Patrick Pauwels Molecular Pathology, Pathology Department Antwerp University Hospital (UZA) Biography Publications Institution JoVE Articles Patrick Pauwels has not added a biography. If you are Patrick Pauwels and would like to personalize this page please email our Author Liaison for assistance. Publications Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response Cancer Biotherapy & Radiopharmaceuticals. Apr, 2016 | Pubmed ID: 27093343 Long-term Acquired Everolimus Resistance in Pancreatic Neuroendocrine Tumours Can Be Overcome with Novel PI3K-AKT-mTOR Inhibitors British Journal of Cancer. Mar, 2016 | Pubmed ID: 26978006 APR-246 (PRIMA-1(MET)) Strongly Synergizes with AZD2281 (olaparib) Induced PARP Inhibition to Induce Apoptosis in Non-small Cell Lung Cancer Cell Lines Cancer Letters. Jun, 2016 | Pubmed ID: 26975633 Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues The Journal of Molecular Diagnostics : JMD. May, 2016 | Pubmed ID: 26921540 Exosomes Isolation and Characterization in Serum is Feasible in Non-small Cell Lung Cancer Patients: Critical Analysis of Evidence and Potential Role in Clinical Practice Oncotarget. Feb, 2016 | Pubmed ID: 26919248 Baseline [(18)F]FMISO μPET As a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jan, 2016 | Pubmed ID: 26728163 TP53 and MDM2 Genetic Alterations in Non-small Cell Lung Cancer: Evaluating Their Prognostic and Predictive Value Critical Reviews in Oncology/hematology. Mar, 2016 | Pubmed ID: 26689115 Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect Journal of Immunology Research. 2015 | Pubmed ID: 26605342 Targeting Immune Checkpoints: New Opportunity for Mesothelioma Treatment? Cancer Treatment Reviews. Dec, 2015 | Pubmed ID: 26433514 Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2 Drugs. Oct, 2015 | Pubmed ID: 26347132 Proteomics in Cancer Research: Are We Ready for Clinical Practice? Critical Reviews in Oncology/hematology. Dec, 2015 | Pubmed ID: 26277237 CD44 Enhances Tumor Aggressiveness by Promoting Tumor Cell Plasticity Oncotarget. Aug, 2015 | Pubmed ID: 26189059 The MDM2-inhibitor Nutlin-3 Synergizes with Cisplatin to Induce P53 Dependent Tumor Cell Apoptosis in Non-small Cell Lung Cancer Oncotarget. Sep, 2015 | Pubmed ID: 26125230 Unlocking the Potential of CD70 As a Novel Immunotherapeutic Target for Non-small Cell Lung Cancer Oncotarget. May, 2015 | Pubmed ID: 25951351 What Can Platinum Offer Yet in the Treatment of PS2 NSCLC Patients? A Systematic Review and Meta-analysis Critical Reviews in Oncology/hematology. Sep, 2015 | Pubmed ID: 25922216 Onartuzumab in Lung Cancer: the Fall of Icarus? Expert Review of Anticancer Therapy. May, 2015 | Pubmed ID: 25818471 CMET in NSCLC: Can We Cut off the Head of the Hydra? From the Pathway to the Resistance Cancers. 2015 | Pubmed ID: 25815459 Whole-exome Characterization of Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1 Journal of Molecular Endocrinology. Apr, 2015 | Pubmed ID: 25612765 Automation of ALK Gene Rearrangement Testing with Fluorescence in Situ Hybridization (FISH): a Feasibility Study Experimental and Molecular Pathology. Feb, 2015 | Pubmed ID: 25576649 Improvement in Lung Cancer Outcomes with Targeted Therapies: an Update for Family Physicians Journal of the American Board of Family Medicine : JABFM. Jan-Feb, 2015 | Pubmed ID: 25567833 Circulating Tumour Cells and Lung Microvascular Tumour Cell Retention in Patients with Metastatic Breast and Cervical Cancer Cancer Letters. Jan, 2015 | Pubmed ID: 25449778 ALK and Crizotinib: After the Honeymoon…what Else? Resistance Mechanisms and New Therapies to Overcome It Translational Lung Cancer Research. Aug, 2014 | Pubmed ID: 25806308 Expression Profiling of Migrated and Invaded Breast Cancer Cells Predicts Early Metastatic Relapse and Reveals Krüppel-like Factor 9 As a Potential Suppressor of Invasive Growth in Breast Cancer Oncoscience. 2014 | Pubmed ID: 25593984 The Role of CMet in Non-small Cell Lung Cancer Resistant to EGFR-inhibitors: Did We Really Find the Target? Current Drug Targets. 2014 | Pubmed ID: 25511614 Liquid Biopsies in Lung Cancer: the New Ambrosia of Researchers Biochimica Et Biophysica Acta. Dec, 2014 | Pubmed ID: 25444714 Multicenter Immunohistochemical ALK-testing of Non-small-cell Lung Cancer Shows High Concordance After Harmonization of Techniques and Interpretation Criteria Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Nov, 2014 | Pubmed ID: 25436802 The Relevance of External Quality Assessment for Molecular Testing for ALK Positive Non-small Cell Lung Cancer: Results from Two Pilot Rounds Show Room for Optimization PloS One. 2014 | Pubmed ID: 25386659 Overcoming Cetuximab Resistance in HNSCC: the Role of AURKB and DUSP Proteins Cancer Letters. Nov, 2014 | Pubmed ID: 25192874 Immunotherapy: is a Minor God Yet in the Pantheon of Treatments for Lung Cancer? Expert Review of Anticancer Therapy. Oct, 2014 | Pubmed ID: 25148289 The Radiosensitising Effect of Gemcitabine and Its Main Metabolite DFdU Under Low Oxygen Conditions is in Vitro Not Dependent on Functional HIF-1 Protein BMC Cancer. 2014 | Pubmed ID: 25128202 Looking for a New Panacea in ALK-rearranged NSCLC: May Be Ceritinib? Expert Opinion on Therapeutic Targets. Sep, 2014 | Pubmed ID: 24998601 Novel Therapeutic Strategies for Patients with NSCLC That Do Not Respond to Treatment with EGFR Inhibitors Cancer Treatment Reviews. Sep, 2014 | Pubmed ID: 24953979 Mutation Analysis of Genes in the EGFR Pathway in Head and Neck Cancer Patients: Implications for Anti-EGFR Treatment Response BMC Research Notes. 2014 | Pubmed ID: 24899223 Impact of MicroRNAs in Resistance to Chemotherapy and Novel Targeted Agents in Non-small Cell Lung Cancer Current Pharmaceutical Biotechnology. 2014 | Pubmed ID: 24846062 Detection of ALK Expression in Non-small-cell Lung Cancer with ALK Gene Rearrangements--comparison of Multiple Immunohistochemical Methods Histopathology. Oct, 2014 | Pubmed ID: 24621075 Krüppel-like Factors in Cancer Progression: Three Fingers on the Steering Wheel Oncotarget. Jan, 2014 | Pubmed ID: 24429391 Are Erlotinib and Gefitinib Interchangeable, Opposite or Complementary for Non-small Cell Lung Cancer Treatment? Biological, Pharmacological and Clinical Aspects Critical Reviews in Oncology/hematology. Feb, 2014 | Pubmed ID: 24041630 Sarcomatous Degeneration in Fibrous Dysplasia of the Rib Cage The Annals of Thoracic Surgery. Oct, 2013 | Pubmed ID: 24088499 Smooth Muscle Cell Transplantation Improves Bladder Contractile Function in Streptozocin-induced Diabetic Rats Cytotherapy. Jul, 2013 | Pubmed ID: 23731765 Expression Analysis on Archival Material Revisited: Isolation and Quantification of RNA Extracted from FFPE Samples Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Mar, 2013 | Pubmed ID: 23370428 Differential Secretome Analysis of Cancer-associated Fibroblasts and Bone Marrow-derived Precursors to Identify Microenvironmental Regulators of Colon Cancer Progression Proteomics. Jan, 2013 | Pubmed ID: 23175172 Identification of CUX1 As the Recurrent Chromosomal Band 7q22 Target Gene in Human Uterine Leiomyoma Genes, Chromosomes & Cancer. Jan, 2013 | Pubmed ID: 22965931 Quantitative and Phenotypic Analysis of Mesenchymal Stromal Cell Graft Survival and Recognition by Microglia and Astrocytes in Mouse Brain Immunobiology. May, 2013 | Pubmed ID: 22944251 Bone Marrow-derived Mesenchymal Stem Cells Promote Colorectal Cancer Progression Through Paracrine Neuregulin 1/HER3 Signalling Gut. Apr, 2013 | Pubmed ID: 22535374 Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-time Technology and Classic Endpoint Assays PloS One. 2012 | Pubmed ID: 23094027 The Interaction Between ER and NFκB in Resistance to Endocrine Therapy Breast Cancer Research : BCR. 2012 | Pubmed ID: 22963717 EML4-ALK Testing in Non-small Cell Carcinomas of the Lung: a Review with Recommendations Virchows Archiv : an International Journal of Pathology. Sep, 2012 | Pubmed ID: 22825000 An Immunohistochemical Analysis of Rab27B Distribution in Fetal and Adult Tissue The International Journal of Developmental Biology. 2012 | Pubmed ID: 22811270 Cell Type-associated Differences in Migration, Survival, and Immunogenicity Following Grafting in CNS Tissue Cell Transplantation. Apr, 2012 | Pubmed ID: 22472278 Single-photon Emission Computed Tomographic Imaging of the Early Time Course of Therapy-induced Cell Death Using Technetium 99m Tricarbonyl His-annexin A5 in a Colorectal Cancer Xenograft Model Molecular Imaging. Apr, 2012 | Pubmed ID: 22469241 Incidence and Survival Trends of Uncommon Corpus Uteri Malignancies in the Netherlands, 1989-2008 International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. May, 2012 | Pubmed ID: 22398706 Isolated Lung Perfusion with Gemcitabine Combined with Radiotherapy: No Additional Lung Toxicity in an Experimental Model European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Oct, 2012 | Pubmed ID: 22345281 Current Challenges for the Advancement of Neural Stem Cell Biology and Transplantation Research Stem Cell Reviews. Mar, 2012 | Pubmed ID: 21537994 Tumor Cells and Tumor-associated Macrophages: Secreted Proteins As Potential Targets for Therapy Clinical & Developmental Immunology. 2011 | Pubmed ID: 22162712 Expression Analysis on Archival Material: Comparison of 5 Commercially Available RNA Isolation Kits for FFPE Material Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Dec, 2011 | Pubmed ID: 22089347 (99)mTc-(CO)(3) His-annexin A5 Micro-SPECT Demonstrates Increased Cell Death by Irinotecan During the Vascular Normalization Window Caused by Bevacizumab Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2011 | Pubmed ID: 22045708 Expression and Prognostic Value of Glucose Transporters and Hexokinases in Tonsil and Mobile Tongue Squamous Cell Carcinoma Histology and Histopathology. Sep, 2011 | Pubmed ID: 21751148 Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. Dec, 2011 | Pubmed ID: 21618031 EGFR in Melanoma: Clinical Significance and Potential Therapeutic Target Journal of Cutaneous Pathology. Jun, 2011 | Pubmed ID: 21352258 Labeling of Luciferase/eGFP-expressing Bone Marrow-derived Stromal Cells with Fluorescent Micron-sized Iron Oxide Particles Improves Quantitative and Qualitative Multimodal Imaging of Cellular Grafts in Vivo Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Dec, 2011 | Pubmed ID: 21246293 Relationship Between Pathological Features, HER2 Protein Expression and HER2 and CEP17 Copy Number in Breast Cancer: Biological and Methodological Considerations Journal of Clinical Pathology. Mar, 2011 | Pubmed ID: 21177747 MDM2 Gene Amplification and Protein Expressions in Colon Carcinoma: is Targeting MDM2 a New Therapeutic Option? Virchows Archiv : an International Journal of Pathology. Feb, 2011 | Pubmed ID: 21113617 Recognition of Cellular Implants by the Brain's Innate Immune System Immunology and Cell Biology. May, 2011 | Pubmed ID: 21102538 The Presence of Y Chromosomal Deoxyribonucleic Acid in the Female Vaginal Swab: Possible Implications for Human Papillomavirus Testing Cancer Epidemiology. Feb, 2011 | Pubmed ID: 21095173 Clinical Potential of Intravenous Neural Stem Cell Delivery for Treatment of Neuroinflammatory Disease in Mice? Cell Transplantation. 2011 | Pubmed ID: 21092405 Postextubation Obstructive Pseudomembranes: a Case Series and Review of a Rare Complication After Endotracheal Intubation Lung. Feb, 2011 | Pubmed ID: 21082188 Array-based DNA Methylation Profiling for Breast Cancer Subtype Discrimination PloS One. 2010 | Pubmed ID: 20830311 Effect of the Secretory Small GTPase Rab27B on Breast Cancer Growth, Invasion, and Metastasis Journal of the National Cancer Institute. Jun, 2010 | Pubmed ID: 20484105 Epidermal Growth Factor Receptor and K-RAS Status in Two Cohorts of Squamous Cell Carcinomas BMC Cancer. 2010 | Pubmed ID: 20459770 Carbonic Anhydrase IX Expression Correlates with FDG Uptake by Primary Non-small Cell Lung Cancer Cancer Biotherapy & Radiopharmaceuticals. Apr, 2010 | Pubmed ID: 20423227 Clear-cell Variant of Solid-pseudopapillary Neoplasm of the Pancreas: a Case Report and Review of the Literature The Malaysian Journal of Pathology. Dec, 2009 | Pubmed ID: 20514858 Prognostic Role of Vasculogenic Mimicry in Colorectal Cancer Diseases of the Colon and Rectum. Dec, 2009 | Pubmed ID: 19934926 Combined Effect of EPO and Radiotherapy on the Expression of Endogenous Molecular Markers of Tumor Metabolism and Metastasis Cancer Biotherapy & Radiopharmaceuticals. Oct, 2009 | Pubmed ID: 19877886 Re: Infrequent SMARCB1/INI1 Gene Alteration in Epithelioid Sarcoma: a Useful Tool in Distinguishing Epithelioid Sarcoma from Malignant Rhabdoid Tumor: Direct Evidence of Mutational Inactivation of SMARCB1/INI1 in Epithelioid Sarcoma Human Pathology. Sep, 2009 | Pubmed ID: 19683621 Expression of Hexokinases and Glucose Transporters in Treated and Untreated Oesophageal Adenocarcinoma Histology and Histopathology. Aug, 2009 | Pubmed ID: 19554504 The Extracellular Matrix Regulates Cancer Progression and Therapy Response: Implications for Prognosis and Treatment Current Pharmaceutical Design. 2009 | Pubmed ID: 19355975 Expression of SGLT1, Bcl-2 and P53 in Primary Pancreatic Cancer Related to Survival Cancer Investigation. Oct, 2008 | Pubmed ID: 18853313 Re: Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach The American Journal of Surgical Pathology. Dec, 2008 | Pubmed ID: 18824897 Molecular and Pathological Signatures of Epithelial-mesenchymal Transitions at the Cancer Invasion Front Histochemistry and Cell Biology. Sep, 2008 | Pubmed ID: 18648847 Differential Impact of TGF-beta and EGF on Fibroblast Differentiation and Invasion Reciprocally Promotes Colon Cancer Cell Invasion Cancer Letters. Aug, 2008 | Pubmed ID: 18423981 Gastrin-releasing Peptide Receptor Imaging in Human Breast Carcinoma Versus Immunohistochemistry Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2008 | Pubmed ID: 18199617 Detection of Beta-catenin Mutations in Paraffin-embedded Sporadic Desmoid-type Fibromatosis by Mutation-specific Restriction Enzyme Digestion (MSRED): an Ancillary Diagnostic Tool The American Journal of Surgical Pathology. Sep, 2007 | Pubmed ID: 17721184 One-stage Penectomy and Phalloplasty for Epithelioid Sarcoma of the Penis in an Adolescent: Part 2 European Urology. Jun, 2007 | Pubmed ID: 17575585 性リンパ管新生浸潤乳癌原発腫瘍部位での不在。 Cancer Letters. Aug, 2007 | Pubmed ID: 17442484 Molecular Analysis of Primary Gastric Cancer, Corresponding Xenografts, and 2 Novel Gastric Carcinoma Cell Lines Reveals Novel Alterations in Gastric Carcinogenesis Human Pathology. Jun, 2007 | Pubmed ID: 17376510 Array CGH Analysis in Primary Gastrointestinal Stromal Tumors: Cytogenetic Profile Correlates with Anatomic Site and Tumor Aggressiveness, Irrespective of Mutational Status Genes, Chromosomes & Cancer. Mar, 2007 | Pubmed ID: 17171690 One-stage Penectomy and Phalloplasty for Epithelioid Sarcoma of the Penis in an Adolescent European Urology. May, 2007 | Pubmed ID: 17095143 Differences in Imiquimod Treatment Outcome in Two Patients with Bowenoid Papulosis Containing Either Episomal or Integrated Human Papillomavirus 16 The Journal of Investigative Dermatology. Mar, 2007 | Pubmed ID: 17008876 Molecular Pathogenesis of Multiple Gastrointestinal Stromal Tumors in NF1 Patients Human Molecular Genetics. Mar, 2006 | Pubmed ID: 16461335 Inflammatory Myofibroblastic Tumor with ALK/TPM3 Fusion Presenting As Ileocolic Intussusception: an Unusual Presentation of an Unusual Neoplasm Human Pathology. Jan, 2006 | Pubmed ID: 16360423 ユーイング肉腫、低酸素によって誘導代替循環システムにおける腫瘍細胞の可塑性。 Cancer Research. Dec, 2005 | Pubmed ID: 16357161 Metastasized Angiosarcoma of the Spleen in a 2-year-old Girl Pediatric Hematology and Oncology. Jul-Aug, 2005 | Pubmed ID: 16020128 Uterine Gastrointestinal Stromal Tumour (GIST) Gynecologic Oncology. Jun, 2005 | Pubmed ID: 15943997 Differential Expression of KIT/PDGFRA Mutant Isoforms in Epithelioid and Mixed Variants of Gastrointestinal Stromal Tumors Depends Predominantly on the Tumor Site Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Aug, 2004 | Pubmed ID: 15154005 ALK-ATIC Fusion in Urinary Bladder Inflammatory Myofibroblastic Tumor Genes, Chromosomes & Cancer. Oct, 2003 | Pubmed ID: 12939746 Frequent Occurrence of BCL6 Rearrangements in Nodular Lymphocyte Predominance Hodgkin Lymphoma but Not in Classical Hodgkin Lymphoma Blood. Jan, 2003 | Pubmed ID: 12393409 Complex Genetic Alterations in Gastrointestinal Stromal Tumors with Autonomic Nerve Differentiation Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jul, 2002 | Pubmed ID: 12118105 Identification of Novel Fusion Partners of ALK, the Anaplastic Lymphoma Kinase, in Anaplastic Large-cell Lymphoma and Inflammatory Myofibroblastic Tumor Genes, Chromosomes & Cancer. Aug, 2002 | Pubmed ID: 12112524 Fluorescence in Situ Hybridization Study of Chromosome 7 Aberrations in Hepatosplenic T-cell Lymphoma: Isochromosome 7q As a Common Abnormality Accumulating in Forms with Features of Cytologic Progression Genes, Chromosomes & Cancer. Mar, 2002 | Pubmed ID: 11807981 定量PCRを通じて非小細胞肺癌(NSCLC)患者の血漿中のエキソソームのmiRNA解析:実行可能な液体生検ツール Marco Giallombardo*1,2, Jorge Chacártegui Borrás*2,3, Marta Castiglia4, Nele Van Der Steen3, Inge Mertens5,6, Patrick Pauwels7,3, Marc Peeters8,3, Christian Rolfo2,3 1Department of Biopathology and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, 2Phase I-Early Clinical Trials Unit, Oncology Department, Antwerp University Hospital (UZA), 3Center for Oncological Research (CORE), Antwerp University, 4Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 5Flemish Institute for Technological Research (VITO), 6CORE, Campus Groenenborger, Antwerp University, 7Molecular Pathology, Pathology Department, Antwerp University Hospital (UZA), 8Oncology Department, Antwerp University Hospital (UZA) Medicine
定量PCRを通じて非小細胞肺癌(NSCLC)患者の血漿中のエキソソームのmiRNA解析:実行可能な液体生検ツール Marco Giallombardo*1,2, Jorge Chacártegui Borrás*2,3, Marta Castiglia4, Nele Van Der Steen3, Inge Mertens5,6, Patrick Pauwels7,3, Marc Peeters8,3, Christian Rolfo2,3 1Department of Biopathology and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, 2Phase I-Early Clinical Trials Unit, Oncology Department, Antwerp University Hospital (UZA), 3Center for Oncological Research (CORE), Antwerp University, 4Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 5Flemish Institute for Technological Research (VITO), 6CORE, Campus Groenenborger, Antwerp University, 7Molecular Pathology, Pathology Department, Antwerp University Hospital (UZA), 8Oncology Department, Antwerp University Hospital (UZA) Medicine