Ronald T. Hay MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences University of Dundee Biography Publications Institution JoVE Articles Ronald T. Hay has not added a biography. If you are Ronald T. Hay and would like to personalize this page please email our Author Liaison for assistance. Publications Tetramerization-defects of P53 Result in Aberrant Ubiquitylation and Transcriptional Activity Molecular Oncology. Apr, 2014 | Pubmed ID: 24816189 Proteome-Wide Identification of SUMO2 Modification Sites Science Signaling. 2014 | Pubmed ID: 24782567 E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin Cancer Research. Apr, 2014 | Pubmed ID: 24686174 SUMO Chain-induced Dimerization Activates RNF4 Molecular Cell. Mar, 2014 | Pubmed ID: 24656128 PML Isoforms in Response to Arsenic: High Resolution Analysis of PML Body Structure and Degradation Characteristics Journal of Cell Science. Nov, 2013 | Pubmed ID: 24190887 BC-box Protein Domain-related Mechanism for VHL Protein Degradation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24145437 A Role for Paralog-specific Sumoylation in Histone Deacetylase 1 Stability Journal of Molecular Cell Biology. Dec, 2013 | Pubmed ID: 24068740 Ube2W Conjugates Ubiquitin to α-amino Groups of Protein N-termini The Biochemical Journal. Jul, 2013 | Pubmed ID: 23560854 Decoding the SUMO Signal Biochemical Society Transactions. Apr, 2013 | Pubmed ID: 23514139 The P-body Component USP52/PAN2 is a Novel Regulator of HIF1A MRNA Stability The Biochemical Journal. Apr, 2013 | Pubmed ID: 23398456 Reanalysis of Phosphoproteomics Data Uncovers ADP-ribosylation Sites Nature Methods. Aug, 2012 | Pubmed ID: 22847107 Structure of a RING E3 Ligase and Ubiquitin-loaded E2 Primed for Catalysis Nature. Sep, 2012 | Pubmed ID: 22842904 SUMO-targeted Ubiquitin E3 Ligase RNF4 is Required for the Response of Human Cells to DNA Damage Genes & Development. Jun, 2012 | Pubmed ID: 22661230 SUMOylation of HNF4α Regulates Protein Stability and Hepatocyte Function Journal of Cell Science. Aug, 2012 | Pubmed ID: 22505616 Detection and Quantitation of SUMO Chains by Mass Spectrometry Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22350890 Stable-isotope Labeling with Amino Acids in Nematodes Nature Methods. 2011 | Pubmed ID: 21874007 Mechanism of Ubiquitylation by Dimeric RING Ligase RNF4 Nature Structural & Molecular Biology. Sep, 2011 | Pubmed ID: 21857666 Absolute SILAC-compatible Expression Strain Allows Sumo-2 Copy Number Determination in Clinical Samples Journal of Proteome Research. Oct, 2011 | Pubmed ID: 21830832 Comparative Proteomic Analysis Identifies a Role for SUMO in Protein Quality Control Science Signaling. 2011 | Pubmed ID: 21693764 Purification and Identification of Endogenous PolySUMO Conjugates EMBO Reports. Feb, 2011 | Pubmed ID: 21252943 The SUMO Protease SENP6 is a Direct Regulator of PML Nuclear Bodies Molecular Biology of the Cell. Jan, 2011 | Pubmed ID: 21148299 Functional Interactions Between Ubiquitin E2 Enzymes and TRIM Proteins The Biochemical Journal. Mar, 2011 | Pubmed ID: 21143188 Arsenic-induced SUMO-dependent Recruitment of RNF4 into PML Nuclear Bodies Molecular Biology of the Cell. Dec, 2010 | Pubmed ID: 20943951 SUMOylation of the GTPase Rac1 is Required for Optimal Cell Migration Nature Cell Biology. Nov, 2010 | Pubmed ID: 20935639 Post-translational Modification by SUMO Toxicology. Dec, 2010 | Pubmed ID: 20674646 High-stringency Tandem Affinity Purification of Proteins Conjugated to Ubiquitin-like Moieties Nature Protocols. May, 2010 | Pubmed ID: 20431533 Oligomerization Conditions Mdm2-mediated Efficient P53 Polyubiquitylation but Not Its Proteasomal Degradation The International Journal of Biochemistry & Cell Biology. May, 2010 | Pubmed ID: 20080206 Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation European Journal of Organic Chemistry. Nov, 2009 | Pubmed ID: 23606807 Detection of Protein SUMOylation in Vivo Nature Protocols. 2009 | Pubmed ID: 19730420 An Additional Role for SUMO in Ubiquitin-mediated Proteolysis Nature Reviews. Molecular Cell Biology. Aug, 2009 | Pubmed ID: 19474794 System-wide Changes to SUMO Modifications in Response to Heat Shock Science Signaling. 2009 | Pubmed ID: 19471022 Characterization of SENP7, a SUMO-2/3-specific Isopeptidase The Biochemical Journal. Jul, 2009 | Pubmed ID: 19392659 FRET-based in Vitro Assays for the Analysis of SUMO Protease Activities Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19107423 Medea SUMOylation Restricts the Signaling Range of the Dpp Morphogen in the Drosophila Embryo Genes & Development. Sep, 2008 | Pubmed ID: 18794353 Single-stranded DNA-binding Protein HSSB1 is Critical for Genomic Stability Nature. May, 2008 | Pubmed ID: 18449195 RNF4 is a Poly-SUMO-specific E3 Ubiquitin Ligase Required for Arsenic-induced PML Degradation Nature Cell Biology. May, 2008 | Pubmed ID: 18408734 Conjugation of Human Topoisomerase 2 Alpha with Small Ubiquitin-like Modifiers 2/3 in Response to Topoisomerase Inhibitors: Cell Cycle Stage and Chromosome Domain Specificity Cancer Research. Apr, 2008 | Pubmed ID: 18381449 Quantitative Analysis of Multi-protein Interactions Using FRET: Application to the SUMO Pathway Protein Science : a Publication of the Protein Society. Apr, 2008 | Pubmed ID: 18359863 NF-kappaB is a Critical Regulator of the Survival of Rodent and Human Hepatic Myofibroblasts Journal of Hepatology. Apr, 2008 | Pubmed ID: 18279996 Ribosomal Proteins Are Targets for the NEDD8 Pathway EMBO Reports. Mar, 2008 | Pubmed ID: 18274552 In Vivo Identification of Human Small Ubiquitin-like Modifier Polymerization Sites by High Accuracy Mass Spectrometry and an in Vitro to in Vivo Strategy Molecular & Cellular Proteomics : MCP. Jan, 2008 | Pubmed ID: 17938407 SUMO Modification Regulates MafB-driven Macrophage Differentiation by Enabling Myb-dependent Transcriptional Repression Molecular and Cellular Biology. Aug, 2007 | Pubmed ID: 17548468 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360386 siRNA Screening naar Ubiquitin en Ubiquitin-achtig systeem regulatoren van biologische pathways identificeren in gekweekte zoogdiercellen John S. Bett1, Adel F. M. Ibrahim1, Amit K. Garg1, Sonia Rocha2, Ronald T. Hay1,2 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, 2Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee JoVE 51572 Biology
siRNA Screening naar Ubiquitin en Ubiquitin-achtig systeem regulatoren van biologische pathways identificeren in gekweekte zoogdiercellen John S. Bett1, Adel F. M. Ibrahim1, Amit K. Garg1, Sonia Rocha2, Ronald T. Hay1,2 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, 2Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee JoVE 51572 Biology