Seth Blackshaw Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Seth Blackshaw has not added a biography. If you are Seth Blackshaw and would like to personalize this page please email our Author Liaison for assistance. Publications Midkine is Neuroprotective and Influences Glial Reactivity and the Formation of Müller Glia-derived Progenitor Cells in Chick and Mouse Retinas Glia. Feb, 2021 | Pubmed ID: 33569849 Temperature and Species-dependent Regulation of Browning in Retrobulbar Fat Scientific Reports. Feb, 2021 | Pubmed ID: 33542375 Turning Lead into Gold: Reprogramming Retinal Cells to Cure Blindness The Journal of Clinical Investigation. Feb, 2021 | Pubmed ID: 33529169 Gene Regulatory Networks Controlling Differentiation, Survival, and Diversification of Hypothalamic Lhx6-expressing GABAergic Neurons Communications Biology. Jan, 2021 | Pubmed ID: 33479483 Gene Regulatory Networks Controlling Vertebrate Retinal Regeneration Science (New York, N.Y.). 11, 2020 | Pubmed ID: 33004674 Zeb2 Regulates the Balance Between Retinal Interneurons and Müller Glia by Inhibition of BMP-Smad Signaling Developmental Biology. 12, 2020 | Pubmed ID: 32950463 The Cellular and Molecular Landscape of Hypothalamic Patterning and Differentiation from Embryonic to Late Postnatal Development Nature Communications. 08, 2020 | Pubmed ID: 32868762 Epigenetic Hallmarks of Age-related Macular Degeneration Are Recapitulated in a Photosensitive Mouse Model Human Molecular Genetics. Aug, 2020 | Pubmed ID: 32691052 Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development Developmental Cell. 05, 2020 | Pubmed ID: 32386599 NF-κB Signaling Regulates the Formation of Proliferating Müller Glia-derived Progenitor Cells in the Avian Retina Development (Cambridge, England). 05, 2020 | Pubmed ID: 32291273 Tanycyte Ablation in the Arcuate Nucleus and Median Eminence Increases Obesity Susceptibility by Increasing Body Fat Content in Male Mice Glia. Oct, 2020 | Pubmed ID: 32173924 ASCOT Identifies Key Regulators of Neuronal Subtype-specific Splicing Nature Communications. 01, 2020 | Pubmed ID: 31919425 Clarin-1 Expression in Adult Mouse and Human Retina Highlights a Role of Müller Glia in Usher Syndrome The Journal of Pathology. 02, 2020 | Pubmed ID: 31625146 Photic Generation of 11--retinal in Bovine Retinal Pigment Epithelium The Journal of Biological Chemistry. 12, 2019 | Pubmed ID: 31694912 PanoView: An Iterative Clustering Method for Single-cell RNA Sequencing Data PLoS Computational Biology. 08, 2019 | Pubmed ID: 31469823 Global Analysis of Intercellular Homeodomain Protein Transfer Cell Reports. 07, 2019 | Pubmed ID: 31315049 Matrix-metalloproteinase Expression and Gelatinase Activity in the Avian Retina and Their Influence on Müller Glia Proliferation Experimental Neurology. 10, 2019 | Pubmed ID: 31251936 Reactive Microglia and IL1β/IL-1R1-signaling Mediate Neuroprotection in Excitotoxin-damaged Mouse Retina Journal of Neuroinflammation. Jun, 2019 | Pubmed ID: 31170999 Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors As Regulating Mitotic Exit and Late-Born Cell Specification Neuron. 06, 2019 | Pubmed ID: 31128945 The Selective Estrogen Receptor Modulator Raloxifene Mitigates the Effect of All--retinal Toxicity in Photoreceptor Degeneration The Journal of Biological Chemistry. 06, 2019 | Pubmed ID: 31073029 Epigenomic Profiling of Retinal Progenitors Reveals LHX2 is Required for Developmental Regulation of Open Chromatin Communications Biology. 2019 | Pubmed ID: 31044167 Conditional Deletion of Des1 in the Mouse Retina Does Not Impair the Visual Cycle in Cones FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 04, 2019 | Pubmed ID: 30645148 Disruption of Stromal Hedgehog Signaling Initiates RNF5-mediated Proteasomal Degradation of PTEN and Accelerates Pancreatic Tumor Growth Life Science Alliance. Oct, 2018 | Pubmed ID: 30456390 Canonical Wnt Signaling Regulates Patterning, Differentiation and Nucleogenesis in Mouse Hypothalamus and Prethalamus Developmental Biology. 10, 2018 | Pubmed ID: 30063881 Asymmetric Vasopressin Signaling Spatially Organizes the Master Circadian Clock The Journal of Comparative Neurology. 09, 2018 | Pubmed ID: 29931690 Antibody Specificity Profiling Using Protein Microarrays Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29714021 Foxd1 is Required for Terminal Differentiation of Anterior Hypothalamic Neuronal Subtypes Developmental Biology. 07, 2018 | Pubmed ID: 29679559 Ldb1- and Rnf12-dependent Regulation of Lhx2 Controls the Relative Balance Between Neurogenesis and Gliogenesis in the Retina Development (Cambridge, England). 04, 2018 | Pubmed ID: 29650591 A Toolbox of Immunoprecipitation-grade Monoclonal Antibodies to Human Transcription Factors Nature Methods. 05, 2018 | Pubmed ID: 29638227 ATAC-Seq Analysis Reveals a Widespread Decrease of Chromatin Accessibility in Age-related Macular Degeneration Nature Communications. 04, 2018 | Pubmed ID: 29636475 Regulation and Function of Neurogenesis in the Adult Mammalian Hypothalamus Progress in Neurobiology. 11, 2018 | Pubmed ID: 29631023 Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk Between SUMOylation and Phosphorylation Promotes Cell Migration Molecular & Cellular Proteomics : MCP. 05, 2018 | Pubmed ID: 29438996 In Vivo Electroporation of Developing Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29188509 Pax6 is Essential for the Generation of Late-born Retinal Neurons and for Inhibition of Photoreceptor-fate During Late Stages of Retinogenesis Developmental Biology. 12, 2017 | Pubmed ID: 28993200 Lhx6-positive GABA-releasing Neurons of the Zona Incerta Promote Sleep Nature. 08, 2017 | Pubmed ID: 28847002 Understanding the Role of LncRNAs in Nervous System Development Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28815543 Assessing the Model Transferability for Prediction of Transcription Factor Binding Sites Based on Chromatin Accessibility BMC Bioinformatics. Jul, 2017 | Pubmed ID: 28750606 Global Analysis of SUMO-Binding Proteins Identifies SUMOylation As a Key Regulator of the INO80 Chromatin Remodeling Complex Molecular & Cellular Proteomics : MCP. 05, 2017 | Pubmed ID: 28254775 The Long Non-coding RNA NEAT1 is Responsive to Neuronal Activity and is Associated with Hyperexcitability States Scientific Reports. 01, 2017 | Pubmed ID: 28054653 An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks Current Biology : CB. Jan, 2017 | Pubmed ID: 28017605 A Nuclease That Mediates Cell Death Induced by DNA Damage and Poly(ADP-ribose) Polymerase-1 Science (New York, N.Y.). 10, 2016 | Pubmed ID: 27846469 The Stage-dependent Roles of Ldb1 and Functional Redundancy with Ldb2 in Mammalian Retinogenesis Development (Cambridge, England). 11, 2016 | Pubmed ID: 27697904 The NIH Protein Capture Reagents Program (PCRP): a Standardized Protein Affinity Reagent Toolbox Nature Methods. 09, 2016 | Pubmed ID: 27684578 Control of Lens Development by Lhx2-regulated Neuroretinal FGFs Development (Cambridge, England). 11, 2016 | Pubmed ID: 27633990 Multiple Intrinsic Factors Act in Concert with Lhx2 to Direct Retinal Gliogenesis Scientific Reports. 09, 2016 | Pubmed ID: 27605455 Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier Genetics. 06, 2016 | Pubmed ID: 27029737 The Nutrient Sensor OGT in PVN Neurons Regulates Feeding Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 26989246 Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2016 | Pubmed ID: 26911688 EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation Sleep. Mar, 2016 | Pubmed ID: 26612390 Constructing the Suprachiasmatic Nucleus: a Watchmaker's Perspective on the Central Clockworks Frontiers in Systems Neuroscience. 2015 | Pubmed ID: 26005407 Identification of SUMO E3 Ligase-specific Substrates Using the HuProt Human Proteome Microarray Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25820740 Patterning, Specification, and Differentiation in the Developing Hypothalamus Wiley Interdisciplinary Reviews. Developmental Biology. Sep-Oct, 2015 | Pubmed ID: 25820448 A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors Neuron. Feb, 2015 | Pubmed ID: 25654255 The LIM Homeodomain Factor Lhx2 is Required for Hypothalamic Tanycyte Specification and Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2014 | Pubmed ID: 25505333 Notch3 Interactome Analysis Identified WWP2 As a Negative Regulator of Notch3 Signaling in Ovarian Cancer PLoS Genetics. Oct, 2014 | Pubmed ID: 25356737 Serine Racemase Regulated by Binding to Stargazin and PSD-95: Potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (NMDA-AMPA) Glutamate Neurotransmission Cross-talk The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25164819 Characterization of the SUMO-binding Activity of the Myeloproliferative and Mental Retardation (MYM)-type Zinc Fingers in ZNF261 and ZNF198 PloS One. 2014 | Pubmed ID: 25133527 Dietary and Sex-specific Factors Regulate Hypothalamic Neurogenesis in Young Adult Mice Frontiers in Neuroscience. 2014 | Pubmed ID: 24982613 Long Non-coding RNA-dependent Transcriptional Regulation in Neuronal Development and Disease Frontiers in Genetics. 2014 | Pubmed ID: 24936207 Lhx1 Controls Terminal Differentiation and Circadian Function of the Suprachiasmatic Nucleus Cell Reports. May, 2014 | Pubmed ID: 24767996 Rax-CreERT2 Knock-in Mice: a Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus PloS One. 2014 | Pubmed ID: 24699247 Feed Your Head: Neurodevelopmental Control of Feeding and Metabolism Annual Review of Physiology. 2014 | Pubmed ID: 24274739 Stage-specific Inhibition of TrkB Activity Leads to Long-lasting and Sexually Dimorphic Effects on Body Weight and Hypothalamic Gene Expression PloS One. 2013 | Pubmed ID: 24312242 RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention Neuron. Oct, 2013 | Pubmed ID: 24139042 Protein Microarray Characterization of the S-nitrosoproteome Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 24105792 Estrogen-related Receptor Beta Deficiency Alters Body Composition and Response to Restraint Stress BMC Physiology. Sep, 2013 | Pubmed ID: 24053666 Rax Regulates Hypothalamic Tanycyte Differentiation and Barrier Function in Mice The Journal of Comparative Neurology. Aug, 2013 | Pubmed ID: 23939786 Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 23824909 LHX2 is Necessary for the Maintenance of Optic Identity and for the Progression of Optic Morphogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2013 | Pubmed ID: 23595746 Identification of Hypothalamic Neuron-derived Neurotrophic Factor As a Novel Factor Modulating Appetite American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2013 | Pubmed ID: 23576617 Construction of Human Activity-based Phosphorylation Networks Molecular Systems Biology. 2013 | Pubmed ID: 23549483 Estrogen-related Receptor β Deletion Modulates Whole-body Energy Balance Via Estrogen-related Receptor γ and Attenuates Neuropeptide Y Gene Expression The European Journal of Neuroscience. Apr, 2013 | Pubmed ID: 23360481 High-throughput RNA in Situ Hybridization in Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23150371 Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Dec, 2012 | Pubmed ID: 22867732 WITHDRAWN: Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Jul, 2012 | Pubmed ID: 22814121 Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays Molecular & Cellular Proteomics : MCP. Sep, 2012 | Pubmed ID: 22647870 Tanycytes of the Hypothalamic Median Eminence Form a Diet-responsive Neurogenic Niche Nature Neuroscience. May, 2012 | Pubmed ID: 22446882 Botch Promotes Neurogenesis by Antagonizing Notch Developmental Cell. Apr, 2012 | Pubmed ID: 22445366 Injury-independent Induction of Reactive Gliosis in Retina by Loss of Function of the LIM Homeodomain Transcription Factor Lhx2 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22393024 使用人类蛋白质组芯片的 Monospecific 单克隆抗体的快速鉴定。 Molecular & Cellular Proteomics : MCP. Feb, 2012 | Pubmed ID: 22307071 CK2 的磷酸化及规管措施 O GlcNAcylation 揭示的半合成。 Nature Chemical Biology. 2012 | Pubmed ID: 22267120 酵母单杂交检测方法基因为中心的人类基因调控网络映射。 Nature Methods. Dec, 2011 | Pubmed ID: 22037702 长非编码 RNA Six3OS 行为在跨通过调节 Six3 活动调节视网膜的发育。 Neural Development. 2011 | Pubmed ID: 21936910 我们包含众多: 至于脸视网膜母细胞瘤。 Cancer Cell. Aug, 2011 | Pubmed ID: 21840479 Spalt 家族转录因子 Sall3 规管锥感光细胞和视网膜水平 Interneurons 的发展。 Development (Cambridge, England). Jun, 2011 | Pubmed ID: 21558380 蛋白质微阵列的 DNA-蛋白质相互作用的表征。 Cold Spring Harbor Protocols. May, 2011 | Pubmed ID: 21536762 DNA-蛋白质相互作用的系统表征。 Cellular and Molecular Life Sciences : CMLS. May, 2011 | Pubmed ID: 21207099 在早期的产后鼠标丘脑区域特异性基因表达。 The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192083 动态时空基因在小鼠胚胎丘脑的表达。 The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192082 功能性蛋白芯片技术。 Wiley Interdisciplinary Reviews. Systems Biology and Medicine. May-Jun, 2011 | Pubmed ID: 20872749 控制发展的丘脑和下丘脑的分子途径: 从神经电路形成规范。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21068293 依赖于 Pias3 的 SUMOylation 控制哺乳动物锥感光器分化。 Nature Neuroscience. Sep, 2010 | Pubmed ID: 20729845 鼠脑解剖特性的三维扩散张量显微成像。 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2010 | Pubmed ID: 20577980 孤儿核激素受体 ERRbeta 控制杆感光器生存。 Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534447 长非编码 RNA RNCR2 指示鼠标视网膜细胞规范。 BMC Developmental Biology. 2010 | Pubmed ID: 20459797 小鼠下丘脑发育基因组图集。 Nature Neuroscience. Jun, 2010 | Pubmed ID: 20436479 HPDI: 实验人类 DNA-蛋白质相互作用的数据库。 Bioinformatics (Oxford, England). Jan, 2010 | Pubmed ID: 19900953 脊椎动物的视网膜和下丘脑发育。 Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Nov-Dec, 2009 | Pubmed ID: 20836003 分析人类 DNA-蛋白质 Interactome 的干扰素信号转导转录阻遏物作为揭示 ERK2。 Cell. Oct, 2009 | Pubmed ID: 19879846 Muscleblind 样 2: 由肾上腺素能营机制控制哺乳动物的松果腺中的昼夜节律性表达。 Journal of Neurochemistry. Jul, 2009 | Pubmed ID: 19457059 新消息中的意义: 非编码 Rna 和在视网膜发育中的作用。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2009 | Pubmed ID: 19191220 Pias3 依赖 SUMOylation 指示杆感光器发展。 Neuron. Jan, 2009 | Pubmed ID: 19186166 D-天冬氨酸和 D-天冬氨酸氧化酶在鼠标视网膜显示选择性和发育动态的本地化。 Experimental Eye Research. Apr, 2008 | Pubmed ID: 18314103 (SAGE) 基因表达系列分析: 实验方法及数据分析。 Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [et Al.]. Apr, 2007 | Pubmed ID: 18428405 (SAGE) 基因表达系列分析: 实验方法及数据分析。 Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. Oct, 2007 | Pubmed ID: 18265400 在缺乏为 D-天冬氨酸氧化酶基因的雄性小鼠的行为改变。 Behavioural Brain Research. Aug, 2006 | Pubmed ID: 16725213 D-天冬氨酸,规管黑皮形成和函数: D-天冬氨酸氧化酶缺陷小鼠的行为变化。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16525061 蛋氨酸 Adenosyltransferase: 肾上腺素能营机制调节松果体的表达式中的每日节律。 The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15504733 SAGE 数据使用泊方法的聚类分析。 Genome Biology. 2004 | Pubmed ID: 15239836 鼠视网膜发育的基因组分析。 PLoS Biology. Sep, 2004 | Pubmed ID: 15226823 MicroSAGE 是高度代表性和可重现,但揭示了类似组织从获得的样本之间基因表达的主要差异。 Genome Biology. 2003 | Pubmed ID: 12620102 知道他们地方的干细胞。 Nature Neuroscience. Dec, 2002 | Pubmed ID: 12447376 继承的失明与细胞周期调节蛋白 NUB1 相关的蛋白 AIPL1 进行交互。 Human Molecular Genetics. Oct, 2002 | Pubmed ID: 12374762 肌苷磷酸脱氢酶 1 基因 (IMPDH1) 基因突变导致 RP10 形式的常染色体显性遗传视网膜色素变性。 Human Molecular Genetics. Mar, 2002 | Pubmed ID: 11875050 将基因组学技术应用于神经发展。 Current Opinion in Neurobiology. Feb, 2002 | Pubmed ID: 11861173 配置文件的人周边视网膜、 黄斑和通过串行分析基因表达 (SAGE) 确定的视网膜色素上皮细胞中表达的基因。 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11756676 Poly(ADP-ribosyl)ation Basally Activated by DNA Strand Breaks Reflects Glutamate-nitric Oxide Neurotransmission Proceedings of the National Academy of Sciences of the United States of America. Feb, 2000 | Pubmed ID: 10677544 A Novel Neuron-enriched Homolog of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 1999 | Pubmed ID: 10414974 Poly(ADP-ribose) Polymerase-deficient Mice Are Protected from Streptozotocin-induced Diabetes Proceedings of the National Academy of Sciences of the United States of America. Mar, 1999 | Pubmed ID: 10077636 The 13-kD FK506 Binding Protein, FKBP13, Interacts with a Novel Homologue of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Cell Biology. Apr, 1998 | Pubmed ID: 9531554 Parapinopsin, a Novel Catfish Opsin Localized to the Parapineal Organ, Defines a New Gene Family The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334384 Developmental Expression Pattern of Phototransduction Components in Mammalian Pineal Implies a Light-sensing Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334383 The Development of Excitatory Synapses in Cultured Spinal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 1997 | Pubmed ID: 9295380 Neuronal Nitric Oxide Synthase Alternatively Spliced Forms: Prominent Functional Localizations in the Brain Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997 | Pubmed ID: 9096405 使用 scRNA-Seq 和 scATAC-Seq 对视网膜基因表达和染色质可及性进行多重分析 Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience 成人下丘脑神经发生局灶性放射性抑制功能审讯 Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience 在发展中国家小鼠视网膜体内电穿孔 Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience
使用 scRNA-Seq 和 scATAC-Seq 对视网膜基因表达和染色质可及性进行多重分析 Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience
成人下丘脑神经发生局灶性放射性抑制功能审讯 Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience
在发展中国家小鼠视网膜体内电穿孔 Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience