Niels Fertig Nanion Technologies GmbH Biography Publications Institution JoVE Articles Niels Fertig has not added a biography. If you are Niels Fertig and would like to personalize this page please email our Author Liaison for assistance. Publications A Modern Automated Patch-clamp Approach for High Throughput Electrophysiology Recordings in Native Cardiomyocytes Communications Biology. 09, 2022 | Pubmed ID: 36109584 There is No F in APC: Using Physiological Fluoride-free Solutions for High Throughput Automated Patch Clamp Experiments Frontiers in Molecular Neuroscience. 2022 | Pubmed ID: 36072300 SSM-based Electrophysiology, a Label-free Real-time Method Reveals Sugar Binding & Transport Events in SGLT1 Biosensors & Bioelectronics. Feb, 2022 | Pubmed ID: 34768066 The Suitability of High Throughput Automated Patch Clamp for Physiological Applications The Journal of Physiology. 01, 2022 | Pubmed ID: 34555195 Reliable Identification of Cardiac Conduction Abnormalities in Drug Discovery Using Automated Patch Clamp II: Best Practices for Nav1.5 Peak Current in a High Throughput Screening Environment Journal of Pharmacological and Toxicological Methods. Nov-Dec, 2021 | Pubmed ID: 34500078 A Scalable Approach Reveals Functional Responses of IPSC Cardiomyocyte 3D Spheroids SLAS Discovery : Advancing Life Sciences R & D. 03, 2021 | Pubmed ID: 33283596 Electrophysiology on Channel-Forming Proteins in Artificial Lipid Bilayers: Next-Generation Instrumentation for Multiple Recordings in Parallel Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33119847 Integration of Mechanical Conditioning into a High Throughput Contractility Assay for Cardiac Safety Assessment Journal of Pharmacological and Toxicological Methods. Sep, 2020 | Pubmed ID: 32629160 Reliable Identification of Cardiac Liability in Drug Discovery Using Automated Patch Clamp: Benchmarking Best Practices and Calibration Standards for Improved Proarrhythmic Assessment Journal of Pharmacological and Toxicological Methods. Sep, 2020 | Pubmed ID: 32565325 Automated Dynamic Clamp for Simulation of I in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Real Time Using Patchliner Dynamite Current Protocols in Pharmacology. 03, 2020 | Pubmed ID: 31868992 Real-time Monitoring β-lactam/β-lactamase Inhibitor (BL/BLI) Mixture Towards the Bacteria Porin Pathway at Single Molecule Level Analytical and Bioanalytical Chemistry. Mar, 2019 | Pubmed ID: 30824965 A Novel Gain-of-function Mutation of Piezo1 is Functionally Affirmed in Red Blood Cells by High-throughput Patch Clamp Haematologica. 05, 2019 | Pubmed ID: 30237269 An Update on the Advancing High-throughput Screening Techniques for Patch Clamp-based Ion Channel Screens: Implications for Drug Discovery Expert Opinion on Drug Discovery. 03, 2018 | Pubmed ID: 29343120 Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on HiPSC-Derived Cardiomyocytes Toxicological Sciences : an Official Journal of the Society of Toxicology. 11, 2016 | Pubmed ID: 27503387 Safety Pharmacology Studies Using EFP and Impedance Journal of Pharmacological and Toxicological Methods. Sep-Oct, 2016 | Pubmed ID: 27084108 A Biomimetic DNA-based Channel for the Ligand-controlled Transport of Charged Molecular Cargo Across a Biological Membrane Nature Nanotechnology. Feb, 2016 | Pubmed ID: 26751170 Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module Journal of Laboratory Automation. Dec, 2016 | Pubmed ID: 26702021 Novel Screening Techniques for Ion Channel Targeting Drugs Channels (Austin, Tex.). 2015 | Pubmed ID: 26556400 Antibiotic Translocation Through Porins Studied in Planar Lipid Bilayers Using Parallel Platforms The Analyst. Jul, 2015 | Pubmed ID: 25834843 New Easy-to-use Hybrid System for Extracellular Potential and Impedance Recordings Journal of Laboratory Automation. Apr, 2015 | Pubmed ID: 25532527 Bilayer-spanning DNA Nanopores with Voltage-switching Between Open and Closed State ACS Nano. Feb, 2015 | Pubmed ID: 25338165 Temperature-sensitive Gating of HCx26: High-resolution Raman Spectroscopy Sheds Light on Conformational Changes Biomedical Optics Express. Jul, 2014 | Pubmed ID: 25071948 Membrane Assembly of the Functional KcsA Potassium Channel in a Vesicle-based Eukaryotic Cell-free Translation System Biosensors & Bioelectronics. Sep, 2014 | Pubmed ID: 24727603 Minimized Cell Usage for Stem Cell-derived and Primary Cells on an Automated Patch Clamp System Journal of Pharmacological and Toxicological Methods. Jul-Aug, 2013 | Pubmed ID: 23567076 Characterizing Human Ion Channels in Induced Pluripotent Stem Cell-derived Neurons Journal of Biomolecular Screening. Oct, 2012 | Pubmed ID: 22923790 Green Fluorescent Protein Changes the Conductance of Connexin 43 (Cx43) Hemichannels Reconstituted in Planar Lipid Bilayers The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22139870 State-of-the-Art Automated Patch Clamp Devices: Heat Activation, Action Potentials, and High Throughput in Ion Channel Screening Frontiers in Pharmacology. 2011 | Pubmed ID: 22131976 Automated Patch Clamp on MESC-derived Cardiomyocytes for Cardiotoxicity Prediction Journal of Biomolecular Screening. Sep, 2011 | Pubmed ID: 21775699 The M34A Mutant of Connexin26 Reveals Active Conductance States in Pore-suspending Membranes Journal of Structural Biology. Oct, 2009 | Pubmed ID: 19236918 Port-a-patch and Patchliner: High Fidelity Electrophysiology for Secondary Screening and Safety Pharmacology Combinatorial Chemistry & High Throughput Screening. Jan, 2009 | Pubmed ID: 19149489 Planar Patch Clamp: Advances in Electrophysiology Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18998092 Rapid Screening of Membrane Protein Activity: Electrophysiological Analysis of OmpF Reconstituted in Proteoliposomes Lab on a Chip. Apr, 2008 | Pubmed ID: 18369514 Automated Ion Channel Screening: Patch Clamping Made Easy Expert Opinion on Therapeutic Targets. Apr, 2007 | Pubmed ID: 17373884 Microchip Technology for Automated and Parallel Patch-clamp Recording Small (Weinheim an Der Bergstrasse, Germany). Jul, 2006 | Pubmed ID: 17193131 Microstructured Apertures in Planar Glass Substrates for Ion Channel Research Receptors & Channels. 2003 | Pubmed ID: 12825296 מערכת ניתוח תאים היברידית להערכת שינויים מבניים והתכווצות של קרדיומיוציטים שמקורם ב- iPSC אנושי להערכת סיכון לבבי פרה-קליני Bettina Lickiss1, Matthias Gossmann1, Peter Linder1, Ulrich Thomas2, Elena Dragicevic2, Marta Lemme2, Michael George2, Niels Fertig2, Sonja Stölzle-Feix2 1innoVitro GmbH, 2Nanion Technologies GmbH JoVE 64283 Bioengineering
מערכת ניתוח תאים היברידית להערכת שינויים מבניים והתכווצות של קרדיומיוציטים שמקורם ב- iPSC אנושי להערכת סיכון לבבי פרה-קליני Bettina Lickiss1, Matthias Gossmann1, Peter Linder1, Ulrich Thomas2, Elena Dragicevic2, Marta Lemme2, Michael George2, Niels Fertig2, Sonja Stölzle-Feix2 1innoVitro GmbH, 2Nanion Technologies GmbH JoVE 64283 Bioengineering