Orlando Laitano Biography Publications JoVE Articles Orlando Laitano has not added a biography. If you are Orlando Laitano and would like to personalize this page please email our Author Liaison for assistance. Publications There's a Seat at the Table for All! Converging Disciplines Toward Understanding and Mitigating Heat-related Mortality Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2024 | Pubmed ID: 38836541 Consideration of Sex As a Biological Variable in the Context of Thermal Physiology and Biometeorological Research Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2024 | Pubmed ID: 38836537 Exertional Heat Stroke Causes Long-term Skeletal Muscle Epigenetic Reprogramming, Altered Gene Expression, and Impaired Satellite Cell Function in Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2024 | Pubmed ID: 38047316 Deletion of the Aryl Hydrocarbon Receptor in Endothelial Cells Improves Ischemic Angiogenesis in Chronic Kidney Disease American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2024 | Pubmed ID: 37921663 Activation of the Aryl Hydrocarbon Receptor in Endothelial Cells Impairs Ischemic Angiogenesis in Chronic Kidney Disease BioRxiv : the Preprint Server for Biology. Jul, 2023 | Pubmed ID: 37546909 Blocking Muscle Wasting Via Deletion of the Muscle-specific E3 Ligase MuRF1 Impedes Pancreatic Tumor Growth Communications Biology. May, 2023 | Pubmed ID: 37179425 Ovariectomy Aggravates the Pathophysiological Response to Exertional Heat Stroke in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2023 | Pubmed ID: 37022961 Blocking Muscle Wasting Via Deletion of the Muscle-specific E3 Ubiquitin Ligase MuRF1 Impedes Pancreatic Tumor Growth Research Square. Feb, 2023 | Pubmed ID: 36798266 Exertional Heat Stroke: Pathophysiology and Risk Factors BMJ Medicine. 2022 | Pubmed ID: 36936589 Neuromotor Deficits and Altered Physiological Responses to Repeated Exertional Heat Stroke Exposures in Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2022 | Pubmed ID: 36279505 The Impact of Castration on Physiological Responses to Exertional Heat Stroke in Mice PloS One. 2022 | Pubmed ID: 36227921 Heat Stroke: Physiological Challenges and Breakthroughs Experimental Physiology. Oct, 2022 | Pubmed ID: 36178301 The Effect of Prolonged Interval and Continuous Exercise in the Heat on Circulatory Markers of Intestinal Barrier Integrity European Journal of Applied Physiology. Dec, 2022 | Pubmed ID: 36114840 The Effect of Interval and Continuous Work on Markers of Acute Kidney Injury in a Hot Environment European Journal of Applied Physiology. Nov, 2022 | Pubmed ID: 35999474 Human Temperature Regulation Under Heat Stress in Health, Disease, and Injury Physiological Reviews. Oct, 2022 | Pubmed ID: 35679471 Sex Differences Associate with Late Microbiome Alterations After Murine Surgical Sepsis The Journal of Trauma and Acute Care Surgery. Aug, 2022 | Pubmed ID: 35324554 Lipopolysaccharide-Induced Cytokine Secretion from In Vitro Mouse Slow and Fast Limb Muscle Shock (Augusta, Ga.). Apr, 2022 | Pubmed ID: 34798635 Sepsis-Induced Myopathy and Gut Microbiome Dysbiosis: Mechanistic Links and Therapeutic Targets Shock (Augusta, Ga.). Jan, 2022 | Pubmed ID: 34726875 The Impact of Hindlimb Disuse on Sepsis-induced Myopathy in Mice Physiological Reports. 07, 2021 | Pubmed ID: 34309237 Pathophysiology and Treatment Strategies of Acute Myopathy and Muscle Wasting After Sepsis Journal of Clinical Medicine. Apr, 2021 | Pubmed ID: 33926035 Skeletal Muscle Fibers Play a Functional Role in Host Defense During Sepsis in Mice Scientific Reports. Apr, 2021 | Pubmed ID: 33795743 Exertional Heat Stroke Leads to Concurrent Long-term Epigenetic Memory, Immunosuppression and Altered Heat Shock Response in Female Mice The Journal of Physiology. 01, 2021 | Pubmed ID: 33037634 Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice Shock (Augusta, Ga.). Apr, 2021 | Pubmed ID: 32826817 Skeletal Muscle Interleukin-6 Contributes to the Innate Immune Response in Septic Mice Shock (Augusta, Ga.). May, 2021 | Pubmed ID: 32826815 Acute Phase Response to Exertional Heat Stroke in Mice Experimental Physiology. Jan, 2021 | Pubmed ID: 32281170 Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence Vs. Conjecture Sports Medicine (Auckland, N.Z.). Sep, 2020 | Pubmed ID: 32632746 Effects of Ibuprofen During Exertional Heat Stroke in Mice Medicine and Science in Sports and Exercise. 09, 2020 | Pubmed ID: 32175974 Delayed Metabolic Dysfunction in Myocardium Following Exertional Heat Stroke in Mice The Journal of Physiology. 03, 2020 | Pubmed ID: 32026469 Controversies in Exertional Heat Stroke Diagnosis, Prevention, and Treatment Journal of Applied Physiology (Bethesda, Md. : 1985). 11, 2019 | Pubmed ID: 31545156 Osmolality Selectively Offsets the Impact of Hyperthermia on Mouse Skeletal Muscle Frontiers in Physiology. 2018 | Pubmed ID: 30429796 Sex-dependent Responses to Exertional Heat Stroke in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). 09, 2018 | Pubmed ID: 29901435 Xiphoid Surface Temperature Predicts Mortality in a Murine Model of Septic Shock Shock (Augusta, Ga.). 08, 2018 | Pubmed ID: 28957876 Epinephrine Stimulates CXCL1 IL-1, IL-6 Secretion in Isolated Mouse Limb Muscle Physiological Reports. Dec, 2017 | Pubmed ID: 29192066 Regulation of NADPH Oxidases in Skeletal Muscle Free Radical Biology & Medicine. 09, 2016 | Pubmed ID: 27184955 The Impact of Hyperthermia on Receptor-Mediated Interleukin-6 Regulation in Mouse Skeletal Muscle PloS One. 2016 | Pubmed ID: 26872389 Pharmacological Targeting of Mitochondrial Reactive Oxygen Species Counteracts Diaphragm Weakness in Chronic Heart Failure Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2016 | Pubmed ID: 26846552 Hyperthermia, Dehydration, and Osmotic Stress: Unconventional Sources of Exercise-induced Reactive Oxygen Species American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jan, 2016 | Pubmed ID: 26561649 A Preclinical Model of Sepsis-Induced Myopathy with Disuse in Mice JoVE 66685 Medicine 小鼠劳力性中暑的临床前模型 Michelle A. King1, Jamal M. Alzahrani1, Thomas L. Clanton1, Orlando Laitano1,2 1Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, 2Department of Nutrition and Integrative Physiology, College of Health and Human Sciences, Florida State University JoVE 62738 Medicine
小鼠劳力性中暑的临床前模型 Michelle A. King1, Jamal M. Alzahrani1, Thomas L. Clanton1, Orlando Laitano1,2 1Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, 2Department of Nutrition and Integrative Physiology, College of Health and Human Sciences, Florida State University JoVE 62738 Medicine