Robert W. Sobol Department of Pharmacology & Chemical Biology University of Pittsburgh School of Medicine Biography Publications Institution JoVE Articles Robert W. Sobol has not added a biography. If you are Robert W. Sobol and would like to personalize this page please email our Author Liaison for assistance. Publications Identification and Characterization of Human Apurinic/apyrimidinic Endonuclease-1 Inhibitors Biochemistry. Jul, 2012 | Pubmed ID: 22788932 Chemistry & Biology. Mar, 2012 | Pubmed ID: 22444586 Current Molecular Pharmacology. Jan, 2012 | Pubmed ID: 22122465 XRCC1 and Base Excision Repair Balance in Response to Nitric Oxide DNA Repair. Dec, 2011 | Pubmed ID: 22041025 The Base Excision Repair Pathway is Required for Efficient Lentivirus Integration PloS One. 2011 | Pubmed ID: 21448280 Following Cytochrome C Release, Autophagy is Inhibited During Chemotherapy-induced Apoptosis by Caspase 8-mediated Cleavage of Beclin 1 Cancer Research. May, 2011 | Pubmed ID: 21444671 Cancer. Apr, 2011 | Pubmed ID: 21425146 Cancer Research. Mar, 2011 | Pubmed ID: 21406402 Neuro-oncology. May, 2011 | Pubmed ID: 21377995 The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21357694 BMC Medical Genomics. 2011 | Pubmed ID: 21269491 Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. Jan, 2011 | Pubmed ID: 20725730 Antioxidants & Redox Signaling. Jun, 2011 | Pubmed ID: 20649466 Pediatric Blood & Cancer. Dec, 2010 | Pubmed ID: 20589656 Carcinogenesis. May, 2010 | Pubmed ID: 20197299 Mutation Research. Apr, 2010 | Pubmed ID: 20096707 Molecular Cancer Research : MCR. Jan, 2010 | Pubmed ID: 20068071 DNA Polymerase Beta-dependent Long Patch Base Excision Repair in Living Cells DNA Repair. Feb, 2010 | Pubmed ID: 20006562 Carcinogenesis. Dec, 2009 | Pubmed ID: 19864471 BMC Cancer. 2009 | Pubmed ID: 19807915 Gastrointestinal Hyperplasia with Altered Expression of DNA Polymerase Beta PloS One. 2009 | Pubmed ID: 19654874 Proceedings of the National Academy of Sciences of the United States of America. Jun, 2009 | Pubmed ID: 19520829 Mutagenesis is Elevated in Male Germ Cells Obtained from DNA Polymerase-beta Heterozygous Mice Biology of Reproduction. Nov, 2008 | Pubmed ID: 18650495 Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18614692 Molecular Pharmacology. Aug, 2008 | Pubmed ID: 18477668 Molecular Cell. Feb, 2008 | Pubmed ID: 18313379 DNA Repair. Jun, 2007 | Pubmed ID: 17337257 Cancer Research. Mar, 2007 | Pubmed ID: 17332367 DNA Repair. Jan, 2007 | Pubmed ID: 16979388 The American Journal of Pathology. Nov, 2006 | Pubmed ID: 17071602 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2006 | Pubmed ID: 16849758 Cancer Research. Jul, 2005 | Pubmed ID: 16024643 Increased Postischemic Brain Injury in Mice Deficient in Uracil-DNA Glycosylase The Journal of Clinical Investigation. Jun, 2004 | Pubmed ID: 15199406 Base Excision Repair Deficiency Caused by Polymerase Beta Haploinsufficiency: Accelerated DNA Damage and Increased Mutational Response to Carcinogens Cancer Research. Sep, 2003 | Pubmed ID: 14522902 Base Excision Repair Intermediates Induce P53-independent Cytotoxic and Genotoxic Responses The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12882965 Regulated Over-expression of DNA Polymerase Beta Mediates Early Onset Cataract in Mice DNA Repair. May, 2003 | Pubmed ID: 12713817 Involvement of DNA Polymerase Beta in Protection Against the Cytotoxicity of Oxidative DNA Damage DNA Repair. Apr, 2002 | Pubmed ID: 12509250 Binary System for Selective Photoaffinity Labeling of Base Excision Repair DNA Polymerases Nucleic Acids Research. Jul, 2002 | Pubmed ID: 12136121 Mutations Associated with Base Excision Repair Deficiency and Methylation-induced Genotoxic Stress Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 11983862 Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons David Svilar1,2, Conchita Vens3, Robert W. Sobol1,2,4 1Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, 2Hillman Cancer Center, University of Pittsburgh Cancer Institute, 3Department of Experimental Therapy, The Netherlands Cancer Institute, 4Department of Human Genetics, University of Pittsburgh School of Public Health JoVE 4168 Biology
Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons David Svilar1,2, Conchita Vens3, Robert W. Sobol1,2,4 1Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, 2Hillman Cancer Center, University of Pittsburgh Cancer Institute, 3Department of Experimental Therapy, The Netherlands Cancer Institute, 4Department of Human Genetics, University of Pittsburgh School of Public Health JoVE 4168 Biology