Sean S. Davies Division of Clinical Pharmacology, Department of Medicine Vanderbilt University Medical Center Biography Publications Institution JoVE Articles Sean S. Davies has not added a biography. If you are Sean S. Davies and would like to personalize this page please email our Author Liaison for assistance. Publications Kidney Injury-mediated Disruption of Intestinal Lymphatics Involves Dicarbonyl-modified Lipoproteins Kidney International. Jun, 2021 | Pubmed ID: 34102217 Sodium Activates Human Monocytes Via the NADPH Oxidase and Isolevuglandin Formation Cardiovascular Research. Apr, 2021 | Pubmed ID: 33038226 Engineering the Gut Microbiota to Treat Chronic Diseases Applied Microbiology and Biotechnology. Sep, 2020 | Pubmed ID: 32696297 Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity Nutrients. Jun, 2020 | Pubmed ID: 32629758 Pro-inflammatory HDL in Women with Obesity and Nonalcoholic Steatohepatitis Obesity Research & Clinical Practice. Jul - Aug, 2020 | Pubmed ID: 32595023 Progressively Decreasing Plasma High-density Lipoprotein Cholesterol Levels Preceding Diagnosis of Smoldering Myeloma Journal of Clinical Lipidology. May - Jun, 2020 | Pubmed ID: 32376310 Symmetrically Substituted Dichlorophenes Inhibit -acyl-phosphatidylethanolamine Phospholipase D The Journal of Biological Chemistry. 05, 2020 | Pubmed ID: 32284327 Modified Sites and Functional Consequences of 4-oxo-2-nonenal Adducts in HDL That Are Elevated in Familial Hypercholesterolemia The Journal of Biological Chemistry. 12, 2019 | Pubmed ID: 31666337 Arachidonic Acid Kills Staphylococcus Aureus Through a Lipid Peroxidation Mechanism MBio. 10, 2019 | Pubmed ID: 31575763 Two-week Administration of Engineered Escherichia Coli Establishes Persistent Resistance to Diet-induced Obesity Even Without Antibiotic Pre-treatment Applied Microbiology and Biotechnology. Aug, 2019 | Pubmed ID: 31203417 Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor Mice Improves Indices of Cardiometabolic Disease Scientific Reports. 01, 2019 | Pubmed ID: 30674978 Simplified LC/MS Assay for the Measurement of Isolevuglandin Protein Adducts in Plasma and Tissue Samples Analytical Biochemistry. 02, 2019 | Pubmed ID: 30458125 Isolevuglandins and Cardiovascular Disease Prostaglandins & Other Lipid Mediators. 11, 2018 | Pubmed ID: 30296489 Modification by Isolevuglandins, Highly Reactive γ-ketoaldehydes, Deleteriously Alters High-density Lipoprotein Structure and Function The Journal of Biological Chemistry. 06, 2018 | Pubmed ID: 29712723 Leptogenic Effects of NAPE Require Activity of NAPE-hydrolyzing Phospholipase D Journal of Lipid Research. 08, 2017 | Pubmed ID: 28596183 Dendritic Cells and Isolevuglandins in Immunity, Inflammation, and Hypertension American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2017 | Pubmed ID: 27986660 Net Cholesterol Efflux Capacity of HDL Enriched Serum and Coronary Atherosclerosis in Rheumatoid Arthritis IJC Metabolic & Endocrine. Dec, 2016 | Pubmed ID: 28243578 Accumulation of Isolevuglandin-modified Protein in Normal and Fibrotic Lung Scientific Reports. 04, 2016 | Pubmed ID: 27118599 Microbial Metabolism of Dietary Components to Bioactive Metabolites: Opportunities for New Therapeutic Interventions Genome Medicine. Apr, 2016 | Pubmed ID: 27102537 Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis Arthritis & Rheumatology (Hoboken, N.J.). Sep, 2016 | Pubmed ID: 26991245 Immune Activation Caused by Vascular Oxidation Promotes Fibrosis and Hypertension The Journal of Clinical Investigation. Jan, 2016 | Pubmed ID: 26595812 DC Isoketal-modified Proteins Activate T Cells and Promote Hypertension The Journal of Clinical Investigation. Oct, 2014 | Pubmed ID: 25244096 Lipid Peroxidation Generates Biologically Active Phospholipids Including Oxidatively N-modified Phospholipids Chemistry and Physics of Lipids. Jul, 2014 | Pubmed ID: 24704586 Treatment with a γ-ketoaldehyde Scavenger Prevents Working Memory Deficits in HApoE4 Mice Journal of Alzheimer's Disease : JAD. 2011 | Pubmed ID: 21709376 F2-isoprostanes As an Indicator and Risk Factor for Coronary Heart Disease Free Radical Biology & Medicine. Mar, 2011 | Pubmed ID: 21126576 Ischemia/reperfusion Unveils Impaired Capacity of Older Adults to Restrain Oxidative Insult Free Radical Biology & Medicine. Oct, 2009 | Pubmed ID: 19596063 Amitriptyline Activates Cardiac Ryanodine Channels and Causes Spontaneous Sarcoplasmic Reticulum Calcium Release Molecular Pharmacology. Jan, 2009 | Pubmed ID: 18845675 Pyridoxamine Analogues Scavenge Lipid-derived Gamma-ketoaldehydes and Protect Against H2O2-mediated Cytotoxicity Biochemistry. Dec, 2006 | Pubmed ID: 17176098 Quantification of Dinor, Dihydro Metabolites of F2-isoprostanes in Urine by Liquid Chromatography/tandem Mass Spectrometry Analytical Biochemistry. Jan, 2006 | Pubmed ID: 16309621 Localization of Isoketal Adducts in Vivo Using a Single-chain Antibody Free Radical Biology & Medicine. May, 2004 | Pubmed ID: 15082070 Isoketals: Highly Reactive Gamma-ketoaldehydes Formed from the H2-isoprostane Pathway Chemistry and Physics of Lipids. Mar, 2004 | Pubmed ID: 15037155 Hydrolysis of Bimatoprost (Lumigan) to Its Free Acid by Ocular Tissue in Vitro Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Feb, 2003 | Pubmed ID: 12648303 Direkter Nachweis von Isolevuglandinen in Geweben mittels eines D11 scFv-alkalischen Phosphatase-Fusionsproteins und Immunfluoreszenz Cassandra Warden*1, Alan J. Simmons*2, Lejla Pasic3, Ashley Pitzer4,6, Sean S. Davies4, Justin H. Layer5, Raymond L. Mernaugh3, Annet Kirabo4,6 1Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2Department of Cell and Developmental Biology, Vanderbilt University, 3Department of Biochemistry, Vanderbilt University, 4Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 5Division of Hematology and Oncology, Indiana University School of Medicine, 6Department of Molecular Physiology and Biophysics, Vanderbilt University JoVE 62603 Biology
Direkter Nachweis von Isolevuglandinen in Geweben mittels eines D11 scFv-alkalischen Phosphatase-Fusionsproteins und Immunfluoreszenz Cassandra Warden*1, Alan J. Simmons*2, Lejla Pasic3, Ashley Pitzer4,6, Sean S. Davies4, Justin H. Layer5, Raymond L. Mernaugh3, Annet Kirabo4,6 1Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2Department of Cell and Developmental Biology, Vanderbilt University, 3Department of Biochemistry, Vanderbilt University, 4Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 5Division of Hematology and Oncology, Indiana University School of Medicine, 6Department of Molecular Physiology and Biophysics, Vanderbilt University JoVE 62603 Biology