Ole Munk Department of Nuclear Medicine & PET-Center Aarhus University Hospital Biography Publications Institution JoVE Articles Ole Munk has not added a biography. If you are Ole Munk and would like to personalize this page please email our Author Liaison for assistance. Publications Multiparametric Dynamic Whole-body PSMA PET/CT Using [Ga]Ga-PSMA-11 and [F]PSMA-1007 EJNMMI Research. Apr, 2023 | Pubmed ID: 37060394 Distribution of Cholinergic Nerve Terminals in the Aged Human Brain Measured with [F]FEOBV PET and Its Correlation with Histological Data NeuroImage. Apr, 2023 | Pubmed ID: 36720436 Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [18F]FEOBV PET Case-Control Study Journal of Parkinson's Disease. 2022 | Pubmed ID: 36336941 [F]FEOBV Positron Emission Tomography May Not Be a Suitable Method to Measure Parasympathetic Denervation in Patients with Parkinson's Disease Parkinsonism & Related Disorders. Nov, 2022 | Pubmed ID: 36198248 N-(4-[F]fluorobenzyl)cholylglycine, a Potential Tracer for Positron Emission Tomography of Enterohepatic Circulation and Drug-induced Inhibition of Ileal Bile Acid Transport. A Proof-of-concept PET/CT Study in Pigs Nuclear Medicine and Biology. 2022 | Pubmed ID: 36095922 Clinical Validation of a Population-based Input Function for 20-min Dynamic Whole-body F-FDG Multiparametric PET Imaging EJNMMI Physics. Sep, 2022 | Pubmed ID: 36076097 In Vivo Vesicular Acetylcholine Transporter Density in Human Peripheral Organs: an [F]FEOBV PET/CT Study EJNMMI Research. Apr, 2022 | Pubmed ID: 35362761 Clinical Feasibility and Impact of Data-driven Respiratory Motion Compensation Studied in 200 Whole-body F-FDG PET/CT Scans EJNMMI Research. Mar, 2022 | Pubmed ID: 35347465 Normal Values for F-FDG Uptake in Organs and Tissues Measured by Dynamic Whole Body Multiparametric FDG PET in 126 Patients EJNMMI Research. Mar, 2022 | Pubmed ID: 35254514 The Pathophysiology of Wilson's Disease Visualized: A human Cu PET Study Hepatology (Baltimore, Md.). Jun, 2022 | Pubmed ID: 34773664 Validation and Optimisation of an Automatic Blood Sampler for Preclinical Positron Emission Tomography Research in Domestic Pigs Laboratory Animals. Jun, 2022 | Pubmed ID: 34596450 Reply To: "Hepatic Bile Acid Transport Increases in the Postprandial State: A Functional C-CSar PET/CT Study in Healthy Humans" JHEP Reports : Innovation in Hepatology. Dec, 2021 | Pubmed ID: 34746727 Hepatic Bile Acid Transport Increases in the Postprandial State: A functional C-CSar PET/CT Study in Healthy Humans JHEP Reports : Innovation in Hepatology. Jun, 2021 | Pubmed ID: 34095797 Correction To: Clinical Feasibility and Impact of Fully Automated Multiparametric PET Imaging Using Direct Patlak Reconstruction: Evaluation of 103 Dynamic Whole-body 18F-FDG PET/CT Scans European Journal of Nuclear Medicine and Molecular Imaging. Mar, 2021 | Pubmed ID: 33582877 NMDA Receptor Ion Channel Activation Detected in Vivo with [F]GE-179 PET After Electrical Stimulation of Rat Hippocampus Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2021 | Pubmed ID: 32960687 Clinical Feasibility and Impact of Fully Automated Multiparametric PET Imaging Using Direct Patlak Reconstruction: Evaluation of 103 Dynamic Whole-body F-FDG PET/CT Scans European Journal of Nuclear Medicine and Molecular Imaging. Mar, 2021 | Pubmed ID: 32894338 Obeticholic Acid Improves Hepatic Bile Acid Excretion in Patients with Primary Biliary Cholangitis Journal of Hepatology. Jan, 2021 | Pubmed ID: 32717289 Successful Prediction of Positron Emission Tomography-Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics-Informed Relative Expression Factor Approach Drug Metabolism and Disposition: the Biological Fate of Chemicals. Nov, 2020 | Pubmed ID: 32843330 Brain-first Versus Body-first Parkinson's Disease: a Multimodal imaging Case-control Study Brain : a Journal of Neurology. Oct, 2020 | Pubmed ID: 32830221 Intravenous and Oral Copper Kinetics, Biodistribution and Dosimetry in Healthy Humans Studied by [Cu]copper PET/CT EJNMMI Radiopharmacy and Chemistry. Jun, 2020 | Pubmed ID: 32556736 Activation of NMDA Receptor Ion Channels by Deep Brain Stimulation in the Pig Visualised with [F]GE-179 PET Brain Stimulation. 2020 | Pubmed ID: 32388196 Metformin is Distributed to Tumor Tissue in Breast Cancer Patients in Vivo: A C-metformin PET/CT Study Breast Cancer Research and Treatment. May, 2020 | Pubmed ID: 32240455 Human Biodistribution, Dosimetry, Radiosynthesis and Quality Control of the Bile Acid PET Tracer [N-methyl-C]cholylsarcosine Nuclear Medicine and Biology. 2019 | Pubmed ID: 31330413 Hepatic Exposure of Metformin in Patients with Non-alcoholic Fatty Liver Disease British Journal of Clinical Pharmacology. Aug, 2019 | Pubmed ID: 30973968 Prognostic Modeling for Patients with Colorectal Liver Metastases Incorporating FDG PET Radiomic Features European Journal of Radiology. Apr, 2019 | Pubmed ID: 30927933 Quantitative PET of Liver Functions American Journal of Nuclear Medicine and Molecular Imaging. 2018 | Pubmed ID: 29755841 Monitoring Variables Affecting Positron Emission Tomography Measurements of Cerebral Blood Flow in Anaesthetized Pigs Acta Veterinaria Scandinavica. Mar, 2018 | Pubmed ID: 29530059 Metformin Does Not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans: A 3-month Placebo-controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls Diabetes, Obesity & Metabolism. Jun, 2018 | Pubmed ID: 29405635 Cerebral Blood Flow Measured by Positron Emission Tomography During Normothermic Cardiopulmonary Bypass: an Experimental Porcine Study Perfusion. Jul, 2018 | Pubmed ID: 29380669 Whole-Body Biodistribution, Dosimetry, and Metabolite Correction of [C]Palmitate: A PET Tracer for Imaging of Fatty Acid Metabolism Molecular Imaging. 2017 | Pubmed ID: 29073808 A Microvascular Compartment Model Validated Using C-methylglucose Liver PET in Pigs Physics in Medicine and Biology. Dec, 2017 | Pubmed ID: 29045236 Hepatic Metabolism of C-methionine and Secretion of C-protein Measured by PET in Pigs American Journal of Nuclear Medicine and Molecular Imaging. 2017 | Pubmed ID: 28913155 Metabolic Liver Function in Humans Measured by 2-F-fluoro-2-deoxy-D-galactose PET/CT-reproducibility and Clinical Potential EJNMMI Research. Aug, 2017 | Pubmed ID: 28853060 Hypoxia Positron Emission Tomography Imaging: Combining Information on Perfusion and Tracer Retention to Improve Hypoxia Specificity Acta Oncologica (Stockholm, Sweden). Nov, 2017 | Pubmed ID: 28840765 The Potential of Hyperpolarized C Magnetic Resonance Spectroscopy to Monitor the Effect of Combretastatin Based Vascular Disrupting Agents Acta Oncologica (Stockholm, Sweden). Nov, 2017 | Pubmed ID: 28840759 Muscle Tissue Saturation Compared With Muscle Tissue Perfusion During Low Blood Flows: An Experimental Study Journal of Cardiothoracic and Vascular Anesthesia. Dec, 2017 | Pubmed ID: 28693932 Magnetic Resonance Imaging and Computed Tomography As Tools for the Investigation of Sperm Whale (Physeter Macrocephalus) Teeth and Eye Acta Veterinaria Scandinavica. Jun, 2017 | Pubmed ID: 28606113 Hepatobiliary Transport Kinetics of the Conjugated Bile Acid Tracer C-CSar Quantified in Healthy Humans and Patients by Positron Emission Tomography Journal of Hepatology. Aug, 2017 | Pubmed ID: 28249726 FDG-PET Reproducibility in Tumor-bearing Mice: Comparing a Traditional SUV Approach with a Tumor-to-brain Tissue Ratio Approach Acta Oncologica (Stockholm, Sweden). May, 2017 | Pubmed ID: 28094665 Point-spread Function Reconstructed PET Images of Sub-centimeter Lesions Are Not Quantitative EJNMMI Physics. Dec, 2017 | Pubmed ID: 28091957 In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Dec, 2016 | Pubmed ID: 27469359 2-[(18)F]fluoro-2-deoxy-D-galactose PET/CT of Hepatocellular Carcinoma is Not Improved by Co-administration of Galactose Nuclear Medicine and Biology. Sep, 2016 | Pubmed ID: 27434609 Renal PET-imaging with (11)C-metformin in a Transgenic Mouse Model for Chronic Kidney Disease EJNMMI Research. Dec, 2016 | Pubmed ID: 27339044 [11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency Diabetes. Jun, 2016 | Pubmed ID: 26993065 Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by 11C-Cholylsarcosine PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2016 | Pubmed ID: 26966160 A PET Tracer for Renal Organic Cation Transporters, ¹¹C-Metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2016 | Pubmed ID: 26769859 Radiosynthesis of N-¹¹C-Methyl-Taurine-Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2016 | Pubmed ID: 26697965 Metabolic Liver Function Measured in Vivo by Dynamic (18)F-FDGal PET/CT Without Arterial Blood Sampling EJNMMI Research. 2015 | Pubmed ID: 26034654 Imaging Acetylcholinesterase Density in Peripheral Organs in Parkinson's Disease with 11C-donepezil PET Brain : a Journal of Neurology. Mar, 2015 | Pubmed ID: 25539902 In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-donepezil: Dosimetry, Biodistribution, and Kinetic Analyses Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2014 | Pubmed ID: 25324520 Hepatic Encephalopathy is Associated with Decreased Cerebral Oxygen Metabolism and Blood Flow, Not Increased Ammonia Uptake Hepatology (Baltimore, Md.). Jan, 2013 | Pubmed ID: 22886493 Hepatic Blood Perfusion Estimated by Dynamic Contrast-enhanced Computed Tomography in Pigs: Limitations of the Slope Method Investigative Radiology. Oct, 2012 | Pubmed ID: 22836307 [N-methyl-11C]cholylsarcosine, a Novel Bile Acid Tracer for PET/CT of Hepatic Excretory Function: Radiosynthesis and Proof-of-concept Studies in Pigs Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2012 | Pubmed ID: 22454486 Model-independent Plot of Dynamic PET Data Facilitates Data Interpretation and Model Selection Journal of Theoretical Biology. Feb, 2012 | Pubmed ID: 22094364 PET Kinetics of Radiolabeled Antidepressant, [N-methyl-11C]mirtazapine, in the Human Brain EJNMMI Research. Dec, 2011 | Pubmed ID: 22214419 Analogue Tracers and Lumped Constant in Capillary Beds Journal of Theoretical Biology. Sep, 2011 | Pubmed ID: 21756919 Hepatic Blood Perfusion Measured by 3-minute Dynamic 18F-FDG PET in Pigs Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2011 | Pubmed ID: 21680685 Branched-chain Amino Acids Increase Arterial Blood Ammonia in Spite of Enhanced Intrinsic Muscle Ammonia Metabolism in Patients with Cirrhosis and Healthy Subjects American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2011 | Pubmed ID: 21636533 Tracer Input for Kinetic Modelling of Liver Physiology Determined Without Sampling Portal Venous Blood in Pigs European Journal of Nuclear Medicine and Molecular Imaging. Feb, 2011 | Pubmed ID: 20882283 Identifying Hypoxia in Human Tumors: A Correlation Study Between 18F-FMISO PET and the Eppendorf Oxygen-sensitive Electrode Acta Oncologica (Stockholm, Sweden). Oct, 2010 | Pubmed ID: 20831480 Assessing Hypoxia in Animal Tumor Models Based on Pharmocokinetic Analysis of Dynamic FAZA PET Acta Oncologica (Stockholm, Sweden). Oct, 2010 | Pubmed ID: 20831479 Human (13)N-ammonia PET Studies: the Importance of Measuring (13)N-ammonia Metabolites in Blood Metabolic Brain Disease. Mar, 2010 | Pubmed ID: 20217201 Hepatic Ethanol Elimination Kinetics in Patients with Cirrhosis Scandinavian Journal of Gastroenterology. 2009 | Pubmed ID: 19404864 Backflux of Ammonia from Brain to Blood in Human Subjects with and Without Hepatic Encephalopathy Metabolic Brain Disease. Mar, 2009 | Pubmed ID: 19067140 Benefits and Risks of Transforming Data from Dynamic Positron Emission Tomography, with an Application to Hepatic Encephalopathy Journal of Theoretical Biology. Feb, 2009 | Pubmed ID: 19038272 ISSLS Prize Winner: Positron Emission Tomography and Magnetic Resonance Imaging for Monitoring Interbody Fusion with Equine Bone Protein Extract, Recombinant Human Bone Morphogenetic Protein-2, and Autograft Spine. Dec, 2008 | Pubmed ID: 19002076 A Method to Estimate Dispersion in Sampling Catheters and to Calculate Dispersion-free Blood Time-activity Curves Medical Physics. Aug, 2008 | Pubmed ID: 18777907 Hepatic Uptake and Metabolism of Galactose Can Be Quantified in Vivo by 2-[18F]fluoro-2-deoxygalactose Positron Emission Tomography American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2008 | Pubmed ID: 18483186 Peripheral Benzodiazepine Receptors in the Brain of Cirrhosis Patients with Manifest Hepatic Encephalopathy European Journal of Nuclear Medicine and Molecular Imaging. Jul, 2006 | Pubmed ID: 16550382 Individual Radiation Response of Parotid Glands Investigated by Dynamic 11C-methionine PET Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Mar, 2006 | Pubmed ID: 16545879 Brain Metabolism of 13N-ammonia During Acute Hepatic Encephalopathy in Cirrhosis Measured by Positron Emission Tomography Hepatology (Baltimore, Md.). Jan, 2006 | Pubmed ID: 16374868 Effect of Intratumoral Heterogeneity in Oxygenation Status on FMISO PET, Autoradiography, and Electrode Po2 Measurements in Murine Tumors International Journal of Radiation Oncology, Biology, Physics. Jul, 2005 | Pubmed ID: 15936570 Hepatic Microcirculation Assessed by Positron Emission Tomography of First-pass Ammonia Metabolism in Porcine Liver Liver International : Official Journal of the International Association for the Study of the Liver. Feb, 2005 | Pubmed ID: 15698415 11C-methionine PET, a Novel Method for Measuring Regional Salivary Gland Function After Radiotherapy of Head and Neck Cancer Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Dec, 2004 | Pubmed ID: 15588873 Determination of Regional Flow by Use of Intravascular PET Tracers: Microvascular Theory and Experimental Validation for Pig Livers Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2003 | Pubmed ID: 14602871 Capillaries Within Compartments: Microvascular Interpretation of Dynamic Positron Emission Tomography Data Journal of Theoretical Biology. Nov, 2003 | Pubmed ID: 14559065 Impulse-response Function of Splanchnic Circulation with Model-independent Constraints: Theory and Experimental Validation American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2003 | Pubmed ID: 12686507 Metabolic Fate of 18F-FDG in Mice Bearing Either SCCVII Squamous Cell Carcinoma or C3H Mammary Carcinoma Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2002 | Pubmed ID: 12097467 Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders Ditte Emilie Munk1, Frederik Teicher Kirk1, Mikkel Vendelbo2, Karina Vase2, Ole Munk2, Peter Ott1, Thomas Damgaard Sandahl1 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, 2Department of Nuclear Medicine & PET-Center, Aarhus University Hospital JoVE 65109 Medicine
Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders Ditte Emilie Munk1, Frederik Teicher Kirk1, Mikkel Vendelbo2, Karina Vase2, Ole Munk2, Peter Ott1, Thomas Damgaard Sandahl1 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, 2Department of Nuclear Medicine & PET-Center, Aarhus University Hospital JoVE 65109 Medicine