Michael R. Gold Department of Microbiology and Immunology University of British Columbia Biography Publications Institution JoVE Articles Michael R. Gold has not added a biography. If you are Michael R. Gold and would like to personalize this page please email our Author Liaison for assistance. Publications The Rap2c GTPase Facilitates B Cell Receptor-induced Reorientation of the Microtubule-organizing Center Small GTPases. Feb, 2018 | Pubmed ID: 29457987 Imaging the Interactions Between B Cells and Antigen-Presenting Cells Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29388105 The Interaction of Sex, Height, and QRS Duration on the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality: an Individual-patient Data Meta-analysis European Journal of Heart Failure. Jan, 2018 | Pubmed ID: 29314424 Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials Circulation. Heart Failure. Oct, 2017 | Pubmed ID: 29038172 Limitations of Qdot Labelling Compared to Directly-conjugated Probes for Single Particle Tracking of B Cell Receptor Mobility Scientific Reports. Sep, 2017 | Pubmed ID: 28900238 Predictors of Short-term Clinical Response to Cardiac Resynchronization Therapy European Journal of Heart Failure. Aug, 2017 | Pubmed ID: 28295869 The Rap1-cofilin-1 Pathway Coordinates Actin Reorganization and MTOC Polarization at the B Cell Immune Synapse Journal of Cell Science. 03, 2017 | Pubmed ID: 28167682 Applied Stretch Initiates Directional Invasion Through the Action of Rap1 GTPase As a Tension Sensor Journal of Cell Science. 01, 2017 | Pubmed ID: 27199371 What Goes Up Must Come Down: A Tripartite Dok-3/Grb2/SHIP1 Inhibitory Module Limits BCR Signaling European Journal of Immunology. Nov, 2016 | Pubmed ID: 27813071 SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling Developmental Cell. Apr, 2016 | Pubmed ID: 27046831 The Paracaspase MALT1 Cleaves HOIL1 Reducing Linear Ubiquitination by LUBAC to Dampen Lymphocyte NF-κB Signalling Nature Communications. Nov, 2015 | Pubmed ID: 26525107 Toll-like Receptor Ligands Sensitize B-cell Receptor Signalling by Reducing Actin-dependent Spatial Confinement of the Receptor Nature Communications. Feb, 2015 | Pubmed ID: 25644899 PI3K Signaling in B Cell and T Cell Biology Frontiers in Immunology. 2014 | Pubmed ID: 25404931 An Individual Patient Meta-analysis of Five Randomized Trials Assessing the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality in Patients with Symptomatic Heart Failure European Heart Journal. Dec, 2013 | Pubmed ID: 23900696 Control of the Hippo Pathway by Set7-dependent Methylation of Yap Developmental Cell. Jul, 2013 | Pubmed ID: 23850191 The Invasion Inhibitor Sarasinoside A1 Reverses Mesenchymal Tumor Transformation in an E-cadherin-independent Manner Molecular Cancer Research : MCR. May, 2013 | Pubmed ID: 23399642 Selective Pharmacological Inhibition of Phosphoinositide 3-kinase P110delta Opposes the Progression of Autoimmune Diabetes in Non-obese Diabetic (NOD) Mice Autoimmunity. Feb, 2013 | Pubmed ID: 23039284 Small Molecule Inhibitors of the Pyk2 and FAK Kinases Modulate Chemoattractant-induced Migration, Adhesion and Akt Activation in Follicular and Marginal Zone B Cells Cellular Immunology. Jan-Feb, 2012 | Pubmed ID: 22507871 Cofilin-mediated F-actin Severing is Regulated by the Rap GTPase and Controls the Cytoskeletal Dynamics That Drive Lymphocyte Spreading and BCR Microcluster Formation Journal of Immunology (Baltimore, Md. : 1950). Dec, 2011 | Pubmed ID: 22068232 Opposing Roles for CD34 in B16 Melanoma Tumor Growth Alter Early Stage Vasculature and Late Stage Immune Cell Infiltration PloS One. Apr, 2011 | Pubmed ID: 21494591 TNFR1 Delivers Pro-survival Signals That Are Required for Limiting TNFR2-dependent Activation-induced Cell Death (AICD) in CD8+ T Cells European Journal of Immunology. Feb, 2011 | Pubmed ID: 21268004 Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the Lungs Cancer Research. Jun, 2010 | Pubmed ID: 20484042 Rap GTPase-mediated Adhesion and Migration: A Target for Limiting the Dissemination of B-cell Lymphomas? Cell Adhesion & Migration. Jul-Sep, 2010 | Pubmed ID: 20212359 Phosphoinositide 3-kinase P110 Delta Regulates Natural Antibody Production, Marginal Zone and B-1 B Cell Function, and Autoantibody Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2009 | Pubmed ID: 19843950 Localized Diacylglycerol-dependent Stimulation of Ras and Rap1 During Phagocytosis The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19700408 B Cell Receptor-induced Phosphorylation of Pyk2 and Focal Adhesion Kinase Involves Integrins and the Rap GTPases and is Required for B Cell Spreading The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19561089 Lymphocytes in the Peritoneum Home to the Omentum and Are Activated by Resident Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19553538 B Cell Development: Important Work for ERK Immunity. Apr, 2008 | Pubmed ID: 18400191 The Rap GTPases Regulate B Cell Morphology, Immune-synapse Formation, and Signaling by Particulate B Cell Receptor Ligands Immunity. Jan, 2008 | Pubmed ID: 18191594 Differential Role of Reactive Oxygen Species in the Activation of Mitogen-activated Protein Kinases and Akt by Key Receptors on B-lymphocytes: CD40, the B Cell Antigen Receptor, and CXCR4 Journal of Cell Communication and Signaling. Jun, 2007 | Pubmed ID: 18481208 The Rap GTPases Mediate CXCL13- and Sphingosine1-phosphate-induced Chemotaxis, Adhesion, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes European Journal of Immunology. Aug, 2006 | Pubmed ID: 16821235 The Rap GTPases Regulate Integrin-mediated Adhesion, Cell Spreading, Actin Polymerization, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14701796 Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12904304 Akt is TCL-ish: Implications for B-cell Lymphoma Trends in Immunology. Mar, 2003 | Pubmed ID: 12615201 The Human Antimicrobial Peptide LL-37 is a Multifunctional Modulator of Innate Immune Responses Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244186 The Rap GTPases Regulate B Cell Migration Toward the Chemokine Stromal Cell-derived Factor-1 (CXCL12): Potential Role for Rap2 in Promoting B Cell Migration Journal of Immunology (Baltimore, Md. : 1950). Aug, 2002 | Pubmed ID: 12133960 To Make Antibodies or Not: Signaling by the B-cell Antigen Receptor Trends in Pharmacological Sciences. Jul, 2002 | Pubmed ID: 12119152 The B Cell Antigen Receptor Regulates the Transcriptional Activator Beta-catenin Via Protein Kinase C-mediated Inhibition of Glycogen Synthase Kinase-3 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002 | Pubmed ID: 12097378 Activation and Phosphatidylinositol 3-kinase-dependent Phosphorylation of Protein Kinase C-epsilon by the B Cell Antigen Receptor Immunology Letters. Jul, 2002 | Pubmed ID: 12036603 The Direct Recruitment of BLNK to Immunoglobulin Alpha Couples the B-cell Antigen Receptor to Distal Signaling Pathways Molecular and Cellular Biology. Apr, 2002 | Pubmed ID: 11909947 CD40 Signaling in B Cells Regulates the Expression of the Pim-1 Kinase Via the NF-kappa B Pathway Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777968 Interaction of Cationic Peptides with Lipoteichoic Acid and Gram-positive Bacteria Infection and Immunity. Dec, 1999 | Pubmed ID: 10569762 Dendritic Cell Survival and Maturation Are Regulated by Different Signaling Pathways The Journal of Experimental Medicine. Dec, 1998 | Pubmed ID: 9841930 Listeria Monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-activated Protein Kinase Pathway Infection and Immunity. Mar, 1998 | Pubmed ID: 9488402 बी सेल प्रतिरक्षा Synapse में Actin और Microtubule Cytoskeletons visualizing प्रेरित उत्सर्जन घट (STED) माइक्रोस्कोपी का उपयोग Jia C. Wang1, Madison Bolger-Munro1, Michael R. Gold1 1Department of Microbiology and Immunology, University of British Columbia JoVE 57028 Immunology and Infection
बी सेल प्रतिरक्षा Synapse में Actin और Microtubule Cytoskeletons visualizing प्रेरित उत्सर्जन घट (STED) माइक्रोस्कोपी का उपयोग Jia C. Wang1, Madison Bolger-Munro1, Michael R. Gold1 1Department of Microbiology and Immunology, University of British Columbia JoVE 57028 Immunology and Infection