 2008 | Pubmed ID: 18164740 Norwalk Virus RNA is Infectious in Mammalian Cells Journal of Virology. Nov, 2007 | Pubmed ID: 17855551 Neonatal Infection with G10P[11] Rotavirus Did Not Confer Protection Against Subsequent Rotavirus Infection in a Community Cohort in Vellore, South India The Journal of Infectious Diseases. Mar, 2007 | Pubmed ID: 17262703 Expression of Rotavirus NSP4 Alters the Actin Network Organization Through the Actin Remodeling Protein Cofilin Journal of Virology. Apr, 2007 | Pubmed ID: 17229686 Geographic Information Systems and Genotyping in Identification of Rotavirus G12 Infections in Residents of an Urban Slum with Subsequent Detection in Hospitalized Children: Emergence of G12 Genotype in South India Journal of Clinical Microbiology. Feb, 2007 | Pubmed ID: 17135437 Noroviruses Everywhere: Has Something Changed? Current Opinion in Infectious Diseases. Oct, 2006 | Pubmed ID: 16940871 Cryoelectron Microscopy Structures of Rotavirus NSP2-NSP5 and NSP2-RNA Complexes: Implications for Genome Replication Journal of Virology. Nov, 2006 | Pubmed ID: 16928740 The Epidemiologic and Clinical Importance of Norovirus Infection Gastroenterology Clinics of North America. Jun, 2006 | Pubmed ID: 16880066 Comparative Study of the Epidemiology of Rotavirus in Children from a Community-based Birth Cohort and a Hospital in South India Journal of Clinical Microbiology. Jul, 2006 | Pubmed ID: 16825366 Norwalk Virus-specific Binding to Oyster Digestive Tissues Emerging Infectious Diseases. Jun, 2006 | Pubmed ID: 16707048 X-ray Structure of a Native Calicivirus: Structural Insights into Antigenic Diversity and Host Specificity Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16702551 X-ray Crystallographic Structure of the Norwalk Virus Protease at 1.5-A Resolution Journal of Virology. May, 2006 | Pubmed ID: 16641296 Rotavirus Viremia and Extraintestinal Viral Infection in the Neonatal Rat Model Journal of Virology. May, 2006 | Pubmed ID: 16641274 Host, Viral, and Vaccine Factors That Determine Protective Efficacy Induced by Rotavirus and Virus-like Particles (VLPs) Vaccine. Feb, 2006 | Pubmed ID: 16191453 Evaluation of Serum Antibody Responses Against the Rotavirus Nonstructural Protein NSP4 in Children After Rhesus Rotavirus Tetravalent Vaccination or Natural Infection Clinical and Diagnostic Laboratory Immunology. Oct, 2005 | Pubmed ID: 16210477 Norwalk Virus Infection Associates with Secretor Status Genotyped from Sera Journal of Medical Virology. Sep, 2005 | Pubmed ID: 16032732 Replication and Packaging of Norwalk Virus RNA in Cultured Mammalian Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16002473 PH-induced Conformational Change of the Rotavirus VP4 Spike: Implications for Cell Entry and Antibody Neutralization Journal of Virology. Jul, 2005 | Pubmed ID: 15956598 Identification of Genogroup I and Genogroup II Broadly Reactive Epitopes on the Norovirus Capsid Journal of Virology. Jun, 2005 | Pubmed ID: 15919896 Intestinal TSH Production is Localized in Crypt Enterocytes and in Villus 'hotblocks' and is Coupled to IL-7 Production: Evidence for Involvement of TSH During Acute Enteric Virus Infection Immunology Letters. Jun, 2005 | Pubmed ID: 15894109 B-cell and T-cell Immune Responses to Experimental Helicobacter Pylori Infection in Humans Infection and Immunity. May, 2005 | Pubmed ID: 15845507 Evolutionary Trace Residues in Noroviruses: Importance in Receptor Binding, Antigenicity, Virion Assembly, and Strain Diversity Journal of Virology. Jan, 2005 | Pubmed ID: 15596848 Diagnosis of Norwalk Virus Infection by Indirect Enzyme Immunoassay Detection of Salivary Antibodies to Recombinant Norwalk Virus Antigen Clinical and Diagnostic Laboratory Immunology. Nov, 2004 | Pubmed ID: 15539501 The VP7 Outer Capsid Protein of Rotavirus Induces Polyclonal B-cell Activation Journal of Virology. Jul, 2004 | Pubmed ID: 15194774 Norovirus Disease: Changing Epidemiology and Host Susceptibility Factors Trends in Microbiology. Jun, 2004 | Pubmed ID: 15165606 Inter- and Intragenus Structural Variations in Caliciviruses and Their Functional Implications Journal of Virology. Jun, 2004 | Pubmed ID: 15163740 Laboratory Efforts to Cultivate Noroviruses The Journal of General Virology. Jan, 2004 | Pubmed ID: 14718622 Rotavirus Antigenaemia and Viraemia: a Common Event? Lancet (London, England). Nov, 2003 | Pubmed ID: 14602437 The 3' End of Norwalk Virus MRNA Contains Determinants That Regulate the Expression and Stability of the Viral Capsid Protein VP1: a Novel Function for the VP2 Protein Journal of Virology. Nov, 2003 | Pubmed ID: 14557646 Immunogenicity and Protective Efficacy of Rotavirus 2/6-virus-like Particles Produced by a Dual Baculovirus Expression Vector and Administered Intramuscularly, Intranasally, or Orally to Mice Vaccine. Sep, 2003 | Pubmed ID: 12922123 Two Nonoverlapping Domains on the Norwalk Virus Open Reading Frame 3 (ORF3) Protein Are Involved in the Formation of the Phosphorylated 35K Protein and in ORF3-capsid Protein Interactions Journal of Virology. Mar, 2003 | Pubmed ID: 12610132 Norwalk Virus-like Particle Hemagglutination by Binding to H Histo-blood Group Antigens Journal of Virology. Jan, 2003 | Pubmed ID: 12477845 Cross-reactivity Among Several Recombinant Calicivirus Virus-like Particles (VLPs) with Monoclonal Antibodies Obtained from Mice Immunized Orally with One Type of VLP Journal of Clinical Microbiology. Jul, 2002 | Pubmed ID: 12089262 Sequence Analysis of the VP4, VP6, VP7, and NSP4 Gene Products of the Bovine Rotavirus WC3 Virus Genes. Mar, 2002 | Pubmed ID: 12018701 Norwalk Virus Infection and Disease is Associated with ABO Histo-blood Group Type The Journal of Infectious Diseases. May, 2002 | Pubmed ID: 12001052 Initial Interaction of Rotavirus Strains with N-acetylneuraminic (sialic) Acid Residues on the Cell Surface Correlates with VP4 Genotype, Not Species of Origin Journal of Virology. Apr, 2002 | Pubmed ID: 11907248 Structural Requirements for the Assembly of Norwalk Virus-like Particles Journal of Virology. Apr, 2002 | Pubmed ID: 11907243 VLA-2 (alpha2beta1) Integrin Promotes Rotavirus Entry into Cells but is Not Necessary for Rotavirus Attachment Journal of Virology. Feb, 2002 | Pubmed ID: 11773387 Group A Rotavirus Infection and Age-dependent Diarrheal Disease in Rats: a New Animal Model to Study the Pathophysiology of Rotavirus Infection Journal of Virology. Jan, 2002 | Pubmed ID: 11739670 Differential Infection of Polarized Epithelial Cell Lines by Sialic Acid-dependent and Sialic Acid-independent Rotavirus Strains Journal of Virology. Dec, 2001 | Pubmed ID: 11689665 Recombinant Norwalk Virus-like Particles Administered Intranasally to Mice Induce Systemic and Mucosal (fecal and Vaginal) Immune Responses Journal of Virology. Oct, 2001 | Pubmed ID: 11559804 Trypsin Cleavage Stabilizes the Rotavirus VP4 Spike Journal of Virology. Jul, 2001 | Pubmed ID: 11390607 The Reversible Condensation and Expansion of the Rotavirus Genome Proceedings of the National Academy of Sciences of the United States of America. Feb, 2001 | Pubmed ID: 11171959 Nonculturable Agents of Viral Gastroenteritis Clinical Microbiology Newsletter. Dec, 1997 | Pubmed ID: 32336850 2.7 Å Cryo-EM Structure of Rotavirus Core Protein VP3, a Unique Capping Machine with a Helicase Activity Science Advances. | Pubmed ID: 32494598 Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights Carolyn Bomidi1, Xi-Lei Zeng1, Victoria Poplaski1, Cristian Coarfa2, Mary K. Estes1, Sarah E. Blutt1 1Department of Molecular Virology and Microbiology, Baylor College of Medicine, 2Department of Molecular and Cellular Biology, Baylor College of Medicine JoVE 66749 Biology Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research Vojtech Gabriel1, Christopher Zdyrski1, Dipak K. Sahoo2, Kimberly Dao3, Agnes Bourgois-Mochel2, Jamie Kopper2, Xi-Lei Zeng4, Mary K. Estes4, Jonathan P. Mochel1,3, Karin Allenspach2,3 1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 33D Health Solutions Inc., 4Department of Molecular Virology and Microbiology, Baylor College of Medicine JoVE 63515 Medicine
Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights Carolyn Bomidi1, Xi-Lei Zeng1, Victoria Poplaski1, Cristian Coarfa2, Mary K. Estes1, Sarah E. Blutt1 1Department of Molecular Virology and Microbiology, Baylor College of Medicine, 2Department of Molecular and Cellular Biology, Baylor College of Medicine JoVE 66749 Biology
Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research Vojtech Gabriel1, Christopher Zdyrski1, Dipak K. Sahoo2, Kimberly Dao3, Agnes Bourgois-Mochel2, Jamie Kopper2, Xi-Lei Zeng4, Mary K. Estes4, Jonathan P. Mochel1,3, Karin Allenspach2,3 1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 33D Health Solutions Inc., 4Department of Molecular Virology and Microbiology, Baylor College of Medicine JoVE 63515 Medicine