Meenhard Herlyn Biography Publications JoVE Articles Meenhard Herlyn has not added a biography. If you are Meenhard Herlyn and would like to personalize this page please email our Author Liaison for assistance. Publications Author Correction: Loss of Phd2 Cooperates with BRAF to Drive Melanomagenesis Nature Communications. 03, 2019 | Pubmed ID: 30858377 Genome-wide Prediction of Synthetic Rescue Mediators of Resistance to Targeted and Immunotherapy Molecular Systems Biology. Mar, 2019 | Pubmed ID: 30858180 BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2019 | Pubmed ID: 30765391 ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma Cancer Discovery. 03, 2019 | Pubmed ID: 30563872 Author Correction: PAK Signalling Drives Acquired Drug Resistance to MAPK Inhibitors in BRAF-mutant Melanomas Nature. 01, 2019 | Pubmed ID: 30532003 PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer Cancer Discovery. 02, 2019 | Pubmed ID: 30442709 Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility Cancer Discovery. 01, 2019 | Pubmed ID: 30279173 Loss of Phd2 Cooperates with BRAF to Drive Melanomagenesis Nature Communications. 12, 2018 | Pubmed ID: 30575721 A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade Cell. Nov, 2018 | Pubmed ID: 30388455 Publisher Correction: Robust Prediction of Response to Immune Checkpoint Blockade Therapy in Metastatic Melanoma Nature Medicine. Dec, 2018 | Pubmed ID: 30333558 Frontiers in Pigment Cell and Melanoma Research Pigment Cell & Melanoma Research. 11, 2018 | Pubmed ID: 30281213 Targeting the Warburg Effect Via LDHA Inhibition Engages ATF4 Signaling for Cancer Cell Survival The EMBO Journal. Oct, 2018 | Pubmed ID: 30209241 Robust Prediction of Response to Immune Checkpoint Blockade Therapy in Metastatic Melanoma Nature Medicine. 10, 2018 | Pubmed ID: 30127394 Exosomal PD-L1 Contributes to Immunosuppression and is Associated with Anti-PD-1 Response Nature. 08, 2018 | Pubmed ID: 30089911 Tumor Innate Immunity Primed by Specific Interferon-stimulated Endogenous Retroviruses Nature Medicine. 08, 2018 | Pubmed ID: 30038220 Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2018 | Pubmed ID: 29898988 Endogenous Authentic OCT4A Proteins Directly Regulate FOS/AP-1 Transcription in Somatic Cancer Cells Cell Death & Disease. May, 2018 | Pubmed ID: 29789579 Co-targeting BET and MEK As Salvage Therapy for MAPK and Checkpoint Inhibitor-resistant Melanoma EMBO Molecular Medicine. 05, 2018 | Pubmed ID: 29650805 Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2018 | Pubmed ID: 29563139 Distinct Histone Modifications Denote Early Stress-induced Drug Tolerance in Cancer Oncotarget. Feb, 2018 | Pubmed ID: 29492189 Acetylsalicylic Acid Governs the Effect of Sorafenib in -Mutant Cancers Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 03, 2018 | Pubmed ID: 29196297 MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression The Journal of Investigative Dermatology. 01, 2018 | Pubmed ID: 28927893 Hypoxia-activated Prodrug Enhances Therapeutic Effect of Sunitinib in Melanoma Oncotarget. Dec, 2017 | Pubmed ID: 29383148 Melanoma Therapeutic Strategies That Select Against Resistance by Exploiting MYC-Driven Evolutionary Convergence Cell Reports. Dec, 2017 | Pubmed ID: 29212027 PAK Signalling Drives Acquired Drug Resistance to MAPK Inhibitors in BRAF-mutant Melanomas Nature. 10, 2017 | Pubmed ID: 28953887 Tumor-associated B-cells Induce Tumor Heterogeneity and Therapy Resistance Nature Communications. 09, 2017 | Pubmed ID: 28928360 A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles Cancer Discovery. 11, 2017 | Pubmed ID: 28899863 MEK'ing the Most of P53 Reactivation Therapy in Melanoma The Journal of Investigative Dermatology. Feb, 2012 | Pubmed ID: 22241441 Isolation and Characterization of Mouse and Human Esophageal Epithelial Cells in 3D Organotypic Culture Nature Protocols. 2012 | Pubmed ID: 22240585 Isolation and Cultivation of Dermal Stem Cells That Differentiate into Functional Epidermal Melanocytes Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22057442 Resistance to BRAF Inhibitors: Unraveling Mechanisms and Future Treatment Options Cancer Research. Dec, 2011 | Pubmed ID: 22131348 The Molecular Pathology of Cutaneous Melanoma Cancer Biomarkers : Section A of Disease Markers. 2011 | Pubmed ID: 22112480 Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 22067046 Direct Reprogramming of Melanocytes to Neural Crest Stem-like Cells by One Defined Factor Stem Cells (Dayton, Ohio). Nov, 2011 | Pubmed ID: 21948558 Organometallic Pyridylnaphthalimide Complexes As Protein Kinase Inhibitors Organometallics. Jul, 2011 | Pubmed ID: 21918590 Sorting Through the Many Opportunities for Melanoma Therapy Pigment Cell & Melanoma Research. Oct, 2011 | Pubmed ID: 21899726 A NOTCH3-mediated Squamous Cell Differentiation Program Limits Expansion of EMT-competent Cells That Express the ZEB Transcription Factors Cancer Research. Nov, 2011 | Pubmed ID: 21890822 From Cancer Stem Cells to Tumor Maintenance in Melanoma The Journal of Investigative Dermatology. Aug, 2011 | Pubmed ID: 21654838 Detecting and Targeting Mesenchymal-like Subpopulations Within Squamous Cell Carcinomas Cell Cycle (Georgetown, Tex.). Jun, 2011 | Pubmed ID: 21558812 Will Engineered T Cells Expressing CD20 ScFv Eradicate Melanoma? Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011 | Pubmed ID: 21455210 Targeting BRAF in Advanced Melanoma: a First Step Toward Manageable Disease Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2011 | Pubmed ID: 21447722 Dermis-derived Stem Cells: a Source of Epidermal Melanocytes and Melanoma? Pigment Cell & Melanoma Research. Jun, 2011 | Pubmed ID: 21410654 Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K Cancer Cell. Dec, 2010 | Pubmed ID: 21156289 A Systems Biology Analysis of Metastatic Melanoma Using In-depth Three-dimensional Protein Profiling Proteomics. Dec, 2010 | Pubmed ID: 21136598 Taking the Guesswork out of Uveal Melanoma The New England Journal of Medicine. Dec, 2010 | Pubmed ID: 21083377 A Systems Biology Analysis of Metastatic Melanoma Using In-depth Three-dimensional Protein Profiling Proteomics. Oct, 2010 | Pubmed ID: 21082759 Boris Bastian Pigment Cell & Melanoma Research. Dec, 2010 | Pubmed ID: 20973934 PLX4032, a Potent Inhibitor of the B-Raf V600E Oncogene, Selectively Inhibits V600E-positive Melanomas Pigment Cell & Melanoma Research. Dec, 2010 | Pubmed ID: 20973932 Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth Via Activation of the PRMT5 Methyltransferase Cancer Cell. Oct, 2010 | Pubmed ID: 20951943 BRAF Inhibitor Unveils Its Potential Against Advanced Melanoma Cancer Cell. Oct, 2010 | Pubmed ID: 20951940 NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-dependent Transcriptional Network Gastroenterology. Dec, 2010 | Pubmed ID: 20801121 The Ups and Downs of Transcription Factors in Melanoma Journal of the National Cancer Institute. Aug, 2010 | Pubmed ID: 20660367 Fibroblast-secreted Hepatocyte Growth Factor Plays a Functional Role in Esophageal Squamous Cell Carcinoma Invasion Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534479 Periostin, a Cell Adhesion Molecule, Facilitates Invasion in the Tumor Microenvironment and Annotates a Novel Tumor-invasive Signature in Esophageal Cancer Cancer Research. Jul, 2010 | Pubmed ID: 20516120 Insulin-like Growth Factor-binding Protein-3 Promotes Transforming Growth Factor-{beta}1-mediated Epithelial-to-mesenchymal Transition and Motility in Transformed Human Esophageal Cells Carcinogenesis. Aug, 2010 | Pubmed ID: 20513670 A Temporarily Distinct Subpopulation of Slow-cycling Melanoma Cells is Required for Continuous Tumor Growth Cell. May, 2010 | Pubmed ID: 20478252 Epidermal Growth Factor Receptor and Mutant P53 Expand an Esophageal Cellular Subpopulation Capable of Epithelial-to-mesenchymal Transition Through ZEB Transcription Factors Cancer Research. May, 2010 | Pubmed ID: 20424117 What is a Good Model for Melanoma? The Journal of Investigative Dermatology. Apr, 2010 | Pubmed ID: 20231823 Human Dermal Stem Cells Differentiate into Functional Epidermal Melanocytes Journal of Cell Science. Mar, 2010 | Pubmed ID: 20159965 Embryonic Stem Cells As a Model for Studying Melanocyte Development Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 19907984 Distinct MHC Gene Expression Patterns During Progression of Melanoma Genes, Chromosomes & Cancer. Feb, 2010 | Pubmed ID: 19862823 Placental Gene Transfer: Transgene Screening in Mice for Trophic Effects on the Placenta American Journal of Obstetrics and Gynecology. Nov, 2009 | Pubmed ID: 19716119 Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes Cancer Research. Jul, 2009 | Pubmed ID: 19549918 The Role of BRAF Mutation and P53 Inactivation During Transformation of a Subpopulation of Primary Human Melanocytes The American Journal of Pathology. Jun, 2009 | Pubmed ID: 19389934 Driving in the Melanoma Landscape Experimental Dermatology. Jun, 2009 | Pubmed ID: 19366372 Defining Microenvironments Within Mouse Models That Enhance Tumor Aggressiveness Cancer Biology & Therapy. Feb, 2009 | Pubmed ID: 19182538 Cancer Stem Cells Are Everywhere Nature Medicine. Jan, 2009 | Pubmed ID: 19129778 Integrating Tumor-initiating Cells into the Paradigm for Melanoma Targeted Therapy International Journal of Cancer. Journal International Du Cancer. Mar, 2009 | Pubmed ID: 19089923 Cracking the System: Melanoma Complexity Demands New Therapeutic Approaches Pigment Cell & Melanoma Research. Feb, 2009 | Pubmed ID: 19054340 Matricellular Proteins Produced by Melanocytes and Melanomas: in Search for Functions Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. Dec, 2008 | Pubmed ID: 19308688 A Subpopulation of Mouse Esophageal Basal Cells Has Properties of Stem Cells with the Capacity for Self-renewal and Lineage Specification The Journal of Clinical Investigation. Dec, 2008 | Pubmed ID: 19033657 Cleavage of MCM2 Licensing Protein Fosters Senescence in Human Keratinocytes Cell Cycle (Georgetown, Tex.). Nov, 2008 | Pubmed ID: 19001876 Endothelin-3 Stimulates Survival of Goblet Cells in Organotypic Cultures of Fetal Human Colonic Epithelium American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2008 | Pubmed ID: 18832450 Increased Cyclin D1 Expression Can Mediate BRAF Inhibitor Resistance in BRAF V600E-mutated Melanomas Molecular Cancer Therapeutics. Sep, 2008 | Pubmed ID: 18790768 Bortezomib Induces Apoptosis in Esophageal Squamous Cell Carcinoma Cells Through Activation of the P38 Mitogen-activated Protein Kinase Pathway Molecular Cancer Therapeutics. Sep, 2008 | Pubmed ID: 18790767 Melanoma and the Tumor Microenvironment Current Oncology Reports. Sep, 2008 | Pubmed ID: 18706274 Identification of a Novel Subgroup of Melanomas with KIT/cyclin-dependent Kinase-4 Overexpression Cancer Research. Jul, 2008 | Pubmed ID: 18632627 Melanoma Stem Cells: the Dark Seed of Melanoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2008 | Pubmed ID: 18539969 Structure-based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity ACS Chemical Biology. May, 2008 | Pubmed ID: 18484710 Cytotoxicity of the Matrix Metalloproteinase-activated Anthrax Lethal Toxin is Dependent on Gelatinase Expression and B-RAF Status in Human Melanoma Cells Molecular Cancer Therapeutics. May, 2008 | Pubmed ID: 18483309 Unraveling the Mysteries of IGF-1 Signaling in Melanoma The Journal of Investigative Dermatology. Jun, 2008 | Pubmed ID: 18478012 The Essential Role of Fibroblasts in Esophageal Squamous Cell Carcinoma-induced Angiogenesis Gastroenterology. Jun, 2008 | Pubmed ID: 18439605 Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes Chemistry (Weinheim an Der Bergstrasse, Germany). 2008 | Pubmed ID: 18425743 Salmonella Typhimurium As a Novel RNA Interference Vector for Cancer Gene Therapy Cancer Biology & Therapy. Jan, 2008 | Pubmed ID: 18347415 Learning the ABCs of Melanoma-initiating Cells Cancer Cell. Mar, 2008 | Pubmed ID: 18328422 Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18287029 The Differential Role of L1 in Ovarian Carcinoma and Normal Ovarian Surface Epithelium Cancer Research. Feb, 2008 | Pubmed ID: 18281486 Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma Cancer Research. Feb, 2008 | Pubmed ID: 18245465 Cancer Testis Antigens in Human Melanoma Stem Cells: Expression, Distribution, and Methylation Status Journal of Cellular Physiology. May, 2008 | Pubmed ID: 18205182 Microscale Solution IEF Combined with 2-D DIGE Substantially Enhances Analysis Depth of Complex Proteomes Such As Mammalian Cell and Tissue Extracts Electrophoresis. Feb, 2008 | Pubmed ID: 18186533 The Mitogen-activated Protein/extracellular Signal-regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression when Combined with Docetaxel Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2008 | Pubmed ID: 18172275 Permissive Environment in Postnatal Wounds Induced by Adenoviral-mediated Overexpression of the Anti-inflammatory Cytokine Interleukin-10 Prevents Scar Formation Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jan-Feb, 2008 | Pubmed ID: 18086289 Roadmap for New Opportunities in Melanoma Research Seminars in Oncology. Dec, 2007 | Pubmed ID: 18083380 The Functional Interplay Between EGFR Overexpression, HTERT Activation, and P53 Mutation in Esophageal Epithelial Cells with Activation of Stromal Fibroblasts Induces Tumor Development, Invasion, and Differentiation Genes & Development. Nov, 2007 | Pubmed ID: 17974918 The Many Faces of Notch Signaling in Skin-derived Cells Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Dec, 2007 | Pubmed ID: 17935489 Unraveling Mysteries of the Multifunctional Protein SPARC The Journal of Investigative Dermatology. Nov, 2007 | Pubmed ID: 17934501 Raf Inhibitor Stabilizes Receptor for the Type I Interferon but Inhibits Its Anti-proliferative Effects in Human Malignant Melanoma Cells Cancer Biology & Therapy. Sep, 2007 | Pubmed ID: 17873516 Old Disease, New Culprit: Tumor Stem Cells in Cancer Journal of Cellular Physiology. Dec, 2007 | Pubmed ID: 17786956 Association of Polymorphisms of FAS-1377, FAS-670, and FASL-844 Genes with Risk Factors for Cutaneous Malignant Melanoma Cancer Journal (Sudbury, Mass.). Jul-Aug, 2007 | Pubmed ID: 17762755 Expression of Integrin Alpha10 is Induced in Malignant Melanoma Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2007 | Pubmed ID: 17726260 Application of a BRAF Pyrosequencing Assay for Mutation Detection and Copy Number Analysis in Malignant Melanoma The Journal of Molecular Diagnostics : JMD. Sep, 2007 | Pubmed ID: 17690212 Rewired ERK-JNK Signaling Pathways in Melanoma Cancer Cell. May, 2007 | Pubmed ID: 17482134 Mutant V600E BRAF Increases Hypoxia Inducible Factor-1alpha Expression in Melanoma Cancer Research. Apr, 2007 | Pubmed ID: 17409425 Farming Cells to Rebuild Skin and Melanoma Cancer Biology & Therapy. Mar, 2007 | Pubmed ID: 17374983 Profiles of Chemokine Receptors in Melanocytic Lesions: De Novo Expression of CXCR6 in Melanoma Human Pathology. May, 2007 | Pubmed ID: 17306330 High-throughput Oncogene Mutation Profiling in Human Cancer Nature Genetics. Mar, 2007 | Pubmed ID: 17293865 Dysregulation of Claudin-7 Leads to Loss of E-cadherin Expression and the Increased Invasion of Esophageal Squamous Cell Carcinoma Cells The American Journal of Pathology. Feb, 2007 | Pubmed ID: 17255337 An Organometallic Protein Kinase Inhibitor Pharmacologically Activates P53 and Induces Apoptosis in Human Melanoma Cells Cancer Research. Jan, 2007 | Pubmed ID: 17210701 Microenvironmental Influences in Melanoma Progression Journal of Cellular Biochemistry. Jul, 2007 | Pubmed ID: 17171636 Life Isn't Flat: Taking Cancer Biology to the Next Dimension In Vitro Cellular & Developmental Biology. Animal. Sep-Oct, 2006 | Pubmed ID: 17163781 Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885 Cancer Research. Dec, 2006 | Pubmed ID: 17145850 CCN3 Controls 3D Spatial Localization of Melanocytes in the Human Skin Through DDR1 The Journal of Cell Biology. Nov, 2006 | Pubmed ID: 17101694 Coordinated Functions of E-cadherin and Transforming Growth Factor Beta Receptor II in Vitro and in Vivo Cancer Research. Oct, 2006 | Pubmed ID: 17047049 Differentiation of Normal Skin and Melanoma Using High Resolution Hyperspectral Imaging Cancer Biology & Therapy. Aug, 2006 | Pubmed ID: 16931902 Embryogenesis Meets Tumorigenesis Nature Medicine. Aug, 2006 | Pubmed ID: 16892028 Metastatic Potential of Melanomas Defined by Specific Gene Expression Profiles with No BRAF Signature Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Aug, 2006 | Pubmed ID: 16827748 A New Organotypic Model to Study Cell Interactions in the Intestinal Mucosa European Journal of Gastroenterology & Hepatology. Aug, 2006 | Pubmed ID: 16825910 Multiple Signaling Pathways Must Be Targeted to Overcome Drug Resistance in Cell Lines Derived from Melanoma Metastases Molecular Cancer Therapeutics. May, 2006 | Pubmed ID: 16731745 Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles The American Journal of Pathology. Jun, 2006 | Pubmed ID: 16723703 Cancer Interaction with the Bone Microenvironment: a Workshop of the National Institutes of Health Tumor Microenvironment Study Section The American Journal of Pathology. May, 2006 | Pubmed ID: 16651608 Notch1 Signaling Promotes Primary Melanoma Progression by Activating Mitogen-activated Protein Kinase/phosphatidylinositol 3-kinase-Akt Pathways and Up-regulating N-cadherin Expression Cancer Research. Apr, 2006 | Pubmed ID: 16618740 Defining the Conditions for the Generation of Melanocytes from Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jul, 2006 | Pubmed ID: 16574754 Inhibition of Endothelial Cell Proliferation by Notch1 Signaling is Mediated by Repressing MAPK and PI3K/Akt Pathways and Requires MAML1 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2006 | Pubmed ID: 16571776 Expression of PKC Isoforms in Human Melanocytic Cells in Situ Journal of Dermatological Science. Feb, 2006 | Pubmed ID: 16406501 Molecular Targets in Melanoma: Strategies and Challenges for Diagnosis and Therapy International Journal of Cancer. Journal International Du Cancer. Feb, 2006 | Pubmed ID: 16258898 Targeting Intracellular Signaling Pathways As a Novel Strategy in Melanoma Therapeutics Annals of the New York Academy of Sciences. Nov, 2005 | Pubmed ID: 16382039 Normal Human Melanocyte Homeostasis As a Paradigm for Understanding Melanoma The Journal of Investigative Dermatology. Symposium Proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Nov, 2005 | Pubmed ID: 16358819 Targeting the Stromal Fibroblasts: a Novel Approach to Melanoma Therapy Expert Review of Anticancer Therapy. Dec, 2005 | Pubmed ID: 16336098 Activation of Notch1 Signaling is Required for Beta-catenin-mediated Human Primary Melanoma Progression The Journal of Clinical Investigation. Nov, 2005 | Pubmed ID: 16239965 A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas Cancer Research. Oct, 2005 | Pubmed ID: 16230395 Selective Evolutionary Pressure from the Tissue Microenvironment Drives Tumor Progression Seminars in Cancer Biology. Dec, 2005 | Pubmed ID: 16043361 Information Sharing and Collateral Damage Trends in Molecular Medicine. Aug, 2005 | Pubmed ID: 16002338 Bone Morphogenetic Proteins in Melanoma: Angel or Devil? Cancer Metastasis Reviews. Jun, 2005 | Pubmed ID: 15986135 Metastatic Melanoma Cells. Introduction Cancer Metastasis Reviews. Jun, 2005 | Pubmed ID: 15986131 The RAS/RAF/MEK/ERK and PI3K/AKT Signaling Pathways Present Molecular Targets for the Effective Treatment of Advanced Melanoma Frontiers in Bioscience : a Journal and Virtual Library. 2005 | Pubmed ID: 15970553 Adhesion, Migration and Communication in Melanocytes and Melanoma Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society. Jun, 2005 | Pubmed ID: 15892711 Up-regulated Expression of Zonula Occludens Protein-1 in Human Melanoma Associates with N-cadherin and Contributes to Invasion and Adhesion The American Journal of Pathology. May, 2005 | Pubmed ID: 15855653 The Prevalence of Interferon-alpha Transcription Defects in Malignant Melanoma Melanoma Research. Apr, 2005 | Pubmed ID: 15846141 CXC Chemokine Ligand 12 (stromal Cell-derived Factor 1 Alpha) and CXCR4-dependent Migration of CTLs Toward Melanoma Cells in Organotypic Culture Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15843590 Activation of the DNA Damage Checkpoint and Genomic Instability in Human Precancerous Lesions Nature. Apr, 2005 | Pubmed ID: 15829965 Functional Erythropoietin Autocrine Loop in Melanoma The American Journal of Pathology. Mar, 2005 | Pubmed ID: 15743794 Gene Expression Profiling of Melanoma Cells - Searching the Haystack Journal of Translational Medicine. Jan, 2005 | Pubmed ID: 15649323 Cultivation of Normal Human Epidermal Melanocytes in the Absence of Phorbol Esters Methods in Molecular Medicine. 2005 | Pubmed ID: 15492362 Clinical Protocol. Phase I Trial to Evaluate the Safety of H5.020CMV.PDGF-b and Limb Compression Bandage for the Treatment of Venous Leg Ulcer: Trial A Human Gene Therapy. Oct, 2004 | Pubmed ID: 15585116 Adenoviral Mediated Gene Transfer of PDGF-B Enhances Wound Healing in Type I and Type II Diabetic Wounds Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Sep-Oct, 2004 | Pubmed ID: 15453831 Loitering with Intent: New Evidence for the Role of BRAF Mutations in the Proliferation of Melanocytic Lesions The Journal of Investigative Dermatology. Oct, 2004 | Pubmed ID: 15373800 The Role of Altered Cell-cell Communication in Melanoma Progression Journal of Molecular Histology. Mar, 2004 | Pubmed ID: 15339050 Rapid Apoptosis in the Pulmonary Vasculature Distinguishes Non-metastatic from Metastatic Melanoma Cells Cancer Letters. Sep, 2004 | Pubmed ID: 15327836 Akt/protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt Cancer Research. Jul, 2004 | Pubmed ID: 15231645 Cyclin D1 is Essential for Neoplastic Transformation Induced by Both E6/E7 and E6/E7/ErbB-2 Cooperation in Normal Cells Oncogene. Jul, 2004 | Pubmed ID: 15229656 Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15226295 Reversal of Melanocytic Malignancy by Keratinocytes is an E-cadherin-mediated Process Overriding Beta-catenin Signaling Experimental Cell Research. Jul, 2004 | Pubmed ID: 15194432 Truncation of Activated Leukocyte Cell Adhesion Molecule: a Gateway to Melanoma Metastasis The Journal of Investigative Dermatology. May, 2004 | Pubmed ID: 15140234 Recent Advances in Melanoma Biology The Oncologist. 2004 | Pubmed ID: 15047922 Induction of Melanoma Phenotypes in Human Skin by Growth Factors and Ultraviolet B Cancer Research. Feb, 2004 | Pubmed ID: 14871803 [Melanoma-stroma Interactions and Melanoma Progression] Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Oct, 2003 | Pubmed ID: 16281812 Human Melanoblasts in Culture: Expression of BRN2 and Synergistic Regulation by Fibroblast Growth Factor-2, Stem Cell Factor, and Endothelin-3 The Journal of Investigative Dermatology. Nov, 2003 | Pubmed ID: 14708619 First International Melanoma Research Congress Cancer Biology & Therapy. Nov-Dec, 2003 | Pubmed ID: 14688485 The Great Escape: Another Way for Melanoma to Leave Physiological Control? The Journal of Investigative Dermatology. Oct, 2003 | Pubmed ID: 14632176 Reciprocal Regulation of MelCAM and AKT in Human Melanoma Oncogene. Oct, 2003 | Pubmed ID: 14534536 Axis of Evil: Molecular Mechanisms of Cancer Metastasis Oncogene. Sep, 2003 | Pubmed ID: 14528277 VEGF-A and AlphaVbeta3 Integrin Synergistically Rescue Angiogenesis Via N-Ras and PI3-K Signaling in Human Microvascular Endothelial Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2003 | Pubmed ID: 14519669 Cisplatin Down-regulation of Cellular Fas-associated Death Domain-like Interleukin-1beta-converting Enzyme-like Inhibitory Proteins to Restore Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Human Melanoma Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003 | Pubmed ID: 14519653 Suppression of BRAF(V599E) in Human Melanoma Abrogates Transformation Cancer Research. Sep, 2003 | Pubmed ID: 14500344 BRAF As a Potential Therapeutic Target in Melanoma and Other Malignancies Cancer Cell. Aug, 2003 | Pubmed ID: 12957284 Slit-Robo: Neuronal Guides Signal in Tumor Angiogenesis Cancer Cell. Jul, 2003 | Pubmed ID: 12892705 High Levels of CUG-initiated FGF-2 Expression Cause Chromatin Compaction, Decreased Cardiomyocyte Mitosis, and Cell Death Molecular and Cellular Biochemistry. Apr, 2003 | Pubmed ID: 12841351 Fibroblast Growth Factor-2 but Not Mel-CAM And/or Beta3 Integrin Promotes Progression of Melanocytes to Melanoma Experimental Dermatology. Jun, 2003 | Pubmed ID: 12823444 Tumors As Elusive Targets of T-cell-based Active Immunotherapy Trends in Immunology. Jun, 2003 | Pubmed ID: 12810110 Function and Regulation of Melanoma-stromal Fibroblast Interactions: when Seeds Meet Soil Oncogene. May, 2003 | Pubmed ID: 12789292 The Vascular Phenotype of Melanoma Metastasis Clinical & Experimental Metastasis. 2003 | Pubmed ID: 12741681 P16INK4A and Familial Melanoma Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12710687 Stimulation of Human Colonic Epithelial Cells by Leukemia Inhibitory Factor is Dependent on Collagen-embedded Fibroblasts in Organotypic Culture FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2003 | Pubmed ID: 12692084 Stroma Formation and Angiogenesis by Overexpression of Growth Factors, Cytokines, and Proteolytic Enzymes in Human Skin Grafted to SCID Mice The Journal of Investigative Dermatology. Apr, 2003 | Pubmed ID: 12648235 Constitutive Mitogen-activated Protein Kinase Activation in Melanoma is Mediated by Both BRAF Mutations and Autocrine Growth Factor Stimulation Cancer Research. Feb, 2003 | Pubmed ID: 12591721 Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis Molecular and Cellular Biology. Jan, 2003 | Pubmed ID: 12482957 Differential Response of Primary and Metastatic Melanomas to Neutrophils Attracted by IL-8 International Journal of Cancer. Journal International Du Cancer. Jan, 2003 | Pubmed ID: 12471616 Epidermal Growth Factor Receptor Mediates Increased Cell Proliferation, Migration, and Aggregation in Esophageal Keratinocytes in Vitro and in Vivo The Journal of Biological Chemistry. Jan, 2003 | Pubmed ID: 12435727 Melanoma Development and Progression: a Conspiracy Between Tumor and Host Differentiation; Research in Biological Diversity. Dec, 2002 | Pubmed ID: 12492494 BRAF and RAS Mutations in Human Lung Cancer and Melanoma Cancer Research. Dec, 2002 | Pubmed ID: 12460918 New Approaches to the Biology of Melanoma: a Workshop of the National Institutes of Health Pathology B Study Section The American Journal of Pathology. Nov, 2002 | Pubmed ID: 12414540 Cell-surface Proteolysis, Growth Factor Activation and Intercellular Communication in the Progression of Melanoma Critical Reviews in Oncology/hematology. Oct, 2002 | Pubmed ID: 12398996 The Role of E-cadherin in the Motility and Invasion of Implantation Site Intermediate Trophoblast Placenta. Nov, 2002 | Pubmed ID: 12398810 P53 Alone or in Combination with Antisense Cyclin D1 Induces Apoptosis and Reduces Tumor Size in Human Melanoma Cancer Gene Therapy. Oct, 2002 | Pubmed ID: 12224020 Prospective Molecular Profiling of Melanoma Metastases Suggests Classifiers of Immune Responsiveness Cancer Research. Jul, 2002 | Pubmed ID: 12097256 Fibroblast-dependent Differentiation of Human Microvascular Endothelial Cells into Capillary-like 3-dimensional Networks FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002 | Pubmed ID: 12060671 Cyclin D1 is a Candidate Oncogene in Cutaneous Melanoma Cancer Research. Jun, 2002 | Pubmed ID: 12036934 Adenovirus-mediated Ex Vivo Gene Transfer of Human Vascular Endothelial Growth Factor in a Rabbit Laryngotracheal Reconstruction Model The Annals of Otology, Rhinology, and Laryngology. Apr, 2002 | Pubmed ID: 11991579 Melanoma-stroma Interactions: Structural and Functional Aspects The Lancet Oncology. Jan, 2002 | Pubmed ID: 11905603 Insulin-like Growth Factor-I-induced Migration of Melanoma Cells is Mediated by Interleukin-8 Induction Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research. Feb, 2002 | Pubmed ID: 11864912 Osteonectin/SPARC Induction by Ectopic Beta(3) Integrin in Human Radial Growth Phase Primary Melanoma Cells Cancer Research. Jan, 2002 | Pubmed ID: 11782382 Photocarcinogenesis in Human Adult Skin Grafts Carcinogenesis. Jan, 2002 | Pubmed ID: 11756239 Mechanism for Elimination of a Tumor Suppressor: Aberrant Splicing of a Brain-specific Exon Causes Loss of Function of Bin1 in Melanoma Proceedings of the National Academy of Sciences of the United States of America. Aug, 1999 | Pubmed ID: 10449755 Induction of P21(WAF1/CIP1) and Inhibition of Cdk2 Mediated by the Tumor Suppressor P16(INK4a) Molecular and Cellular Biology. May, 1999 | Pubmed ID: 10207115 Adenoviral Gene Transfer of Beta3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma The American Journal of Pathology. Nov, 1998 | Pubmed ID: 9811334 Production of Humanized Mouse via Thymic Renal Capsule Grafting, CD34+ Cells Injection, and Cytokine Delivery JoVE 62906 Immunology and Infection एक मेलेनोमा रोगी व्युत्पन्न Xenograft मॉडल Min Xiao1, Vito W. Rebecca1, Meenhard Herlyn1 1Wistar Institute JoVE 59508 Cancer Research तीन आयामी मानव त्वचा फिर से संगठित मॉडल: एक टूल सामान्य त्वचा और मेलेनोमा प्रगति का अध्ययन करने के लिए Ling Li1, Mizuho Fukunaga-Kalabis1, Meenhard Herlyn1 1Molecular and Cellular Oncogenesis Program, The Wistar Institute JoVE 2937 Bioengineering
Production of Humanized Mouse via Thymic Renal Capsule Grafting, CD34+ Cells Injection, and Cytokine Delivery JoVE 62906 Immunology and Infection
एक मेलेनोमा रोगी व्युत्पन्न Xenograft मॉडल Min Xiao1, Vito W. Rebecca1, Meenhard Herlyn1 1Wistar Institute JoVE 59508 Cancer Research
तीन आयामी मानव त्वचा फिर से संगठित मॉडल: एक टूल सामान्य त्वचा और मेलेनोमा प्रगति का अध्ययन करने के लिए Ling Li1, Mizuho Fukunaga-Kalabis1, Meenhard Herlyn1 1Molecular and Cellular Oncogenesis Program, The Wistar Institute JoVE 2937 Bioengineering