Peter J. Roy Department of Molecular Genetics University of Toronto Biography Publications Institution JoVE Articles Peter J. Roy has not added a biography. If you are Peter J. Roy and would like to personalize this page please email our Author Liaison for assistance. Publications A Survey of the Kinome Pharmacopeia Reveals Multiple Scaffolds and Targets for the Development of Novel Anthelmintics Scientific Reports. 04, 2021 | Pubmed ID: 33911106 Author Correction: Caenorhabditis Elegans is a Useful Model for Anthelmintic Discovery Nature Communications. 07, 2020 | Pubmed ID: 32709866 The Marginal Cells of the Caenorhabditis Elegans Pharynx Scavenge Cholesterol and Other Hydrophobic Small Molecules Nature Communications. 09, 2019 | Pubmed ID: 31477732 The Novel Nematicide Wact-86 Interacts with Aldicarb to Kill Nematodes PLoS Neglected Tropical Diseases. 04, 2017 | Pubmed ID: 28379972 The MADD-3 LAMMER Kinase Interacts with a P38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis Elegans PLoS Genetics. 04, 2016 | Pubmed ID: 27123983 Caenorhabditis Elegans is a Useful Model for Anthelmintic Discovery Nature Communications. Jun, 2015 | Pubmed ID: 26108372 EVA-1 Functions As an UNC-40 Co-receptor to Enhance Attraction to the MADD-4 Guidance Cue in Caenorhabditis Elegans PLoS Genetics. Aug, 2014 | Pubmed ID: 25122090 Orthosteric and Allosteric Drug Binding Sites in the Caenorhabditis Elegans Mgl-2 Metabotropic Glutamate Receptor Neuropharmacology. Sep, 2012 | Pubmed ID: 22652059 Dafadine Inhibits DAF-9 to Promote Dauer Formation and Longevity of Caenorhabditis Elegans Nature Chemical Biology. Dec, 2011 | Pubmed ID: 22057127 Compound Prioritization Methods Increase Rates of Chemical Probe Discovery in Model Organisms Chemistry & Biology. Oct, 2011 | Pubmed ID: 22035796 MADD-4 is a Secreted Cue Required for Midline-oriented Guidance in Caenorhabditis Elegans Developmental Cell. Oct, 2011 | Pubmed ID: 22014523 MADD-2, a Homolog of the Opitz Syndrome Protein MID1, Regulates Guidance to the Midline Through UNC-40 in Caenorhabditis Elegans Developmental Cell. Jun, 2010 | Pubmed ID: 20627078 A Predictive Model for Drug Bioaccumulation and Bioactivity in Caenorhabditis Elegans Nature Chemical Biology. Jul, 2010 | Pubmed ID: 20512140 Identification of Small Molecule Inhibitors of Pseudomonas Aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen PLoS Genetics. Feb, 2008 | Pubmed ID: 18454192 A Global Analysis of Genetic Interactions in Caenorhabditis Elegans Journal of Biology. 2007 | Pubmed ID: 17897480 Cell-specific Microarray Profiling Experiments Reveal a Comprehensive Picture of Gene Expression in the C. Elegans Nervous System Genome Biology. 2007 | Pubmed ID: 17612406 High-throughput Screening of Small Molecules for Bioactivity and Target Identification in Caenorhabditis Elegans Nature Protocols. 2006 | Pubmed ID: 17487175 A Small-molecule Screen in C. Elegans Yields a New Calcium Channel Antagonist Nature. May, 2006 | Pubmed ID: 16672971 FGF Negatively Regulates Muscle Membrane Extension in Caenorhabditis Elegans Development (Cambridge, England). Apr, 2006 | Pubmed ID: 16495308 Network News: Functional Modules Revealed During Early Embryogenesis in C. Elegans Developmental Cell. Sep, 2005 | Pubmed ID: 16139218 Muscle Arm Development in Caenorhabditis Elegans Development (Cambridge, England). Jul, 2005 | Pubmed ID: 15930100 The Forkhead Transcription Factor UNC-130 is Required for the Graded Spatial Expression of the UNC-129 TGF-beta Guidance Factor in C. Elegans Genes & Development. Oct, 2000 | Pubmed ID: 11018016 Culturing and Screening the Plant Parasitic Nematode Ditylenchus dipsaci Savina R. Cammalleri1,2,3, Jessica Knox1,3, Peter J. Roy1,3,4 1Department of Molecular Genetics, University of Toronto, 2Department of Biochemistry, University of Toronto, 3The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 4Department of Pharmacology and Toxicology, University of Toronto JoVE 63438 Biology
Culturing and Screening the Plant Parasitic Nematode Ditylenchus dipsaci Savina R. Cammalleri1,2,3, Jessica Knox1,3, Peter J. Roy1,3,4 1Department of Molecular Genetics, University of Toronto, 2Department of Biochemistry, University of Toronto, 3The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 4Department of Pharmacology and Toxicology, University of Toronto JoVE 63438 Biology