Natalia de las Heras Department of Physiology, Faculty of Medicine Complutense University Biography Publications Institution JoVE Articles Natalia de las Heras has not added a biography. If you are Natalia de las Heras and would like to personalize this page please email our Author Liaison for assistance. Publications Hyperdiploidy As a Rare Event That Accompanies Poor Prognosis Markers in CLL European Journal of Haematology. Sep, 2016 | Pubmed ID: 27717146 Proanthocyanidins Block Aldosterone-dependent Up-regulation of Cardiac Gamma ENaC and Nedd4-2 Inactivation Via SGK1 The Journal of Nutritional Biochemistry. Aug, 2016 | Pubmed ID: 27592201 MiRNA Expression Profile of Chronic Lymphocytic Leukemia Patients with 13q Deletion Leukemia Research. Jul, 2016 | Pubmed ID: 27111859 Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome PloS One. 2016 | Pubmed ID: 26872047 Aldosterone Induces Renal Fibrosis and Inflammatory M1-Macrophage Subtype Via Mineralocorticoid Receptor in Rats PloS One. 2016 | Pubmed ID: 26730742 Minimal Residual Disease Evaluation by Flow Cytometry is a Complementary Tool to Cytogenetics for Treatment Decisions in Acute Myeloid Leukaemia Leukemia Research. Jan, 2016 | Pubmed ID: 26598032 BRCA2 Gene Mutations and Coagulation-associated Biomarkers Thrombosis and Haemostasis. Jan, 2016 | Pubmed ID: 26446551 Management of Side Effects of BCR/ABL-negative Chronic Myeloproliferative Neoplasm Therapies. Focus on Anagrelide Expert Review of Hematology. Dec, 2015 | Pubmed ID: 26368319 Do Endothelial Cells Belong to the Primitive Stem Leukemic Clone in CML? Role of Extracellular Vesicles Leukemia Research. Aug, 2015 | Pubmed ID: 26105049 Bosutinib Shows Low Cross Intolerance, in Chronic Myeloid Leukemia Patients Treated in Fourth Line. Results of the Spanish Compassionate Use Program American Journal of Hematology. May, 2015 | Pubmed ID: 25683327 Relevance of SGK1 in Structural, Functional and Molecular Alterations Produced by Aldosterone in Heart Hormone Molecular Biology and Clinical Investigation. May, 2014 | Pubmed ID: 25390002 Beneficial Effects of Proanthocyanidins in the Cardiac Alterations Induced by Aldosterone in Rat Heart Through Mineralocorticoid Receptor Blockade PloS One. 2014 | Pubmed ID: 25353961 Antagonistic Effect of TNF-alpha and Insulin on Uncoupling Protein 2 (UCP-2) Expression and Vascular Damage Cardiovascular Diabetology. 2014 | Pubmed ID: 25077985 Carob Pod Insoluble Fiber Exerts Anti-atherosclerotic Effects in Rabbits Through Sirtuin-1 and Peroxisome Proliferator-activated Receptor-γ Coactivator-1α The Journal of Nutrition. Sep, 2014 | Pubmed ID: 25031331 [Rosuvastatin Improves Insulin Sensitivity in Overweight Rats Induced by High Fat Diet. Role of SIRT1 in Adipose Tissue] Clínica E Investigación En Arteriosclerosis : Publicación Oficial De La Sociedad Española De Arteriosclerosis. Jul-Aug, 2014 | Pubmed ID: 24612843 Protective Effect of a Pomace Olive Oil Concentrated in Triterpenic Acids in Alterations Related to Hypertension in Rats: Mechanisms Involved Molecular Nutrition & Food Research. Feb, 2014 | Pubmed ID: 24039161 Splanchnic-aortic Inflammatory Axis in Experimental Portal Hypertension World Journal of Gastroenterology. Nov, 2013 | Pubmed ID: 24307792 Vardenafil Improves Penile Erection in Type 2 Diabetes Mellitus Patients with Erectile Dysfunction: Role of Tropomyosin The Journal of Sexual Medicine. Dec, 2013 | Pubmed ID: 24112450 Pathophysiology of Vascular Remodeling in Hypertension International Journal of Hypertension. 2013 | Pubmed ID: 23970958 Prognostic Impact of the Number of Methylated Genes in Myelodysplastic Syndromes and Acute Myeloid Leukemias Treated with Azacytidine Annals of Hematology. Nov, 2013 | Pubmed ID: 23740492 Aged Garlic Extract Improves Adiponectin Levels in Subjects with Metabolic Syndrome: a Double-blind, Placebo-controlled, Randomized, Crossover Study Mediators of Inflammation. 2013 | Pubmed ID: 23533302 Analysis of the Immune System of Multiple Myeloma Patients Achieving Long-term Disease Control by Multidimensional Flow Cytometry Haematologica. Jan, 2013 | Pubmed ID: 22773604 The Risk Association Between Experimental Portal Hypertension and an Aortic Atherosclerosis-like Disease Hepatology (Baltimore, Md.). Jan, 2013 | Pubmed ID: 22730048 Changes in Cardiac Energy Metabolic Pathways in Overweighed Rats Fed a High-fat Diet European Journal of Nutrition. Mar, 2013 | Pubmed ID: 22695689 Molecular Characterization of Chronic Lymphocytic Leukemia Patients with a High Number of Losses in 13q14 PloS One. 2012 | Pubmed ID: 23152777 Incidence and Clinical Characteristics of Myeloproliferative Neoplasms Displaying a PDGFRB Rearrangement European Journal of Haematology. Jul, 2012 | Pubmed ID: 22587685 A Wound-like Inflammatory Aortic Response in Chronic Portal Hypertensive Rats Molecular Immunology. Jun, 2012 | Pubmed ID: 22463791 Spironolactone Prevents Alterations Associated with Cardiac Hypertrophy Produced by Isoproterenol in Rats: Involvement of Serum- and Glucocorticoid-regulated Kinase Type 1 Experimental Physiology. Jun, 2012 | Pubmed ID: 22327331 Brown Fat Lipoatrophy and Increased Visceral Adiposity Through a Concerted Adipocytokines Overexpression Induces Vascular Insulin Resistance and Dysfunction Endocrinology. Mar, 2012 | Pubmed ID: 22253415 Interplay of Hypertension, Inflammation, and Angiotensin II American Journal of Hypertension. Oct, 2011 | Pubmed ID: 21927010 The Clinical Utility and Prognostic Value of Multiparameter Flow Cytometry Immunophenotyping in Light-chain Amyloidosis Blood. Mar, 2011 | Pubmed ID: 21266717 Structural, Functional, and Molecular Alterations Produced by Aldosterone Plus Salt in Rat Heart: Association with Enhanced Serum and Glucocorticoid-regulated Kinase-1 Expression Journal of Cardiovascular Pharmacology. Jan, 2011 | Pubmed ID: 20980916 Rosuvastatin Restored Adrenergic and Nitrergic Function in Mesenteric Arteries from Obese Rats British Journal of Pharmacology. Jan, 2011 | Pubmed ID: 20840472 Aldosterone and the Cardiovascular System: a Dangerous Association Hormone Molecular Biology and Clinical Investigation. Dec, 2010 | Pubmed ID: 25961230 A Proteomic Approach to Determine Changes in Proteins Involved in the Myocardial Metabolism in Left Ventricles of Spontaneously Hypertensive Rats Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20110695 Risk of Progression in Smouldering Myeloma and Monoclonal Gammopathies of Unknown Significance: Comparative Analysis of the Evolution of Monoclonal Component and Multiparameter Flow Cytometry of Bone Marrow Plasma Cells British Journal of Haematology. Jan, 2010 | Pubmed ID: 19821821 The Persistence of Immunophenotypically Normal Residual Bone Marrow Plasma Cells at Diagnosis Identifies a Good Prognostic Subgroup of Symptomatic Multiple Myeloma Patients Blood. Nov, 2009 | Pubmed ID: 19755674 The Protective Effect of Irbesartan in Rats Fed a High Fat Diet is Associated with Modification of Leptin-adiponectin Imbalance Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension. Aug, 2009 | Pubmed ID: 19633450 Cardiac L-type Calcium Current is Increased in a Model of Hyperaldosteronism in the Rat Experimental Physiology. Jun, 2009 | Pubmed ID: 19395659 Soluble and Membrane Levels of Molecules Involved in the Interaction Between Clonal Plasma Cells and the Immunological Microenvironment in Multiple Myeloma and Their Association with the Characteristics of the Disease International Journal of Cancer. Jan, 2009 | Pubmed ID: 19003959 Multiparameter Flow Cytometric Remission is the Most Relevant Prognostic Factor for Multiple Myeloma Patients Who Undergo Autologous Stem Cell Transplantation Blood. Nov, 2008 | Pubmed ID: 18669875 Aldosterone and the Vascular System The Journal of Steroid Biochemistry and Molecular Biology. Apr, 2008 | Pubmed ID: 18400490 New Criteria to Identify Risk of Progression in Monoclonal Gammopathy of Uncertain Significance and Smoldering Multiple Myeloma Based on Multiparameter Flow Cytometry Analysis of Bone Marrow Plasma Cells Blood. Oct, 2007 | Pubmed ID: 17576818 Interactions Between Aldosterone and Connective Tissue Growth Factor in Vascular and Renal Damage in Spontaneously Hypertensive Rats Journal of Hypertension. Mar, 2007 | Pubmed ID: 17278980 Endothelial Dysfunction, Oxidative Stress and Inflammation in Atherosclerosis: Beneficial Effects of Statins Current Medicinal Chemistry. 2007 | Pubmed ID: 17266583 Role of Connective Tissue Growth Factor in Vascular and Renal Damage Associated with Hypertension in Rats. Interactions with Angiotensin II Journal of the Renin-angiotensin-aldosterone System : JRAAS. Dec, 2006 | Pubmed ID: 17318787 Eplerenone Reduces Oxidative Stress and Enhances ENOS in SHR: Vascular Functional and Structural Consequences Antioxidants & Redox Signaling. Sep-Oct, 2005 | Pubmed ID: 16115035 Participation of Aldosterone in the Vascular Inflammatory Response of Spontaneously Hypertensive Rats: Role of the NFkappaB/IkappaB System Journal of Hypertension. Jun, 2005 | Pubmed ID: 15894892 AT-1 Receptor Antagonism Modifies the Mediation of Endothelin-1, Thromboxane A2, and Catecholamines in the Renal Constrictor Response to Angiotensin II Kidney International. Supplement. Jan, 2005 | Pubmed ID: 15613065 Effect of AT1 Receptor Antagonism on Vascular and Circulating Inflammatory Mediators in SHR: Role of NF-kappaB/IkappaB System American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2005 | Pubmed ID: 15308481 Synergistic Effect of Angiotensin-converting Enzyme (ACE) and 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) Reductase Inhibition on Inflammatory Markers in Atherosclerotic Rabbits Clinical Science (London, England : 1979). Dec, 2003 | Pubmed ID: 12848617 Effect of AT1 Receptor Blockade on Hepatic Redox Status in SHR: Possible Relevance for Endothelial Function? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2003 | Pubmed ID: 12775556 Comparison Between the Effects of Mixed Dyslipidaemia and Hypercholesterolaemia on Endothelial Function, Atherosclerotic Lesions and Fibrinolysis in Rabbits Clinical Science (London, England : 1979). Apr, 2003 | Pubmed ID: 12653677 Role of Endothelin-1 and Thromboxane A2 in Renal Vasoconstriction Induced by Angiotensin II in Diabetes and Hypertension Kidney International. Supplement. Dec, 2002 | Pubmed ID: 12410847 Valsartan Improves Fibrinolytic Balance in Atherosclerotic Rabbits Journal of Hypertension. Feb, 2002 | Pubmed ID: 11821716 Fænotypisk karakterisering af makrofager fra rottenyre ved flowcytometri Alfonso Rubio-Navarro1, Melania Guerrero-Hue1, Beatriz Martín-Fernandez2, Isabel Cortegano3, Elena Olivares-Alvaro2, Natalia de las Heras2, Mario Alía3, Belén de Andrés3, María Luisa Gaspar3, Jesús Egido1, Juan Antonio Moreno1 1Renal, Vascular and Diabetes Research Lab, IIS-Fundaciòn Jiménez Dìaz, Autonoma University, 2Department of Physiology, Faculty of Medicine, Complutense University, 3Department of Immunology, Centro Nacional de Microbiologìa, Instituto de Salud Carlos III (ISCIII) JoVE 54599 Immunology and Infection
Fænotypisk karakterisering af makrofager fra rottenyre ved flowcytometri Alfonso Rubio-Navarro1, Melania Guerrero-Hue1, Beatriz Martín-Fernandez2, Isabel Cortegano3, Elena Olivares-Alvaro2, Natalia de las Heras2, Mario Alía3, Belén de Andrés3, María Luisa Gaspar3, Jesús Egido1, Juan Antonio Moreno1 1Renal, Vascular and Diabetes Research Lab, IIS-Fundaciòn Jiménez Dìaz, Autonoma University, 2Department of Physiology, Faculty of Medicine, Complutense University, 3Department of Immunology, Centro Nacional de Microbiologìa, Instituto de Salud Carlos III (ISCIII) JoVE 54599 Immunology and Infection