Michael Hornsby The Recombinant Antibody Network Biography Publications Institution JoVE Articles Michael Hornsby has not added a biography. If you are Michael Hornsby and would like to personalize this page please email our Author Liaison for assistance. Publications An Improved Single-Chain Fab Platform for Efficient Display and Recombinant Expression Journal of Molecular Biology. Dec, 2014 | Pubmed ID: 25481745 Evidence of Convergent Evolution in Humans and Macaques Supports an Adaptive Role for Copy Number Variation of the β-defensin-2 Gene Genome Biology and Evolution. 2014 | Pubmed ID: 25349268 Lipocalin-2 Resistance Confers an Advantage to Salmonella Enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine Cell Host & Microbe. May, 2009 | Pubmed ID: 19454351 Active Site Conformational Changes of Prostasin Provide a New Mechanism of Protease Regulation by Divalent Cations Protein Science : a Publication of the Protein Society. May, 2009 | Pubmed ID: 19388054 Helicobacter Pylori Induces an Antimicrobial Response in Rhesus Macaques in a Cag Pathogenicity Island-dependent Manner Gastroenterology. Apr, 2008 | Pubmed ID: 18395086 Crystal Structure of Human Pus10, a Novel Pseudouridine Synthase Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17900615 Characterization and Optimization of Selective, Nonpeptidic Inhibitors of Cathepsin S with an Unprecedented Binding Mode Journal of Medicinal Chemistry. May, 2007 | Pubmed ID: 17469812 Identification of Selective, Nonpeptidic Nitrile Inhibitors of Cathepsin S Using the Substrate Activity Screening Method Journal of Medicinal Chemistry. Oct, 2006 | Pubmed ID: 17034136 Synthesis and SAR of Arylaminoethyl Amides As Noncovalent Inhibitors of Cathepsin S: P3 Cyclic Ethers Bioorganic & Medicinal Chemistry Letters. Oct, 2006 | Pubmed ID: 16876402 Crystal Structure of Acireductone Dioxygenase (ARD) from Mus Musculus at 2.06 Angstrom Resolution Proteins. Aug, 2006 | Pubmed ID: 16783794 Crystal Structure of TM1367 from Thermotoga Maritima at 1.90 A Resolution Reveals an Atypical Member of the Cyclophilin (peptidylprolyl Isomerase) Fold Proteins. Jun, 2006 | Pubmed ID: 16544291 Crystal Structure of a Single-stranded DNA-binding Protein (TM0604) from Thermotoga Maritima at 2.60 A Resolution Proteins. Apr, 2006 | Pubmed ID: 16435371 Crystal Structure of Virulence Factor CJ0248 from Campylobacter Jejuni at 2.25 A Resolution Reveals a New Fold Proteins. Jan, 2006 | Pubmed ID: 16287129 Crystal Structure of a Conserved Hypothetical Protein (gi: 13879369) from Mouse at 1.90 A Resolution Reveals a New Fold Proteins. Dec, 2005 | Pubmed ID: 16224779 Identification of Coumarin Derivatives As a Novel Class of Allosteric MEK1 Inhibitors Bioorganic & Medicinal Chemistry Letters. Dec, 2005 | Pubmed ID: 16199156 Crystal Structure of Hsp33 Chaperone (TM1394) from Thermotoga Maritima at 2.20 A Resolution Proteins. Nov, 2005 | Pubmed ID: 16167343 Crystal Structure of a Putative Modulator of DNA Gyrase (pmbA) from Thermotoga Maritima at 1.95 A Resolution Reveals a New Fold Proteins. Nov, 2005 | Pubmed ID: 16104019 Crystal Structure of the Global Regulatory Protein CsrA from Pseudomonas Putida at 2.05 A Resolution Reveals a New Fold Proteins. Nov, 2005 | Pubmed ID: 16104018 Crystal Structure of an Apo MRNA Decapping Enzyme (DcpS) from Mouse at 1.83 A Resolution Proteins. Sep, 2005 | Pubmed ID: 16001405 Crystal Structure of S-adenosylmethionine:tRNA Ribosyltransferase-isomerase (QueA) from Thermotoga Maritima at 2.0 A Resolution Reveals a New Fold Proteins. Jun, 2005 | Pubmed ID: 15822125 Crystal Structure of an Indigoidine Synthase A (IndA)-like Protein (TM1464) from Thermotoga Maritima at 1.90 A Resolution Reveals a New Fold Proteins. Jun, 2005 | Pubmed ID: 15822122 Crystal Structure of an Alanine-glyoxylate Aminotransferase from Anabaena Sp. at 1.70 A Resolution Reveals a Noncovalently Linked PLP Cofactor Proteins. Mar, 2005 | Pubmed ID: 15657930 Crystal Structure of a Formiminotetrahydrofolate Cyclodeaminase (TM1560) from Thermotoga Maritima at 2.80 A Resolution Reveals a New Fold Proteins. Mar, 2005 | Pubmed ID: 15651027 Crystal Structure of an Alpha/beta Serine Hydrolase (YDR428C) from Saccharomyces Cerevisiae at 1.85 A Resolution Proteins. Feb, 2005 | Pubmed ID: 15624212 Selecção de alta Scalable Rendimento de bibliotecas de anticorpos em fagos sintética exibida- Shane Miersch1,2, Zhijian Li1,2, Rachel Hanna1,2, Megan E. McLaughlin1,2, Michael Hornsby1,3, Tet Matsuguchi1,3, Marcin Paduch1,4, Annika Sääf1,4, Jim Wells1,3, Shohei Koide1,4, Anthony Kossiakoff1,4, Sachdev S. Sidhu1,2 1The Recombinant Antibody Network, 2The Banting and Best Department of Medical Research, University of Toronto, 3Antibiome Center, University of California, San Francisco at Mission Bay, 4Department of Biochemistry and Molecular Biology, The University of Chicago JoVE 51492 Immunology and Infection
Selecção de alta Scalable Rendimento de bibliotecas de anticorpos em fagos sintética exibida- Shane Miersch1,2, Zhijian Li1,2, Rachel Hanna1,2, Megan E. McLaughlin1,2, Michael Hornsby1,3, Tet Matsuguchi1,3, Marcin Paduch1,4, Annika Sääf1,4, Jim Wells1,3, Shohei Koide1,4, Anthony Kossiakoff1,4, Sachdev S. Sidhu1,2 1The Recombinant Antibody Network, 2The Banting and Best Department of Medical Research, University of Toronto, 3Antibiome Center, University of California, San Francisco at Mission Bay, 4Department of Biochemistry and Molecular Biology, The University of Chicago JoVE 51492 Immunology and Infection