Sanford I. Bernstein Biology Department and Heart Institute San Diego State University Biography Publications Institution JoVE Articles Sanford I. Bernstein has not added a biography. If you are Sanford I. Bernstein and would like to personalize this page please email our Author Liaison for assistance. Publications Measuring Passive Myocardial Stiffness in Drosophila Melanogaster to Investigate Diastolic Dysfunction Journal of Cellular and Molecular Medicine. Jan, 2012 | Pubmed ID: 22225769 Alternative Relay and Converter Domains Tune Native Muscle Myosin Isoform Function in Drosophila Journal of Molecular Biology. Dec, 2011 | Pubmed ID: 22226837 Transgenic Expression and Purification of Myosin Isoforms Using the Drosophila Melanogaster Indirect Flight Muscle System Methods (San Diego, Calif.). Dec, 2011 | Pubmed ID: 22178692 Structural Basis for Myopathic Defects Engendered by Alterations in the Myosin Rod Journal of Molecular Biology. Dec, 2011 | Pubmed ID: 22037585 Disrupting the Myosin Converter-relay Interface Impairs Drosophila Indirect Flight Muscle Performance Biophysical Journal. Sep, 2011 | Pubmed ID: 21889448 The UNC-45 Chaperone is Critical for Establishing Myosin-based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model PloS One. 2011 | Pubmed ID: 21799905 Two Drosophila Myosin Transducer Mutants with Distinct Cardiomyopathies Have Divergent ADP and Actin Affinities The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21680742 A Mighty Small Heart: the Cardiac Proteome of Adult Drosophila Melanogaster PloS One. 2011 | Pubmed ID: 21541028 X-ray Crystal Structure of the UCS Domain-containing UNC-45 Myosin Chaperone from Drosophila Melanogaster Structure (London, England : 1993). Mar, 2011 | Pubmed ID: 21397190 Drosophila UNC-45 Accumulates in Embryonic Blastoderm and in Muscles, and is Essential for Muscle Myosin Stability Journal of Cell Science. Mar, 2011 | Pubmed ID: 21285246 Drosophila UNC-45 Prevents Heat-induced Aggregation of Skeletal Muscle Myosin and Facilitates Refolding of Citrate Synthase Biochemical and Biophysical Research Communications. May, 2010 | Pubmed ID: 20403336 Mutating the Converter-relay Interface of Drosophila Myosin Perturbs ATPase Activity, Actin Motility, Myofibril Stability and Flight Ability Journal of Molecular Biology. May, 2010 | Pubmed ID: 20362584 Alternative S2 Hinge Regions of the Myosin Rod Affect Myofibrillar Structure and Myosin Kinetics Biophysical Journal. May, 2009 | Pubmed ID: 19450484 Alternative Exon 9-encoded Relay Domains Affect More Than One Communication Pathway in the Drosophila Myosin Head Journal of Molecular Biology. Jun, 2009 | Pubmed ID: 19393244 The XXXVII European Muscle Conference: Oxford September 2008 Journal of Muscle Research and Cell Motility. 2008 | Pubmed ID: 19034677 Alternative Versions of the Myosin Relay Domain Differentially Respond to Load to Influence Drosophila Muscle Kinetics Biophysical Journal. Dec, 2008 | Pubmed ID: 18805920 Similarities and Differences Between Frozen-hydrated, Rigor Acto-S1 Complexes of Insect Flight and Chicken Skeletal Muscles Journal of Molecular Biology. Sep, 2008 | Pubmed ID: 18588896 Alternative Relay Domains of Drosophila Melanogaster Myosin Differentially Affect ATPase Activity, in Vitro Motility, Myofibril Structure and Muscle Function Journal of Molecular Biology. Jun, 2008 | Pubmed ID: 18462751 Myosin Transducer Mutations Differentially Affect Motor Function, Myofibril Structure, and the Performance of Skeletal and Cardiac Muscles Molecular Biology of the Cell. Feb, 2008 | Pubmed ID: 18045988 A Variable Domain Near the ATP-binding Site in Drosophila Muscle Myosin is Part of the Communication Pathway Between the Nucleotide and Actin-binding Sites Journal of Molecular Biology. May, 2007 | Pubmed ID: 17379245 Alternative S2 Hinge Regions of the Myosin Rod Differentially Affect Muscle Function, Myofibril Dimensions and Myosin Tail Length Journal of Molecular Biology. Apr, 2007 | Pubmed ID: 17316684 Transcriptional Regulation of the Drosophila Melanogaster Muscle Myosin Heavy-chain Gene Gene Expression Patterns : GEP. Feb, 2007 | Pubmed ID: 17194628 Passive Stiffness in Drosophila Indirect Flight Muscle Reduced by Disrupting Paramyosin Phosphorylation, but Not by Embryonic Myosin S2 Hinge Substitution Biophysical Journal. Dec, 2006 | Pubmed ID: 17012313 AlphaB-crystallin Maintains Skeletal Muscle Myosin Enzymatic Activity and Prevents Its Aggregation Under Heat-shock Stress Journal of Molecular Biology. May, 2006 | Pubmed ID: 16546210 An Alternative Domain Near the ATP Binding Pocket of Drosophila Myosin Affects Muscle Fiber Kinetics Biophysical Journal. Apr, 2006 | Pubmed ID: 16399836 An Alternative Domain Near the Nucleotide-binding Site of Drosophila Muscle Myosin Affects ATPase Kinetics Journal of Molecular Biology. Oct, 2005 | Pubmed ID: 16154586 Paramyosin Phosphorylation Site Disruption Affects Indirect Flight Muscle Stiffness and Power Generation in Drosophila Melanogaster Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16020538 Drosophila Paramyosin is Important for Myoblast Fusion and Essential for Myofibril Formation The Journal of Cell Biology. Nov, 2004 | Pubmed ID: 15557126 Passive Stiffness of Drosophila IFM Myofibrils: a Novel, High Accuracy Measurement Method Journal of Muscle Research and Cell Motility. 2004 | Pubmed ID: 15548865 Alternative N-terminal Regions of Drosophila Myosin Heavy Chain Tune Muscle Kinetics for Optimal Power Output Biophysical Journal. Sep, 2004 | Pubmed ID: 15345559 Kinetic Analysis of Drosophila Muscle Myosin Isoforms Suggests a Novel Mode of Mechanochemical Coupling The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14506231 UCS Proteins: Managing the Myosin Motor Current Biology : CB. Jul, 2003 | Pubmed ID: 12842031 Drosophila Paramyosin is Important for Myoblast Fusion and Essential for Myofibril Formation The Journal of Cell Biology. Mar, 2003 | Pubmed ID: 12642615 Variable N-terminal Regions of Muscle Myosin Heavy Chain Modulate ATPase Rate and Actin Sliding Velocity The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12606545 The Converter Domain Modulates Kinetic Properties of Drosophila Myosin American Journal of Physiology. Cell Physiology. Apr, 2003 | Pubmed ID: 12477668 The Myosin Converter Domain Modulates Muscle Performance Nature Cell Biology. Apr, 2002 | Pubmed ID: 11901423 חצי אוטומטיות Heartbeat ניתוח אופטי של לבבות קטנים Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biology
חצי אוטומטיות Heartbeat ניתוח אופטי של לבבות קטנים Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biology