Roger S. Chung Department of Biomedical Sciences, Faculty of Medicine and Health Sciences Macquarie University Biography Publications Institution JoVE Articles Roger S. Chung has not added a biography. If you are Roger S. Chung and would like to personalize this page please email our Author Liaison for assistance. Publications Ultrastructural Mapping of the Zebrafish Gastrointestinal System As a Basis for Experimental Drug Studies BioMed Research International. 2016 | Pubmed ID: 27340669 CCNF Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Nature Communications. Apr, 2016 | Pubmed ID: 27080313 Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26778958 The Established and Emerging Roles of Astrocytes and Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26578880 Editorial: The Molecular Pathology of Cognitive Decline: Focus on Metals Frontiers in Aging Neuroscience. 2015 | Pubmed ID: 26136683 Microglia and Motor Neurons During Disease Progression in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis: Changes in Arginase1 and Inducible Nitric Oxide Synthase Journal of Neuroinflammation. Mar, 2014 | Pubmed ID: 24655927 Distribution of Exogenous Metallothionein Following Intraperitoneal and Intramuscular Injection of Metallothionein-deficient Mice Histology and Histopathology. 11, 2012 | Pubmed ID: 23018245 Redox-active Cu(II)-Aβ Causes Substantial Changes in Axonal Integrity in Cultured Cortical Neurons in an Oxidative-stress Dependent Manner Experimental Neurology. Oct, 2012 | Pubmed ID: 22691462 Metallothionein (MT) -I and MT-II Expression Are Induced and Cause Zinc Sequestration in the Liver After Brain Injury PloS One. 2012 | Pubmed ID: 22363575 Des Modèles De Rongeurs Récentes Pour La Maladie D'Alzheimer: Implications Cliniques Et De Recherche De Base Journal of Neural Transmission (Vienna, Austria : 1996). Feb, 2012 | Pubmed ID: 22086139 Metallothionein Promotes Regenerative Axonal Sprouting of Dorsal Root Ganglion Neurons After Physical Axotomy Cellular and Molecular Life Sciences : CMLS. Mar, 2012 | Pubmed ID: 21833580 Transcriptional Insights on the Regenerative Mechanics of Axotomized Neurons in Vitro Journal of Cellular and Molecular Medicine. Apr, 2012 | Pubmed ID: 21711447 Increased Circulating Leukocyte Numbers and Altered Macrophage Phenotype Correlate with the Altered Immune Response to Brain Injury in Metallothionein (MT)-I/II Null Mutant Mice Journal of Neuroinflammation. Dec, 2011 | Pubmed ID: 22152221 Neuroprotection and Regeneration by Extracellular Metallothionein Via Lipoprotein-receptor-related Proteins Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Oct, 2011 | Pubmed ID: 21779915 Tg2576 Cortical Neurons That Express Human Ab Are Susceptible to Extracellular Aβ-induced, K+ Efflux Dependent Neurodegeneration PloS One. Apr, 2011 | Pubmed ID: 21556141 Olfactory Ensheathing Cells Moderate Nuclear Factor KappaB Translocation in Astrocytes Molecular and Cellular Neurosciences. Jan, 2011 | Pubmed ID: 20840869 The Native Copper- and Zinc-binding Protein Metallothionein Blocks Copper-mediated Abeta Aggregation and Toxicity in Rat Cortical Neurons PloS One. Aug, 2010 | Pubmed ID: 20711450 Prolonged Abeta Treatment Leads to Impairment in the Ability of Primary Cortical Neurons to Maintain K+ and Ca2+ Homeostasis Molecular Neurodegeneration. Aug, 2010 | Pubmed ID: 20704753 Neuronal Growth-inhibitory Factor (metallothionein-3): Evaluation of the Biological Function of Growth-inhibitory Factor in the Injured and Neurodegenerative Brain The FEBS Journal. Jul, 2010 | Pubmed ID: 20561053 The Two Faces of Metallothionein in Carcinogenesis: Photoprotection Against UVR-induced Cancer and Promotion of Tumour Survival Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Apr, 2010 | Pubmed ID: 20354655 Zn(II)- and Cu(II)-induced Non-fibrillar Aggregates of Amyloid-beta (1-42) Peptide Are Transformed to Amyloid Fibrils, Both Spontaneously and Under the Influence of Metal Chelators Journal of Neurochemistry. Sep, 2009 | Pubmed ID: 19619132 Disruption of the Ubiquitin Proteasome System Following Axonal Stretch Injury Accelerates Progression to Secondary Axotomy Journal of Neurotrauma. May, 2009 | Pubmed ID: 19416018 Redefining the Role of Metallothionein Within the Injured Brain: Extracellular Metallothioneins Play an Important Role in the Astrocyte-neuron Response to Injury The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18334482 Metallothionein-IIA Promotes Neurite Growth Via the Megalin Receptor Experimental Brain Research. Nov, 2007 | Pubmed ID: 17634932 Acute Reactive and Regenerative Changes in Mature Cortical Axons Following Injury Neuroreport. Feb, 2007 | Pubmed ID: 17314672 Identification and Characterization of a Population of Motile Neurons in Long-term Cortical Culture Cell Motility and the Cytoskeleton. Apr, 2007 | Pubmed ID: 17245771 Metallothioneins I and II: Neuroprotective Significance During CNS Pathology The International Journal of Biochemistry & Cell Biology. 2007 | Pubmed ID: 17097331 Mild Axonal Stretch Injury in Vitro Induces a Progressive Series of Neurofilament Alterations Ultimately Leading to Delayed Axotomy Journal of Neurotrauma. Oct, 2005 | Pubmed ID: 16238485 Glutamate Induces Rapid Loss of Axonal Neurofilament Proteins from Cortical Neurons in Vitro Experimental Neurology. Jun, 2005 | Pubmed ID: 15869950 Spinal Cord Tissue Affects Ensheathing Cell Proliferation and Apoptosis Neuroreport. May, 2005 | Pubmed ID: 15858416 Protective Role of Metallothioneins in the Injured Mammalian Brain Reviews in the Neurosciences. 2004 | Pubmed ID: 15357139 Neuron-glia Communication: Metallothionein Expression is Specifically Up-regulated by Astrocytes in Response to Neuronal Injury Journal of Neurochemistry. Jan, 2004 | Pubmed ID: 14690533 Metallothionein-IIA Promotes Initial Neurite Elongation and Postinjury Reactive Neurite Growth and Facilitates Healing After Focal Cortical Brain Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2003 | Pubmed ID: 12716941 Sheep Have an Unusual Variant of the Brain-specific Metallothionein, Metallothionein-III The Biochemical Journal. Jul, 2002 | Pubmed ID: 11931634 Déclenchement Stress cellulaire et la mort Utilisation conventionnelle UV Laser Microscopie confocale Marco Morsch1, Rowan A. W. Radford1, Emily K. Don1, Albert Lee1, Elinor Hortle1, Nicholas J. Cole1, Roger S. Chung1 1Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University Neuroscience
Déclenchement Stress cellulaire et la mort Utilisation conventionnelle UV Laser Microscopie confocale Marco Morsch1, Rowan A. W. Radford1, Emily K. Don1, Albert Lee1, Elinor Hortle1, Nicholas J. Cole1, Roger S. Chung1 1Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University Neuroscience