Michael R. Gold Department of Microbiology and Immunology University of British Columbia Biography Publications Institution JoVE Articles Michael R. Gold has not added a biography. If you are Michael R. Gold and would like to personalize this page please email our Author Liaison for assistance. Publications The Rap2c GTPase Facilitates B Cell Receptor-induced Reorientation of the Microtubule-organizing Center Small GTPases. Feb, 2018 | Pubmed ID: 29457987 Imaging the Interactions Between B Cells and Antigen-Presenting Cells Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29388105 The Interaction of Sex, Height, and QRS Duration on the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality: an Individual-patient Data Meta-analysis European Journal of Heart Failure. Jan, 2018 | Pubmed ID: 29314424 Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials Circulation. Heart Failure. Oct, 2017 | Pubmed ID: 29038172 Limitations of Qdot Labelling Compared to Directly-conjugated Probes for Single Particle Tracking of B Cell Receptor Mobility Scientific Reports. Sep, 2017 | Pubmed ID: 28900238 Predictors of Short-term Clinical Response to Cardiac Resynchronization Therapy European Journal of Heart Failure. Aug, 2017 | Pubmed ID: 28295869 The Rap1-cofilin-1 Pathway Coordinates Actin Reorganization and MTOC Polarization at the B Cell Immune Synapse Journal of Cell Science. 03, 2017 | Pubmed ID: 28167682 Applied Stretch Initiates Directional Invasion Through the Action of Rap1 GTPase As a Tension Sensor Journal of Cell Science. 01, 2017 | Pubmed ID: 27199371 What Goes Up Must Come Down: A Tripartite Dok-3/Grb2/SHIP1 Inhibitory Module Limits BCR Signaling European Journal of Immunology. Nov, 2016 | Pubmed ID: 27813071 SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling Developmental Cell. Apr, 2016 | Pubmed ID: 27046831 The Paracaspase MALT1 Cleaves HOIL1 Reducing Linear Ubiquitination by LUBAC to Dampen Lymphocyte NF-κB Signalling Nature Communications. Nov, 2015 | Pubmed ID: 26525107 Toll-like Receptor Ligands Sensitize B-cell Receptor Signalling by Reducing Actin-dependent Spatial Confinement of the Receptor Nature Communications. Feb, 2015 | Pubmed ID: 25644899 PI3K Signaling in B Cell and T Cell Biology Frontiers in Immunology. 2014 | Pubmed ID: 25404931 An Individual Patient Meta-analysis of Five Randomized Trials Assessing the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality in Patients with Symptomatic Heart Failure European Heart Journal. Dec, 2013 | Pubmed ID: 23900696 Control of the Hippo Pathway by Set7-dependent Methylation of Yap Developmental Cell. Jul, 2013 | Pubmed ID: 23850191 The Invasion Inhibitor Sarasinoside A1 Reverses Mesenchymal Tumor Transformation in an E-cadherin-independent Manner Molecular Cancer Research : MCR. May, 2013 | Pubmed ID: 23399642 Selective Pharmacological Inhibition of Phosphoinositide 3-kinase P110delta Opposes the Progression of Autoimmune Diabetes in Non-obese Diabetic (NOD) Mice Autoimmunity. Feb, 2013 | Pubmed ID: 23039284 Small Molecule Inhibitors of the Pyk2 and FAK Kinases Modulate Chemoattractant-induced Migration, Adhesion and Akt Activation in Follicular and Marginal Zone B Cells Cellular Immunology. Jan-Feb, 2012 | Pubmed ID: 22507871 Cofilin-mediated F-actin Severing is Regulated by the Rap GTPase and Controls the Cytoskeletal Dynamics That Drive Lymphocyte Spreading and BCR Microcluster Formation Journal of Immunology (Baltimore, Md. : 1950). Dec, 2011 | Pubmed ID: 22068232 Opposing Roles for CD34 in B16 Melanoma Tumor Growth Alter Early Stage Vasculature and Late Stage Immune Cell Infiltration PloS One. Apr, 2011 | Pubmed ID: 21494591 TNFR1 Delivers Pro-survival Signals That Are Required for Limiting TNFR2-dependent Activation-induced Cell Death (AICD) in CD8+ T Cells European Journal of Immunology. Feb, 2011 | Pubmed ID: 21268004 Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the Lungs Cancer Research. Jun, 2010 | Pubmed ID: 20484042 Rap GTPase-mediated Adhesion and Migration: A Target for Limiting the Dissemination of B-cell Lymphomas? Cell Adhesion & Migration. Jul-Sep, 2010 | Pubmed ID: 20212359 Phosphoinositide 3-kinase P110 Delta Regulates Natural Antibody Production, Marginal Zone and B-1 B Cell Function, and Autoantibody Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2009 | Pubmed ID: 19843950 Localized Diacylglycerol-dependent Stimulation of Ras and Rap1 During Phagocytosis The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19700408 B Cell Receptor-induced Phosphorylation of Pyk2 and Focal Adhesion Kinase Involves Integrins and the Rap GTPases and is Required for B Cell Spreading The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19561089 Lymphocytes in the Peritoneum Home to the Omentum and Are Activated by Resident Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19553538 B Cell Development: Important Work for ERK Immunity. Apr, 2008 | Pubmed ID: 18400191 The Rap GTPases Regulate B Cell Morphology, Immune-synapse Formation, and Signaling by Particulate B Cell Receptor Ligands Immunity. Jan, 2008 | Pubmed ID: 18191594 Differential Role of Reactive Oxygen Species in the Activation of Mitogen-activated Protein Kinases and Akt by Key Receptors on B-lymphocytes: CD40, the B Cell Antigen Receptor, and CXCR4 Journal of Cell Communication and Signaling. Jun, 2007 | Pubmed ID: 18481208 The Rap GTPases Mediate CXCL13- and Sphingosine1-phosphate-induced Chemotaxis, Adhesion, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes European Journal of Immunology. Aug, 2006 | Pubmed ID: 16821235 The Rap GTPases Regulate Integrin-mediated Adhesion, Cell Spreading, Actin Polymerization, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14701796 Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12904304 Akt is TCL-ish: Implications for B-cell Lymphoma Trends in Immunology. Mar, 2003 | Pubmed ID: 12615201 The Human Antimicrobial Peptide LL-37 is a Multifunctional Modulator of Innate Immune Responses Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244186 The Rap GTPases Regulate B Cell Migration Toward the Chemokine Stromal Cell-derived Factor-1 (CXCL12): Potential Role for Rap2 in Promoting B Cell Migration Journal of Immunology (Baltimore, Md. : 1950). Aug, 2002 | Pubmed ID: 12133960 To Make Antibodies or Not: Signaling by the B-cell Antigen Receptor Trends in Pharmacological Sciences. Jul, 2002 | Pubmed ID: 12119152 The B Cell Antigen Receptor Regulates the Transcriptional Activator Beta-catenin Via Protein Kinase C-mediated Inhibition of Glycogen Synthase Kinase-3 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002 | Pubmed ID: 12097378 Activation and Phosphatidylinositol 3-kinase-dependent Phosphorylation of Protein Kinase C-epsilon by the B Cell Antigen Receptor Immunology Letters. Jul, 2002 | Pubmed ID: 12036603 The Direct Recruitment of BLNK to Immunoglobulin Alpha Couples the B-cell Antigen Receptor to Distal Signaling Pathways Molecular and Cellular Biology. Apr, 2002 | Pubmed ID: 11909947 CD40 Signaling in B Cells Regulates the Expression of the Pim-1 Kinase Via the NF-kappa B Pathway Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777968 Interaction of Cationic Peptides with Lipoteichoic Acid and Gram-positive Bacteria Infection and Immunity. Dec, 1999 | Pubmed ID: 10569762 Dendritic Cell Survival and Maturation Are Regulated by Different Signaling Pathways The Journal of Experimental Medicine. Dec, 1998 | Pubmed ID: 9841930 Listeria Monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-activated Protein Kinase Pathway Infection and Immunity. Mar, 1998 | Pubmed ID: 9488402 Visualisere aktin og mikrotubulus Cytoskeletons på B-celle immun Synapse ved hjælp af stimuleret Emission udtynding (STED) mikroskopi Jia C. Wang1, Madison Bolger-Munro1, Michael R. Gold1 1Department of Microbiology and Immunology, University of British Columbia JoVE 57028 Immunology and Infection
Visualisere aktin og mikrotubulus Cytoskeletons på B-celle immun Synapse ved hjælp af stimuleret Emission udtynding (STED) mikroskopi Jia C. Wang1, Madison Bolger-Munro1, Michael R. Gold1 1Department of Microbiology and Immunology, University of British Columbia JoVE 57028 Immunology and Infection