Megan L Stanifer Department of Molecular Genetics and Microbiology University of Florida Biography Publications Institution JoVE Articles Megan L Stanifer Megan Stanifer is an Assistant Professor at the University of Florida in the Department of Molecular Genetics and Microbiology. She received her bachelors in Chemistry from Boston University and her PhD in Molecular Biology, Cell Biology and Biochemistry from Brown University.Megan has been interested in understanding virus-host interactions since her PhD where she studied the human polyomavirus JCV. She continued studying viruses through her first post-doctoral training at Harvard Medical School where she investigated the entry and fusion of VSV. During a second post-doc at the University of Heidelberg, Germany she began to focus more on enteric pathogens and how they are infecting primary human intestinal cells. During this second post-doc, she began to establish human mini-gut organoid cultures to have a deeper understanding of how the host combats virus infection. Publications Functional Comparison of MERS-coronavirus Lineages Reveals Increased Replicative Fitness of the Recombinant Lineage 5 Nature Communications. 09, 2021 | Pubmed ID: 34493730 Single-cell Analyses Reveal SARS-CoV-2 Interference with Intrinsic Immune Response in the Human Gut Molecular Systems Biology. 04, 2021 | Pubmed ID: 33904651 Importance of Type I and III Interferons at Respiratory and Intestinal Barrier Surfaces Frontiers in Immunology. Month, 2020 | Pubmed ID: 33362795 Development of Feline Ileum- and Colon-Derived Organoids and Their Potential Use to Support Feline Coronavirus Infection Cells. 09, 2020 | Pubmed ID: 32932592 3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway Cell. Jul, 2020 | Pubmed ID: 32610083 Asymmetric Distribution of TLR3 Leads to a Polarized Immune Response in Human Intestinal Epithelial Cells Nature Microbiology. 01, 2020 | Pubmed ID: 31686029 Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells Cells. 08, 2019 | Pubmed ID: 31405163 Type-Specific Crosstalk Modulates Interferon Signaling in Intestinal Epithelial Cells Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. 10, 2019 | Pubmed ID: 31199715 Hypoxic Environment Promotes Barrier Formation in Human Intestinal Epithelial Cells Through Regulation of MicroRNA 320a Expression Molecular and Cellular Biology. 07, 2019 | Pubmed ID: 31061092 Differential Regulation of Type I and Type III Interferon Signaling International Journal of Molecular Sciences. Mar, 2019 | Pubmed ID: 30901970 Differential Induction of Interferon Stimulated Genes Between Type I and Type III Interferons is Independent of Interferon Receptor Abundance PLoS Pathogens. 11, 2018 | Pubmed ID: 30485383 Rubella Virus Strain-Associated Differences in the Induction of Oxidative Stress Are Independent of Their Interferon Activation Viruses. 10, 2018 | Pubmed ID: 30282907 Reversible Fusion Proteins As a Tool to Enhance Uptake of Virus-Functionalized LbL Microcarriers Biomacromolecules. 08, 2018 | Pubmed ID: 29966082 Genome Packaging of Reovirus is Mediated by the Scaffolding Property of the Microtubule Network Cellular Microbiology. 12, 2017 | Pubmed ID: 28672089 Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut Frontiers in Immunology. Month, 2017 | Pubmed ID: 28484457 在生物安全3级(BSL-3)条件下使胃肠道类器官适应病原体感染和单细胞测序 Megan L. Stanifer1,2, Steeve Boulant2,3,4 1Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, 2Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, 3Department of Infectious Diseases, Virology, Heidelberg University Hospital, 4Research Group “Cellular Polarity and Viral Infection”, German Cancer Research Center (DKFZ) JoVE 62857 Immunology and Infection
在生物安全3级(BSL-3)条件下使胃肠道类器官适应病原体感染和单细胞测序 Megan L. Stanifer1,2, Steeve Boulant2,3,4 1Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, 2Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, 3Department of Infectious Diseases, Virology, Heidelberg University Hospital, 4Research Group “Cellular Polarity and Viral Infection”, German Cancer Research Center (DKFZ) JoVE 62857 Immunology and Infection