Sangeeta N. Bhatia Institute for Medical Engineering and Science Massachusetts Institute of Technology Biography Publications Institution JoVE Articles Sangeeta N. Bhatia has not added a biography. If you are Sangeeta N. Bhatia and would like to personalize this page please email our Author Liaison for assistance. Publications Adipose Tissue and Skeletal Muscle Wasting Precede Clinical Diagnosis of Pancreatic Cancer Nature Communications. Jul, 2023 | Pubmed ID: 37463915 CRISPR-Cas-amplified Urinary Biomarkers for Multiplexed and Portable Cancer Diagnostics Nature Nanotechnology. Jul, 2023 | Pubmed ID: 37095220 Low Protease Activity in B Cell Follicles Promotes Retention of Intact Antigens After Immunization Science (New York, N.Y.). Jan, 2023 | Pubmed ID: 36701450 Multiscale Profiling of Protease Activity in Cancer Nature Communications. Oct, 2022 | Pubmed ID: 36192379 Ebola Virus Infection Induces a Delayed Type I IFN Response in Bystander Cells and the Shutdown of Key Liver Genes in Human IPSC-derived Hepatocytes Stem Cell Reports. Oct, 2022 | Pubmed ID: 36084636 Conditional Antimicrobial Peptide Therapeutics ACS Nano. Oct, 2022 | Pubmed ID: 35980829 Direct Capture of Neutralized RBD Enables Rapid Point-of-care Assessment of SARS-CoV-2 Neutralizing Antibody Titer Cell Reports Methods. Aug, 2022 | Pubmed ID: 35942328 Cancer Nanomedicine Nature Reviews. Cancer. Oct, 2022 | Pubmed ID: 35941223 A Vascularized Model of the Human Liver Mimics Regenerative Responses Proceedings of the National Academy of Sciences of the United States of America. Jul, 2022 | Pubmed ID: 35763565 Host Protease Activity Classifies Pneumonia Etiology Proceedings of the National Academy of Sciences of the United States of America. Jun, 2022 | Pubmed ID: 35696579 A Single-cell Liver Atlas of Plasmodium Vivax Infection Cell Host & Microbe. Jul, 2022 | Pubmed ID: 35443155 Ionic Liquid-Mediated Transdermal Delivery of Thrombosis-Detecting Nanosensors Advanced Healthcare Materials. Jun, 2022 | Pubmed ID: 35182107 Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jan, 2022 | Pubmed ID: 34786888 Protease Activity Sensors Enable Real-time Treatment Response Monitoring in Lymphangioleiomyomatosis The European Respiratory Journal. Apr, 2022 | Pubmed ID: 34561286 Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity Hepatology Communications. Jan, 2022 | Pubmed ID: 34558849 Virtual Undergraduate Research Experiences: More Than a Pandemic Stopgap Med (New York, N.Y.). Feb, 2021 | Pubmed ID: 35187514 Synthetic Biomarkers: a Twenty-first Century Path to Early Cancer Detection Nature Reviews. Cancer. Oct, 2021 | Pubmed ID: 34489588 Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection ACS Synthetic Biology. Sep, 2021 | Pubmed ID: 34464083 Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function ACS Chemical Biology. Sep, 2021 | Pubmed ID: 34427427 Microenvironment-triggered Multimodal Precision Diagnostics Nature Materials. Oct, 2021 | Pubmed ID: 34267368 Two Chemoattenuated PfSPZ Malaria Vaccines Induce Sterile Hepatic Immunity Nature. Jul, 2021 | Pubmed ID: 34194041 Opening the Path to Biotech Science (New York, N.Y.). May, 2021 | Pubmed ID: 33958450 Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization ACS Infectious Diseases. Apr, 2021 | Pubmed ID: 33689277 Activatable Zymography Probes Enable Localization of Protease Dysregulation in Cancer Cancer Research. Jan, 2021 | Pubmed ID: 33106334 Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers Advanced Functional Materials. Nov, 2020 | Pubmed ID: 33776613 Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues Advanced Functional Materials. Nov, 2020 | Pubmed ID: 33613149 Peptide Spiders: Peptide-Polymer Conjugates to Traffic Nucleic Acids Molecular Pharmaceutics. Sep, 2020 | Pubmed ID: 32786959 Mapping Functional Humoral Correlates of Protection Against Malaria Challenge Following RTS,S/AS01 Vaccination Science Translational Medicine. Jul, 2020 | Pubmed ID: 32718991 Engineering Synthetic Breath Biomarkers for Respiratory Disease Nature Nanotechnology. Sep, 2020 | Pubmed ID: 32690884 Nanoparticle Delivery of Immunostimulatory Oligonucleotides Enhances Response to Checkpoint Inhibitor Therapeutics Proceedings of the National Academy of Sciences of the United States of America. Jun, 2020 | Pubmed ID: 32493746 Pharmacokinetic Tuning of Protein-antigen Fusions Enhances the Immunogenicity of T-cell Vaccines Nature Biomedical Engineering. Jun, 2020 | Pubmed ID: 32483299 Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring Trends in Molecular Medicine. May, 2020 | Pubmed ID: 32359477 Urinary Detection of Lung Cancer in Mice Via Noninvasive Pulmonary Protease Profiling Science Translational Medicine. Apr, 2020 | Pubmed ID: 32238573 Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma Cancer Research. 04, 2020 | Pubmed ID: 32029550 Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging ACS Synthetic Biology. Feb, 2020 | Pubmed ID: 31922737 Expansion, in Vivo-ex Vivo Cycling, and Genetic Manipulation of Primary Human Hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31915293 Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing Angewandte Chemie (International Ed. in English). 02, 2020 | Pubmed ID: 31747099 Targeting Liver Stage Malaria with Metformin JCI Insight. Dec, 2019 | Pubmed ID: 31852843 Non-viral Delivery of CRISPR/Cas9 Complex Using CRISPR-GPS Nanocomplexes Nanoscale. Nov, 2019 | Pubmed ID: 31670340 Tumor Penetrating Nanomedicine Targeting Both an OncomiR and an Oncogene in Pancreatic Cancer Oncotarget. Sep, 2019 | Pubmed ID: 31523393 Renal Clearable Catalytic Gold Nanoclusters for in Vivo Disease Monitoring Nature Nanotechnology. Sep, 2019 | Pubmed ID: 31477801 Antimalarial Activity of Primaquine Operates Via a Two-step Biochemical Relay Nature Communications. Jul, 2019 | Pubmed ID: 31324806 Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles Cell. Apr, 2019 | Pubmed ID: 30929905 Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers Cell Metabolism. Mar, 2019 | Pubmed ID: 30840913 Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes Cancer Research. Apr, 2019 | Pubmed ID: 30755444 Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and MTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes Gastroenterology. 05, 2019 | Pubmed ID: 30641053 Author Correction: A Human Monoclonal Antibody Prevents Malaria Infection by Targeting a New Site of Vulnerability on the Parasite Nature Medicine. Jan, 2019 | Pubmed ID: 30552419 Protease Activity Sensors Noninvasively Classify Bacterial Infections and Antibiotic Responses EBioMedicine. Dec, 2018 | Pubmed ID: 30503861 A Sporozoite-based Vaccination Platform Against Human Malaria NPJ Vaccines. 2018 | Pubmed ID: 30155278 Classification of Prostate Cancer Using a Protease Activity Nanosensor Library Proceedings of the National Academy of Sciences of the United States of America. Sep, 2018 | Pubmed ID: 30126988 IRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic SiRNA Delivery to Pancreatic Cancer Molecular Cancer Therapeutics. Nov, 2018 | Pubmed ID: 30097486 Genome-scale Analysis Identifies Paralog Lethality As a Vulnerability of Chromosome 1p Loss in Cancer Nature Genetics. Jul, 2018 | Pubmed ID: 29955178 Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29736708 A Human Monoclonal Antibody Prevents Malaria Infection by Targeting a New Site of Vulnerability on the Parasite Nature Medicine. 05, 2018 | Pubmed ID: 29554083 In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites Cell Host & Microbe. Mar, 2018 | Pubmed ID: 29478773 Personalized RNA Medicine for Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2018 | Pubmed ID: 29330203 Engineered Livers for Infectious Diseases Cellular and Molecular Gastroenterology and Hepatology. 2018 | Pubmed ID: 29322086 Depolarization Signatures Map Gold Nanorods Within Biological Tissue Nature Photonics. 2017 | Pubmed ID: 29201136 A Robust Cell Culture System Supporting the Complete Life Cycle of Hepatitis B Virus Scientific Reports. Nov, 2017 | Pubmed ID: 29192196 Tumor-Penetrating Delivery of SiRNA Against TNFα to Human Vestibular Schwannomas Scientific Reports. Oct, 2017 | Pubmed ID: 29018206 Ultrasensitive Tumour-penetrating Nanosensors of Protease Activity Nature Biomedical Engineering. 2017 | Pubmed ID: 28970963 Potential Role of Intratumor Bacteria in Mediating Tumor Resistance to the Chemotherapeutic Drug Gemcitabine Science (New York, N.Y.). Sep, 2017 | Pubmed ID: 28912244 In Situ Expansion of Engineered Human Liver Tissue in a Mouse Model of Chronic Liver Disease Science Translational Medicine. Jul, 2017 | Pubmed ID: 28724577 Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas Aeruginosa Lung Infections Advanced Materials (Deerfield Beach, Fla.). Sep, 2017 | Pubmed ID: 28699173 Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers Scientific Reports. Mar, 2017 | Pubmed ID: 28361899 Porous Silicon-graphene Oxide Core-shell Nanoparticles for Targeted Delivery of SiRNA to the Injured Brain Nanoscale Horizons. Sep, 2016 | Pubmed ID: 29732165 Sustained-release Synthetic Biomarkers for Monitoring Thrombosis and Inflammation Using Point-of-care Compatible Readouts Advanced Functional Materials. May, 2016 | Pubmed ID: 29706854 Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling Nano Letters. Oct, 2016 | Pubmed ID: 27622711 Diversity-oriented Synthesis Yields Novel Multistage Antimalarial Inhibitors Nature. Oct, 2016 | Pubmed ID: 27602946 Host AMPK Is a Modulator of Plasmodium Liver Infection Cell Reports. Sep, 2016 | Pubmed ID: 27568570 Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors Angewandte Chemie (International Ed. in English). Sep, 2016 | Pubmed ID: 27554600 Infection of Laboratory Colonies of Anopheles Mosquitoes with Plasmodium Vivax from Cryopreserved Clinical Isolates International Journal for Parasitology. Oct, 2016 | Pubmed ID: 27456552 Synchronized Cycles of Bacterial Lysis for in Vivo Delivery Nature. Aug, 2016 | Pubmed ID: 27437587 Neuron-Targeted Nanoparticle for SiRNA Delivery to Traumatic Brain Injuries ACS Nano. Aug, 2016 | Pubmed ID: 27429164 Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted SiRNA Delivery to the Injured Brain Advanced Materials (Deerfield Beach, Fla.). Sep, 2016 | Pubmed ID: 27383373 Viral Genome Imaging of Hepatitis C Virus to Probe Heterogeneous Viral Infection and Responses to Antiviral Therapies Virology. Jul, 2016 | Pubmed ID: 27128351 Smart Nanosystems: Bio-inspired Technologies That Interact with the Host Environment Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26598694 Micropatterned Coculture of Primary Human Hepatocytes and Supportive Cells for the Study of Hepatotropic Pathogens Nature Protocols. Dec, 2015 | Pubmed ID: 26584444 Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity ACS Nano. Dec, 2015 | Pubmed ID: 26565752 Mathematical Framework for Activity-based Cancer Biomarkers Proceedings of the National Academy of Sciences of the United States of America. Oct, 2015 | Pubmed ID: 26417077 A Long-duration Dihydroorotate Dehydrogenase Inhibitor (DSM265) for Prevention and Treatment of Malaria Science Translational Medicine. Jul, 2015 | Pubmed ID: 26180101 Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors Cancer Research. Aug, 2015 | Pubmed ID: 26122846 CRISPR/Cas9 Cleavage of Viral DNA Efficiently Suppresses Hepatitis B Virus Scientific Reports. Jun, 2015 | Pubmed ID: 26035283 Programmable Probiotics for Detection of Cancer in Urine Science Translational Medicine. May, 2015 | Pubmed ID: 26019220 Degradable Hydrogels Derived from PEG-diacrylamide for Hepatic Tissue Engineering Journal of Biomedical Materials Research. Part A. Oct, 2015 | Pubmed ID: 25851120 Human IPSC-derived Hepatocyte-like Cells Support Plasmodium Liver-stage Infection in Vitro Stem Cell Reports. Mar, 2015 | Pubmed ID: 25660406 Aberrant Glycosylation Promotes Lung Cancer Metastasis Through Adhesion to Galectins in the Metastatic Niche Cancer Discovery. Feb, 2015 | Pubmed ID: 25421439 In Vitro Alterations Do Not Reflect a Requirement for Host Cell Cycle Progression During Plasmodium Liver Stage Infection Eukaryotic Cell. Jan, 2015 | Pubmed ID: 25416236 Patterning Vascular Networks in Vivo for Tissue Engineering Applications Tissue Engineering. Part C, Methods. May, 2015 | Pubmed ID: 25390971 Drug-induced Amplification of Nanoparticle Targeting to Tumors Nano Today. Oct, 2014 | Pubmed ID: 29731806 A Macro-to-Micro Interface for the Control of Cellular Organization Journal of Microelectromechanical Systems : a Joint IEEE and ASME Publication on Microstructures, Microactuators, Microsensors, and Microsystems. Apr, 2014 | Pubmed ID: 26167106 New Methods in Tissue Engineering: Improved Models for Viral Infection Annual Review of Virology. Nov, 2014 | Pubmed ID: 25893203 Host Cell Phosphatidylcholine is a Key Mediator of Malaria Parasite Survival During Liver Stage Infection Cell Host & Microbe. Dec, 2014 | Pubmed ID: 25498345 Deep, Noninvasive Imaging and Surgical Guidance of Submillimeter Tumors Using Targeted M13-stabilized Single-walled Carbon Nanotubes Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014 | Pubmed ID: 25214538 Disease Detection by Ultrasensitive Quantification of Microdosed Synthetic Urinary Biomarkers Journal of the American Chemical Society. Oct, 2014 | Pubmed ID: 25198059 Self-titrating Anticoagulant Nanocomplexes That Restore Homeostatic Regulation of the Coagulation Cascade ACS Nano. Sep, 2014 | Pubmed ID: 25119520 Microfluidic Organs-on-chips Nature Biotechnology. Aug, 2014 | Pubmed ID: 25093883 Modeling Host Interactions with Hepatitis B Virus Using Primary and Induced Pluripotent Stem Cell-derived Hepatocellular Systems Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 25092305 Mechanisms of Cooperation in Cancer Nanomedicine: Towards Systems Nanotechnology Trends in Biotechnology. Sep, 2014 | Pubmed ID: 25086728 Point-of-care Diagnostics for Noncommunicable Diseases Using Synthetic Urinary Biomarkers and Paper Microfluidics Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24567404 Micropatterned Cell-cell Interactions Enable Functional Encapsulation of Primary Hepatocytes in Hydrogel Microtissues Tissue Engineering. Part A. Aug, 2014 | Pubmed ID: 24498910 Weighing Nanoparticles in Solution at the Attogram Scale Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24474753 Hypoxia Promotes Liver-stage Malaria Infection in Primary Human Hepatocytes in Vitro Disease Models & Mechanisms. Feb, 2014 | Pubmed ID: 24291761 A Computational Framework for Identifying Design Guidelines to Increase the Penetration of Targeted Nanoparticles into Tumors Nano Today. Dec, 2013 | Pubmed ID: 25009578 Nanotechnology: Emerging Tools for Biology and Medicine Genes & Development. Nov, 2013 | Pubmed ID: 24240230 Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis ACS Nano. Oct, 2013 | Pubmed ID: 24015809 Plasmonic Photothermal Heating of Intraperitoneal Tumors Through the Use of an Implanted Near-infrared Source ACS Nano. Sep, 2013 | Pubmed ID: 23961973 A Microscale Human Liver Platform That Supports the Hepatic Stages of Plasmodium Falciparum and Vivax Cell Host & Microbe. Jul, 2013 | Pubmed ID: 23870318 Identification of Small Molecules for Human Hepatocyte Expansion and IPS Differentiation Nature Chemical Biology. Jun, 2013 | Pubmed ID: 23728495 Mitochondrial Localization and the Persistent Migration of Epithelial Cancer Cells Biophysical Journal. May, 2013 | Pubmed ID: 23663851 Geometric Control of Vascular Networks to Enhance Engineered Tissue Integration and Function Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23610423 Flow-based Pipeline for Systematic Modulation and Analysis of 3D Tumor Microenvironments Lab on a Chip. May, 2013 | Pubmed ID: 23563587 Mass-encoded Synthetic Biomarkers for Multiplexed Urinary Monitoring of Disease Nature Biotechnology. Jan, 2013 | Pubmed ID: 23242163 In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria ACS Synthetic Biology. Oct, 2012 | Pubmed ID: 23097750 Genetic Circuits in Salmonella Typhimurium ACS Synthetic Biology. Oct, 2012 | Pubmed ID: 23097749 Bioengineering Methods for Analysis of Cells in Vitro Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057744 A Combinatorial Extracellular Matrix Platform Identifies Cell-extracellular Matrix Interactions That Correlate with Metastasis Nature Communications. 2012 | Pubmed ID: 23047680 Critical Role for Lysyl Oxidase in Mesenchymal Stem Cell-driven Breast Cancer Malignancy Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23033492 Identification and Characterization of Receptor-specific Peptides for SiRNA Delivery ACS Nano. Oct, 2012 | Pubmed ID: 22909216 Cancer Vulnerabilities Unveiled by Genomic Loss Cell. Aug, 2012 | Pubmed ID: 22901813 Targeted Tumor-penetrating SiRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4 Science Translational Medicine. Aug, 2012 | Pubmed ID: 22896676 Rapid Casting of Patterned Vascular Networks for Perfusable Engineered Three-dimensional Tissues Nature Materials. Jul, 2012 | Pubmed ID: 22751181 A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease Science Translational Medicine. Feb, 2012 | Pubmed ID: 22378926 Modeling Hepatitis C Virus Infection Using Human Induced Pluripotent Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308485 DNA-templated Assembly of Droplet-derived PEG Microtissues Lab on a Chip. Sep, 2011 | Pubmed ID: 21776518 Humanized Mice with Ectopic Artificial Liver Tissues Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746904 Systematic Investigation of Genetic Vulnerabilities Across Cancer Cell Lines Reveals Lineage-specific Dependencies in Ovarian Cancer Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746896 Nanoparticles That Communicate in Vivo to Amplify Tumour Targeting Nature Materials. Jul, 2011 | Pubmed ID: 21685903 In-silico Patterning of Vascular Mesenchymal Cells in Three Dimensions PloS One. 2011 | Pubmed ID: 21633504 Nanoparticle-mediated Delivery of SiRNA Targeting Parp1 Extends Survival of Mice Bearing Tumors Derived from Brca1-deficient Ovarian Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2011 | Pubmed ID: 21187397 Multiplexed, High-throughput Analysis of 3D Microtissue Suspensions Integrative Biology : Quantitative Biosciences from Nano to Macro. Oct, 2010 | Pubmed ID: 20820630 Ligand-clustered "patchy" Nanoparticles for Modulated Cellular Uptake and in Vivo Tumor Targeting Angewandte Chemie (International Ed. in English). Sep, 2010 | Pubmed ID: 20740515 Single Cell Trapping and DNA Damage Analysis Using Microwell Arrays Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534572 Microfluidics-integrated Time-lapse Imaging for Analysis of Cellular Dynamics Integrative Biology : Quantitative Biosciences from Nano to Macro. Jun, 2010 | Pubmed ID: 20532320 Targeting of Drugs and Nanoparticles to Tumors The Journal of Cell Biology. Mar, 2010 | Pubmed ID: 20231381 Cooperative Nanoparticles for Tumor Detection and Photothermally Triggered Drug Delivery Advanced Materials (Deerfield Beach, Fla.). Feb, 2010 | Pubmed ID: 20217810 Persistent Hepatitis C Virus Infection in Microscale Primary Human Hepatocyte Cultures Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133632 Real-time Imaging of Hepatitis C Virus Infection Using a Fluorescent Cell-based Reporter System Nature Biotechnology. Feb, 2010 | Pubmed ID: 20118917 Cooperative Nanomaterial System to Sensitize, Target, and Treat Tumors Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080556 Tissue-specific Gene Delivery Via Nanoparticle Coating Biomaterials. Feb, 2010 | Pubmed ID: 19850333 SERS-Coded Gold Nanorods As a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating Advanced Materials (Deerfield Beach, Fla.). Apr, 2009 | Pubmed ID: 20174478 Silicon Nanoparticles As Hyperpolarized Magnetic Resonance Imaging Agents ACS Nano. Dec, 2009 | Pubmed ID: 19950973 Microenvironmental Regulation of the Sinusoidal Endothelial Cell Phenotype in Vitro Hepatology (Baltimore, Md.). Sep, 2009 | Pubmed ID: 19585615 Computationally Guided Photothermal Tumor Therapy Using Long-circulating Gold Nanorod Antennas Cancer Research. May, 2009 | Pubmed ID: 19366797 Systematic Surface Engineering of Magnetic Nanoworms for in Vivo Tumor Targeting Small (Weinheim an Der Bergstrasse, Germany). Mar, 2009 | Pubmed ID: 19263431 Biodegradable Luminescent Porous Silicon Nanoparticles for in Vivo Applications Nature Materials. Apr, 2009 | Pubmed ID: 19234444 Statistical Dynamics of Flowing Red Blood Cells by Morphological Image Processing PLoS Computational Biology. Feb, 2009 | Pubmed ID: 19214200 Modulation of Hepatocyte Phenotype in Vitro Via Chemomechanical Tuning of Polyelectrolyte Multilayers Biomaterials. Feb, 2009 | Pubmed ID: 19046762 Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging Advanced Materials (Deerfield Beach, Fla.). May, 2008 | Pubmed ID: 21687830 Micellar Hybrid Nanoparticles for Simultaneous Magnetofluorescent Imaging and Drug Delivery Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18696519 Protease-triggered Unveiling of Bioactive Nanoparticles Small (Weinheim an Der Bergstrasse, Germany). Sep, 2008 | Pubmed ID: 18690639 T-cadherin Modulates Hepatocyte Functions in Vitro FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2008 | Pubmed ID: 18635739 Microscale Culture of Human Liver Cells for Drug Development Nature Biotechnology. Jan, 2008 | Pubmed ID: 18026090 High-throughput Analysis of Signals Regulating Stem Cell Fate and Function Current Opinion in Chemical Biology. Aug, 2007 | Pubmed ID: 17656147 Multiphase Electropatterning of Cells and Biomaterials Lab on a Chip. Jun, 2007 | Pubmed ID: 17538711 Micromechanical Control of Cell-cell Interactions Proceedings of the National Academy of Sciences of the United States of America. Apr, 2007 | Pubmed ID: 17389399 Microscale Control of Cell Contact and Spacing Via Three-component Surface Patterning Langmuir : the ACS Journal of Surfaces and Colloids. Apr, 2007 | Pubmed ID: 17243746 Assessment of Hepatocellular Function Within PEG Hydrogels Biomaterials. Jan, 2007 | Pubmed ID: 16979755 Engineering Tissues for in Vitro Applications Current Opinion in Biotechnology. Oct, 2006 | Pubmed ID: 16978857 Local Heating of Discrete Droplets Using Magnetic Porous Silicon-based Photonic Crystals Journal of the American Chemical Society. Jun, 2006 | Pubmed ID: 16771508 Proteolytic Actuation of Nanoparticle Self-assembly Angewandte Chemie (International Ed. in English). May, 2006 | Pubmed ID: 16642514 Quantum Dots to Monitor RNAi Delivery and Improve Gene Silencing Nucleic Acids Research. 2005 | Pubmed ID: 16352864 Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging Audrey E. Van Heest1, Feiyang Deng1, Renee T. Zhao2, Nour Saida Harzallah2,3, Heather E. Fleming3,4, Sangeeta N. Bhatia2,3,4,5,6,7,8, Liangliang Hao1,2,3 1Department of Biomedical Engineering, Boston University, 2Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 4Howard Hughes Medical Institute, 5Broad Institute of Massachusetts Institute of Technology and Harvard, 6Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 8Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School JoVE 66189 Bioengineering
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging Audrey E. Van Heest1, Feiyang Deng1, Renee T. Zhao2, Nour Saida Harzallah2,3, Heather E. Fleming3,4, Sangeeta N. Bhatia2,3,4,5,6,7,8, Liangliang Hao1,2,3 1Department of Biomedical Engineering, Boston University, 2Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 4Howard Hughes Medical Institute, 5Broad Institute of Massachusetts Institute of Technology and Harvard, 6Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 8Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School JoVE 66189 Bioengineering