Per-Olof Berggren The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet Karolinska University Hospital Biography Publications Institution JoVE Articles Per-Olof Berggren has not added a biography. If you are Per-Olof Berggren and would like to personalize this page please email our Author Liaison for assistance. Publications Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling Biomolecules. May, 2023 | Pubmed ID: 37371464 Longitudinal Monitoring of Pancreatic Islet Damage in Streptozotocin-treated Mice with Optical Coherence Microscopy Biomedical Optics Express. Jan, 2023 | Pubmed ID: 36698658 Uncommon Transplantation Sites: Transplantation of Islets and Islet Organoids in the Anterior Chamber of the Eye of Rodents and Monkeys Methods in Molecular Biology (Clifton, N.J.). 2023 | Pubmed ID: 36507983 Novel Aspects of Intra-islet Communication: Primary Cilia and Filopodia Advances in Biological Regulation. Jan, 2023 | Pubmed ID: 36266190 Treatment of the Metabolic Syndrome by SiRNA Targeting Apolipoprotein CIII BioFactors (Oxford, England). Jan, 2023 | Pubmed ID: 36039858 ATF5 is a Regulator of ER Stress and β-cell Apoptosis in Different Mouse Models of Genetic- and Diet-induced Obesity and Diabetes Mellitus Cellular Signalling. Nov, 2022 | Pubmed ID: 36436799 Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells International Journal of Molecular Sciences. Oct, 2022 | Pubmed ID: 36293194 Mitochondrial Impairment and Intracellular Reactive Oxygen Species Alter Primary Cilia Morphology Life Science Alliance. Sep, 2022 | Pubmed ID: 36104081 Inositol Hexakisphosphate Primes Syndapin I/PACSIN 1 Activation in Endocytosis Cellular and Molecular Life Sciences : CMLS. May, 2022 | Pubmed ID: 35534740 Diversity of Respiratory Parameters and Metabolic Adaptation to Low Oxygen Tension in Mesenchymal Stromal Cells Metabolism Open. Mar, 2022 | Pubmed ID: 35528374 Inward and Outward Currents of Native and Cloned K(ATP) Channels (Kir6.2/SUR1) Share Single-channel Kinetic Properties Biochemistry and Biophysics Reports. Jul, 2022 | Pubmed ID: 35434386 Intravital Ca Imaging of Pancreatic β Cell Function After Bariatric Surgery Cell Calcium. Jun, 2022 | Pubmed ID: 35278937 Destabilization of β Cell FIT2 by Saturated Fatty Acids Alter Lipid Droplet Numbers and Contribute to ER Stress and Diabetes Proceedings of the National Academy of Sciences of the United States of America. Mar, 2022 | Pubmed ID: 35254894 Intracameral Microimaging of Maturation of Human IPSC Derivatives into Islet Endocrine Cells Cell Transplantation. 2022 | Pubmed ID: 35156411 Apolipoprotein CIII Reduction Protects White Adipose Tissues Against Obesity-Induced Inflammation and Insulin Resistance in Mice International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008488 An Integrative Proteomics Method Identifies a Regulator of Translation During Stem Cell Maintenance and Differentiation Nature Communications. Nov, 2021 | Pubmed ID: 34772928 Expression of Truncated Kir6.2 Promotes Insertion of Functionally Inverted ATP-sensitive K Channels Scientific Reports. Nov, 2021 | Pubmed ID: 34728728 Challenges in Stem Cell-derived Islet Replacement Therapy Can Be Overcome Cell Transplantation. 2021 | Pubmed ID: 34565192 Tissue-specific Expression of Insulin Receptor Isoforms in Obesity/type 2 Diabetes Mouse Models Journal of Cellular and Molecular Medicine. May, 2021 | Pubmed ID: 33742502 Lowering Apolipoprotein CIII Protects Against High-fat Diet-induced Metabolic Derangements Science Advances. Mar, 2021 | Pubmed ID: 33712458 Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33477763 XPR1 Mediates the Pancreatic β-Cell Phosphate Flush Diabetes. Jan, 2021 | Pubmed ID: 32826297 Integration of Primary Endocrine Cells and Supportive Cells Using Functionalized Silk Promotes the Formation of Prevascularized Islet-like Clusters ACS Biomaterials Science & Engineering. Feb, 2020 | Pubmed ID: 33464872 Islet Vascularization is Regulated by Primary Endothelial Cilia Via VEGF-A-dependent Signaling ELife. Nov, 2020 | Pubmed ID: 33200981 Studying the Biology of Cytotoxic T Lymphocytes in Vivo with a Fluorescent Granzyme B-mTFP Knock-in Mouse ELife. Jul, 2020 | Pubmed ID: 32696761 Platelet Factor 4 Enhances CD4 T Effector Memory Cell Responses Via Akt-PGC1α-TFAM Signaling-mediated Mitochondrial Biogenesis Journal of Thrombosis and Haemostasis : JTH. Oct, 2020 | Pubmed ID: 32671959 Modelling of Dysregulated Glucagon Secretion in Type 2 Diabetes by Considering Mitochondrial Alterations in Pancreatic α-cells Royal Society Open Science. Jan, 2020 | Pubmed ID: 32218947 Enhanced Expression of β Cell Ca3.1 Channels Impairs Insulin Release and Glucose Homeostasis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2020 | Pubmed ID: 31871187 Intraocular Pressure Monitoring Following Islet Transplantation to the Anterior Chamber of the Eye Nano Letters. Mar, 2020 | Pubmed ID: 31750664 IgGs from Patients with Amyotrophic Lateral Sclerosis and Diabetes Target Caαδ1 Subunits Impairing Islet Cell Function and Survival Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31826954 Noninvasive Intravital High-resolution Imaging of Pancreatic Neuroendocrine Tumours Scientific Reports. Oct, 2019 | Pubmed ID: 31601958 Author Correction: Structural Basis for Delta Cell Paracrine Regulation in Pancreatic Islets Nature Communications. Sep, 2019 | Pubmed ID: 31511521 Structural Basis for Delta Cell Paracrine Regulation in Pancreatic Islets Nature Communications. Aug, 2019 | Pubmed ID: 31420552 Correction To: In Vivo Imaging of Type 1 Diabetes Immunopathology Using Eye-transplanted Islets in NOD Mice Diabetologia. Aug, 2019 | Pubmed ID: 31190158 In Vivo Imaging of Type 1 Diabetes Immunopathology Using Eye-transplanted Islets in NOD Mice Diabetologia. Jul, 2019 | Pubmed ID: 31087105 Assembly of Functionalized Silk Together with Cells to Obtain Proliferative 3D Cultures Integrated in a Network of ECM-like Microfibers Scientific Reports. Apr, 2019 | Pubmed ID: 31000733 Local Release of Rapamycin by Microparticles Delays Islet Rejection Within the Anterior Chamber of the Eye Scientific Reports. Mar, 2019 | Pubmed ID: 30850640 Inositol Pyrophosphates and Akt/PKB: Is the Pancreatic β-cell the Exception to the Rule? Cellular Signalling. Jun, 2019 | Pubmed ID: 30742888 Operational Immune Tolerance Towards Transplanted Allogeneic Pancreatic Islets in Mice and a Non-human Primate Diabetologia. 05, 2019 | Pubmed ID: 30701283 The Eye As a Novel Imaging Site in Diabetes Research Pharmacology & Therapeutics. May, 2019 | Pubmed ID: 30677477 MiR-31 Regulates Energy Metabolism and is Suppressed in T cells from Patients with Sjögren's Syndrome European Journal of Immunology. Feb, 2019 | Pubmed ID: 30307034 Neither Polyphenol-rich Red Wine nor Fenofibrate Affects the Onset of Type-1 Diabetes Mellitus in the BB Rat Laboratory Animal Research. Sep, 2018 | Pubmed ID: 30310409 Blocking Ca Channel β Subunit Reverses Diabetes Cell Reports. Jul, 2018 | Pubmed ID: 30044988 Corrigendum to 'Inositol Hexakisphosphate Kinase 1 is a Metabolic Sensor in Pancreatic β-cells' [Cellular Signalling 46 (2018) 120-128] Cellular Signalling. May, 2018 | Pubmed ID: 29807098 Inositol Hexakisphosphate Kinase 1 is a Metabolic Sensor in Pancreatic β-cells Cellular Signalling. Jun, 2018 | Pubmed ID: 29522819 Paracrine Interactions Within the Pancreatic Islet Determine the Glycemic Set Point Cell Metabolism. Mar, 2018 | Pubmed ID: 29514065 Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation Cell Metabolism. Feb, 2018 | Pubmed ID: 29414686 Protein Kinase- and Lipase Inhibitors of Inositide Metabolism Deplete IP Indirectly in Pancreatic β-cells: Off-target Effects on Cellular Bioenergetics and Direct Effects on IP6K Activity Cellular Signalling. Jan, 2018 | Pubmed ID: 29042286 Inhibition of C1-Ten PTPase Activity Reduces Insulin Resistance Through IRS-1 and AMPK Pathways Scientific Reports. Dec, 2017 | Pubmed ID: 29259227 Kinetics of Functional Beta Cell Mass Decay in a Diphtheria Toxin Receptor Mouse Model of Diabetes Scientific Reports. Sep, 2017 | Pubmed ID: 28963457 Pancreatic Islet Blood Flow Dynamics in Primates Cell Reports. Aug, 2017 | Pubmed ID: 28793270 A Novel Toolbox to Investigate Tissue Spatial Organization Applied to the Study of the Islets of Langerhans Scientific Reports. Mar, 2017 | Pubmed ID: 28303903 Preservation of Anticancer and Immunosuppressive Properties of Rapamycin Achieved Through Controlled Releasing Particles AAPS PharmSciTech. Oct, 2017 | Pubmed ID: 28251512 Apolipoprotein CIII is a New Player in Diabetes Current Opinion in Lipidology. Feb, 2017 | Pubmed ID: 27875339 Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells Cell Reports. Dec, 2016 | Pubmed ID: 28009296 The Different Faces of the Pancreatic Islet Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27586419 Diabetes Prevention Through Antiviral Treatment in Biobreeding Rats Viral Immunology. Oct, 2016 | Pubmed ID: 27505258 The Imidazoline Compound RX871024 Promotes Insulinoma Cell Death Independent of AMP-activated Protein Kinase Inhibition Investigational New Drugs. Aug, 2016 | Pubmed ID: 27221730 Silk Matrices Promote Formation of Insulin-secreting Islet-like Clusters Biomaterials. Jun, 2016 | Pubmed ID: 26986856 TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in HMSCs Scientific Reports. Mar, 2016 | Pubmed ID: 26980664 Liraglutide Compromises Pancreatic β Cell Function in a Humanized Mouse Model Cell Metabolism. Mar, 2016 | Pubmed ID: 26876561 The Anterior Chamber of the Eye is a Transplantation Site That Supports and Enables Visualisation of Beta Cell Development in Mice Diabetologia. May, 2016 | Pubmed ID: 26847769 ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats Molecular Medicine (Cambridge, Mass.). May, 2016 | Pubmed ID: 26736179 PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation Cell Reports. Oct, 2015 | Pubmed ID: 26387957 Spatial and Temporal Coordination of Insulin Granule Exocytosis in Intact Human Pancreatic Islets Diabetologia. Dec, 2015 | Pubmed ID: 26376795 Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins PLoS Genetics. Sep, 2015 | Pubmed ID: 26352669 New Insights into the Architecture of the Islet of Langerhans: a Focused Cross-species Assessment Diabetologia. Oct, 2015 | Pubmed ID: 26215305 Glucose Intolerance and Pancreatic β-cell Dysfunction in the Anorectic Anx/anx Mouse American Journal of Physiology. Endocrinology and Metabolism. Aug, 2015 | Pubmed ID: 26126683 The Pancreatic β-cell in Deadly Encounter with Apolipoprotein CIII Cell Cycle (Georgetown, Tex.). 2015 | Pubmed ID: 26102210 Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices PloS One. 2015 | Pubmed ID: 26090859 Secretome Protein Signature of Human Gastrointestinal Stromal Tumor Cells Experimental Cell Research. Aug, 2015 | Pubmed ID: 25983130 Apolipoprotein CIII Links Islet Insulin Resistance to β-cell Failure in Diabetes Proceedings of the National Academy of Sciences of the United States of America. May, 2015 | Pubmed ID: 25941406 Regulation of Glucose Homeostasis Using Radiogenetics and Magnetogenetics in Mice Nature Medicine. Jan, 2015 | Pubmed ID: 25569545 β-Cell Ca(2+) Dynamics and Function Are Compromised in Aging Advances in Biological Regulation. Jan, 2015 | Pubmed ID: 25282681 Young Capillary Vessels Rejuvenate Aged Pancreatic Islets Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25404292 Ciliary Dysfunction Impairs Beta-cell Insulin Secretion and Promotes Development of Type 2 Diabetes in Rodents Nature Communications. 2014 | Pubmed ID: 25374274 Defects in β-cell Ca2+ Dynamics in Age-induced Diabetes Diabetes. Dec, 2014 | Pubmed ID: 24985350 Contribution of Endothelial Injury and Inflammation in Early Phase to Vein Graft Failure: the Causal Factors Impact on the Development of Intimal Hyperplasia in Murine Models PloS One. 2014 | Pubmed ID: 24887332 Short and Prolonged Exposure to Hyperglycaemia in Human Fibroblasts and Endothelial Cells: Metabolic and Osmotic Effects The International Journal of Biochemistry & Cell Biology. Aug, 2014 | Pubmed ID: 24814290 Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet Diabetes. Aug, 2014 | Pubmed ID: 24658304 AP2-Cre-mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra PloS One. 2014 | Pubmed ID: 24416430 Reporter Islets in the Eye Reveal the Plasticity of the Endocrine Pancreas Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24248353 Islet Inflammation in Plain Sight Diabetes, Obesity & Metabolism. Sep, 2013 | Pubmed ID: 24003927 Evidence for Ca(2+)-regulated ATP Release in Gastrointestinal Stromal Tumors Experimental Cell Research. May, 2013 | Pubmed ID: 23499741 Signalisieren Von Östrogen Und Das Metabolische Syndrom: Ausrichtung Der Leber Östrogen-Rezeptor Alpha-Aktion PloS One. 2013 | Pubmed ID: 23451233 Neue Horizonte in Der Zellulären Verordnung Von Inositol Polyphosphates: Erkenntnisse Aus Der Bauchspeicheldrüse β-Zelle Pharmacological Reviews. 2013 | Pubmed ID: 23429059 C1-Ten Ist Ein Protein Tyrosin Phosphatase Des IRS-1, Regulierung Der IRS-1 Stabilität Und Muskelschwund Molecular and Cellular Biology. Feb, 2013 | Pubmed ID: 23401856 Emodin Reguliert Glukose-Auslastung Durch Die Aktivierung Der AMP-aktivierte Proteinkinase The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23303186 Das Pankreas Inselchen Als Drehscheibe Signalisierung Advances in Biological Regulation. Jan, 2013 | Pubmed ID: 23073565 Lokalisierung Von Cholesterin, Amyloid Und Glia in Alzheimer-Krankheit Transgenen Maus Hirngewebe Mit Time-of-Flight Sekundärionen-Massenspektrometrie (ToF-SIMS) Und Immunfluoreszenz-Imaging Acta Neuropathologica. Jan, 2013 | Pubmed ID: 22996963 Nicht-invasive in Vivo Modell Zeigen Die Auswirkungen Der Vegetativen Innervation Auf Pankreas Inselchen-Funktion Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23236142 Glukagon Reguliert Seine Eigene Synthese Von Autocrine Signalisieren Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23213228 Die Betazellen Als Paradigma Für Fortschritte in Der Inositide Forschung Advances in Biological Regulation. Sep, 2012 | Pubmed ID: 22884029 Inosit Hexakisphosphate Unterdrückt Exzitatorischen Neurotransmission über Synaptotagmin-1 C2B Domäne in Der Hippocampal Neuronen Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22778403 Dynamin-vermittelte Nephrin Phosphorylierung Reguliert Glukose Stimuliert Insulin-Freisetzung in Pankreatischen Betazellen The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22718751 Echtzeiterkennung Von Acetylcholin Release Von Menschlichen Pankreas Nature Protocols. Jun, 2012 | Pubmed ID: 22555241 Deutlich Verringerte Durchblutung Pankreatischen Kleinen Inseln, Die Intraportally in Der Leber Transplantiert: Unterbrechung Der Inselchen Integrität Für Inselchen Revascularization Notwendig Diabetes. Mar, 2012 | Pubmed ID: 22315321 Einstufige Reinigung Der Funktionale Mensch Und Ratte Pankreas Alphazellen Integrative Biology : Quantitative Biosciences from Nano to Macro. Feb, 2012 | Pubmed ID: 22267247 Transthyretin Bindet an Proteine Glukose-reguliert Und Unterliegt Endozytose Von Der Pankreas β-Zelle Cellular and Molecular Life Sciences : CMLS. May, 2012 | Pubmed ID: 22183612 Spender Endothelial Inselzellen Im Pankreas Inselchen Revascularization Diabetes. Oct, 2011 | Pubmed ID: 21873551 Hochauflösende, Nichtinvasiven Längs Live Bildgebung Immunantworten Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21768391 Innervation Muster Der Autonome Axone Im Menschlichen Pankreas Cell Metabolism. Jul, 2011 | Pubmed ID: 21723503 Apolipoprotein CIII Reduziert Proinflammatory Cytokine-induzierte Apoptose in Ratte Pankreas Inseln über Die Akt-prosurvival-Bahn Endocrinology. Aug, 2011 | Pubmed ID: 21693679 Munc18-1 Und Munc18-2 Proteine Modulieren Beta-Zellen Ca2 + Empfindlichkeit Und Kinetik Der Insulin-Exozytose Anders The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21690086 Alpha-Zellen Sezernieren Acetylcholin Als Nicht-neuronale Parakrine Signal Grundierung Beta-Zelle Funktion Beim Menschen Nature Medicine. Jul, 2011 | Pubmed ID: 21685896 Senkung Der Apolipoprotein CIII Verzögerungen Auftreten Von Typ 1 Diabetes Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21670290 Kurze Telomere β-Zelle Signalisieren Und Überleben Gefährden PloS One. 2011 | Pubmed ID: 21423765 Electrical Kurzschluss in Den β-Zellen Eines Patienten Mit Nicht-Insulinom Pancreatogenous Blutzuckersenkende-Syndrom (NIPHS): Ein Fallbericht Journal of Medical Case Reports. 2010 | Pubmed ID: 20863385 Interleukin-6 Signalisieren in Leber Parenchymal Zellen Unterdrückt Leber Entzündungen Und Verbessert Die Systemische Insulinwirkung Cell Metabolism. Sep, 2010 | Pubmed ID: 20816090 Diphosphosinositol Polyphosphates Und Energiestoffwechsel: Assay Für ATP/ADP-Verhältnis Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645185 HPLC-Trennung Von Inosit Polyphosphates Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645179 Die Rolle Von Inositol Und Die Grundsätze Der Etikettierung, Extraktion Und Analyse Der Inositides in Den Säugetier-Zellen Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645178 Neuartige Aspekte Auf Betazellen-Signaltransduktion Biochemical and Biophysical Research Communications. May, 2010 | Pubmed ID: 20494121 ATP-Gating P2X3 Rezeptoren Bilden Eine Positive Autocrine Signal Für Insulin-Freisetzung in Die Menschlichen Betazellen Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308565 Cholinerge Vermehrung Des Insulin-Freisetzung Erfordert Ankyrin-B Science Signaling. 2010 | Pubmed ID: 20234002 Insulin-Rückmeldung Per PI3K-C2alpha Aktiviert PKBalpha/Akt1 Ist Erforderlich Für Glukose Stimuliert Insulin-Sekretion FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010 | Pubmed ID: 20061534 Lipotoxizität Und Verminderte Inselchen Pfropfen überleben Diabetes Care. Mar, 2010 | Pubmed ID: 20009097 Nephrin Drückt Sich Auf Der Oberfläche Des Insulin-Vesikeln Und Ermöglicht Glukose Stimuliert Insulin-Freisetzung Diabetes. Jan, 2010 | Pubmed ID: 19833886 Membran Hemifusion Erleichtert Die Zugkraft Von Interagierenden SNAREs Generiert Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2009 | Pubmed ID: 20023730 Antivirale Behandlungen Schwere Diabetes Ljungan Infizierte CD-1 Mäusen Und Verzögerung Auftreten Bei Diabetes-gefährdeten BB-Ratten Microbiology and Immunology. Oct, 2009 | Pubmed ID: 19780970 Entstörer Der Cytokine Signaling-1 Hemmt Die Aktivierung Der Caspase Und Schützt Vor Zytokin-induced Beta-Zellentod Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19763396 Inosit Pyrophosphates: Struktur, Enzymologie Und Funktion Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19714294 Diphosphoinositol Pentakisphosphate Als Neuartige Vermittler Der Exozytose Von Insulin Advances in Enzyme Regulation. 2009 | Pubmed ID: 19534030 Positive Rolle Des Pankreas Mikromilieu Für Angiogenesis in Transplantierten Bauchspeicheldrüse Inselchen Cell Transplantation. 2009 | Pubmed ID: 19476206 Suramin Hemmt Die CD40-CD154 Kostimulatorischen Interaktion: Einen Möglichen Mechanismus Für Immunsuppressive Effekte Biochemical Pharmacology. Apr, 2009 | Pubmed ID: 19283894 Eine Alte Duplizierung Von Exon 5 Im Snap25-gen Ist Für Komplexe Neuronale Entwicklung/Funktion Erforderlich PLoS Genetics. Nov, 2008 | Pubmed ID: 19043548 Nicht-invasive Hochauflösende In-vivo Bildgebung Der Zellbiologie in Der Vorderkammer Des Auges Maus Nature Protocols. 2008 | Pubmed ID: 18714296 Echtzeitüberwachung Der Apoptose Durch Caspase-3-ähnliche Protease Induzierte FRET-Reduzierung Durch Amyloid Aggregation Ausgelöst Experimental Diabetes Research. 2008 | Pubmed ID: 18566681 Glutamat Ist Ein Positiver Autocrine Signal Für Glukagon-Release Cell Metabolism. Jun, 2008 | Pubmed ID: 18522835 Insulin in Den Betazellen Signalisieren Annual Review of Nutrition. 2008 | Pubmed ID: 18481923 Activin B-Rezeptor ALK7 Ist Ein Negativer Regulator Der Betazellen-Funktion Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18480258 Proteine in Der Insulin-sezernierende Zelle Zeile MIN6 Bind Die Imidazoline Zusammengesetzte BL11282 FEBS Letters. May, 2008 | Pubmed ID: 18420036 Automatisierte Hochdurchsatz-Assays Für Die Bewertung Der Menschlichen Pankreas Inselchen-Funktion Cell Transplantation. 2008 | Pubmed ID: 18351020 Professor Rolf Luft, 1914--2007 Diabetologia. May, 2008 | Pubmed ID: 18327565 Nicht-invasive In-vivo Bildgebung Des Pankreas Inselchen Zellbiologie Nature Medicine. May, 2008 | Pubmed ID: 18327249 Eine Schlüsselrolle Für Phosphorylierte Inosit-Compounds in Betazellen-Reiz-Sekretion Kupplung Advances in Enzyme Regulation. 2008 | Pubmed ID: 18194673 Anforderungen an Inosit Pyrophosphates Für Volle Exocytotic Kapazität in Pankreatischen Betazellen Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 18033884 Verteilung Der Intraportally Implantierten Mikrosphären Und Fluoreszierende Inselchen in Den Mäusen Cell Transplantation. 2007 | Pubmed ID: 17912953 Glukose Rekruten K(ATP) Kanäle über Nicht-Insulin-haltige Dichten Kern-Granulat Cell Metabolism. Sep, 2007 | Pubmed ID: 17767908 Interferenzen Mit Gewebe-Faktor Verlängert Intrahepatische Inselchen Allograft Überleben in Einem Nicht-menschlichen Primaten Marginal Masse Modell Transplantation. Aug, 2007 | Pubmed ID: 17700154 3 H-Serotonin Als Eine Markierung Der Oszillierende Insulin-Sekretion in Klonalen Beta-Zellen (INS-1) FEBS Letters. Aug, 2007 | Pubmed ID: 17686476 Eine Feedback-Schleife, Autocrine Insulin Unterhält Betazellen-3-phosphoryliert Inosit Lipide Molecular Endocrinology (Baltimore, Md.). Nov, 2007 | Pubmed ID: 17652185 Gewebe-abhängige Verlust Von Phosphofructokinase-M Bei Mäusen Mit Unterbrochenen Tätigkeit Des Distalen Projektträgers: Beeinträchtigung Der Insulin-Sekretion American Journal of Physiology. Endocrinology and Metabolism. Sep, 2007 | Pubmed ID: 17595219 Einnistung Website-abhängige Dysfunktion Des Transplantierten Bauchspeicheldrüse Inselchen Diabetes. Jun, 2007 | Pubmed ID: 17400931 R-Typ Ca(2+)-Kanal-hervorgerufen CICR Reguliert Glukose-induzierte Somatostatin Absonderung Nature Cell Biology. Apr, 2007 | Pubmed ID: 17369816 Selektive Genaktivierung Durch Räumliche Trennung Insulin Rezeptor B Signalisieren FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2007 | Pubmed ID: 17264162 Heraufregulation Des EGF-Rezeptor Signalisieren in Den Pankreatischen Kleinen Inseln Verursacht Diabetes Mit Eingeschränkter Postnatale Beta-Zell-Wachstum Diabetes. Dec, 2006 | Pubmed ID: 17130473 RX871024 Reduziert Keine Produktion Schützt Jedoch Nicht Gegen Betazellen-Tod Von Proinflammatory Cytokines Induziert Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16870144 Die Rolle Der Spannung-Gating Kalzium-Kanäle in Betazellen-Physiologie Und Pathophysiologie Endocrine Reviews. Oct, 2006 | Pubmed ID: 16868246 Neuartige Aspekte Der Signaltransduktion in Der Betazellen Nutrition, Metabolism, and Cardiovascular Diseases : NMCD. Mar, 2006 | Pubmed ID: 16530130 Tomosyn Wird in Beta-Zellen Exprimiert Und Negativ Reguliert Insulin Exozytose Diabetes. Mar, 2006 | Pubmed ID: 16505218 Die Einzigartige Cytoarchitecture Menschlichen Pankreas Inseln Hat Auswirkungen Auf Die Inselchen Zelle-Funktion Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16461897 Sirt1: Einem Metabolischen Hauptschalter, Die Lebensdauer Moduliert Nature Medicine. Jan, 2006 | Pubmed ID: 16397557 Transthyretin Bildet Eine Funktionale Komponente in Betazellen-Reiz-Sekretion Kupplung Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16286652 Monomer G-Protein, Rhes, Ist Kein Imidazoline Regulierte Protein in Pankreatischen Betazellen Biochemical and Biophysical Research Communications. Dec, 2005 | Pubmed ID: 16277977 Eine SIRTain Rolle in Betazellen-Funktion Cell Metabolism. Aug, 2005 | Pubmed ID: 16098824 Pankreas Inselchen-Funktion in Eine Transgene Maus Fluoreszierenden Proteins Zum Ausdruck Zu Bringen The Journal of Endocrinology. Aug, 2005 | Pubmed ID: 16079259 Endotheliale Spender-Inselzellen Beteiligen Sich an Der Bildung Von Funktionalen Schiffe Innerhalb Pankreas Inselchen Transplantationen Diabetes. Aug, 2005 | Pubmed ID: 16046293 Neuronale Kalzium Sensor-1 Spurenelement Glukose-abhängige Exozytose in Pankreatischen Betazellen Durch Aktivierung Der Phosphatidylinositol-4-Kinase-Beta Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16014415 Eine Neuartige Methode Zur Beurteilung Der Zellulären Zusammensetzung Und Beta-Zell-Lebensfähigkeit in Menschlichen Inselchen Zubereitungen American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2005 | Pubmed ID: 15943621 Cyclin-abhängige Kinase 5 Aktivatoren P35 Und P39 Erleichtern Die Bildung Von Funktionalen Synapsen Brain Research. Molecular Brain Research. Aug, 2005 | Pubmed ID: 15908038 Kalzium Hat Eine Permissive Rolle in Interleukin-1beta-induzierte Von C-jun N-Terminal Kinase-Aktivierung in Insulin-sezernierende Zellen Endocrinology. Jul, 2005 | Pubmed ID: 15831571 DARPP-32 Und Inhibitor-1 Werden in Pankreatischen Betazellen Ausgedrückt Biochemical and Biophysical Research Communications. Apr, 2005 | Pubmed ID: 15737638 CaV2.3 Kanal Und PKClambda: Neue Spieler in Insulin-Sekretion The Journal of Clinical Investigation. Jan, 2005 | Pubmed ID: 15630435 Beta-Zellen CaV Kanal Verordnung in Physiologie Und Pathophysiologie American Journal of Physiology. Endocrinology and Metabolism. Jan, 2005 | Pubmed ID: 15585596 Glukagon Stimuliert Exozytose in Maus Und Ratte Pankreas Alpha-Zellen Durch Bindung an Rezeptoren Glukagon Molecular Endocrinology (Baltimore, Md.). Jan, 2005 | Pubmed ID: 15459251 ATP-Sensitive K + Kanal-abhängige Verordnung Glukagon Freisetzung Und Elektrische Aktivität Von Glukose in Wildtyp Und SUR1-/-Maus Alpha-Zellen Diabetes. Dec, 2004 | Pubmed ID: 15561909 Entfernung Von Ca2 + Kanal Beta3 Untereinheit Erhöht Ca2 + Schwingungsfrequenz Und Exozytose Von Insulin Cell. Oct, 2004 | Pubmed ID: 15479643 Mint1, Ein Protein Munc-18-Interaktion Ist in Beta-Zellen Insulin-sezernierende Ausgedrückt Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15240107 Apolipoprotein CIII Fördert Ca2 +-abhängige Beta-Zellentod Im Typ 1 Diabetes Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15210953 Cyclin-abhängige Kinase 5 Zugeordnete P39 Fördert Munc18-1-Phosphorylierung Und Ca(2+)-abhängige Exozytose The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15123626 Wachstumshormon Fördert Ca(2+)-induced Ca2 + Release Im Insulin-sezernierende Zellen Durch Ryanodin-Rezeptor-Tyrosin-Phosphorylierung Molecular Endocrinology (Baltimore, Md.). Jul, 2004 | Pubmed ID: 15056730 Isoform-spezifische Insulin Rezeptor Signalisierung Umfasst Verschiedene Plasmamembran Domänen The Journal of Cell Biology. Dec, 2003 | Pubmed ID: 14691140 Online-Prüfung Von Apoptosis in Den Insulin-sezernierende Zellen Diabetes. Dec, 2003 | Pubmed ID: 14633855 Sulfonylureas Kreuz Schnell Phospholipid Bilayer Membranen Einen Gratis-Verbreitung-Mechanismus Diabetes. Oct, 2003 | Pubmed ID: 14514636 Zytosolische Mehrere Inosit Polyphosphate Phosphatase Bei Der Regulierung Der Zytoplasmatischen Freie Ca2 + Konzentration The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12963730 Schnelle Zuordnung Der Proteinkinase C-Epsilon Mit Insulin-Granulat Ist Essentiell Für Die Exozytose Von Insulin The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12941947 Dihydroxyaceton-induzierte Schwingungen in Zytoplasmatischen Freie Ca2 + Und Das ATP/ADP-Verhältnis in Beta-Zellen Mit Substimulatory Glukose Pankreas The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917415 Unterdrückung Der Beta-Zelle Stoffwechsel Und Insulin Energiefreisetzung Von PGC-1alpha Developmental Cell. Jul, 2003 | Pubmed ID: 12852853 Beteiligung Der Proteinkinase C-Epsilon in Inosit Hexakisphosphate Induziert Exozytose in Maus Pankreatischen Betazellen The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12837755 Phosphatidylinositol-4-Kinase Dient Als Metabolische Sensor Und Reguliert Die Grundierung Sekretorisches Granulat in Pankreatischen Betazellen Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12700357 Glibenclamid Hemmt Inselchen Carnitin Palmitoyltransferase 1 Aktivität, Zu PKC-abhängige Insulin Exozytose Führt American Journal of Physiology. Endocrinology and Metabolism. Aug, 2003 | Pubmed ID: 12684219 SUR1 Regelt PKA-unabhängige Lager-induzierte Untermodul Grundierung in Maus Pankreatischen B-Zellen The Journal of General Physiology. Mar, 2003 | Pubmed ID: 12601083 Zwei Generationen Von Insulinotropic Imidazoline Verbindungen Diabetes. Dec, 2002 | Pubmed ID: 12475789 Rückmeldungen Insulinwirkung Betazellen-Funktion FEBS Letters. Dec, 2002 | Pubmed ID: 12459452 Glukose-Metaboliten Hemmen Protein-Phosphatasen Und Exozytose Von Insulin Im Pankreas-Beta-Zellen Direkt Fördern Endocrinology. Dec, 2002 | Pubmed ID: 12446586 Phosphoryliert Inosit Verbindungen in Der Beta-Zelle-Stimulus-Antwort-Kupplung American Journal of Physiology. Endocrinology and Metabolism. Dec, 2002 | Pubmed ID: 12424101 Anstieg Zellulären Glutamat Regt Exozytose in Pankreatischen Betazellen FEBS Letters. Nov, 2002 | Pubmed ID: 12417312 Relevanz Von Dopamin Signalen Dynamin-2 in Der Plasmamembran Verankern Während Na +, K +-ATPase Endozytose The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12205083 Sulfonylharnstoff-Rezeptor Typ 1 Knock-out-Mäuse Haben Intakte Fütterung-stimuliert Insulin-Sekretion Trotz Deutlichen Beeinträchtigung in Ihrer Reaktion Auf Glukose The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12149271 Inosit Hexakisphosphate Fördert Dynamin Ich-vermittelte Endozytose Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12011438 Modulation Der L-förmige Ca(2+) Channels Von Unterschiedlichen Domänen Innerhalb SNAP-25 Diabetes. May, 2002 | Pubmed ID: 11978639 Unten-geregelt Ausdruck Exocytotic Proteine in Pankreas Inselchen Von Diabetischen Ratten in GK Biochemical and Biophysical Research Communications. Mar, 2002 | Pubmed ID: 11866470 Tyrosin 537 Innerhalb Der Na +, K +-ATPase Alpha-Untereinheit Ist Wesentlich Für Die AP-2 Bindung Und Clathrin-abhängige Endozytose The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11859087 Insulinotropic Aktivität Der Imidazoline Ableitung RX871024 Bei Diabetischen Ratten GK American Journal of Physiology. Endocrinology and Metabolism. Jan, 2002 | Pubmed ID: 11739091 Author Spotlight: Harnessing Mouse Eye Chambers for Noninvasive Liver Spheroid Studies Francesca Lazzeri-Barcelo1, Pierpaolo Ciardo1, Barbara Leibiger1, Ingo B. Leibiger1, Per-Olof Berggren*1,2,3, Noah Moruzzi*1 1The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 2Tecnológico de Monterrey, 3Diabetes Research Institute, Miller School of Medicine, University of Miami JoVE 66234 Biology Co-Immunopräzipitation Assay mit endogenen nuklearen Proteinen aus Zellen kultiviert unter hypoxischen Bedingungen Xiaofeng Zheng1,2, Calvin Qing Wei Ho1, Xiaowei Zheng3, Kian Leong Lee4, Katarina Gradin5, Teresa S. Pereira3, Per-Olof Berggren1,2,3, Yusuf Ali1,2 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute (SERI), Singapore General Hospital, 3The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 4Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 5Department of Cell and Molecular Biology, Karolinska Institutet JoVE 57836 Biology Transplantation in die Vorderkammer des Auges für Längs-, Non-invasive Midhat H. Abdulreda1,2, Alejandro Caicedo1,3,4, Per-Olof Berggren1,5 1Diabetes Research Institute, University of Miami Miller School of Medicine, 2Department of Surgery, University of Miami Miller School of Medicine, 3Department of Medicine, University of Miami Miller School of Medicine, 4Department of Physiology & Biophysics, University of Miami Miller School of Medicine, 5The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet JoVE 50466 Medicine
Author Spotlight: Harnessing Mouse Eye Chambers for Noninvasive Liver Spheroid Studies Francesca Lazzeri-Barcelo1, Pierpaolo Ciardo1, Barbara Leibiger1, Ingo B. Leibiger1, Per-Olof Berggren*1,2,3, Noah Moruzzi*1 1The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 2Tecnológico de Monterrey, 3Diabetes Research Institute, Miller School of Medicine, University of Miami JoVE 66234 Biology
Co-Immunopräzipitation Assay mit endogenen nuklearen Proteinen aus Zellen kultiviert unter hypoxischen Bedingungen Xiaofeng Zheng1,2, Calvin Qing Wei Ho1, Xiaowei Zheng3, Kian Leong Lee4, Katarina Gradin5, Teresa S. Pereira3, Per-Olof Berggren1,2,3, Yusuf Ali1,2 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute (SERI), Singapore General Hospital, 3The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 4Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 5Department of Cell and Molecular Biology, Karolinska Institutet JoVE 57836 Biology
Transplantation in die Vorderkammer des Auges für Längs-, Non-invasive Midhat H. Abdulreda1,2, Alejandro Caicedo1,3,4, Per-Olof Berggren1,5 1Diabetes Research Institute, University of Miami Miller School of Medicine, 2Department of Surgery, University of Miami Miller School of Medicine, 3Department of Medicine, University of Miami Miller School of Medicine, 4Department of Physiology & Biophysics, University of Miami Miller School of Medicine, 5The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet JoVE 50466 Medicine