Mila Jankovic Laboratory of Molecular Immunology The Rockefeller University Biography Publications Institution JoVE Articles Mila Jankovic has not added a biography. If you are Mila Jankovic and would like to personalize this page please email our Author Liaison for assistance. Publications Memory B Cell Responses to Omicron Subvariants After SARS-CoV-2 MRNA Breakthrough Infection in Humans The Journal of Experimental Medicine. Dec, 2022 | Pubmed ID: 36149398 Distinct Gene Expression by Expanded Clones of Quiescent Memory CD4 T cells Harboring Intact Latent HIV-1 Proviruses Cell Reports. Sep, 2022 | Pubmed ID: 36070690 Humoral Immunity to SARS-CoV-2 Elicited by Combination COVID-19 Vaccination Regimens The Journal of Experimental Medicine. Oct, 2022 | Pubmed ID: 36006380 Antibody Evolution to SARS-CoV-2 After Single-dose Ad26.COV2.S Vaccine in Humans The Journal of Experimental Medicine. Aug, 2022 | Pubmed ID: 35776090 Increased Memory B Cell Potency and Breadth After a SARS-CoV-2 MRNA Boost Nature. Jul, 2022 | Pubmed ID: 35447027 Integration Features of Intact Latent HIV-1 in CD4+ T Cell Clones Contribute to Viral Persistence The Journal of Experimental Medicine. Dec, 2021 | Pubmed ID: 34636876 Anti-SARS-CoV-2 Receptor-binding Domain Antibody Evolution After MRNA Vaccination Nature. Dec, 2021 | Pubmed ID: 34619745 Naturally Enhanced Neutralizing Breadth Against SARS-CoV-2 One Year After Infection Nature. Jul, 2021 | Pubmed ID: 34126625 Evolution of Antibody Immunity to SARS-CoV-2 Nature. Mar, 2021 | Pubmed ID: 33461210 A Combination of Human Broadly Neutralizing Antibodies Against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations Cell Host & Microbe. Aug, 2020 | Pubmed ID: 32504577 Antigen-responsive CD4+ T Cell Clones Contribute to the HIV-1 Latent Reservoir The Journal of Experimental Medicine. Jul, 2020 | Pubmed ID: 32311008 Combination Anti-HIV-1 Antibody Therapy is Associated with Increased Virus-specific T Cell Immunity Nature Medicine. Feb, 2020 | Pubmed ID: 32015556 Isolation of Single HIV-1 Envelope Specific B Cells and Antibody Cloning from Immunized Rhesus Macaques Journal of Immunological Methods. Mar, 2020 | Pubmed ID: 31866284 Combination of Quadruplex QPCR and Next-generation Sequencing for Qualitative and Quantitative Analysis of the HIV-1 Latent Reservoir The Journal of Experimental Medicine. Oct, 2019 | Pubmed ID: 31350309 HIV-specific Humoral Immune Responses by CRISPR/Cas9-edited B Cells The Journal of Experimental Medicine. Jun, 2019 | Pubmed ID: 30975893 Relationship Between Intact HIV-1 Proviruses in Circulating CD4 T Cells and Rebound Viruses Emerging During Treatment Interruption Proceedings of the National Academy of Sciences of the United States of America. Nov, 2018 | Pubmed ID: 30420517 Relationship Between Latent and Rebound Viruses in a Clinical Trial of Anti-HIV-1 Antibody 3BNC117 The Journal of Experimental Medicine. Sep, 2018 | Pubmed ID: 30072495 Clonal CD4 T Cells in the HIV-1 Latent Reservoir Display a Distinct Gene Profile Upon Reactivation Nature Medicine. May, 2018 | Pubmed ID: 29686423 The Cell Cycle Restricts Activation-induced Cytidine Deaminase Activity to Early G1 The Journal of Experimental Medicine. Jan, 2017 | Pubmed ID: 27998928 Paired Quantitative and Qualitative Assessment of the Replication-competent HIV-1 Reservoir and Comparison with Integrated Proviral DNA Proceedings of the National Academy of Sciences of the United States of America. Dec, 2016 | Pubmed ID: 27872306 Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma Cell. Aug, 2015 | Pubmed ID: 26276629 HIV-1 Integration Landscape During Latent and Active Infection Cell. Jan, 2015 | Pubmed ID: 25635456 Epigenetic Targeting of Activation-induced Cytidine Deaminase Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25512519 B Cell Super-enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity Cell. Dec, 2014 | Pubmed ID: 25483777 Identification of Chromosomal Translocation Hotspots Via Scan Statistics Bioinformatics (Oxford, England). Sep, 2014 | Pubmed ID: 24860160 T Follicular Helper Cell Dynamics in Germinal Centers Science (New York, N.Y.). Aug, 2013 | Pubmed ID: 23887872 Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching Science (New York, N.Y.). Feb, 2013 | Pubmed ID: 23306439 DNA Damage Defines Sites of Recurrent Chromosomal Translocations in B Lymphocytes Nature. Feb, 2012 | Pubmed ID: 22314321 Robust Chromosomal DNA Repair Via Alternative End-joining in the Absence of X-ray Repair Cross-complementing Protein 1 (XRCC1) Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308491 Translocation Capture Sequencing: a Method for High Throughput Mapping of Chromosomal Rearrangements Journal of Immunological Methods. Jan, 2012 | Pubmed ID: 22033343 Translocation-capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes Cell. Sep, 2011 | Pubmed ID: 21962510 Activation-induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5 Cell. Oct, 2010 | Pubmed ID: 20887897 Human Anti-HIV-neutralizing Antibodies Frequently Target a Conserved Epitope Essential for Viral Fitness The Journal of Experimental Medicine. Aug, 2010 | Pubmed ID: 20679402 PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination Science (New York, N.Y.). Aug, 2010 | Pubmed ID: 20671152 Class Switching and Meiotic Defects in Mice Lacking the E3 Ubiquitin Ligase RNF8 The Journal of Experimental Medicine. May, 2010 | Pubmed ID: 20385748 Alternative End-joining Catalyzes Class Switch Recombination in the Absence of Both Ku70 and DNA Ligase 4 The Journal of Experimental Medicine. Feb, 2010 | Pubmed ID: 20142431 Alternative End-joining Catalyzes Robust IgH Locus Deletions and Translocations in the Combined Absence of Ligase 4 and Ku70 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133803 Role of the Translocation Partner in Protection Against AID-dependent Chromosomal Translocations Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19966290 Essential Role for DNA-PKcs in DNA Double-strand Break Repair and Apoptosis in ATM-deficient Lymphocytes Molecular Cell. May, 2009 | Pubmed ID: 19450527 MicroRNA-155 Suppresses Activation-induced Cytidine Deaminase-mediated Myc-Igh Translocation Immunity. May, 2008 | Pubmed ID: 18455451 A Role for AID in Chromosome Translocations Between C-myc and the IgH Variable Region The Journal of Experimental Medicine. Sep, 2007 | Pubmed ID: 17724134 Antigen Receptor Diversification and Chromosome Translocations Nature Immunology. Aug, 2007 | Pubmed ID: 17641661 Role of Genomic Instability and P53 in AID-induced C-myc-Igh Translocations Nature. Mar, 2006 | Pubmed ID: 16400328 AID is Required for C-myc/IgH Chromosome Translocations in Vivo Cell. Aug, 2004 | Pubmed ID: 15315756 RAGs and Regulation of Autoantibodies Annual Review of Immunology. 2004 | Pubmed ID: 15032586 OcaB Regulates Transitional B Cell Selection International Immunology. Sep, 2003 | Pubmed ID: 12917262 The Cysteine-rich Domain of the Macrophage Mannose Receptor is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group Lewis(a) and Lewis(x) Types in Addition to the Sulfated N-glycans of Lutropin The Journal of Experimental Medicine. Apr, 2000 | Pubmed ID: 10748230 Gene Editing of Primary Rhesus Macaque B Cells Harald Hartweger1, Rajeev Gautam2, Yoshiaki Nishimura2, Fabian Schmidt3,5, Kai-Hui Yao1, Amelia Escolano1,6, Mila Jankovic1, Malcolm A. Martin2, Michel C. Nussenzweig1,4 1Laboratory of Molecular Immunology, The Rockefeller University, 2Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Retrovirology, The Rockefeller University, 4Howard Hughes Medical Institute, The Rockefeller University, 5Laboratory of Applied Virology and Precision Medicine, King Abdullah University of Science and Technology (KAUST), 6Vaccine and Immunotherapy Center, Wistar Institute JoVE 64858 Immunology and Infection
Gene Editing of Primary Rhesus Macaque B Cells Harald Hartweger1, Rajeev Gautam2, Yoshiaki Nishimura2, Fabian Schmidt3,5, Kai-Hui Yao1, Amelia Escolano1,6, Mila Jankovic1, Malcolm A. Martin2, Michel C. Nussenzweig1,4 1Laboratory of Molecular Immunology, The Rockefeller University, 2Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Retrovirology, The Rockefeller University, 4Howard Hughes Medical Institute, The Rockefeller University, 5Laboratory of Applied Virology and Precision Medicine, King Abdullah University of Science and Technology (KAUST), 6Vaccine and Immunotherapy Center, Wistar Institute JoVE 64858 Immunology and Infection