Simon A. Gayther Department of Preventive Medicine University of Southern California Biography Publications Institution JoVE Articles Simon A. Gayther has not added a biography. If you are Simon A. Gayther and would like to personalize this page please email our Author Liaison for assistance. Publications Genome-Wide Association Study for Ovarian Cancer Susceptibility Using Pooled DNA Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies. Jul, 2012 | Pubmed ID: 22794196 Inherited Risk of Ovarian Cancer and the Implications for Screening International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. May, 2012 | Pubmed ID: 22543911 Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures That Predict Breast Cancer Risk Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2012 | Pubmed ID: 22454379 Association Between Endometriosis and Risk of Histological Subtypes of Ovarian Cancer: a Pooled Analysis of Case-control Studies The Lancet Oncology. Apr, 2012 | Pubmed ID: 22361336 Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Apr, 2012 | Pubmed ID: 22351618 Common Variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 Are Associated with Breast Cancer Risk for BRCA1 And/or BRCA2 Mutation Carriers Breast Cancer Research : BCR. Feb, 2012 | Pubmed ID: 22348646 Role of Common Genetic Variants in Ovarian Cancer Susceptibility and Outcome: Progress to Date from the Ovarian Cancer Association Consortium (OCAC) Journal of Internal Medicine. Feb, 2012 | Pubmed ID: 22309431 Gene Set Analysis of Survival Following Ovarian Cancer Implicates Macrolide Binding and Intracellular Signaling Genes Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Mar, 2012 | Pubmed ID: 22302016 Ovarian Cancer Risk Associated with Inherited Inflammation-related Variants Cancer Research. Mar, 2012 | Pubmed ID: 22282663 Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer JAMA : the Journal of the American Medical Association. Jan, 2012 | Pubmed ID: 22274685 Ovarian Cancer Susceptibility Alleles and Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers Human Mutation. Jan, 2012 | Pubmed ID: 22253144 Pathology of Breast and Ovarian Cancers Among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2012 | Pubmed ID: 22144499 Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers PloS One. 2011 | Pubmed ID: 21949822 Common Variants of the BRCA1 Wild-type Allele Modify the Risk of Breast Cancer in BRCA1 Mutation Carriers Human Molecular Genetics. Dec, 2011 | Pubmed ID: 21890493 Modelling Genetic and Clinical Heterogeneity in Epithelial Ovarian Cancers Carcinogenesis. Oct, 2011 | Pubmed ID: 21859834 Estrogen Receptor Beta Rs1271572 Polymorphism and Invasive Ovarian Carcinoma Risk: Pooled Analysis Within the Ovarian Cancer Association Consortium PloS One. 2011 | Pubmed ID: 21673961 Polymorphisms in Stromal Genes and Susceptibility to Serous Epithelial Ovarian Cancer: a Report from the Ovarian Cancer Association Consortium PloS One. 2011 | Pubmed ID: 21637745 MicroRNA Processing and Binding Site Polymorphisms Are Not Replicated in the Ovarian Cancer Association Consortium Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Aug, 2011 | Pubmed ID: 21636674 Principles for the Post-GWAS Functional Characterization of Cancer Risk Loci Nature Genetics. Jun, 2011 | Pubmed ID: 21614091 LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer Cancer Research. Jun, 2011 | Pubmed ID: 21482675 A Kallikrein 15 (KLK15) Single Nucleotide Polymorphism Located Close to a Novel Exon Shows Evidence of Association with Poor Ovarian Cancer Survival BMC Cancer. 2011 | Pubmed ID: 21457553 Genetic Variation in Insulin-like Growth Factor 2 May Play a Role in Ovarian Cancer Risk Human Molecular Genetics. Jun, 2011 | Pubmed ID: 21422097 Prostate Cancer Susceptibility Polymorphism Rs2660753 is Not Associated with Invasive Ovarian Cancer Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. May, 2011 | Pubmed ID: 21415361 The Role of KRAS Rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2011 | Pubmed ID: 21385923 Profiling Signatures of Ovarian Cancer Tumour Suppression Using 2D-DIGE and 2D-LC-MS/MS with Tandem Mass Tagging Journal of Proteomics. Apr, 2011 | Pubmed ID: 21237297 Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers Journal of the National Cancer Institute. Jan, 2011 | Pubmed ID: 21169536 Recruitment of Newly Diagnosed Ovarian Cancer Patients Proved Challenging in a Multicentre Biobanking Study Journal of Clinical Epidemiology. May, 2011 | Pubmed ID: 21074968 Progesterone Receptor Gene Polymorphisms and Risk of Endometriosis: Results from an International Collaborative Effort Fertility and Sterility. Jan, 2011 | Pubmed ID: 20719308 Common Alleles in Candidate Susceptibility Genes Associated with Risk and Development of Epithelial Ovarian Cancer International Journal of Cancer. Journal International Du Cancer. May, 2011 | Pubmed ID: 20635389 Vitamin D Receptor Rs2228570 Polymorphism and Invasive Ovarian Carcinoma Risk: Pooled Analysis in Five Studies Within the Ovarian Cancer Association Consortium International Journal of Cancer. Journal International Du Cancer. Feb, 2011 | Pubmed ID: 20473893 A Polymorphism in the GALNT2 Gene and Ovarian Cancer Risk in Four Population Based Case-control Studies International Journal of Molecular Epidemiology and Genetics. 2010 | Pubmed ID: 21532840 Cancer Stem Cells and Epithelial Ovarian Cancer Journal of Oncology. 2010 | Pubmed ID: 21318146 Common Variants at 19p13 Are Associated with Susceptibility to Ovarian Cancer Nature Genetics. Oct, 2010 | Pubmed ID: 20852633 A Genome-wide Association Study Identifies Susceptibility Loci for Ovarian Cancer at 2q31 and 8q24 Nature Genetics. Oct, 2010 | Pubmed ID: 20852632 A Locus on 19p13 Modifies Risk of Breast Cancer in BRCA1 Mutation Carriers and is Associated with Hormone Receptor-negative Breast Cancer in the General Population Nature Genetics. Oct, 2010 | Pubmed ID: 20852631 Vascular Endothelial Growth Factor Gene Polymorphisms and Ovarian Cancer Survival Gynecologic Oncology. Dec, 2010 | Pubmed ID: 20832104 Microcell-mediated Chromosome Transfer Identifies EPB41L3 As a Functional Suppressor of Epithelial Ovarian Cancers Neoplasia (New York, N.Y.). Jul, 2010 | Pubmed ID: 20651987 Evaluation of Candidate Stromal Epithelial Cross-talk Genes Identifies Association Between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility "hot-spot" PLoS Genetics. Jul, 2010 | Pubmed ID: 20628624 Genetic Variation in TYMS in the One-carbon Transfer Pathway is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2010 | Pubmed ID: 20570913 The Inherited Genetics of Ovarian and Endometrial Cancer Current Opinion in Genetics & Development. Jun, 2010 | Pubmed ID: 20456938 Senescent Fibroblasts Promote Neoplastic Transformation of Partially Transformed Ovarian Epithelial Cells in a Three-dimensional Model of Early Stage Ovarian Cancer Neoplasia (New York, N.Y.). Apr, 2010 | Pubmed ID: 20360942 Age-dependent DNA Methylation of Genes That Are Suppressed in Stem Cells is a Hallmark of Cancer Genome Research. Apr, 2010 | Pubmed ID: 20219944 Polymorphism in the GALNT1 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women: the Ovarian Cancer Association Consortium Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Feb, 2010 | Pubmed ID: 20142253 ESR1/SYNE1 Polymorphism and Invasive Epithelial Ovarian Cancer Risk: an Ovarian Cancer Association Consortium Study Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2010 | Pubmed ID: 20056644 An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer PloS One. 2009 | Pubmed ID: 20019873 Assessing the Usefulness of a Novel MRI-based Breast Density Estimation Algorithm in a Cohort of Women at High Genetic Risk of Breast Cancer: the UK MARIBS Study Breast Cancer Research : BCR. 2009 | Pubmed ID: 19903338 A Genome-wide Association Study Identifies a New Ovarian Cancer Susceptibility Locus on 9p22.2 Nature Genetics. Sep, 2009 | Pubmed ID: 19648919 Eligibility for Magnetic Resonance Imaging Screening in the United Kingdom: Effect of Strict Selection Criteria and Anonymous DNA Testing on Breast Cancer Incidence in the MARIBS Study Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2009 | Pubmed ID: 19567506 Association Between Common Germline Genetic Variation in 94 Candidate Genes or Regions and Risks of Invasive Epithelial Ovarian Cancer PloS One. 2009 | Pubmed ID: 19543528 The Contribution of BRCA1 and BRCA2 to Ovarian Cancer Molecular Oncology. Apr, 2009 | Pubmed ID: 19383375 Association Between Invasive Ovarian Cancer Susceptibility and 11 Best Candidate SNPs from Breast Cancer Genome-wide Association Study Human Molecular Genetics. Jun, 2009 | Pubmed ID: 19304784 Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer Cancer Research. Mar, 2009 | Pubmed ID: 19276375 Functional Complementation Studies Identify Candidate Genes and Common Genetic Variants Associated with Ovarian Cancer Survival Human Molecular Genetics. May, 2009 | Pubmed ID: 19270026 Risk of Ovarian Cancer in Women with First-degree Relatives with Cancer Acta Obstetricia Et Gynecologica Scandinavica. 2009 | Pubmed ID: 19266357 Candidate Gene Analysis Using Imputed Genotypes: Cell Cycle Single-nucleotide Polymorphisms and Ovarian Cancer Risk Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Mar, 2009 | Pubmed ID: 19258477 Ovarian Cancer: a Clinical Challenge That Needs Some Basic Answers PLoS Medicine. Feb, 2009 | Pubmed ID: 19192945 The Clonal Evolution of Metastases from Primary Serous Epithelial Ovarian Cancers International Journal of Cancer. Journal International Du Cancer. Apr, 2009 | Pubmed ID: 19123469 Chromosomes 6 and 18 Induce Neoplastic Suppression in Epithelial Ovarian Cancer Cells International Journal of Cancer. Journal International Du Cancer. Mar, 2009 | Pubmed ID: 19058220 Polymorphism in the IL18 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2008 | Pubmed ID: 19064572 Association Study of Prostate Cancer Susceptibility Variants with Risks of Invasive Ovarian, Breast, and Colorectal Cancer Cancer Research. Nov, 2008 | Pubmed ID: 18974127 Predicting Clinical Outcome in Patients Diagnosed with Synchronous Ovarian and Endometrial Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2008 | Pubmed ID: 18794095 The Effects of Common Genetic Variants in Oncogenes on Ovarian Cancer Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2008 | Pubmed ID: 18794094 Mismatch Repair Gene Polymorphisms and Survival in Invasive Ovarian Cancer Patients European Journal of Cancer (Oxford, England : 1990). Oct, 2008 | Pubmed ID: 18723338 Multiple Loci with Different Cancer Specificities Within the 8q24 Gene Desert Journal of the National Cancer Institute. Jul, 2008 | Pubmed ID: 18577746 BRCA1 and BRCA2 Mutation Prevalence and Clinical Characteristics of a Population-based Series of Ovarian Cancer Cases from Denmark Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2008 | Pubmed ID: 18559594 Consortium Analysis of 7 Candidate SNPs for Ovarian Cancer International Journal of Cancer. Journal International Du Cancer. Jul, 2008 | Pubmed ID: 18431743 A Suite of Perl Modules for Handling Microarray Data Bioinformatics (Oxford, England). Apr, 2008 | Pubmed ID: 18353790 A Perl Toolkit for LIMS Development Source Code for Biology and Medicine. 2008 | Pubmed ID: 18353174 Effects of Common Germ-line Genetic Variation in Cell Cycle Genes on Ovarian Cancer Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18281541 Association Between Single-nucleotide Polymorphisms in Hormone Metabolism and DNA Repair Genes and Epithelial Ovarian Cancer: Results from Two Australian Studies and an Additional Validation Set Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2007 | Pubmed ID: 18086758 Contribution of BRCA1 and BRCA2 Mutations to Inherited Ovarian Cancer Human Mutation. Dec, 2007 | Pubmed ID: 17688236 Tagging Single Nucleotide Polymorphisms in Cell Cycle Control Genes and Susceptibility to Invasive Epithelial Ovarian Cancer Cancer Research. Apr, 2007 | Pubmed ID: 17409409 Screening for the BRCA1-ins6kbEx13 Mutation: Potential for Misdiagnosis. Mutation in Brief #964. Online Human Mutation. May, 2007 | Pubmed ID: 17397054 Tagging Single Nucleotide Polymorphisms in the BRIP1 Gene and Susceptibility to Breast and Ovarian Cancer PloS One. 2007 | Pubmed ID: 17342202 Common Variants in RB1 Gene and Risk of Invasive Ovarian Cancer Cancer Research. Oct, 2006 | Pubmed ID: 17047088 Ovarian Cancer Aetiology: Facts and Fiction The Journal of Family Planning and Reproductive Health Care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists. Apr, 2006 | Pubmed ID: 16824296 Common Variants in Mismatch Repair Genes and Risk of Invasive Ovarian Cancer Carcinogenesis. Nov, 2006 | Pubmed ID: 16774946 A Molecular Genetic and Statistical Approach for the Diagnosis of Dual-site Cancers Journal of the National Cancer Institute. Oct, 2004 | Pubmed ID: 15467033 STK15 Polymorphisms and Association with Risk of Invasive Ovarian Cancer Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Oct, 2004 | Pubmed ID: 15466974 A Modified Medium That Significantly Improves the Growth of Human Normal Ovarian Surface Epithelial (OSE) Cells in Vitro Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2004 | Pubmed ID: 15077121 Histopathology, FIGO Stage, and BRCA Mutation Status of Ovarian Cancers from the Gilda Radner Familial Ovarian Cancer Registry International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Jan, 2004 | Pubmed ID: 14668547 BRCA1/2 Mutation Status Influences Somatic Genetic Progression in Inherited and Sporadic Epithelial Ovarian Cancer Cases Cancer Research. Jan, 2003 | Pubmed ID: 12543797 Two Percent of Men with Early-onset Prostate Cancer Harbor Germline Mutations in the BRCA2 Gene American Journal of Human Genetics. Jan, 2003 | Pubmed ID: 12474142 BRCA1 and BRCA2 Mutations in a Population-based Study of Male Breast Cancer Breast Cancer Research : BCR. 2002 | Pubmed ID: 11879560 Üç boyutlu heterotipik Kate Lawrenson1, Barbara Grun2, Simon A. Gayther1 1Department of Preventive Medicine, University of Southern California, 2Institute for Women's Health, University College London JoVE 4206 Medicine
Üç boyutlu heterotipik Kate Lawrenson1, Barbara Grun2, Simon A. Gayther1 1Department of Preventive Medicine, University of Southern California, 2Institute for Women's Health, University College London JoVE 4206 Medicine