Mike D. Blower Department of Molecular Biology Massachusetts General Hospital Biography Publications Institution JoVE Articles Mike D. Blower has not added a biography. If you are Mike D. Blower and would like to personalize this page please email our Author Liaison for assistance. Publications Bacillus Anthracis Co-opts Nitric Oxide and Host Serum Albumin for Pathogenicity in Hypoxic Conditions Frontiers in Cellular and Infection Microbiology. 2013 | Pubmed ID: 23730627 The Complete Mitochondrial Genome of the Dusky Shark Carcharhinus Obscurus Mitochondrial DNA. Apr, 2013 | Pubmed ID: 23551174 IgG4 Subclass Antibodies Impair Antitumor Immunity in Melanoma The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23454746 Surface Behavior of Malonic Acid Adsorption at the Air/water Interface The Journal of Physical Chemistry. A. Mar, 2013 | Pubmed ID: 23384061 Molecular Insights into Intracellular RNA Localization International Review of Cell and Molecular Biology. 2013 | Pubmed ID: 23351709 Selectivity and Self-assembly in the Control of a Bacterial Toxin by an Antitoxic Noncoding RNA Pseudoknot Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23267117 An Integrated View of Data Quality in Earth Observation Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Jan, 2013 | Pubmed ID: 23230156 Bisphosphonate-anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging ACS Nano. Jan, 2013 | Pubmed ID: 23194247 Incorporation of Paramagnetic, Fluorescent and PET/SPECT Contrast Agents into Liposomes for Multimodal Imaging Biomaterials. Jan, 2013 | Pubmed ID: 23131536 P53-dependent Radiobiological Responses to Internalised Indium-111 in Human Cells Nuclear Medicine and Biology. Jan, 2013 | Pubmed ID: 23062949 Viral Molecular Mimicry Circumvents Abortive Infection and Suppresses Bacterial Suicide to Make Hosts Permissive for Replication Bacteriophage. Oct, 2012 | Pubmed ID: 23739522 Viral Evasion of a Bacterial Suicide System by RNA-based Molecular Mimicry Enables Infectious Altruism PLoS Genetics. 2012 | Pubmed ID: 23109916 Universal Access to HIV Treatment Versus Universal 'test and Treat': Transmission, Drug Resistance & Treatment Costs PloS One. 2012 | Pubmed ID: 22957012 Dithiocarbamate Complexes As Radiopharmaceuticals for Medical Imaging Mini Reviews in Medicinal Chemistry. Oct, 2012 | Pubmed ID: 22931590 A Feasibility Analysis of Implementing Interventions for Discordant Couples in 14 African Countries: Implications for Epidemic Control AIDS (London, England). Sep, 2012 | Pubmed ID: 22824631 Predicting Effect of Pre-exposure Prophylaxis on HIV Epidemics Lancet. Jun, 2012 | Pubmed ID: 22748579 [Re(CO)(3)](+) Labelling of a Novel Cysteine/hexahistidine Tag: Insights into Binding Mode by Liquid Chromatography-mass Spectrometry Journal of Inorganic Biochemistry. Sep, 2012 | Pubmed ID: 22687562 What Impact Will Reducing Concurrency Have on Decreasing the Incidence of HIV in Heterosexual Populations? Sexually Transmitted Diseases. Jun, 2012 | Pubmed ID: 22588465 A Review of the Application of Molecular Genetics for Fisheries Management and Conservation of Sharks and Rays Journal of Fish Biology. Apr, 2012 | Pubmed ID: 22497408 Comparison of (64)Cu-Complexing Bifunctional Chelators for Radioimmunoconjugation: Labeling Efficiency, Specific Activity, and in Vitro/in Vivo Stability Bioconjugate Chemistry. Apr, 2012 | Pubmed ID: 22471317 Identification and Classification of Bacterial Type III Toxin-antitoxin Systems Encoded in Chromosomal and Plasmid Genomes Nucleic Acids Research. Jul, 2012 | Pubmed ID: 22434880 Factors Limiting the Transmission of HIV Mutations Conferring Drug Resistance: Fitness Costs and Genetic Bottlenecks Scientific Reports. 2012 | Pubmed ID: 22432052 A Promiscuous Antitoxin of Bacteriophage T4 Ensures Successful Viral Replication Molecular Microbiology. Feb, 2012 | Pubmed ID: 22283468 Hypoxia Imaging with PET: Which Tracers and Why? Nuclear Medicine Communications. Mar, 2012 | Pubmed ID: 22146595 Recombinant IgE Antibodies for Passive Immunotherapy of Solid Tumours: from Concept Towards Clinical Application Cancer Immunology, Immunotherapy : CII. Sep, 2012 | Pubmed ID: 22139135 Building PET Research Collaborations Nuclear Medicine Communications. Jan, 2012 | Pubmed ID: 21946618 A Multiscale Parallel Computing Architecture for Automated Segmentation of the Brain Connectome IEEE Transactions on Bio-medical Engineering. Jan, 2012 | Pubmed ID: 21926011 Modeling Dynamic Interactions Between Pre-exposure Prophylaxis Interventions & Treatment Programs: Predicting HIV Transmission & Resistance Scientific Reports. 2011 | Pubmed ID: 22355700 In Vivo SPECT Reporter Gene Imaging of Regulatory T Cells PloS One. 2011 | Pubmed ID: 22043296 Modeling the Impact on the HIV Epidemic of Treating Discordant Couples with Antiretrovirals to Prevent Transmission AIDS (London, England). Nov, 2011 | Pubmed ID: 21993304 National Electrical Manufacturers Association NU-4 Performance Evaluation of the PET Component of the NanoPET/CT Preclinical PET/CT Scanner Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2011 | Pubmed ID: 21969357 Functional Analysis of the Microtubule-interacting Transcriptome Molecular Biology of the Cell. Nov, 2011 | Pubmed ID: 21937723 Human Papillomavirus Vaccination Programs and Human Immunodeficiency Virus Epidemics Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Oct, 2011 | Pubmed ID: 21921228 Radiochemical Purity Testing of 99mTc-labelled Radiopharmaceuticals: How Much is Enough? Nuclear Medicine Communications. Sep, 2011 | Pubmed ID: 21799366 PET Imaging of Cardiac Hypoxia: Opportunities and Challenges Journal of Molecular and Cellular Cardiology. Nov, 2011 | Pubmed ID: 21781973 The Importance of Including Dynamic Social Networks when Modeling Epidemics of Airborne Infections: Does Increasing Complexity Increase Accuracy? BMC Medicine. 2011 | Pubmed ID: 21771292 Macrobicyclic Cage Amine Ligands for Copper Radiopharmaceuticals: a Single Bivalent Cage Amine Containing Two Lys3-bombesin Targeting Peptides Inorganic Chemistry. Jul, 2011 | Pubmed ID: 21667932 Efficient Bifunctional Gallium-68 Chelators for Positron Emission Tomography: Tris(hydroxypyridinone) Ligands Chemical Communications (Cambridge, England). Jul, 2011 | Pubmed ID: 21623436 MTOR Phosphorylates IMP2 to Promote IGF2 MRNA Translation by Internal Ribosomal Entry Genes & Development. Jun, 2011 | Pubmed ID: 21576258 Harnessing Engineered Antibodies of the IgE Class to Combat Malignancy: Initial Assessment of FcÉ›RI-mediated Basophil Activation by a Tumour-specific IgE Antibody to Evaluate the Risk of Type I Hypersensitivity Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Oct, 2011 | Pubmed ID: 21569129 Monitoring the Systemic Human Memory B Cell Compartment of Melanoma Patients for Anti-tumor IgG Antibodies PloS One. 2011 | Pubmed ID: 21559411 Synthesis of 64Cu(II)-bis(dithiocarbamatebisphosphonate) and Its Conjugation with Superparamagnetic Iron Oxide Nanoparticles: in Vivo Evaluation As Dual-modality PET-MRI Agent Angewandte Chemie (International Ed. in English). Jun, 2011 | Pubmed ID: 21544908 Could We – Should We – Calculate a Risk Exposure Score for an HIV-negative Individual in a Serodiscordant Couple? AIDS (London, England). May, 2011 | Pubmed ID: 21537115 Inorganic Approaches for Radiolabelling Biomolecules with Fluorine-18 for Imaging with Positron Emission Tomography Dalton Transactions (Cambridge, England : 2003). Jun, 2011 | Pubmed ID: 21499604 Quantification of the Role of Discordant Couples in Driving Incidence of HIV in Sub-Saharan Africa The Lancet Infectious Diseases. Apr, 2011 | Pubmed ID: 21453868 Biocompatible Inorganic Nanoparticles for [18F]-fluoride Binding with Applications in PET Imaging Dalton Transactions (Cambridge, England : 2003). Jun, 2011 | Pubmed ID: 21394352 Synthesis and Evaluation of Analogues of HYNIC As Bifunctional Chelators for Technetium Dalton Transactions (Cambridge, England : 2003). Jun, 2011 | Pubmed ID: 21350776 (â¹â¹m)Tc-bisphosphonate-iron Oxide Nanoparticle Conjugates for Dual-modality Biomedical Imaging Bioconjugate Chemistry. Mar, 2011 | Pubmed ID: 21338098 Balancing at Survival's Edge: the Structure and Adaptive Benefits of Prokaryotic Toxin-antitoxin Partners Current Opinion in Structural Biology. Feb, 2011 | Pubmed ID: 21315267 A Processed Noncoding RNA Regulates an Altruistic Bacterial Antiviral System Nature Structural & Molecular Biology. Feb, 2011 | Pubmed ID: 21240270 SPECT/CT Lymphoscintigraphy of Heterotopic Cardiac Grafts Reveals Novel Sites of Lymphatic Drainage and T Cell Priming American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Feb, 2011 | Pubmed ID: 21219574 Synthesis of Porous Hollow Silica Nanostructures Using Hydroxyapatite Nanoparticle Templates Chemical Communications (Cambridge, England). Feb, 2011 | Pubmed ID: 21116531 Evaluation of [18F]-tetrafluoroborate As a Potential PET Imaging Agent for the Human Sodium/iodide Symporter in a New Colon Carcinoma Cell Line, HCT116, Expressing HNIS Nuclear Medicine Communications. Feb, 2011 | Pubmed ID: 21085047 Assessing the Impact of Mass Rape on the Incidence of HIV in Conflict-affected Countries AIDS (London, England). Nov, 2010 | Pubmed ID: 20859191 Costs of Eliminating HIV in South Africa Have Been Underestimated Lancet. Sep, 2010 | Pubmed ID: 20851250 HIV, Transmitted Drug Resistance, and the Paradox of Preexposure Prophylaxis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20616092 Synthesis and Biological Evaluation of [(18)F]tetrafluoroborate: a PET Imaging Agent for Thyroid Disease and Reporter Gene Imaging of the Sodium/iodide Symporter European Journal of Nuclear Medicine and Molecular Imaging. Nov, 2010 | Pubmed ID: 20577737 Predicting the Level of Vaccine-induced Cross-immunity Necessary to Eliminate HIV Epidemics Composed of Multiple Subtypes AIDS (London, England). Jun, 2010 | Pubmed ID: 20539095 188Re(CO)3-dipicolylamine-alendronate: a New Bisphosphonate Conjugate for the Radiotherapy of Bone Metastases Bioconjugate Chemistry. May, 2010 | Pubmed ID: 20387897 A Universal Long-term Flu Vaccine May Not Prevent Severe Epidemics BMC Research Notes. 2010 | Pubmed ID: 20367882 A Major HIV Risk Factor for Young Men Who Have Sex with Men is Sex with Older Partners Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2010 | Pubmed ID: 20335817 Should We Try to Eliminate HIV Epidemics by Using a 'Test and Treat' Strategy? AIDS (London, England). Mar, 2010 | Pubmed ID: 20177359 Evolutionary Dynamics of Complex Networks of HIV Drug-resistant Strains: the Case of San Francisco Science (New York, N.Y.). Feb, 2010 | Pubmed ID: 20075214 Are Correctional Facilities Amplifying the Epidemic of Community-acquired Methicillin-resistant Staphylococcus Aureus? Nature Reviews. Microbiology. Jan, 2010 | Pubmed ID: 20010953 Pharmacogenomic Approach Reveals a Role for the X(c)- Cystine/glutamate Antiporter in Growth and Celastrol Resistance of Glioma Cell Lines The Journal of Pharmacology and Experimental Therapeutics. Mar, 2010 | Pubmed ID: 20007406 Radiobiological Effects of Hypoxia-dependent Uptake of 64Cu-ATSM: Enhanced DNA Damage and Cytotoxicity in Hypoxic Cells European Journal of Nuclear Medicine and Molecular Imaging. Feb, 2010 | Pubmed ID: 19915836 Calculating the Potential for Within-flight Transmission of Influenza A (H1N1) BMC Medicine. 2009 | Pubmed ID: 20034378 A Broadly Conserved Pathway Generates 3'UTR-directed Primary PiRNAs Current Biology : CB. Dec, 2009 | Pubmed ID: 20022248 Quantifying the Treatment Efficacy of Reverse Transcriptase Inhibitors: New Analyses of Clinical Data Based on Within-host Modeling BMC Public Health. 2009 | Pubmed ID: 19922681 Efficient Site-specific Radiolabeling of a Modified C2A Domain of Synaptotagmin I with [99mTc(CO)3]+: a New Radiopharmaceutical for Imaging Cell Death Bioconjugate Chemistry. Nov, 2009 | Pubmed ID: 19874007 Nuclear Imaging of Molecular Processes in Cancer Targeted Oncology. Sep, 2009 | Pubmed ID: 19779864 Systematic and Single Cell Analysis of Xenopus Piwi-interacting RNAs and Xiwi The EMBO Journal. Oct, 2009 | Pubmed ID: 19713941 Bifunctional Bisphosphonate Complexes for the Diagnosis and Therapy of Bone Metastases Chemical Communications (Cambridge, England). Aug, 2009 | Pubmed ID: 19652801 Mutagenesis and Functional Characterization of the RNA and Protein Components of the ToxIN Abortive Infection and Toxin-antitoxin Locus of Erwinia Journal of Bacteriology. Oct, 2009 | Pubmed ID: 19633081 Modeling Influenza Epidemics and Pandemics: Insights into the Future of Swine Flu (H1N1) BMC Medicine. 2009 | Pubmed ID: 19545404 Technetium-binding in Labelled HYNIC-peptide Conjugates: Role of Coordinating Amino Acids Journal of Inorganic Biochemistry. Jul, 2009 | Pubmed ID: 19447500 99mTc-HYNIC-Gastrin Peptides: Assisted Coordination of 99mTc by Amino Acid Side Chains Results in Improved Performance Both In Vitro and In Vivo Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2009 | Pubmed ID: 19289435 The Phage Abortive Infection System, ToxIN, Functions As a Protein-RNA Toxin-antitoxin Pair Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19124776 Running Climate Models on Grids Using G-Rex Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Mar, 2009 | Pubmed ID: 19087943 GODIVA2: Interactive Visualization of Environmental Data on the Web Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. Mar, 2009 | Pubmed ID: 19087942 Pharmacogenomics Approach Reveals MRP1 (ABCC1)-mediated Resistance to Geldanamycins Pharmaceutical Research. Apr, 2009 | Pubmed ID: 19067123 Acceptability and Repeatability of Spirometry in Children Using Updated ATS/ERS Criteria Pediatric Pulmonology. Oct, 2008 | Pubmed ID: 18785259 Is There Any Evidence That Syphilis Epidemics Cycle? The Lancet Infectious Diseases. Sep, 2008 | Pubmed ID: 18718441 The Paradoxical Effects of Using Antiretroviral-based Microbicides to Control HIV Epidemics Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18606986 In Vitro Differential Sensitivity of Melanomas to Phenothiazines is Based on the Presence of Codon 600 BRAF Mutation Molecular Cancer Therapeutics. Jun, 2008 | Pubmed ID: 18524847 A Technetium Intermediate Specifically Promotes Deprotection of Trifluoroacetyl HYNIC During Radiolabelling Under Mild Conditions Dalton Transactions (Cambridge, England : 2003). Jun, 2008 | Pubmed ID: 18493625 Infectious Syphilis in High-income Settings in the 21st Century The Lancet Infectious Diseases. Apr, 2008 | Pubmed ID: 18353265 MicroRNAs Modulate the Chemosensitivity of Tumor Cells Molecular Cancer Therapeutics. Jan, 2008 | Pubmed ID: 18187804 Genome-wide Analysis Demonstrates Conserved Localization of Messenger RNAs to Mitotic Microtubules The Journal of Cell Biology. Dec, 2007 | Pubmed ID: 18166649 Effects of Atmospherically Important Solvated Ions on Organic Acid Adsorption at the Surface of Aqueous Solutions The Journal of Physical Chemistry. B. Dec, 2007 | Pubmed ID: 18004833 How Do HYNIC-conjugated Peptides Bind Technetium? Insights from LC-MS and Stability Studies Dalton Transactions (Cambridge, England : 2003). Nov, 2007 | Pubmed ID: 17992285 Mean-field Analysis of an Inductive Reasoning Game: Application to Influenza Vaccination Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Sep, 2007 | Pubmed ID: 17930219 Effectiveness and Efficiency of Imperfect Therapeutic HSV-2 Vaccines Human Vaccines. Nov-Dec, 2007 | Pubmed ID: 17881889 Cystine-glutamate Transporter SLC7A11 Mediates Resistance to Geldanamycin but Not to 17-(allylamino)-17-demethoxygeldanamycin Molecular Pharmacology. Dec, 2007 | Pubmed ID: 17875604 Modelling an Outbreak of an Emerging Pathogen Nature Reviews. Microbiology. Sep, 2007 | Pubmed ID: 17703226 Predicting the Future of XDR Tuberculosis The Lancet Infectious Diseases. Jul, 2007 | Pubmed ID: 17597567 How Far Will We Need to Go to Reach HIV-infected People in Rural South Africa? BMC Medicine. 2007 | Pubmed ID: 17577418 MicroRNA Expression Profiles for the NCI-60 Cancer Cell Panel Molecular Cancer Therapeutics. May, 2007 | Pubmed ID: 17483436 Can Influenza Epidemics Be Prevented by Voluntary Vaccination? PLoS Computational Biology. May, 2007 | Pubmed ID: 17480117 Longitudinal Study of Herpes Simplex Virus Type 2 Infection Using Viral Dynamic Modelling Sexually Transmitted Infections. Aug, 2007 | Pubmed ID: 17475687 Chemogenomic Analysis Identifies Geldanamycins As Substrates and Inhibitors of ABCB1 Pharmaceutical Research. Sep, 2007 | Pubmed ID: 17457659 Narrative Review: Antiretroviral Therapy to Prevent the Sexual Transmission of HIV-1 Annals of Internal Medicine. Apr, 2007 | Pubmed ID: 17438318 Nonlinear Vibrational Spectroscopic Studies of the Adsorption and Speciation of Nitric Acid at the Vapor/acid Solution Interface The Journal of Physical Chemistry. A. May, 2007 | Pubmed ID: 17419597 Chemoinformatics Analysis Identifies Cytotoxic Compounds Susceptible to Chemoresistance Mediated by Glutathione and Cystine/glutamate Transport System Xc- Journal of Medicinal Chemistry. Apr, 2007 | Pubmed ID: 17367118 Theory Versus Data: How to Calculate R0? PloS One. 2007 | Pubmed ID: 17356693 Xenopus Tropicalis Egg Extracts Provide Insight into Scaling of the Mitotic Spindle The Journal of Cell Biology. Mar, 2007 | Pubmed ID: 17339377 Trifluoroacetyl-HYNIC Peptides: Synthesis and 99mTc Radiolabeling Journal of Medicinal Chemistry. Mar, 2007 | Pubmed ID: 17315986 The Emergence of HIV Transmitted Resistance in Botswana: "when Will the WHO Detection Threshold Be Exceeded?" PloS One. 2007 | Pubmed ID: 17225857 Modeling the Potential Impact of Rectal Microbicides to Reduce Hiv Transmission in Bathhouses Mathematical Biosciences and Engineering : MBE. Jul, 2006 | Pubmed ID: 20210374 Predicting the Epidemiological Impact of Antiretroviral Allocation Strategies in KwaZulu-Natal: the Effect of the Urban-rural Divide Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16968786 Drosophila CENP-A Mutations Cause a BubR1-dependent Early Mitotic Delay Without Normal Localization of Kinetochore Components PLoS Genetics. Jul, 2006 | Pubmed ID: 16839185 Views of Child Psychiatrists on Physical Contact with Patients The British Journal of Psychiatry : the Journal of Mental Science. May, 2006 | Pubmed ID: 16648538 Role of Parametric Resonance in Virological Failure During HIV Treatment Interruption Therapy Lancet. Apr, 2006 | Pubmed ID: 16631884 Towards Molecular Imaging and Treatment of Disease with Radionuclides: the Role of Inorganic Chemistry Dalton Transactions (Cambridge, England : 2003). Apr, 2006 | Pubmed ID: 16568178 Rational Choices for Allocating Antiretrovirals in Africa: Treatment Equity, Epidemiological Efficiency, and Feasibility PLoS Medicine. Mar, 2006 | Pubmed ID: 16563042 Mislocalization of the Drosophila Centromere-specific Histone CID Promotes Formation of Functional Ectopic Kinetochores Developmental Cell. Mar, 2006 | Pubmed ID: 16516834 Comparison of Methods for Sequential Screening of Large Compound Sets Combinatorial Chemistry & High Throughput Screening. Feb, 2006 | Pubmed ID: 16475969 Decision Tree Methods in Pharmaceutical Research Current Topics in Medicinal Chemistry. 2006 | Pubmed ID: 16454756 Linking Population-level Models with Growing Networks: a Class of Epidemic Models Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Oct, 2005 | Pubmed ID: 16383471 Response to Foss Et Al., 'Care Should Be Taken when Promoting Microbicide Use Among Sex Workers Who Are Able to Use Condoms Consistently' AIDS (London, England). Nov, 2005 | Pubmed ID: 16260916 Modeling the Potential Public Health Impact of Imperfect HIV Vaccines The Journal of Infectious Diseases. Oct, 2005 | Pubmed ID: 16170769 Expression of an Anti-CD33 Single-chain Antibody by Pichia Pastoris Journal of Immunological Methods. Oct, 2005 | Pubmed ID: 16139294 Water-soluble Phosphines for Direct Labeling of Peptides with Technetium and Rhenium: Insights from Electrospray Mass Spectrometry Bioconjugate Chemistry. Jul-Aug, 2005 | Pubmed ID: 16029035 Predicting the Potential Public Health Impact of Disease-modifying HIV Vaccines in South Africa: the Problem of Subtypes Current Drug Targets. Infectious Disorders. Jun, 2005 | Pubmed ID: 15975023 Allocating Antiretrovirals in South Africa: Using Modeling to Determine Treatment Equity PLoS Medicine. Jun, 2005 | Pubmed ID: 15971938 Grazing and Vigilance by Soay Sheep on Lundy Island: Influence of Group Size, Terrain and the Distribution of Vegetation Behavioural Processes. Sep, 2005 | Pubmed ID: 15963661 5-hydroxytryptamine Type-3 Receptor Antagonists for Chemotherapy-induced and Radiotherapy-induced Nausea and Emesis: Can We Safely Reduce the Dose of Administered Agents? Cancer. Jul, 2005 | Pubmed ID: 15929119 Drug-drug Interactions in Oncology: Why Are They Important and Can They Be Minimized? Critical Reviews in Oncology/hematology. Aug, 2005 | Pubmed ID: 15890526 The Reinfection Threshold Does Not Exist Journal of Theoretical Biology. Jul, 2005 | Pubmed ID: 15862585 A Rae1-containing Ribonucleoprotein Complex is Required for Mitotic Spindle Assembly Cell. Apr, 2005 | Pubmed ID: 15851029 Predicting the Potential Individual- and Population-level Effects of Imperfect Herpes Simplex Virus Type 2 Vaccines The Journal of Infectious Diseases. May, 2005 | Pubmed ID: 15838802 Is There a Pharmacological Basis for Differences in 5-HT3-receptor Antagonist Efficacy in Refractory Patients? Cancer Chemotherapy and Pharmacology. Sep, 2005 | Pubmed ID: 15838653 Evaluating the Potential Impact of Vaginal Microbicides to Reduce the Risk of Acquiring HIV in Female Sex Workers AIDS (London, England). Mar, 2005 | Pubmed ID: 15750395 A Queueing Model for Chronic Recurrent Conditions Under Panel Observation Biometrics. Mar, 2005 | Pubmed ID: 15737093 Designing Equitable Antiretroviral Allocation Strategies in Resource-constrained Countries PLoS Medicine. Feb, 2005 | Pubmed ID: 15737005 Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) Complexes As Hypoxia Imaging Agents Nuclear Medicine and Biology. Feb, 2005 | Pubmed ID: 15721760 Correlating Gene Expression with Chemical Scaffolds of Cytotoxic Agents: Ellipticines As Substrates and Inhibitors of MDR1 The Pharmacogenomics Journal. 2005 | Pubmed ID: 15668728 The Antiretroviral Rollout and Drug-resistant HIV in Africa: Insights from Empirical Data and Theoretical Models AIDS (London, England). Jan, 2005 | Pubmed ID: 15627028 Systematic Analysis of Large Screening Sets in Drug Discovery Current Drug Discovery Technologies. Jan, 2004 | Pubmed ID: 16472218 Microbicides: Anti-HIV Efficacy and Ethics Science (New York, N.Y.). Dec, 2004 | Pubmed ID: 15591184 Changes in the Use of Hormone Replacement Therapy in New Zealand Following the Publication of the Women's Health Initiative Trial The New Zealand Medical Journal. Nov, 2004 | Pubmed ID: 15570344 Building Predictive Models for Protein Tyrosine Phosphatase 1B Inhibitors Based on Discriminating Structural Features by Reassembling Medicinal Chemistry Building Blocks Journal of Medicinal Chemistry. Nov, 2004 | Pubmed ID: 15537353 Potential Public Health Impact of New Tuberculosis Vaccines Emerging Infectious Diseases. Sep, 2004 | Pubmed ID: 15498152 Calculating the Contribution of Herpes Simplex Virus Type 2 Epidemics to Increasing HIV Incidence: Treatment Implications Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Nov, 2004 | Pubmed ID: 15494895 Targeting Virological Core Groups: a New Paradigm for Controlling Herpes Simplex Virus Type 2 Epidemics The Journal of Infectious Diseases. Nov, 2004 | Pubmed ID: 15478066 Could Disease-modifying HIV Vaccines Cause Population-level Perversity? The Lancet Infectious Diseases. Oct, 2004 | Pubmed ID: 15451492 Modeling the Emergence of the 'hot Zones': Tuberculosis and the Amplification Dynamics of Drug Resistance Nature Medicine. Oct, 2004 | Pubmed ID: 15378053 An Attempt at a New Analysis of the Mortality Caused by Smallpox and of the Advantages of Inoculation to Prevent It. 1766 Reviews in Medical Virology. Sep-Oct, 2004 | Pubmed ID: 15334536 Modelling the Genital Herpes Epidemic Herpes : the Journal of the IHMF. Aug, 2004 | Pubmed ID: 15319083 Acf1 Confers Unique Activities to ACF/CHRAC and Promotes the Formation Rather Than Disruption of Chromatin in Vivo Genes & Development. Jan, 2004 | Pubmed ID: 14752009 Predicting the Impact of Antiretrovirals in Resource-poor Settings: Preventing HIV Infections Whilst Controlling Drug Resistance Current Drug Targets. Infectious Disorders. Dec, 2003 | Pubmed ID: 14754434 Finding Discriminating Structural Features by Reassembling Common Building Blocks Journal of Medicinal Chemistry. Oct, 2003 | Pubmed ID: 14561096 Hypoxia-targeting Copper Bis(selenosemicarbazone) Complexes: Comparison with Their Sulfur Analogues Journal of the American Chemical Society. Aug, 2003 | Pubmed ID: 12914467 Forecasting the Future of HIV Epidemics: the Impact of Antiretroviral Therapies & Imperfect Vaccines AIDS Reviews. Apr-Jun, 2003 | Pubmed ID: 12876900 Solid-phase Synthesis of Peptide Radiopharmaceuticals Using Fmoc-N-epsilon-(hynic-Boc)-lysine, a Technetium-binding Amino Acid: Application to Tc-99m-labeled Salmon Calcitonin Journal of Medicinal Chemistry. Apr, 2003 | Pubmed ID: 12699393 Predicting the Emergence of Drug-resistant HSV-2: New Predictions BMC Infectious Diseases. Mar, 2003 | Pubmed ID: 12659657 Granisetron: Relating Pharmacology to Clinical Efficacy Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Feb, 2003 | Pubmed ID: 12560937 99mTc-SnF2 Colloid "LLK": Particle Size, Morphology and Leucocyte Labelling Behaviour Nuclear Medicine Communications. Feb, 2003 | Pubmed ID: 12548044 Changes in Muscle Strength and Pain in Response to Surgical Repair of Posterior Abdominal Wall Disruption Followed by Rehabilitation British Journal of Sports Medicine. Feb, 2003 | Pubmed ID: 12547744 Predicting the Transmission of Drug-resistant HIV: Comparing Theory with Data The Lancet Infectious Diseases. Jan, 2003 | Pubmed ID: 12505024 What Can Modeling Tell Us About the Threat of Antiviral Drug Resistance? Current Opinion in Infectious Diseases. Dec, 2002 | Pubmed ID: 12821838 5-HT3-receptor Antagonists and the Cytochrome P450 System: Clinical Implications Cancer Journal (Sudbury, Mass.). Sep-Oct, 2002 | Pubmed ID: 12416899 Pharmacogenomic Analysis: Correlating Molecular Substructure Classes with Microarray Gene Expression Data The Pharmacogenomics Journal. 2002 | Pubmed ID: 12196914 Could Widespread Use of Combination Antiretroviral Therapy Eradicate HIV Epidemics? The Lancet Infectious Diseases. Aug, 2002 | Pubmed ID: 12150848 Problems and Solutions for the Stop TB Partnership The Lancet Infectious Diseases. Jun, 2002 | Pubmed ID: 12144901 Granisetron Vs Ondansetron: is It a Question of Duration of 5-HT3 Receptor Blockade? British Journal of Cancer. May, 2002 | Pubmed ID: 12085221 Multiscale and Bayesian Approaches to Data Analysis in Genomics High-throughput Screening Current Opinion in Drug Discovery & Development. May, 2002 | Pubmed ID: 12058619 Copper Bis(thiosemicarbazone) Complexes As Hypoxia Imaging Agents: Structure-activity Relationships Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Mar, 2002 | Pubmed ID: 11935349 On Combining Recursive Partitioning and Simulated Annealing to Detect Groups of Biologically Active Compounds Journal of Chemical Information and Computer Sciences. Mar-Apr, 2002 | Pubmed ID: 11911709 Studies on the Mechanism of Hypoxic Selectivity in Copper Bis(thiosemicarbazone) Radiopharmaceuticals Journal of Medicinal Chemistry. Mar, 2002 | Pubmed ID: 11906283 Conserved Organization of Centromeric Chromatin in Flies and Humans Developmental Cell. Mar, 2002 | Pubmed ID: 11879637 A Study Comparing Hyoscine Hydrobromide and Glycopyrrolate in the Treatment of Death Rattle Palliative Medicine. Jul, 2001 | Pubmed ID: 12054150 Amplification Dynamics: Predicting the Effect of HIV on Tuberculosis Outbreaks Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2001 | Pubmed ID: 11744831 Chem-tox Informatics: Data Mining Using a Medicinal Chemistry Building Block Approach Current Opinion in Drug Discovery & Development. Jan, 2001 | Pubmed ID: 11727328 Synthesis and Characterization of 111In-DTPA-N-TIMP-2: a Radiopharmaceutical for Imaging Matrix Metalloproteinase Expression Bioconjugate Chemistry. Nov-Dec, 2001 | Pubmed ID: 11716687 Transmission of Zidovudine Resistant Strains of HIV-1: the First Wave AIDS (London, England). Nov, 2001 | Pubmed ID: 11698706 Predicting the Unpredictable: Transmission of Drug-resistant HIV Nature Medicine. Sep, 2001 | Pubmed ID: 11533704 Determining Centromere Identity: Cyclical Stories and Forking Paths Nature Reviews. Genetics. Aug, 2001 | Pubmed ID: 11483983 The Role of Drosophila CID in Kinetochore Formation, Cell-cycle Progression and Heterochromatin Interactions Nature Cell Biology. Aug, 2001 | Pubmed ID: 11483958 In Vivo Evaluation of 111In-DTPA-N-TIMP-2 in Kaposi Sarcoma Associated with HIV Infection European Journal of Nuclear Medicine. Jun, 2001 | Pubmed ID: 11440037 Calculating the Consequences: HAART and Risky Sex AIDS (London, England). Jul, 2001 | Pubmed ID: 11426077 The Continuing HIV Epidemic Among Men Who Have Sex with Men American Journal of Public Health. Jun, 2001 | Pubmed ID: 11392933 Towards New Transition Metal-based Hypoxic Selective Agents for Therapy and Imaging Journal of Inorganic Biochemistry. May, 2001 | Pubmed ID: 11377691 Leprosy Research in the Post-genome Era Leprosy Review. Mar, 2001 | Pubmed ID: 11355523 Association Between the Alpha(1a) Calcium Channel Gene CACNA1A and Idiopathic Generalized Epilepsy Neurology. May, 2001 | Pubmed ID: 11342703 Live Attenuated HIV Vaccines: Predicting the Tradeoff Between Efficacy and Safety Proceedings of the National Academy of Sciences of the United States of America. Mar, 2001 | Pubmed ID: 11248127 Early Therapy for Latent Tuberculosis Infection American Journal of Epidemiology. Feb, 2001 | Pubmed ID: 11207156 Great Expectations? Parental Participation in Care Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community. 2000 | Pubmed ID: 11855401 Trithiacyclononane As a Ligand for Potential Technetium and Rhenium Radiopharmaceuticals: Synthesis of [M(9S3)(SC2H4SC2H4S)][BF4] (M = 99Tc, Re, 188Re) Via C-S Bond Cleavage Inorganic Chemistry. Sep, 2000 | Pubmed ID: 11198864 LeadScope: Software for Exploring Large Sets of Screening Data Journal of Chemical Information and Computer Sciences. Nov-Dec, 2000 | Pubmed ID: 11128088 Failure to Replicate Association Between the Gene for the Neuronal Nicotinic Acetylcholine Receptor Alpha 4 Subunit (CHRNA4) and IGE American Journal of Medical Genetics. Dec, 2000 | Pubmed ID: 11121188 99mTc(V)DMSA Quantitatively Predicts 188Re(V)DMSA Distribution in Patients with Prostate Cancer Metastatic to Bone European Journal of Nuclear Medicine. Sep, 2000 | Pubmed ID: 11007525 Oral Serotonin Type 3-receptor Antagonists for Prevention of Chemotherapy-induced Emesis American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists. Sep, 2000 | Pubmed ID: 11006796 Copper Bis(diphosphine) Complexes: Radiopharmaceuticals for the Detection of Multi-drug Resistance in Tumours by PET European Journal of Nuclear Medicine. Jun, 2000 | Pubmed ID: 10901449 Potential Impact of Tuberculosis Vaccines As Epidemic Control Agents Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jun, 2000 | Pubmed ID: 10875909 Impact of Antivirals and Emergence of Drug Resistance: HSV-2 Epidemic Control AIDS Patient Care and STDs. Mar, 2000 | Pubmed ID: 10763542 No Association Found Between Polymorphisms in Genes Encoding MGluR7 and MGluR8 and Idiopathic Generalised Epilepsy in a Case Control Study Epilepsy Research. Mar, 2000 | Pubmed ID: 10690750 A Tale of Two Futures: HIV and Antiretroviral Therapy in San Francisco Science (New York, N.Y.). Jan, 2000 | Pubmed ID: 10649998 Low-doses of Ionising Radiation Induce Melanoma Metastases and Trigger the Immune System--adrenal Axis Feedback Loop European Journal of Cancer (Oxford, England : 1990). Oct, 1999 | Pubmed ID: 10673982 Effects of Various 5-HT3 Receptor Antagonists, Granisetron, Ondansetron, Ramosetron and Azasetron on Serotonin (5-HT) Release from the Ferret Isolated Ileum Research Communications in Molecular Pathology and Pharmacology. 1999 | Pubmed ID: 10634307 Produção de Judith A. Sharp1,2, Mike D. Blower1,2 1Department of Molecular Biology, Massachusetts General Hospital, 2Department of Genetics, Harvard Medical School JoVE 50434 Biology
Produção de Judith A. Sharp1,2, Mike D. Blower1,2 1Department of Molecular Biology, Massachusetts General Hospital, 2Department of Genetics, Harvard Medical School JoVE 50434 Biology