Roger Markwald Department of Bioengineering Clemson University Biography Publications Institution JoVE Articles Roger Markwald has not added a biography. If you are Roger Markwald and would like to personalize this page please email our Author Liaison for assistance. Publications Genetic Association Analyses Highlight Biological Pathways Underlying Mitral Valve Prolapse Nature Genetics. Aug, 2015 | Pubmed ID: 26301497 Mutations in DCHS1 Cause Mitral Valve Prolapse Nature. Sep, 2015 | Pubmed ID: 26258302 Interactions Between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer Frontiers in Immunology. 2015 | Pubmed ID: 25999946 Isothiocyanate Analogs Targeting CD44 Receptor As an Effective Strategy Against Colon Cancer Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents. Aug, 2014 | Pubmed ID: 25013352 Study of Droplet Formation Process During Drop-on-demand Inkjetting of Living Cell-laden Bioink Langmuir : the ACS Journal of Surfaces and Colloids. Aug, 2014 | Pubmed ID: 25005170 Engineering Alginate As Bioink for Bioprinting Acta Biomaterialia. Oct, 2014 | Pubmed ID: 24998183 3D Printing Facilitated Scaffold-free Tissue Unit Fabrication Biofabrication. Jun, 2014 | Pubmed ID: 24717646 Periostin Induces Intracellular Cross-talk Between Kinases and Hyaluronan in Atrioventricular Valvulogenesis The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24469446 Overexpression of C-Met and CD44v6 Receptors Contributes to Autocrine TGF-β1 Signaling in Interstitial Lung Disease The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24324260 Novel Di-tertiary-butyl Phenylhydrazones As Dual Cyclooxygenase-2/5-lipoxygenase Inhibitors: Synthesis, COX/LOX Inhibition, Molecular Modeling, and Insights into Their Cytotoxicities Bioorganic & Medicinal Chemistry Letters. Jan, 2014 | Pubmed ID: 24295787 The Role of Periostin in Tissue Remodeling Across Health and Disease Cellular and Molecular Life Sciences : CMLS. Apr, 2014 | Pubmed ID: 24146092 Cellularized Microcarriers As Adhesive Building Blocks for Fabrication of Tubular Tissue Constructs Annals of Biomedical Engineering. Jul, 2014 | Pubmed ID: 23943070 Laser Patterning for the Study of MSC Cardiogenic Differentiation at the Single-cell Level Light, Science & Applications. 2013 | Pubmed ID: 24527266 Methodology for the Evaluation of Double-Layered Microcapsule Formability Zone in Compound Nozzle Jetting Based on Growth Rate Ratio Journal of Fluids Engineering. May, 2013 | Pubmed ID: 23904666 MiR-21 Represses Pdcd4 During Cardiac Valvulogenesis Development (Cambridge, England). May, 2013 | Pubmed ID: 23578931 Mesenchymal Stem Cell-Cardiomyocyte Interactions Under Defined Contact Modes on Laser-Patterned Biochips PloS One. 2013 | Pubmed ID: 23418583 Myosin Filament Assembly Onto Myofibrils in Live Neonatal Cardiomyocytes Observed by TPEF-SHG Microscopy Cardiovascular Research. Feb, 2013 | Pubmed ID: 23118131 Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice Journal of Neonatal Biology. Jan, 2012 | Pubmed ID: 25383261 Endocardial Cells Form the Coronary Arteries by Angiogenesis Through Myocardial-endocardial VEGF Signaling Cell. Nov, 2012 | Pubmed ID: 23178125 Cardiogenic Regulation of Stem-Cell Electrical Properties in a Laser-Patterned Biochip Cellular and Molecular Bioengineering. Sep, 2012 | Pubmed ID: 23139730 Developmental Basis for Filamin-A-associated Myxomatous Mitral Valve Disease Cardiovascular Research. Oct, 2012 | Pubmed ID: 22843703 Scaffold-free Inkjet Printing of Three-dimensional Zigzag Cellular Tubes Biotechnology and Bioengineering. Dec, 2012 | Pubmed ID: 22767299 Atrioventricular Valve Development: New Perspectives on an Old Theme Differentiation; Research in Biological Diversity. Jul, 2012 | Pubmed ID: 22579502 Translational Research on the Mitral Valve: from Developmental Mechanisms to New Therapies Journal of Cardiovascular Translational Research. Dec, 2011 | Pubmed ID: 21901526 Recruitment of Bone Marrow-derived Valve Interstitial Cells is a Normal Homeostatic Process Journal of Molecular and Cellular Cardiology. Dec, 2011 | Pubmed ID: 21871458 Megahertz Streak-mode Fourier Domain Optical Coherence Tomography Journal of Biomedical Optics. Jun, 2011 | Pubmed ID: 21721817 Organ Printing: from Bioprinter to Organ Biofabrication Line Current Opinion in Biotechnology. Oct, 2011 | Pubmed ID: 21419621 Accessory Atrioventricular Myocardial Pathways in Mouse Heart Development: Substrate for Supraventricular Tachycardias Pediatric Research. Jul, 2011 | Pubmed ID: 21399557 Hyaluronan-CD44 Interactions As Potential Targets for Cancer Therapy The FEBS Journal. May, 2011 | Pubmed ID: 21362138 Cardiac Fibrosis in Mice with Hypertrophic Cardiomyopathy is Mediated by Non-myocyte Proliferation and Requires Tgf-β The Journal of Clinical Investigation. Oct, 2010 | Pubmed ID: 20811150 Tissue Spheroid Fusion-based in Vitro Screening Assays for Analysis of Tissue Maturation Journal of Tissue Engineering and Regenerative Medicine. Dec, 2010 | Pubmed ID: 20603872 Developmental Basis of Adult Cardiovascular Diseases: Valvular Heart Diseases Annals of the New York Academy of Sciences. Feb, 2010 | Pubmed ID: 20201901 Stromal Hyaluronan Interaction with Epithelial CD44 Variants Promotes Prostate Cancer Invasiveness by Augmenting Expression and Function of Hepatocyte Growth Factor and Androgen Receptor The Journal of Biological Chemistry. Jun, 2010 | Pubmed ID: 20200161 Towards Organ Printing: Engineering an Intra-organ Branched Vascular Tree Expert Opinion on Biological Therapy. Mar, 2010 | Pubmed ID: 20132061 Computational Modeling of Epithelial-mesenchymal Transformations Bio Systems. Apr, 2010 | Pubmed ID: 20005917 Periostin Mediates Vascular Smooth Muscle Cell Migration Through the Integrins Alphavbeta3 and Alphavbeta5 and Focal Adhesion Kinase (FAK) Pathway Atherosclerosis. Feb, 2010 | Pubmed ID: 19695571 The Many Facets of the Matricelluar Protein Periostin During Cardiac Development, Remodeling, and Pathophysiology Journal of Cell Communication and Signaling. Dec, 2009 | Pubmed ID: 19798597 Lack of Periostin Leads to Suppression of Notch1 Signaling and Calcific Aortic Valve Disease Physiological Genomics. Nov, 2009 | Pubmed ID: 19723774 Periostin Promotes a Fibroblastic Lineage Pathway in Atrioventricular Valve Progenitor Cells Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2009 | Pubmed ID: 19334280 Delivery of CD44 ShRNA/nanoparticles Within Cancer Cells: Perturbation of Hyaluronan/CD44v6 Interactions and Reduction in Adenoma Growth in Apc Min/+ MICE The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19246453 Organ Printing: Tissue Spheroids As Building Blocks Biomaterials. Apr, 2009 | Pubmed ID: 19176247 Rapid Biofabrication of Tubular Tissue Constructs by Centrifugal Casting in a Decellularized Natural Scaffold with Laser-machined Micropores Journal of Materials Science. Materials in Medicine. Jan, 2009 | Pubmed ID: 18807150 Relating Cell and Tissue Mechanics: Implications and Applications Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2008 | Pubmed ID: 18729216 Tissue-specific ShRNA Delivery: a Novel Approach for Gene Therapy in Cancer Connective Tissue Research. 2008 | Pubmed ID: 18661357 Hyaluronan, CD44, and Cyclooxygenase-2 in Colon Cancer Connective Tissue Research. 2008 | Pubmed ID: 18661347 Nanotechnology in Vascular Tissue Engineering: from Nanoscaffolding Towards Rapid Vessel Biofabrication Trends in Biotechnology. Jun, 2008 | Pubmed ID: 18423666 Neonatal and Adult Cardiovascular Pathophysiological Remodeling and Repair: Developmental Role of Periostin Annals of the New York Academy of Sciences. Mar, 2008 | Pubmed ID: 18375575 Tissue Engineering by Self-assembly of Cells Printed into Topologically Defined Structures Tissue Engineering. Part A. Mar, 2008 | Pubmed ID: 18333793 Epicardium-derived Cells in Development of Annulus Fibrosis and Persistence of Accessory Pathways Circulation. Mar, 2008 | Pubmed ID: 18332266 Hyaluronan Constitutively Regulates Activation of COX-2-mediated Cell Survival Activity in Intestinal Epithelial and Colon Carcinoma Cells The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18326857 Periostin Regulates Atrioventricular Valve Maturation Developmental Biology. Apr, 2008 | Pubmed ID: 18313657 Periostin is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart Circulation Research. Apr, 2008 | Pubmed ID: 18296617 Periostin Expression by Epicardium-derived Cells is Involved in the Development of the Atrioventricular Valves and Fibrous Heart Skeleton Differentiation; Research in Biological Diversity. Sep, 2008 | Pubmed ID: 18294225 BMP-2 Induces Cell Migration and Periostin Expression During Atrioventricular Valvulogenesis Developmental Biology. Mar, 2008 | Pubmed ID: 18261719 Bioreactor-free Tissue Engineering: Directed Tissue Assembly by Centrifugal Casting Expert Opinion on Biological Therapy. Feb, 2008 | Pubmed ID: 18194071 Organ Printing: Promises and Challenges Regenerative Medicine. Jan, 2008 | Pubmed ID: 18154465 Periostin: More Than Just an Adhesion Molecule Circulation Research. Aug, 2007 | Pubmed ID: 17673682 Valvulogenesis: the Moving Target Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Aug, 2007 | Pubmed ID: 17569640 Transitions in Early Embryonic Atrioventricular Valvular Function Correspond with Changes in Cushion Biomechanics That Are Predictable by Tissue Composition Circulation Research. May, 2007 | Pubmed ID: 17478728 Functional BMP Receptor in Endocardial Cells is Required in Atrioventricular Cushion Mesenchymal Cell Formation in Chick Developmental Biology. Jun, 2007 | Pubmed ID: 17449024 The Next Frontier in Cardiovascular Developmental Biology--an Integrated Approach to Adult Disease? Nature Clinical Practice. Cardiovascular Medicine. Feb, 2007 | Pubmed ID: 17245398 Versican Proteolysis Mediates Myocardial Regression During Outflow Tract Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2007 | Pubmed ID: 17226818 Periostin Regulates Collagen Fibrillogenesis and the Biomechanical Properties of Connective Tissues Journal of Cellular Biochemistry. Jun, 2007 | Pubmed ID: 17226767 Persistence of Functional Atrioventricular Accessory Pathways in Postseptated Embryonic Avian Hearts: Implications for Morphogenesis and Functional Maturation of the Cardiac Conduction System Circulation. Jan, 2007 | Pubmed ID: 17190860 Periostin Promotes Atrioventricular Mesenchyme Matrix Invasion and Remodeling Mediated by Integrin Signaling Through Rho/PI 3-kinase Developmental Biology. Feb, 2007 | Pubmed ID: 17070513 Quantitative Volumetric Analysis of Cardiac Morphogenesis Assessed Through Micro-computed Tomography Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2007 | Pubmed ID: 17013892 Recruitment of New Cells into the Postnatal Heart: Potential Modification of Phenotype by Periostin Annals of the New York Academy of Sciences. Oct, 2006 | Pubmed ID: 17132772 American Association of Anatomists Meeting on Regenerative Medicine Expert Opinion on Biological Therapy. Jul, 2006 | Pubmed ID: 16805712 In Vitro Self-assembly of Proepicardial Cell Aggregates: an Embryonic Vasculogenic Model for Vascular Tissue Engineering The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Jul, 2006 | Pubmed ID: 16761281 Cardiovascular Tissue Engineering I. Perfusion Bioreactors: a Review Journal of Long-term Effects of Medical Implants. 2006 | Pubmed ID: 16700652 An in Vivo Analysis of Hematopoietic Stem Cell Potential: Hematopoietic Origin of Cardiac Valve Interstitial Cells Circulation Research. Mar, 2006 | Pubmed ID: 16456103 Tannic Acid Mimicking Dendrimers As Small Intestine Submucosa Stabilizing Nanomordants Biomaterials. Feb, 2006 | Pubmed ID: 16102811 Stem Cell Treatment of the Heart: a Review of Its Current Status on the Brink of Clinical Experimentation Texas Heart Institute Journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 2005 | Pubmed ID: 16429891 On the Role of Shear Stress in Cardiogenesis Endothelium : Journal of Endothelial Cell Research. Sep-Dec, 2005 | Pubmed ID: 16410225 Classics in Anatomy: Keith Porter's Harvey Lecture, "the Submicroscopic Morphology of Protoplasm" The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Dec, 2005 | Pubmed ID: 16265624 Periostin Family of Proteins: Therapeutic Targets for Heart Disease The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Dec, 2005 | Pubmed ID: 16240445 Multiple Stem Cell Populations Contribute to the Formation of the Myocardium Annals of the New York Academy of Sciences. Jun, 2005 | Pubmed ID: 16093483 Detection of Betaig-H3, a TGFbeta Induced Gene, During Cardiac Development and Its Complementary Pattern with Periostin Anatomy and Embryology. Aug, 2005 | Pubmed ID: 16034610 Fabrication of Tubular Tissue Constructs by Centrifugal Casting of Cells Suspended in an in Situ Crosslinkable Hyaluronan-gelatin Hydrogel Biomaterials. Dec, 2005 | Pubmed ID: 16023201 Immunolocalization of Chick Periostin Protein in the Developing Heart The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. May, 2005 | Pubmed ID: 15803479 Can Routine Commercial Cord Blood Banking Be Scientifically and Ethically Justified? PLoS Medicine. Feb, 2005 | Pubmed ID: 15737000 Identification and Detection of the Periostin Gene in Cardiac Development The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Dec, 2004 | Pubmed ID: 15532025 Cellular Recruitment and the Development of the Myocardium Developmental Biology. Oct, 2004 | Pubmed ID: 15385154 Bone Morphogenetic Protein-2 Can Mediate Myocardial Regulation of Atrioventricular Cushion Mesenchymal Cell Formation in Mice Developmental Biology. May, 2004 | Pubmed ID: 15110716 Periostin is Expressed Within the Developing Teeth at the Sites of Epithelial-mesenchymal Interaction Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2004 | Pubmed ID: 15042709 Engineering Biological Structures of Prescribed Shape Using Self-assembling Multicellular Systems Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14981244 Endodermal Growth Factors Promote Endocardial Precursor Cell Formation from Precardiac Mesoderm Developmental Biology. Nov, 2003 | Pubmed ID: 14568545 Development of the Cardiac Conduction System. Introduction Novartis Foundation Symposium. 2003 | Pubmed ID: 12956320 Desktop Organ Printing Anatomical Record. Part B, New Anatomist. Jul, 2003 | Pubmed ID: 12913952 The 2003 Henry Gray Award Anatomical Record. Part B, New Anatomist. Jul, 2003 | Pubmed ID: 12833271 Perfusion Bioreactor for Vascular Tissue Engineering with Capacities for Longitudinal Stretch The Journal of Craniofacial Surgery. May, 2003 | Pubmed ID: 12826805 Fibroblast Growth Factor (FGF)-4 Can Induce Proliferation of Cardiac Cushion Mesenchymal Cells During Early Valve Leaflet Formation Developmental Biology. Jun, 2003 | Pubmed ID: 12798286 Cell and Organ Printing 2: Fusion of Cell Aggregates in Three-dimensional Gels The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Jun, 2003 | Pubmed ID: 12740943 Organ Printing: Computer-aided Jet-based 3D Tissue Engineering Trends in Biotechnology. Apr, 2003 | Pubmed ID: 12679063 Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer Sarah Grace Dennis1, Thomas Trusk2, Dylan Richards3, Jia Jia3, Yu Tan3, Ying Mei3, Stephen Fann1, Roger Markwald3, Michael Yost1 1Department of Surgery, Medical University of South Carolina, 2Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 3Department of Bioengineering, Clemson University JoVE 53156 Bioengineering
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer Sarah Grace Dennis1, Thomas Trusk2, Dylan Richards3, Jia Jia3, Yu Tan3, Ying Mei3, Stephen Fann1, Roger Markwald3, Michael Yost1 1Department of Surgery, Medical University of South Carolina, 2Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 3Department of Bioengineering, Clemson University JoVE 53156 Bioengineering