Nicholas E. Leadbeater Department of Chemistry University of Connecticut Biography Publications Institution JoVE Articles Nicholas E. Leadbeater has not added a biography. If you are Nicholas E. Leadbeater and would like to personalize this page please email our Author Liaison for assistance. Publications Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model The Journal of Organic Chemistry. Aug, 2015 | Pubmed ID: 26167866 Oxidative Cleavage of Allyl Ethers by an Oxoammonium Salt Organic & Biomolecular Chemistry. Apr, 2015 | Pubmed ID: 25748071 Access to Nitriles from Aldehydes Mediated by an Oxoammonium Salt Angewandte Chemie (International Ed. in English). Mar, 2015 | Pubmed ID: 25665019 Methylenation of Perfluoroalkyl Ketones Using a Peterson Olefination Approach The Journal of Organic Chemistry. Feb, 2014 | Pubmed ID: 24410210 Opening an Aladdin's Cave: the Suzuki Coupling in a Room-temperature Ionic Liquid Chemical Communications (Cambridge, England). Feb, 2014 | Pubmed ID: 24383065 Trifluoromethyl Ketones: Properties, Preparation, and Application Chemical Communications (Cambridge, England). Dec, 2013 | Pubmed ID: 24162741 Raman Spectroscopy As a Tool for Monitoring Mesoscale Continuous-flow Organic Synthesis: Equipment Interface and Assessment in Four Medicinally-relevant Reactions Beilstein Journal of Organic Chemistry. 2013 | Pubmed ID: 24062851 Oxidative Esterification of Aldehydes Using a Recyclable Oxoammonium Salt Organic Letters. May, 2013 | Pubmed ID: 23614873 Synthesis of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium Tetrafluoroborate and 4-acetamido-(2,2,6,6-tetramethyl-piperidin-1-yl)oxyl and Their Use in Oxidative Reactions Nature Protocols. Apr, 2013 | Pubmed ID: 23471111 The Central Role of Chemistry in 'quality by Design' Approaches to Drug Development Future Medicinal Chemistry. Sep, 2012 | Pubmed ID: 23043477 Ask the Experts: the Challenges and Benefits of Flow Chemistry to Optimize Drug Development Future Medicinal Chemistry. Sep, 2012 | Pubmed ID: 23043475 Oxidation of α-trifluoromethyl Alcohols Using a Recyclable Oxoammonium Salt The Journal of Organic Chemistry. Sep, 2012 | Pubmed ID: 22931546 A Weinreb Amide Approach to the Synthesis of Trifluoromethylketones Chemical Communications (Cambridge, England). Oct, 2012 | Pubmed ID: 22911019 Access to Dienophilic Ene-triketone Synthons by Oxidation of Diketones with an Oxoammonium Salt Organic Letters. Jan, 2012 | Pubmed ID: 22206582 Continuous-flow, Palladium-catalysed Alkoxycarbonylation Reactions Using a Prototype Reactor in Which It is Possible to Load Gas and Heat Simultaneously Organic & Biomolecular Chemistry. Oct, 2011 | Pubmed ID: 21850299 Titanium-catalyzed Esterification and Transesterification Reactions Facilitated Using Microwave Heating Future Medicinal Chemistry. Feb, 2010 | Pubmed ID: 21426189 Cross Coupling: When is Free Really Free? Nature Chemistry. Dec, 2010 | Pubmed ID: 21107360 In Situ Reaction Monitoring of Microwave-mediated Reactions Using IR Spectroscopy Chemical Communications (Cambridge, England). Sep, 2010 | Pubmed ID: 20717594 Probing "microwave Effects" Using Raman Spectroscopy Organic & Biomolecular Chemistry. Sep, 2009 | Pubmed ID: 19707691 Assessment and Use of Two Silicon Carbide Multi-well Plates for Library Synthesis and Proteolytic Digests Using Microwave Heating Organic & Biomolecular Chemistry. Jun, 2009 | Pubmed ID: 19462057 Palladium-catalyzed Synthesis of Diarylmethanes: Exploitation of Carbanionic Leaving Groups Organic Letters. Jun, 2009 | Pubmed ID: 19456122 Testing the Validity of Microwave-interfaced, in Situ Raman Spectroscopy As a Tool for Kinetic Studies Organic Letters. Jan, 2009 | Pubmed ID: 19072323 Palladium-catalyzed Decarboxylative Coupling of Aromatic Acids with Aryl Halides or Unactivated Arenes Using Microwave Heating Chemical Communications (Cambridge, England). Dec, 2008 | Pubmed ID: 19048139 Use of Raman Spectroscopy As an in Situ Tool to Obtain Kinetic Data for Organic Transformations Chemistry (Weinheim an Der Bergstrasse, Germany). 2008 | Pubmed ID: 18830985 Preparation of Nonsymmetrically Substituted Stilbenes in a One-pot Two-step Heck Strategy Using Ethene As a Reagent The Journal of Organic Chemistry. May, 2008 | Pubmed ID: 18410149 Microwave-promoted Insertion of Group 10 Metals into Free Base Porphyrins and Chlorins: Scope and Limitations Dalton Transactions (Cambridge, England : 2003). Mar, 2008 | Pubmed ID: 18305846 Use of Raman Spectroscopy As a Tool for in Situ Monitoring of Microwave-promoted Reactions Nature Protocols. 2008 | Pubmed ID: 18193016 In Situ Raman Spectroscopy As a Probe for the Effect of Power on Microwave-promoted Suzuki Coupling Reactions Organic & Biomolecular Chemistry. Sep, 2007 | Pubmed ID: 17700844 Microwave Energy: a Versatile Tool for the Biosciences Organic & Biomolecular Chemistry. Apr, 2007 | Pubmed ID: 17406708 Probing the Effects of Microwave Irradiation on Enzyme-catalysed Organic Transformations: the Case of Lipase-catalysed Transesterification Reactions Organic & Biomolecular Chemistry. Apr, 2007 | Pubmed ID: 17377658 Using in Situ Raman Monitoring As a Tool for Rapid Optimisation and Scale-up of Microwave-promoted Organic Synthesis: Esterification As an Example Organic & Biomolecular Chemistry. Mar, 2007 | Pubmed ID: 17315069 Alkoxycarbonylation of Aryl Iodides Using Gaseous Carbon Monoxide and Pre-pressurized Reaction Vessels in Conjunction with Microwave Heating Organic & Biomolecular Chemistry. Jan, 2007 | Pubmed ID: 17164908 Real-time Monitoring of Microwave-promoted Organometallic Ligand-substitution Reactions Using in Situ Raman Spectroscopy Chemical Communications (Cambridge, England). Sep, 2006 | Pubmed ID: 17047782 Real-time Monitoring of Microwave-promoted Suzuki Coupling Reactions Using in Situ Raman Spectroscopy Organic Letters. Sep, 2006 | Pubmed ID: 16986957 Fast, Easy, Clean Chemistry by Using Water As a Solvent and Microwave Heating: the Suzuki Coupling As an Illustration Chemical Communications (Cambridge, England). Jun, 2005 | Pubmed ID: 15957019 Suzuki Coupling of Aryl Chlorides with Phenylboronic Acid in Water, Using Microwave Heating with Simultaneous Cooling Organic Letters. May, 2005 | Pubmed ID: 15901144 Microwave-promoted Heck Coupling Using Ultralow Metal Catalyst Concentrations The Journal of Organic Chemistry. Mar, 2005 | Pubmed ID: 15730302 A Reassessment of the Transition-metal Free Suzuki-type Coupling Methodology The Journal of Organic Chemistry. Jan, 2005 | Pubmed ID: 15624918 Microwave-assisted Mannich-type Three-component Reactions Molecular Diversity. 2003 | Pubmed ID: 14870842 Rapid, Easy Cyanation of Aryl Bromides and Chlorides Using Nickel Salts in Conjunction with Microwave Promotion The Journal of Organic Chemistry. Nov, 2003 | Pubmed ID: 14604393 First Examples of Transition-metal Free Sonogashira-type Couplings Organic Letters. Oct, 2003 | Pubmed ID: 14535743 Rapid Cyanation of Aryl Iodides in Water Using Microwave Promotion Organic & Biomolecular Chemistry. Apr, 2003 | Pubmed ID: 12926385 Transition-metal-free Suzuki-type Coupling Reactions: Scope and Limitations of the Methodology The Journal of Organic Chemistry. Jul, 2003 | Pubmed ID: 12839459 Transition-metal-free Suzuki-type Coupling Reactions Angewandte Chemie (International Ed. in English). Mar, 2003 | Pubmed ID: 12671982 Rapid and Amenable Suzuki Coupling Reaction in Water Using Microwave and Conventional Heating The Journal of Organic Chemistry. Feb, 2003 | Pubmed ID: 12558412 Polymer-supported Metal-phosphine Complexes for Use As Catalysts or Linkers in Medicinally-oriented Organic Synthesis Current Medicinal Chemistry. Dec, 2002 | Pubmed ID: 12470252 Preparation of Polymer-supported Ligands and Metal Complexes for Use in Catalysis Chemical Reviews. Oct, 2002 | Pubmed ID: 12371884 Ligand-free Palladium Catalysis of the Suzuki Reaction in Water Using Microwave Heating Organic Letters. Aug, 2002 | Pubmed ID: 12182602 Polymer-bound 1-aryl-3-alkyltriazenes As Modular Ligands for Catalysis. Part 2: Screening Immobilized Metal Complexes for Catalytic Activity Bioorganic & Medicinal Chemistry Letters. Jul, 2002 | Pubmed ID: 12086832 Polymer-bound 1-aryl-3-alkyltriazenes As Modular Ligands for Catalysis. Part 1: Synthesis and Metal Coordination Bioorganic & Medicinal Chemistry Letters. Jul, 2002 | Pubmed ID: 12086831 Microencapsulated VO(acac)2: Preparation and Use in Allylic Alcohol Epoxidation Organic Letters. May, 2002 | Pubmed ID: 11975618 A Study of the Ionic Liquid Mediated Microwave Heating of Organic Solvents The Journal of Organic Chemistry. May, 2002 | Pubmed ID: 11975584 Monitoramento em tempo real de Reações realizada utilizando processamento de fluxo contínuo: A Preparação de 3-Acetylcoumarin como Exemplo Trevor A. Hamlin1, Nicholas E. Leadbeater1 1Department of Chemistry, University of Connecticut JoVE 52393 Chemistry
Monitoramento em tempo real de Reações realizada utilizando processamento de fluxo contínuo: A Preparação de 3-Acetylcoumarin como Exemplo Trevor A. Hamlin1, Nicholas E. Leadbeater1 1Department of Chemistry, University of Connecticut JoVE 52393 Chemistry