Robin J. M. Franklin Wellcome Trust-MRC Cambridge Stem Cell Institute University of Cambridge Biography Publications Institution JoVE Articles Robin J. M. Franklin has not added a biography. If you are Robin J. M. Franklin and would like to personalize this page please email our Author Liaison for assistance. Publications Remyelination in the Central Nervous System Cold Spring Harbor Perspectives in Biology. Feb, 2024 | Pubmed ID: 38316552 Targeted Evolution of Adeno-associated Virus Capsids for Systemic Transgene Delivery to Microglia and Tissue-resident Macrophages Proceedings of the National Academy of Sciences of the United States of America. Aug, 2023 | Pubmed ID: 37603759 SARM1 Detection in Myelinating Glia: / is Dispensable for PNS and CNS Myelination in Zebrafish and Mice Frontiers in Cellular Neuroscience. 2023 | Pubmed ID: 37091921 Cell-free DNA-based Liquid Biopsies in Neurology Brain : a Journal of Neurology. May, 2023 | Pubmed ID: 36408894 Ageing and Multiple Sclerosis The Lancet. Neurology. Jan, 2023 | Pubmed ID: 36216015 Axonal Response of Mitochondria to Demyelination and Complex IV Activity Within Demyelinated Axons in Experimental Models of Multiple Sclerosis Neuropathology and Applied Neurobiology. Feb, 2023 | Pubmed ID: 36181265 CNS Remyelination and Inflammation: From Basic Mechanisms to Therapeutic Opportunities Neuron. Nov, 2022 | Pubmed ID: 36228613 Remyelination in Humans Due to a Retinoid-X Receptor Agonist is Age-dependent Annals of Clinical and Translational Neurology. Jul, 2022 | Pubmed ID: 35587315 Dissection of Artifactual and Confounding Glial Signatures by Single-cell Sequencing of Mouse and Human Brain Nature Neuroscience. Mar, 2022 | Pubmed ID: 35260865 Myc Determines the Functional Age State of Oligodendrocyte Progenitor Cells Nature Aging. Sep, 2021 | Pubmed ID: 37117631 Safety and Efficacy of Bexarotene in Patients with Relapsing-remitting Multiple Sclerosis (CCMR One): a Randomised, Double-blind, Placebo-controlled, Parallel-group, Phase 2a Study The Lancet. Neurology. Sep, 2021 | Pubmed ID: 34418398 Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity? Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 34381334 Nutritional Regulation of Oligodendrocyte Differentiation Regulates Perineuronal Net Remodeling in the Median Eminence Cell Reports. Jul, 2021 | Pubmed ID: 34260928 A Map of Transcriptional Heterogeneity and Regulatory Variation in Human Microglia Nature Genetics. Jun, 2021 | Pubmed ID: 34083789 Neuroprotective Effects of Sonic Hedgehog Agonist SAG in a Rat Model of Neonatal Stroke Pediatric Research. Dec, 2021 | Pubmed ID: 33654279 Author Correction: Genome-wide Meta-analysis, Fine-mapping and Integrative Prioritization Implicate New Alzheimer's Disease Risk Genes Nature Genetics. Apr, 2021 | Pubmed ID: 33637963 Genome-wide Meta-analysis, Fine-mapping and Integrative Prioritization Implicate New Alzheimer's Disease Risk Genes Nature Genetics. Mar, 2021 | Pubmed ID: 33589840 Schwann Cell Remyelination of the Central Nervous System: Why Does It Happen and What Are the Benefits? Open Biology. Jan, 2021 | Pubmed ID: 33497588 Revisiting Remyelination: Towards a Consensus on the Regeneration of CNS Myelin Seminars in Cell & Developmental Biology. Aug, 2021 | Pubmed ID: 33082115 The Role of Astrocytes in Remyelination Trends in Neurosciences. Aug, 2020 | Pubmed ID: 32620289 Enhanced Axonal Response of Mitochondria to Demyelination Offers Neuroprotection: Implications for Multiple Sclerosis Acta Neuropathologica. Aug, 2020 | Pubmed ID: 32572598 Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing Molecular & Cellular Proteomics : MCP. Aug, 2020 | Pubmed ID: 32434922 Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis Cell Stem Cell. May, 2020 | Pubmed ID: 32386552 Correction To: Niacin-mediated Rejuvenation of Macrophage/microglia Enhances Remyelination of the Aging Central Nervous System Acta Neuropathologica. May, 2020 | Pubmed ID: 32211925 Niacin-mediated Rejuvenation of Macrophage/microglia Enhances Remyelination of the Aging Central Nervous System Acta Neuropathologica. May, 2020 | Pubmed ID: 32030468 The Fatty Acid Binding Protein FABP7 is Required for Optimal Oligodendrocyte Differentiation During Myelination but Not During Remyelination Glia. Jul, 2020 | Pubmed ID: 32017258 Astrocyte Unfolded Protein Response Induces a Specific Reactivity State That Causes Non-Cell-Autonomous Neuronal Degeneration Neuron. Mar, 2020 | Pubmed ID: 31924446 The Microbiota Regulates Murine Inflammatory Responses to Toxin-induced CNS Demyelination but Has Minimal Impact on Remyelination Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31740610 Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation Cell Stem Cell. Oct, 2019 | Pubmed ID: 31585094 Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells Cell Stem Cell. Oct, 2019 | Pubmed ID: 31585093 Author Correction: Niche Stiffness Underlies the Ageing of Central Nervous System Progenitor Cells Nature. Sep, 2019 | Pubmed ID: 31462780 Niche Stiffness Underlies the Ageing of Central Nervous System Progenitor Cells Nature. Sep, 2019 | Pubmed ID: 31413369 Neuronal Vulnerability and Multilineage Diversity in Multiple Sclerosis Nature. Sep, 2019 | Pubmed ID: 31316211 Aging Restricts the Ability of Mesenchymal Stem Cells to Promote the Generation of Oligodendrocytes During Remyelination Glia. Aug, 2019 | Pubmed ID: 31038798 Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells Frontiers in Cellular Neuroscience. 2019 | Pubmed ID: 30971893 Diversity in the Oligodendrocyte Lineage: Plasticity or Heterogeneity? Glia. Oct, 2019 | Pubmed ID: 30968471 SUMOylation Promotes Survival and Integration of Neural Stem Cell Grafts in Ischemic Stroke EBioMedicine. Apr, 2019 | Pubmed ID: 30905846 Transforming Growth Factor-beta Renders Ageing Microglia Inhibitory to Oligodendrocyte Generation by CNS Progenitors Glia. Jul, 2019 | Pubmed ID: 30861188 Toxin-Based Models to Investigate Demyelination and Remyelination Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30820910 Single-Cell RNA Sequencing of Microglia Throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes Immunity. Jan, 2019 | Pubmed ID: 30471926 A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2018 | Pubmed ID: 30228229 Clemastine Rescues Myelination Defects and Promotes Functional Recovery in Hypoxic Brain Injury Brain : a Journal of Neurology. 01, 2018 | Pubmed ID: 29244098 Regenerating CNS Myelin - from Mechanisms to Experimental Medicines Nature Reviews. Neuroscience. Nov, 2017 | Pubmed ID: 29142295 Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation During CNS Remyelination Cell Reports. Aug, 2017 | Pubmed ID: 28834740 Do Not Adjust Your Mind: The Fault Is in Your Glia Cell Stem Cell. Aug, 2017 | Pubmed ID: 28777939 Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease Progress in Brain Research. 2017 | Pubmed ID: 28554395 Erratum To: Antibody-mediated Neutralization of Myelin-associated EphrinB3 Accelerates CNS Remyelination Acta Neuropathologica. Jul, 2017 | Pubmed ID: 28484846 Efficient Remyelination Requires DNA Methylation ENeuro. 2017 | Pubmed ID: 28451635 Regulatory T Cells Promote Myelin Regeneration in the Central Nervous System Nature Neuroscience. May, 2017 | Pubmed ID: 28288125 Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice Stem Cell Reports. Mar, 2017 | Pubmed ID: 28196689 Unexpected Central Role of the Androgen Receptor in the Spontaneous Regeneration of Myelin Proceedings of the National Academy of Sciences of the United States of America. Dec, 2016 | Pubmed ID: 27930320 MRI Measurements of Reporter-mediated Increases in Transmembrane Water Exchange Enable Detection of a Gene Reporter Nature Biotechnology. Dec, 2016 | Pubmed ID: 27918546 Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) Via β1 Integrin International Journal of Molecular Sciences. Nov, 2016 | Pubmed ID: 27879672 Axonal Plasticity Underpins the Functional Recovery Following Surgical Decompression in a Rat Model of Cervical Spondylotic Myelopathy Acta Neuropathologica Communications. Aug, 2016 | Pubmed ID: 27552807 CNS Remyelination and the Innate Immune System Frontiers in Cell and Developmental Biology. 2016 | Pubmed ID: 27200350 Erratum To: Antibody-mediated Neutralization of Myelin-associated EphrinB3 Accelerates CNS Remyelination Acta Neuropathologica. Jul, 2016 | Pubmed ID: 27161252 Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline Cell Reports. Apr, 2016 | Pubmed ID: 27149850 Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage Cell Reports. Apr, 2016 | Pubmed ID: 27149841 Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination Following Toxin-Induced Spinal Cord Demyelination The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26773350 Antibody-mediated Neutralization of Myelin-associated EphrinB3 Accelerates CNS Remyelination Acta Neuropathologica. Feb, 2016 | Pubmed ID: 26687980 Neuronal Expression of Pathological Tau Accelerates Oligodendrocyte Progenitor Cell Differentiation Glia. Mar, 2016 | Pubmed ID: 26576485 Pioglitazone Regulates Myelin Phagocytosis and Multiple Sclerosis Monocytes Annals of Clinical and Translational Neurology. Dec, 2015 | Pubmed ID: 26734659 Vitamin D Receptor-retinoid X Receptor Heterodimer Signaling Regulates Oligodendrocyte Progenitor Cell Differentiation The Journal of Cell Biology. Dec, 2015 | Pubmed ID: 26644513 Retinoid X Receptor Activation Reverses Age-related Deficiencies in Myelin Debris Phagocytosis and Remyelination Brain : a Journal of Neurology. Dec, 2015 | Pubmed ID: 26463675 Neuronal Activity Regulates Remyelination Via Glutamate Signalling to Oligodendrocyte Progenitors Nature Communications. Oct, 2015 | Pubmed ID: 26439639 Discovery of a Novel Neuroprotectant, BHDPC, That Protects Against MPP+/MPTP-induced Neuronal Death in Multiple Experimental Models Free Radical Biology & Medicine. Dec, 2015 | Pubmed ID: 26415025 Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells Following CNS Demyelination and Primes Them for Differentiation During Remyelination The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2015 | Pubmed ID: 26290228 Astrocyte Activation Via Stat3 Signaling Determines the Balance of Oligodendrocyte Versus Schwann Cell Remyelination The American Journal of Pathology. Sep, 2015 | Pubmed ID: 26193667 Regenerative Medicines for Remyelination: From Aspiration to Reality Cell Stem Cell. Jun, 2015 | Pubmed ID: 26046755 Glia Disease and Repair-Remyelination Cold Spring Harbor Perspectives in Biology. May, 2015 | Pubmed ID: 25986556 Fibroblast Growth Factor Signaling in Oligodendrocyte-lineage Cells Facilitates Recovery of Chronically Demyelinated Lesions but is Redundant in Acute Lesions Glia. Oct, 2015 | Pubmed ID: 25913734 The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis Following Spinal Cord Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2015 | Pubmed ID: 25904802 Lesion-induced Accumulation of Platelets Promotes Survival of Adult Neural Stem / Progenitor Cells Experimental Neurology. Jul, 2015 | Pubmed ID: 25819103 Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2015 | Pubmed ID: 25568099 The EIIIA Domain from Astrocyte-derived Fibronectin Mediates Proliferation of Oligodendrocyte Progenitor Cells Following CNS Demyelination Glia. Feb, 2015 | Pubmed ID: 25156142 Astrocyte Response to Motor Neuron Injury Promotes Structural Synaptic Plasticity Via STAT3-regulated TSP-1 Expression Nature Communications. Jul, 2014 | Pubmed ID: 25014177 Micropillar Arrays As a High-throughput Screening Platform for Therapeutics in Multiple Sclerosis Nature Medicine. Aug, 2014 | Pubmed ID: 24997607 Special Issue on Stem Cells: "the End of the Beginning" Experimental Neurology. Oct, 2014 | Pubmed ID: 24950181 Multiple Sclerosis Genetics The Lancet. Neurology. Jul, 2014 | Pubmed ID: 24852507 Auxetic Nuclei in Embryonic Stem Cells Exiting Pluripotency Nature Materials. Jun, 2014 | Pubmed ID: 24747782 The Translational Biology of Remyelination: Past, Present, and Future Glia. Nov, 2014 | Pubmed ID: 24446279 Cell Therapy for Spinal Cord Injuries: What is Really Going On? The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Dec, 2014 | Pubmed ID: 24415275 Neuregulin and BDNF Induce a Switch to NMDA Receptor-dependent Myelination by Oligodendrocytes PLoS Biology. Dec, 2013 | Pubmed ID: 24391468 Inhibition of Phosphodiesterase-4 Promotes Oligodendrocyte Precursor Cell Differentiation and Enhances CNS Remyelination EMBO Molecular Medicine. Dec, 2013 | Pubmed ID: 24293318 M2 Microglia and Macrophages Drive Oligodendrocyte Differentiation During CNS Remyelination Nature Neuroscience. Sep, 2013 | Pubmed ID: 23872599 The Late Response of Rat Subependymal Zone Stem and Progenitor Cells to Stroke is Restricted to Directly Affected Areas of Their Niche Experimental Neurology. Oct, 2013 | Pubmed ID: 23830949 Peroxisome Proliferator-activated Receptor Gamma-coactivator-1 Alpha Coordinates Sphingolipid Metabolism, Lipid Raft Composition and Myelin Protein Synthesis The European Journal of Neuroscience. Sep, 2013 | Pubmed ID: 23763823 Ageing Stem and Progenitor Cells: Implications for Rejuvenation of the Central Nervous System Development (Cambridge, England). Jun, 2013 | Pubmed ID: 23715549 Neural Precursor Cells Cultured at Physiologically Relevant Oxygen Tensions Have a Survival Advantage Following Transplantation Stem Cells Translational Medicine. Jun, 2013 | Pubmed ID: 23677643 Myokymia and Neuromyotonia in Veterinary Medicine: a Comparison with Peripheral Nerve Hyperexcitability Syndrome in Humans Veterinary Journal (London, England : 1997). Aug, 2013 | Pubmed ID: 23583699 Identification of Endothelin 2 As an Inflammatory Factor That Promotes Central Nervous System Remyelination Brain : a Journal of Neurology. Apr, 2013 | Pubmed ID: 23518706 Do Your Glial Cells Make You Clever? Cell Stem Cell. Mar, 2013 | Pubmed ID: 23472865 Embryonic-derived Olfactory Ensheathing Cells Remyelinate Focal Areas of Spinal Cord Demyelination More Efficiently Than Neonatal or Adult-derived Cells Cell Transplantation. 2013 | Pubmed ID: 23031825 Current Status of Myelin Replacement Therapies in Multiple Sclerosis Progress in Brain Research. 2012 | Pubmed ID: 23186717 Autologous Olfactory Mucosal Cell Transplants in Clinical Spinal Cord Injury: a Randomized Double-blinded Trial in a Canine Translational Model Brain : a Journal of Neurology. Nov, 2012 | Pubmed ID: 23169917 Neuroprotection and Repair in Multiple Sclerosis Nature Reviews. Neurology. Nov, 2012 | Pubmed ID: 23026979 Accelerated Axonal Loss Following Acute CNS Demyelination in Mice Lacking Protein Tyrosine Phosphatase Receptor Type Z The American Journal of Pathology. Nov, 2012 | Pubmed ID: 22940073 Mechanical Environment Modulates Biological Properties of Oligodendrocyte Progenitor Cells Stem Cells and Development. Nov, 2012 | Pubmed ID: 22646081 Rejuvenation of Regeneration in the Aging Central Nervous System Cell Stem Cell. Jan, 2012 | Pubmed ID: 22226359 轴突产物抑制剂 NOGO-A 建立了空间隔离和少突胶质细胞髓鞘的程度。 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22160722 Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2011 | Pubmed ID: 21904791 Axin2 As Regulatory and Therapeutic Target in Newborn Brain Injury and Remyelination Nature Neuroscience. Jun, 2011 | Pubmed ID: 21706018 Increased Mitochondrial Content in Remyelinated Axons: Implications for Multiple Sclerosis Brain : a Journal of Neurology. Jul, 2011 | Pubmed ID: 21705418 Regenerative Medicine in Multiple Sclerosis: Identifying Pharmacological Targets of Adult Neural Stem Cell Differentiation Neurochemistry International. Sep, 2011 | Pubmed ID: 21300122 Genetically Induced Adult Oligodendrocyte Cell Death is Associated with Poor Myelin Clearance, Reduced Remyelination, and Axonal Damage The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2011 | Pubmed ID: 21248132 Retinoid X Receptor Gamma Signaling Accelerates CNS Remyelination Nature Neuroscience. Jan, 2011 | Pubmed ID: 21131950 Oligodendrocyte PTEN is Required for Myelin and Axonal Integrity, Not Remyelination Annals of Neurology. Nov, 2010 | Pubmed ID: 20853437 Mechanical Difference Between White and Gray Matter in the Rat Cerebellum Measured by Scanning Force Microscopy Journal of Biomechanics. Nov, 2010 | Pubmed ID: 20656292 CNS-resident Glial Progenitor/stem Cells Produce Schwann Cells As Well As Oligodendrocytes During Repair of CNS Demyelination Cell Stem Cell. Jun, 2010 | Pubmed ID: 20569695 Drug Reprofiling Using Zebrafish Identifies Novel Compounds with Potential Pro-myelination Effects Neuropharmacology. Sep, 2010 | Pubmed ID: 20450924 FGF but Not EGF Induces Phosphorylation of the CAMP Response Element Binding Protein in Olfactory Mucosa-derived Cell Cultures Experimental Cell Research. May, 2010 | Pubmed ID: 20211167 Temporal Dynamics of Myelination in the Zebrafish Spinal Cord Glia. May, 2010 | Pubmed ID: 20140960 Remyelination - An Effective Means of Neuroprotection Hormones and Behavior. Jan, 2010 | Pubmed ID: 19538961 Up-regulation of Oligodendrocyte Precursor Cell AlphaV Integrin and Its Extracellular Ligands During Central Nervous System Remyelination Journal of Neuroscience Research. Nov, 2009 | Pubmed ID: 19739252 时异常经典 Wnt 信号通路的抑制及时髓鞘和哺乳动物中枢神经系统髓鞘再生。 Genes & Development. Jul, 2009 | Pubmed ID: 19515974 移植少突胶质前体细胞减少神经变性的青光眼模型中。 Investigative Ophthalmology & Visual Science. Sep, 2009 | Pubmed ID: 19357352 Myelin-mediated Inhibition of Oligodendrocyte Precursor Differentiation Can Be Overcome by Pharmacological Modulation of Fyn-RhoA and Protein Kinase C Signalling Brain : a Journal of Neurology. Feb, 2009 | Pubmed ID: 19208690 Age-dependent Epigenetic Control of Differentiation Inhibitors is Critical for Remyelination Efficiency Nature Neuroscience. Sep, 2008 | Pubmed ID: 19160500 Zebrafish Myelination: a Transparent Model for Remyelination? Disease Models & Mechanisms. 2008 | Pubmed ID: 19093028 Quantification of Deficits in Lateral Paw Positioning After Spinal Cord Injury in Dogs BMC Veterinary Research. Nov, 2008 | Pubmed ID: 19032742 Remyelination in the CNS: from Biology to Therapy Nature Reviews. Neuroscience. Nov, 2008 | Pubmed ID: 18931697 显示区域变化中胶质细胞增生、 髓鞘再生、 弥漫性轴索和神经元丢失的次要多发性硬化的实验模型。 Journal of Neuroimmunology. Sep, 2008 | Pubmed ID: 18672298 Osteopontin is Extensively Expressed by Macrophages Following CNS Demyelination but Has a Redundant Role in Remyelination Neurobiology of Disease. Aug, 2008 | Pubmed ID: 18539470 Taking Ageing into Account in Remyelination-based Therapies for Multiple Sclerosis Journal of the Neurological Sciences. Nov, 2008 | Pubmed ID: 18539300 Serum-free Medium Provides a Clinically Relevant Method to Increase Olfactory Ensheathing Cell Numbers in Olfactory Mucosa Cell Culture Cell Transplantation. 2008 | Pubmed ID: 18351018 The Biology of CNS Remyelination: the Key to Therapeutic Advances Journal of Neurology. Mar, 2008 | Pubmed ID: 18317673 Promoting Remyelination in Multiple Sclerosis by Endogenous Adult Neural Stem/precursor Cells: Defining Cellular Targets Journal of the Neurological Sciences. Feb, 2008 | Pubmed ID: 17570402 Myelin Repair: the Role of Stem and Precursor Cells in Multiple Sclerosis Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jan, 2008 | Pubmed ID: 17282989 Serum-Free Medium Provides a Clinically Relevant Method to Increase Olfactory Ensheathing Cell Numbers in Olfactory Mucosa Cell Culture Cell Transplantation. Nov, 2007 | Pubmed ID: 28866922 Contrasting Effects of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Mouse Neonatal Olfactory Mucosa Cells The European Journal of Neuroscience. Dec, 2007 | Pubmed ID: 18088275 Development of a Universal Measure of Quadrupedal Forelimb-hindlimb Coordination Using Digital Motion Capture and Computerised Analysis BMC Neuroscience. Sep, 2007 | Pubmed ID: 17877823 Essential and Distinct Roles for Cdc42 and Rac1 in the Regulation of Schwann Cell Biology During Peripheral Nervous System Development The Journal of Cell Biology. Jun, 2007 | Pubmed ID: 17576798 Myelin Regeneration in Demyelinating Disorders: New Developments in Biology and Clinical Pathology Current Opinion in Neurology. Jun, 2007 | Pubmed ID: 17495623 Mutations in Genes Causing Human Familial Isolated Hyperparathyroidism Do Not Account for Hyperparathyroidism in Keeshond Dogs Veterinary Journal (London, England : 1997). Nov, 2007 | Pubmed ID: 17158076 Calponin is Expressed by Fibroblasts and Meningeal Cells but Not Olfactory Ensheathing Cells in the Adult Peripheral Olfactory System Glia. Jan, 2007 | Pubmed ID: 17078028 Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2006 | Pubmed ID: 17021167 Inflammation Stimulates Myelination by Transplanted Oligodendrocyte Precursor Cells Glia. Sep, 2006 | Pubmed ID: 16856149 Females Remyelinate More Efficiently Than Males Following Demyelination in the Aged but Not Young Adult CNS Experimental Neurology. Nov, 2006 | Pubmed ID: 16797535 Comparison of Cell Populations Derived from Canine Olfactory Bulb and Olfactory Mucosal Cultures American Journal of Veterinary Research. Jun, 2006 | Pubmed ID: 16740101 Magnetic Resonance Imaging of Functional Schwann Cell Transplants Labelled with Magnetic Microspheres NeuroImage. May, 2006 | Pubmed ID: 16442816 Corticosteroids Delay Remyelination of Experimental Demyelination in the Rodent Central Nervous System Journal of Neuroscience Research. Mar, 2006 | Pubmed ID: 16429447 Oligodendrocyte Progenitor Cell (OPC) Transplantation is Unlikely to Offer a Means of Preventing X-irradiation Induced Damage in the CNS Experimental Neurology. Mar, 2006 | Pubmed ID: 16410004 Myelin Impairs CNS Remyelination by Inhibiting Oligodendrocyte Precursor Cell Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16399703 Differences in the Early Inflammatory Responses to Toxin-induced Demyelination Are Associated with the Age-related Decline in CNS Remyelination Neurobiology of Aging. Sep, 2006 | Pubmed ID: 16051398 Autologous Olfactory Glial Cell Transplantation is Reliable and Safe in Naturally Occurring Canine Spinal Cord Injury Journal of Neurotrauma. Nov, 2005 | Pubmed ID: 16305316 Stem Cells, Progenitors and Myelin Repair Journal of Anatomy. Sep, 2005 | Pubmed ID: 16185249 Mechanisms of CNS Remyelination--the Key to Therapeutic Advances Journal of the Neurological Sciences. Jun, 2005 | Pubmed ID: 15949498 Macrophage-depletion Induced Impairment of Experimental CNS Remyelination is Associated with a Reduced Oligodendrocyte Progenitor Cell Response and Altered Growth Factor Expression Neurobiology of Disease. Feb, 2005 | Pubmed ID: 15649707 Minocycline-mediated Inhibition of Microglia Activation Impairs Oligodendrocyte Progenitor Cell Responses and Remyelination in a Non-immune Model of Demyelination Journal of Neuroimmunology. Jan, 2005 | Pubmed ID: 15589038 Superparamagnetic Iron Oxide-labeled Schwann Cells and Olfactory Ensheathing Cells Can Be Traced in Vivo by Magnetic Resonance Imaging and Retain Functional Properties After Transplantation into the CNS The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2004 | Pubmed ID: 15525765 Increased Expression of Nkx2.2 and Olig2 Identifies Reactive Oligodendrocyte Progenitor Cells Responding to Demyelination in the Adult CNS Molecular and Cellular Neurosciences. Nov, 2004 | Pubmed ID: 15519240 Notch1 and Jagged1 Are Expressed After CNS Demyelination, but Are Not a Major Rate-determining Factor During Remyelination Brain : a Journal of Neurology. Sep, 2004 | Pubmed ID: 15289265 神经科学。髓鞘的奥秘打开。 Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15118149 CNS Axons Retain Their Competence for Myelination Throughout Life Glia. Feb, 2004 | Pubmed ID: 14730704 Olfactory Ensheathing Cells Induce Less Host Astrocyte Response and Chondroitin Sulphate Proteoglycan Expression Than Schwann Cells Following Transplantation into Adult CNS White Matter Experimental Neurology. Nov, 2003 | Pubmed ID: 14637095 Increasing Local Levels of Neuregulin (glial Growth Factor-2) by Direct Infusion into Areas of Demyelination Does Not Alter Remyelination in the Rat CNS The European Journal of Neuroscience. Oct, 2003 | Pubmed ID: 14622186 Quantifying the Early Stages of Remyelination Following Cuprizone-induced Demyelination Brain Pathology (Zurich, Switzerland). Jul, 2003 | Pubmed ID: 12946022 Impaired Remyelination and Depletion of Oligodendrocyte Progenitors Does Not Occur Following Repeated Episodes of Focal Demyelination in the Rat Central Nervous System Brain : a Journal of Neurology. Jun, 2003 | Pubmed ID: 12764059 Remyelination by Transplanted Olfactory Ensheathing Cells Anatomical Record. Part B, New Anatomist. Mar, 2003 | Pubmed ID: 12619088 Lentiviral Vectors for Gene Delivery to Normal and Demyelinated White Matter Glia. Apr, 2003 | Pubmed ID: 12594737 Meningeal Cells Enhance Limited CNS Remyelination by Transplanted Olfactory Ensheathing Cells Brain : a Journal of Neurology. Mar, 2003 | Pubmed ID: 12566281 Transplant Mediated Repair of the Central Nervous System: an Imminent Solution? Current Opinion in Neurology. Dec, 2002 | Pubmed ID: 12447108 Expression of the POU-domain Transcription Factors SCIP/Oct-6 and Brn-2 is Associated with Schwann Cell but Not Oligodendrocyte Remyelination of the CNS Molecular and Cellular Neurosciences. Aug, 2002 | Pubmed ID: 12213447 Why Does Remyelination Fail in Multiple Sclerosis? Nature Reviews. Neuroscience. Sep, 2002 | Pubmed ID: 12209119 Remyelination of the Demyelinated CNS: the Case for and Against Transplantation of Central, Peripheral and Olfactory Glia Brain Research Bulletin. Apr, 2002 | Pubmed ID: 12031280 Ageing and CNS Remyelination Neuroreport. May, 2002 | Pubmed ID: 12004191 The Age-related Decrease in CNS Remyelination Efficiency is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2002 | Pubmed ID: 11923409 Recognition and Diagnosis of Lysosomal Storage Diseases in the Cat and Dog Journal of Veterinary Internal Medicine. 2002 | Pubmed ID: 11899921 What Roles Do Growth Factors Play in CNS Remyelination? Progress in Brain Research. 2001 | Pubmed ID: 11544987 Transplanting Oligodendrocyte Progenitors into the Adult CNS Journal of Anatomy. Jan, 1997 | Pubmed ID: 9034879 Collecting Neural Stem and Progenitor Cells from Live Animals Using a Novel Brain Milking Protocol (Video) | JoVE Dimitrios Dimitrakopoulos1, Chrisitna Dimitriou1, Freyja McClenahan2, Robin J. M. Franklin2,3, Ilias Kazanis1 1Laboratory of Developmental Biology, Department of Biology, University of Patras, 2Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, 3Altos Labs, Cambridge Institute of Science JoVE 65308 Neuroscience
Collecting Neural Stem and Progenitor Cells from Live Animals Using a Novel Brain Milking Protocol (Video) | JoVE Dimitrios Dimitrakopoulos1, Chrisitna Dimitriou1, Freyja McClenahan2, Robin J. M. Franklin2,3, Ilias Kazanis1 1Laboratory of Developmental Biology, Department of Biology, University of Patras, 2Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, 3Altos Labs, Cambridge Institute of Science JoVE 65308 Neuroscience