Mengsu Yang Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre Shenzhen Research Institutes of City University of Hong Kong Biography Publications Institution JoVE Articles Mengsu Yang has not added a biography. If you are Mengsu Yang and would like to personalize this page please email our Author Liaison for assistance. Publications Effects of Direct Current Electric Fields on Lung Cancer Cell Electrotaxis in a PMMA-based Microfluidic Device Analytical and Bioanalytical Chemistry. Jan, 2017 | Pubmed ID: 28078410 Chemoresistant Lung Cancer Stem Cells Display High DNA Repair Capability to Remove Cisplatin-induced DNA Damage British Journal of Pharmacology. Feb, 2017 | Pubmed ID: 27933604 Cell Migration Microfluidics for Electrotaxis-based Heterogeneity Study of Lung Cancer Cells Biosensors & Bioelectronics. Mar, 2017 | Pubmed ID: 27816579 High Sensitivity Plasmonic Biosensor Based on Nanoimprinted Quasi 3D Nanosquares for Cell Detection Nanotechnology. Jul, 2016 | Pubmed ID: 27275952 Icariin Stimulates Differentiation and Suppresses Adipocytic Transdifferentiation of Primary Osteoblasts Through Estrogen Receptor-Mediated Pathway Calcified Tissue International. Aug, 2016 | Pubmed ID: 27061090 Monitoring the Intracellular Calcium Response to a Dynamic Hypertonic Environment Scientific Reports. Mar, 2016 | Pubmed ID: 27004604 Au Nanoparticles Decorated TiO2 Nanotube Arrays As a Recyclable Sensor for Photoenhanced Electrochemical Detection of Bisphenol A Environmental Science & Technology. Apr, 2016 | Pubmed ID: 27002339 Two Chiroptical Modes of Silver Nanospirals Nanotechnology. Mar, 2016 | Pubmed ID: 26876361 Flavonoids of Herba Epimedii Stimulate Osteogenic Differentiation and Suppress Adipogenic Differentiation of Primary Mesenchymal Stem Cells Via Estrogen Receptor Pathway Pharmaceutical Biology. Oct, 2015 | Pubmed ID: 26453492 Microfluidic Platform for Studying Chemotaxis of Adhesive Cells Revealed a Gradient-Dependent Migration and Acceleration of Cancer Stem Cells Analytical Chemistry. Jul, 2015 | Pubmed ID: 26087892 Synthesis, Characterization and Biomedical Application of Multifunctional Luminomagnetic Core-shell Nanoparticles Materials Science & Engineering. C, Materials for Biological Applications. Jan, 2015 | Pubmed ID: 25491957 A Microfluidic Linear Node Array for the Study of Protein-ligand Interactions Lab on a Chip. Oct, 2014 | Pubmed ID: 25140880 Gold Nanoparticles Stimulate Differentiation and Mineralization of Primary Osteoblasts Through the ERK/MAPK Signaling Pathway Materials Science & Engineering. C, Materials for Biological Applications. Sep, 2014 | Pubmed ID: 25063094 Activation of Multiple Signaling Pathways During the Differentiation of Mesenchymal Stem Cells Cultured in a Silicon Nanowire Microenvironment Nanomedicine : Nanotechnology, Biology, and Medicine. Aug, 2014 | Pubmed ID: 24566272 A Dual-mode Nanosensor Based on Carbon Quantum Dots and Gold Nanoparticles for Discriminative Detection of Glutathione in Human Plasma Biosensors & Bioelectronics. Jun, 2014 | Pubmed ID: 24462829 Single Layer Linear Array of Microbeads for Multiplexed Analysis of DNA and Proteins Biosensors & Bioelectronics. Apr, 2014 | Pubmed ID: 24287420 Label-free Detection of Endocrine Disrupting Chemicals by Integrating a Competitive Binding Assay with a Piezoelectric Ceramic Resonator Biosensors & Bioelectronics. Mar, 2014 | Pubmed ID: 24201004 On-site Formation of Emulsions by Controlled Air Plugs Small (Weinheim an Der Bergstrasse, Germany). Feb, 2014 | Pubmed ID: 24030982 Reorganization of Cytoskeleton and Transient Activation of Ca2+ Channels in Mesenchymal Stem Cells Cultured on Silicon Nanowire Arrays ACS Applied Materials & Interfaces. Dec, 2013 | Pubmed ID: 24308382 Nanoparticle-based Signal Generation and Amplification in Microfluidic Devices for Bioanalysis The Analyst. Nov, 2013 | Pubmed ID: 24067742 Coupling Gold Nanoparticles to Silica Nanoparticles Through Disulfide Bonds For glutathione Detection Nanotechnology. Sep, 2013 | Pubmed ID: 23974169 Peptide-bridged Assembly of Hybrid Nanomaterial and Its Application for Caspase-3 Detection ACS Applied Materials & Interfaces. Jul, 2013 | Pubmed ID: 23806127 Detection of Cancer Biomarkers by Piezoelectric Biosensor Using PZT Ceramic Resonator As the Transducer Biosensors & Bioelectronics. Aug, 2013 | Pubmed ID: 23542085 Microfluidics Study of Intracellular Calcium Response to Mechanical Stimulation on Single Suspension Cells Lab on a Chip. Mar, 2013 | Pubmed ID: 23403699 Screen Printing of Solder Resist As Master Substrates for Fabrication of Multi-level Microfluidic Channels and Flask-shaped Microstructures for Cell-based Applications Biosensors & Bioelectronics. Mar, 2013 | Pubmed ID: 23122749 Herbal Formula Astragali Radix and Rehmanniae Radix Exerted Wound Healing Effect on Human Skin Fibroblast Cell Line Hs27 Via the Activation of Transformation Growth Factor (TGF-β) Pathway and Promoting Extracellular Matrix (ECM) Deposition Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Dec, 2012 | Pubmed ID: 23083814 The Dual-effects of LaCl₃ on the Proliferation, Osteogenic Differentiation, and Mineralization of MC3T3-E1 Cells Biological Trace Element Research. Dec, 2012 | Pubmed ID: 22886987 Herba Epimedii Flavonoids Suppress Osteoclastic Differentiation and Bone Resorption by Inducing G2/M Arrest and Apoptosis Biochimie. Dec, 2012 | Pubmed ID: 22796380 Imipramine Inhibits Adipogenic Differentiation in Both 3T3-L1 Preadipocytes and Mouse Marrow Stromal Cells Journal of Genetics and Genomics = Yi Chuan Xue Bao. Apr, 2012 | Pubmed ID: 22546539 The Effects of Ce on the Proliferation, Osteogenic Differentiation and Mineralization Function of MC3T3-E1 Cells in Vitro Biological Trace Element Research. Nov, 2012 | Pubmed ID: 22528784 Transcriptional Profiling of Human Skin Fibroblast Cell Line Hs27 Induced by Herbal Formula Astragali Radix and Rehmanniae Radix Journal of Ethnopharmacology. Dec, 2011 | Pubmed ID: 22075453 Danshen-Gegen Decoction Exerts Proliferative Effect on Rat Cardiac Myoblasts H9c2 Via MAPK and Insulin Pathways Journal of Ethnopharmacology. Oct, 2011 | Pubmed ID: 21907783 Multienzyme-nanoparticles Amplification for Sensitive Virus Genotyping in Microfluidic Microbeads Array Using Au Nanoparticle Probes and Quantum Dots As Labels Biosensors & Bioelectronics. Nov, 2011 | Pubmed ID: 21872460 Integrated Sieving Microstructures on Microchannels for Biological Cell Trapping and Droplet Formation Lab on a Chip. Oct, 2011 | Pubmed ID: 21853193 Gold Nanoparticles Promote Osteogenic Differentiation of Mesenchymal Stem Cells Through P38 MAPK Pathway ACS Nano. Nov, 2010 | Pubmed ID: 21028783 Prevalence and Genotype Distribution of Cervical Human Papillomavirus Infection in Macao Journal of Medical Virology. Oct, 2010 | Pubmed ID: 20827770 Real-time Monitoring of Suspension Cell-cell Communication Using an Integrated Microfluidics Lab on a Chip. Sep, 2010 | Pubmed ID: 20614062 Patterned Growth of Vertically Aligned Silicon Nanowire Arrays for Label-free DNA Detection Using Surface-enhanced Raman Spectroscopy Analytical and Bioanalytical Chemistry. Aug, 2010 | Pubmed ID: 20563793 A Microfluidic Device with Microbead Array for Sensitive Virus Detection and Genotyping Using Quantum Dots As Fluorescence Labels Biosensors & Bioelectronics. Jul, 2010 | Pubmed ID: 20483585 Effect of Carbon Nanotubes on HepG2 Adhesion and Spreading Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20422390 Effects of Carbon Nanotubes on the Proliferation and Differentiation of Primary Osteoblasts Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20422380 Covalently Linked Deoxyribonucleic Acid with Multi-walled Carbon Nanotubes: Synthesis and Characterization Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20422378 Covalent Conjugation of Multi-walled Carbon Nanotubes with Proteins Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20422377 Beta-adrenergic Signals Regulate Adipogenesis of Mouse Mesenchymal Stem Cells Via CAMP/PKA Pathway Molecular and Cellular Endocrinology. Jul, 2010 | Pubmed ID: 20363288 Inhibition of Proliferation and Differentiation of Mesenchymal Stem Cells by Carboxylated Carbon Nanotubes ACS Nano. Apr, 2010 | Pubmed ID: 20218664 Linkage of Angiotensinogen Gene Polymorphisms with Hypertension in a Sibling Study of Hong Kong Chinese Journal of Hypertension. Jun, 2010 | Pubmed ID: 20216084 Beta2- and Beta3-, but Not Beta1-adrenergic Receptors Are Involved in Osteogenesis of Mouse Mesenchymal Stem Cells Via CAMP/PKA Signaling Archives of Biochemistry and Biophysics. Apr, 2010 | Pubmed ID: 20138019 Microfluidic Formation of Single Cell Array for Parallel Analysis of Ca2+ Release-activated Ca2+ (CRAC) Channel Activation and Inhibition Analytical Biochemistry. Jan, 2010 | Pubmed ID: 19751694 Gene Expression Analysis of Human Promyelocytic Leukemia HL-60 Cell Differentiation and Cytotoxicity Induced by Natural and Synthetic Retinoids Life Sciences. Apr, 2009 | Pubmed ID: 26324987 DNA Expression Profiles of Non-small Cell Lung Cancer Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer. Jan, 2009 | Pubmed ID: 20712950 Cell Adhesion and Spreading Behavior on Vertically Aligned Silicon Nanowire Arrays ACS Applied Materials & Interfaces. Jan, 2009 | Pubmed ID: 20355748 Transcriptional Analysis of Doxorubicin-induced Cytotoxicity and Resistance in Human Hepatocellular Carcinoma Cell Lines Liver International : Official Journal of the International Association for the Study of the Liver. Oct, 2009 | Pubmed ID: 19627484 Gene Expression Analysis of Human Promyelocytic Leukemia HL-60 Cell Differentiation and Cytotoxicity Induced by Natural and Synthetic Retinoids Life Sciences. Apr, 2009 | Pubmed ID: 19302803 Synthesis, Characterization and Antitumor Activity of New Type Binuclear Platinum(II) Complexes European Journal of Medicinal Chemistry. May, 2009 | Pubmed ID: 18524422 The Structure and Function of Ribonuclease A Upon Interacting With carbon nanotubes Nanotechnology. Mar, 2008 | Pubmed ID: 21817664 Editorial - Analytical Science in China The Analyst. Sep, 2008 | Pubmed ID: 18709184 COOH-terminal Truncated HBV X Protein Plays Key Role in Hepatocarcinogenesis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2008 | Pubmed ID: 18698024 Proteomic and Transcriptomic Study on the Action of a Cytotoxic Saponin (Polyphyllin D): Induction of Endoplasmic Reticulum Stress and Mitochondria-mediated Apoptotic Pathways Proteomics. Aug, 2008 | Pubmed ID: 18615425 1p31, 7q21 and 18q21 Chromosomal Aberrations and Candidate Genes in Acquired Vinblastine Resistance of Human Cervical Carcinoma KB Cells Oncology Reports. May, 2008 | Pubmed ID: 18425371 CDNA Microarray Analysis of the Differentially Expressed Genes Involved in Murine Pre-osteoclast RAW264.7 Cells Proliferation Stimulated by Dexamethasone Life Sciences. Jan, 2008 | Pubmed ID: 18083200 Colorimetric Oligonucleotide Array for Genotyping of Hepatitis C Virus Based on the 5' Non-coding Region Clinica Chimica Acta; International Journal of Clinical Chemistry. Feb, 2008 | Pubmed ID: 17976565 Synthesis, Cytotoxicity and DNA Binding Levels of Tri-functional Mononuclear Platinum(II) Complexes European Journal of Medicinal Chemistry. Feb, 2008 | Pubmed ID: 17587465 3-D Streamline Steering by Nodes Arrayed in an Entangled Microfluidic Network Lab on a Chip. Dec, 2007 | Pubmed ID: 18030391 Deep Proteome Profiling of Sera from Never-smoked Lung Cancer Patients Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Oct, 2007 | Pubmed ID: 17913442 Generation of Linear and Non-linear Concentration Gradients Along Microfluidic Channel by Microtunnel Controlled Stepwise Addition of Sample Solution Lab on a Chip. Oct, 2007 | Pubmed ID: 17896024 New Furostanol Saponins from the Bulbs of Allium Macrostemon Bunge and Their Cytotoxic Activity Die Pharmazie. Jul, 2007 | Pubmed ID: 17718198 Inhibition of Biochemical Reactions by Silicon Nanowires Through Modulating Enzyme Activities Chembiochem : a European Journal of Chemical Biology. Jul, 2007 | Pubmed ID: 17566125 Effects of Silicon Nanowires on HepG2 Cell Adhesion and Spreading Chembiochem : a European Journal of Chemical Biology. Jul, 2007 | Pubmed ID: 17525918 Dexamethasone Protects RAW264.7 Macrophages from Growth Arrest and Apoptosis Induced by H2O2 Through Alteration of Gene Expression Patterns and Inhibition of Nuclear Factor-kappa B (NF-kappaB) Activity Toxicology. Jul, 2007 | Pubmed ID: 17499901 Cytotoxic Activity of Schisandrolic and Isoschisandrolic Acids Involves Induction of Apoptosis Chemotherapy. 2007 | Pubmed ID: 17496413 Effect of Hypoxia on RAW264.7 Macrophages Apoptosis and Signaling Toxicology. Jun, 2007 | Pubmed ID: 17416447 1,25-dihydroxyvitamin D3 Induces Biphasic NF-kappaB Responses During HL-60 Leukemia Cells Differentiation Through Protein Induction and PI3K/Akt-dependent Phosphorylation/degradation of IkappaB Experimental Cell Research. May, 2007 | Pubmed ID: 17397830 DNA Binding and Cytotoxicity of Ruthenium(II) and Rhenium(I) Complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine Inorganic Chemistry. Feb, 2007 | Pubmed ID: 17257015 Magnolol Suppresses NF-kappaB Activation and NF-kappaB Regulated Gene Expression Through Inhibition of IkappaB Kinase Activation Molecular Immunology. Apr, 2007 | Pubmed ID: 17240450 Hypoxia Induces the Activation of Human Hepatic Stellate Cells LX-2 Through TGF-beta Signaling Pathway FEBS Letters. Jan, 2007 | Pubmed ID: 17187782 Effects of RhDecorin on TGF-beta1 Induced Human Hepatic Stellate Cells LX-2 Activation Biochimica Et Biophysica Acta. Nov, 2006 | Pubmed ID: 17067743 Cytotoxic Cycloartane Triterpene Saponins from Actaea Asiatica Journal of Natural Products. Oct, 2006 | Pubmed ID: 17067171 Dose-dependent Cell-based Assays in V-shaped Microfluidic Channels Lab on a Chip. Jul, 2006 | Pubmed ID: 16804597 A Low Temperature Bonding of Quartz Microfluidic Chip for Serum Lipoproteins Analysis Biomedical Microdevices. Sep, 2006 | Pubmed ID: 16799750 Optical and Electrochemical Detection Techniques for Cell-based Microfluidic Systems Analytical and Bioanalytical Chemistry. Mar, 2006 | Pubmed ID: 16795144 Anti-cancer Activity and Mechanisms of 25-anhydrocimigenol-3-O-beta-D-xylopyranoside Isolated from Souliea Vaginata on Hepatomas Anti-cancer Drugs. Jun, 2006 | Pubmed ID: 16702811 Effect of WeiJia on Carbon Tetrachloride Induced Chronic Liver Injury World Journal of Gastroenterology. Mar, 2006 | Pubmed ID: 16609998 Methyl Protodioscin Induces G2/M Cell Cycle Arrest and Apoptosis in HepG2 Liver Cancer Cells Cancer Letters. Sep, 2006 | Pubmed ID: 16458429 The Cytotoxicity of Naturally Occurring Styryl Lactones Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Feb, 2006 | Pubmed ID: 16428026 Triptolide Induces Bcl-2 Cleavage and Mitochondria Dependent Apoptosis in P53-deficient HL-60 Cells Cancer Letters. Sep, 2006 | Pubmed ID: 16316721 Effective Statistical Features for Coding and Non-coding DNA Sequence Classification for Yeast, C. Elegans and Human International Journal of Bioinformatics Research and Applications. 2005 | Pubmed ID: 18048129 Honokiol Inhibits TNF-alpha-stimulated NF-kappaB Activation and NF-kappaB-regulated Gene Expression Through Suppression of IKK Activation Biochemical Pharmacology. Nov, 2005 | Pubmed ID: 16181613 Water Soluble Luminescent Platinum Terpyridine Complexes with Glycosylated Acetylide and Arylacetylide Ligands: Photoluminescent Properties and Cytotoxicities Chemical Communications (Cambridge, England). Oct, 2005 | Pubmed ID: 16175289 Cytotoxicity of Three Cycloartane Triterpenoids from Cimicifuga Dahurica Cancer Letters. Aug, 2005 | Pubmed ID: 16004933 Impedance Analysis of an Electrode-separated Piezoelectric Sensor As a Surface-monitoring Technique for Gelatin Adsorption on Quartz Surface Journal of Colloid and Interface Science. Jan, 2005 | Pubmed ID: 15571695 Trichosanthin's Interfacial Interactions with Phospholipids: a Monolayer Study Colloids and Surfaces. B, Biointerfaces. Dec, 2004 | Pubmed ID: 15556338 Cluster Analysis of Gene Expression Data Based on Self-splitting and Merging Competitive Learning IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society. Mar, 2004 | Pubmed ID: 15055797 Surface Plasmon Resonance Study of the Molecular Recognition Between Polymerase and DNA Containing Various Mismatches and Conformational Changes of DNA-protein Complexes Biosensors & Bioelectronics. May, 2004 | Pubmed ID: 15046752 Hydrodynamic Simulation of Cell Docking in Microfluidic Channels with Different Dam Structures Lab on a Chip. Feb, 2004 | Pubmed ID: 15007441 Association of Vimentin Overexpression and Hepatocellular Carcinoma Metastasis Oncogene. Jan, 2004 | Pubmed ID: 14647434 Classification of Short Human Exons and Introns Based on Statistical Features Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Jun, 2003 | Pubmed ID: 16241270 Interaction Between Pyridoxal Kinase and Pyridoxal-5-phosphate-dependent Enzymes Journal of Biochemistry. Nov, 2003 | Pubmed ID: 14688239 Effects of DNA Mismatches on Binding Affinity and Kinetics of Polymerase-DNA Complexes As Revealed by Surface Plasmon Resonance Biosensor The Analyst. Sep, 2003 | Pubmed ID: 14529025 PDMS-based Microfluidic Device with Multi-height Structures Fabricated by Single-step Photolithography Using Printed Circuit Board As Masters The Analyst. Sep, 2003 | Pubmed ID: 14529020 Bis-intercalative Dinuclear Platinum(II) 6-phenyl-2,2'-bipyridine Complexes Exhibit Enhanced DNA Affinity but Similar Cytotoxicity Compared to the Mononuclear Unit Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Sep, 2003 | Pubmed ID: 12884091 Inhibitory Actions of Genistein in Human Breast Cancer (MCF-7) Cells Biochimica Et Biophysica Acta. Jul, 2003 | Pubmed ID: 12853125 Electrochemical Properties of DNA-intercalating Doxorubicin and Methylene Blue on N-hexadecyl Mercaptan-doped 5'-thiol-labeled DNA-modified Gold Electrodes Biosensors & Bioelectronics. Jul, 2003 | Pubmed ID: 12713910 CDNA Microarray Analysis of Gene Expression Profiles in Human Fibroblast Cells Irradiated with Red Light The Journal of Investigative Dermatology. May, 2003 | Pubmed ID: 12713592 Pyranocoumarins Isolated from Peucedanum Praeruptorum As Differentiation Inducers in Human Leukemic HL-60 Cells Planta Medica. Mar, 2003 | Pubmed ID: 12677525 Synthesis and Biological Activity of a Platinum(II) 6-phenyl-2,2'-bipyridine Complex and Its Dimeric Analogue Chembiochem : a European Journal of Chemical Biology. Jan, 2003 | Pubmed ID: 12512077 Generation of Concentration Gradient by Controlled Flow Distribution and Diffusive Mixing in a Microfluidic Chip Lab on a Chip. Aug, 2002 | Pubmed ID: 15100827 Cell Docking and On-chip Monitoring of Cellular Reactions with a Controlled Concentration Gradient on a Microfluidic Device Analytical Chemistry. Aug, 2002 | Pubmed ID: 12199565 Impedance Analysis of an Electrode-separated Piezoelectric Sensor As a Surface Monitoring Technique for Surfactant Adsorption on Quartz Surface The Analyst. Jul, 2002 | Pubmed ID: 12173654 Syntheses of Ruthenium(II) Quinonediimine Complexes of Cyclam and Characterization of Their DNA-binding Activities and Cytotoxicity Inorganic Chemistry. Jun, 2002 | Pubmed ID: 12054995 Study of Substrate-enzyme Interaction Between Immobilized Pyridoxamine and Recombinant Porcine Pyridoxal Kinase Using Surface Plasmon Resonance Biosensor Biochimica Et Biophysica Acta. Apr, 2002 | Pubmed ID: 11983425 Kinetic Study of Various Binding Modes Between Human DNA Polymerase Beta and Different DNA Substrates by Surface-plasmon-resonance Biosensor The Biochemical Journal. Jan, 2002 | Pubmed ID: 11772403 Modellering äggstockscancer flercelliga Sfäroid Beteende i en dynamisk 3D Peritoneal mikroanordning Shan-Shan Li*1, Carman K. M. Ip*1, Matthew Y. H. Tang*2, Samuel K. H. Sy2, Susan Yung3, Tak-Mao Chan3, Mengsu Yang4, Ho Cheung Shum2, Alice S.T. Wong1 1School of Biological Sciences, University of Hong Kong, 2Department of Mechanical Engineering, University of Hong Kong, 3Department of Medicine, University of Hong Kong, 4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong JoVE 55337 Bioengineering
Modellering äggstockscancer flercelliga Sfäroid Beteende i en dynamisk 3D Peritoneal mikroanordning Shan-Shan Li*1, Carman K. M. Ip*1, Matthew Y. H. Tang*2, Samuel K. H. Sy2, Susan Yung3, Tak-Mao Chan3, Mengsu Yang4, Ho Cheung Shum2, Alice S.T. Wong1 1School of Biological Sciences, University of Hong Kong, 2Department of Mechanical Engineering, University of Hong Kong, 3Department of Medicine, University of Hong Kong, 4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong JoVE 55337 Bioengineering