Peter K. Stys Hotchkiss Brain Institute, Department of Clinical Neurosciences University of Calgary Biography Publications Institution JoVE Articles Peter K. Stys has not added a biography. If you are Peter K. Stys and would like to personalize this page please email our Author Liaison for assistance. Publications Cellular Prion Protein and NMDA Receptor Modulation: Protecting Against Excitotoxicity Frontiers in Cell and Developmental Biology. 2014 | Pubmed ID: 25364752 Editors' Preface: the Colourful White Matter Glia. Nov, 2014 | Pubmed ID: 25212954 White Matter Injury: Ischemic and Nonischemic Glia. Nov, 2014 | Pubmed ID: 25043122 Patrolling Monocytes Play a Critical Role in CX3CR1-mediated Neuroprotection During Excitotoxicity Brain Structure & Function. Apr, 2014 | Pubmed ID: 24706067 Remyelination After Spinal Cord Injury: is It a Target for Repair? Progress in Neurobiology. Jun, 2014 | Pubmed ID: 24582777 Skin-derived Precursor Schwann Cell Myelination Capacity in Focal Tibial Demyelination Muscle & Nerve. Aug, 2014 | Pubmed ID: 24282080 High-resolution Fluorescence Microscopy of Myelin Without Exogenous Probes NeuroImage. Feb, 2014 | Pubmed ID: 24188810 Treatment Trials in Progressive MS--current Challenges and Future Directions Nature Reviews. Neurology. Sep, 2013 | Pubmed ID: 23897406 Pathoetiology of Multiple Sclerosis: Are We Barking Up the Wrong Tree? F1000prime Reports. 2013 | Pubmed ID: 23755367 Metabolic Injury to Axons and Myelin Experimental Neurology. Aug, 2013 | Pubmed ID: 22569104 Sex-specific Differences in Retinal Nerve Fiber Layer Thinning After Acute Optic Neuritis Neurology. Oct, 2012 | Pubmed ID: 23077012 Will the Real Multiple Sclerosis Please Stand Up? Nature Reviews. Neuroscience. Jul, 2012 | Pubmed ID: 22714021 Copper-dependent Regulation of NMDA Receptors by Cellular Prion Protein: Implications for Neurodegenerative Disorders The Journal of Physiology. Mar, 2012 | Pubmed ID: 22310309 Aβ Neurotoxicity Depends on Interactions Between Copper Ions, Prion Protein, and N-methyl-D-aspartate Receptors Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22307640 The Axo-myelinic Synapse Trends in Neurosciences. Aug, 2011 | Pubmed ID: 21741098 Multiple Sclerosis: Autoimmune Disease or Autoimmune Reaction? The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Sep, 2010 | Pubmed ID: 21246931 Miniaturized Multimodal CARS Microscope Based on MEMS Scanning and a Single Laser Source Optics Express. Nov, 2010 | Pubmed ID: 21164724 Excitatory Glycine Responses of CNS Myelin Mediated by NR1/NR3 "NMDA" Receptor Subunits The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010 | Pubmed ID: 20739572 Mechanisms of Axonal Injury: Internodal Nanocomplexes and Calcium Deregulation Trends in Molecular Medicine. Apr, 2010 | Pubmed ID: 20207196 Degeneration Versus Autoimmunity in Multiple Sclerosis Annals of Neurology. Dec, 2009 | Pubmed ID: 20033985 Role of Prions in Neuroprotection and Neurodegeneration: a Mechanism Involving Glutamate Receptors? Prion. Oct-Dec, 2009 | Pubmed ID: 19684483 Gray Matter Pathology in (chronic) MS: Modern Views on an Early Observation Journal of the Neurological Sciences. Jul, 2009 | Pubmed ID: 19249061 Virtual Hypoxia and Chronic Necrosis of Demyelinated Axons in Multiple Sclerosis The Lancet. Neurology. Mar, 2009 | Pubmed ID: 19233038 Glutamate Receptors on Myelinated Spinal Cord Axons: I. GluR6 Kainate Receptors Annals of Neurology. Feb, 2009 | Pubmed ID: 19224535 Glutamate Receptors on Myelinated Spinal Cord Axons: II. AMPA and GluR5 Receptors Annals of Neurology. Feb, 2009 | Pubmed ID: 19224531 Effects of the Noradrenergic System in Rat White Matter Exposed to Oxygen-glucose Deprivation in Vitro The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2009 | Pubmed ID: 19211886 Coherent Anti-Stokes Raman Scattering Microscopy Using Photonic Crystal Fiber with Two Closely Lying Zero Dispersion Wavelengths Optics Express. Oct, 2007 | Pubmed ID: 19550675 White Matter NMDA Receptors: an Unexpected New Therapeutic Target? Trends in Pharmacological Sciences. Nov, 2007 | Pubmed ID: 17961731 Sodium Channel Blockers As Neuroprotectants in Neuroinflammatory Disease: a Double-edged Sword Annals of Neurology. Jul, 2007 | Pubmed ID: 17661358 Real-time Measurement of Free Ca2+ Changes in CNS Myelin by Two-photon Microscopy Nature Medicine. Jul, 2007 | Pubmed ID: 17603496 Sources of Axonal Calcium Loading During in Vitro Ischemia of Rat Dorsal Roots Muscle & Nerve. Apr, 2007 | Pubmed ID: 17206661 Complex Interplay Between Glutamate Receptors and Intracellular Ca2+ Stores During Ischaemia in Rat Spinal Cord White Matter The Journal of Physiology. Nov, 2006 | Pubmed ID: 16945971 Acute Anterior Circulation Stroke: Recanalization Using Clot Angioplasty The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. May, 2006 | Pubmed ID: 16736734 Spatiotemporal Distribution of Spectrin Breakdown Products Induced by Anoxia in Adult Rat Optic Nerve in Vitro Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2006 | Pubmed ID: 16163297 Na+-dependent Sources of Intra-axonal Ca2+ Release in Rat Optic Nerve During in Vitro Chemical Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2005 | Pubmed ID: 16251444 General Mechanisms of Axonal Damage and Its Prevention Journal of the Neurological Sciences. Jun, 2005 | Pubmed ID: 15899499 Functional Innervation in Tissue Engineered Models for in Vitro Study and Testing Purposes Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2004 | Pubmed ID: 15342958 Traumatic Axonal Injury Induces Proteolytic Cleavage of the Voltage-gated Sodium Channels Modulated by Tetrodotoxin and Protease Inhibitors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004 | Pubmed ID: 15140932 Axonal Degeneration in Multiple Sclerosis: is It Time for Neuroprotective Strategies? Annals of Neurology. May, 2004 | Pubmed ID: 15122698 Conversion of the Nikon C1 Confocal Laser-scanning Head for Multiphoton Excitation on an Upright Microscope Applied Optics. Mar, 2004 | Pubmed ID: 15046170 White Matter Injury Mechanisms Current Molecular Medicine. Mar, 2004 | Pubmed ID: 15032708 Nicotinic Acetylcholine Receptors in Mouse and Rat Optic Nerves Journal of Neurophysiology. Feb, 2004 | Pubmed ID: 14762152 Innervated Human Corneal Equivalents As in Vitro Models for Nerve-target Cell Interactions FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2004 | Pubmed ID: 14597567 Depolarization-induced Ca2+ Release in Ischemic Spinal Cord White Matter Involves L-type Ca2+ Channel Activation of Ryanodine Receptors Neuron. Sep, 2003 | Pubmed ID: 14527433 Aberrant Chloride Transport Contributes to Anoxic/ischemic White Matter Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2003 | Pubmed ID: 12736353 Calpain-dependent Neurofilament Breakdown in Anoxic and Ischemic Rat Central Axons Neuroscience Letters. Aug, 2002 | Pubmed ID: 12133577 An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time Starlyn L. M. Okada1, Nicole S. Stivers1, Peter K. Stys2, David P. Stirling1 1KY Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, 2Hotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary JoVE 52173 Neuroscience
An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time Starlyn L. M. Okada1, Nicole S. Stivers1, Peter K. Stys2, David P. Stirling1 1KY Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, 2Hotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary JoVE 52173 Neuroscience