Stefan W. Ryter Department of Medicine, Division of Pulmonary and Critical Care Medicine Brigham and Women's Hospital Biography Publications Institution JoVE Articles Stefan W. Ryter has not added a biography. If you are Stefan W. Ryter and would like to personalize this page please email our Author Liaison for assistance. Publications Autophagic Proteins: New Facets of the Oxygen Paradox Autophagy. Mar, 2012 | Pubmed ID: 22302001 Pretreatment with Carbon Monoxide Releasing Molecules Suppresses Hepcidin Expression During Inflammation and Endoplasmic Reticulum Stress Through Inhibition of the STAT3 and CREBH Pathways Blood. Jan, 2012 | Pubmed ID: 22262759 Statins and Pulmonary Fibrosis: The Potential Role of NLRP3 Inflammasome Activation American Journal of Respiratory and Critical Care Medicine. Jan, 2012 | Pubmed ID: 22246178 Heme Oxygenase-1/CO As Protective Mediators in Cigarette Smoke-Induced Lung Cell Injury and Chronic Obstructive Pulmonary Disease Current Pharmaceutical Biotechnology. Sep, 2012 | Pubmed ID: 22201606 Autophagy in Pulmonary Diseases Annual Review of Physiology. Mar, 2012 | Pubmed ID: 22035347 Autophagy in Inflammatory Diseases International Journal of Cell Biology. 2011 | Pubmed ID: 22190939 Carbon Monoxide Inhibits Fas Activating Antibody-induced Apoptosis in Endothelial Cells Medical Gas Research. 2011 | Pubmed ID: 22146483 Hyperoxia Induced LC3B Interacts with the Fas Apoptotic Pathway in Epithelial Cell Death American Journal of Respiratory Cell and Molecular Biology. Nov, 2011 | Pubmed ID: 22095627 Beclin 1 Deficiency is Associated with Increased Hypoxia-induced Angiogenesis Autophagy. Aug, 2011 | Pubmed ID: 21685724 Carbon Monoxide, a Reaction Product of Heme Oxygenase-1, Suppresses the Expression of C-reactive Protein by Endoplasmic Reticulum Stress Through Modulation of the Unfolded Protein Response Molecular Immunology. Sep, 2011 | Pubmed ID: 21640381 Carbon Monoxide Activates Autophagy Via Mitochondrial Reactive Oxygen Species Formation American Journal of Respiratory Cell and Molecular Biology. Oct, 2011 | Pubmed ID: 21441382 Deadly Triplex: Smoke, Autophagy and Apoptosis Autophagy. Apr, 2011 | Pubmed ID: 21200154 Autophagy Proteins Regulate Innate Immune Responses by Inhibiting the Release of Mitochondrial DNA Mediated by the NALP3 Inflammasome Nature Immunology. Mar, 2011 | Pubmed ID: 21151103 Autophagic Protein LC3B Confers Resistance Against Hypoxia-induced Pulmonary Hypertension American Journal of Respiratory and Critical Care Medicine. Mar, 2011 | Pubmed ID: 20889906 Special Issue on Carbon Monoxide and Exhaled Biomarkers in Human Disease Journal of Breath Research. Dec, 2010 | Pubmed ID: 21383483 Autophagy Protein Microtubule-associated Protein 1 Light Chain-3B (LC3B) Activates Extrinsic Apoptosis During Cigarette Smoke-induced Emphysema Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20956295 Autophagy in Cigarette Smoke-induced Chronic Obstructive Pulmonary Disease Expert Review of Respiratory Medicine. Oct, 2010 | Pubmed ID: 20923337 Evaluation of Inhaled Carbon Monoxide As an Anti-inflammatory Therapy in a Nonhuman Primate Model of Lung Inflammation American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2010 | Pubmed ID: 20729385 Heme Oxygenase-1/carbon Monoxide: Novel Therapeutic Strategies in Critical Care Medicine Current Drug Targets. Dec, 2010 | Pubmed ID: 20704552 Inhaled Hydrogen Sulfide Protects Against Ventilator-induced Lung Injury Anesthesiology. Jul, 2010 | Pubmed ID: 20574227 Autophagy in Vascular Disease Proceedings of the American Thoracic Society. Feb, 2010 | Pubmed ID: 20160147 Autophagy in the Lung Proceedings of the American Thoracic Society. Feb, 2010 | Pubmed ID: 20160144 Heme Oxygenase-1/carbon Monoxide: from Metabolism to Molecular Therapy American Journal of Respiratory Cell and Molecular Biology. Sep, 2009 | Pubmed ID: 19617398 Heme Oxygenase-1, a Critical Arbitrator of Cell Death Pathways in Lung Injury and Disease Free Radical Biology & Medicine. Jul, 2009 | Pubmed ID: 19362144 Carbon Monoxide Prevents Ventilator-induced Lung Injury Via Caveolin-1 Critical Care Medicine. May, 2009 | Pubmed ID: 19325477 The Heme Oxygenase-1/carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1 Journal of Immunology (Baltimore, Md. : 1950). Mar, 2009 | Pubmed ID: 19265160 Analyzing Autophagy in Clinical Tissues of Lung and Vascular Diseases Methods in Enzymology. 2009 | Pubmed ID: 19216908 Autophagy in Chronic Obstructive Pulmonary Disease: Homeostatic or Pathogenic Mechanism? Autophagy. Feb, 2009 | Pubmed ID: 19066468 Identifying Targets for COPD Treatment Through Gene Expression Analyses International Journal of Chronic Obstructive Pulmonary Disease. 2008 | Pubmed ID: 18990963 Egr-1 Regulates Autophagy in Cigarette Smoke-induced Chronic Obstructive Pulmonary Disease PloS One. 2008 | Pubmed ID: 18830406 Network Analysis of Temporal Effects of Intermittent and Sustained Hypoxia on Rat Lungs Physiological Genomics. Dec, 2008 | Pubmed ID: 18826996 Autophagic Proteins Regulate Cigarette Smoke-induced Apoptosis: Protective Role of Heme Oxygenase-1 Autophagy. Oct, 2008 | Pubmed ID: 18769149 Inducing Hypoxemia in Healthy Humans: a Method for Intermittently Lowering Arterial Blood Oxygenation During Physiological Studies Wilderness & Environmental Medicine. 2008 | Pubmed ID: 18715123 Carbon Monoxide Protects Against Ventilator-induced Lung Injury Via PPAR-gamma and Inhibition of Egr-1 American Journal of Respiratory and Critical Care Medicine. Jun, 2008 | Pubmed ID: 18356564 Protein Kinase C Alpha and Zeta Differentially Regulate Death-inducing Signaling Complex Formation in Cigarette Smoke Extract-induced Apoptosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18354190 Deletion of Caveolin-1 Protects Against Oxidative Lung Injury Via Up-regulation of Heme Oxygenase-1 American Journal of Respiratory Cell and Molecular Biology. Aug, 2008 | Pubmed ID: 18323531 Caveolin-1: a Critical Regulator of Pulmonary Vascular Architecture and Nitric Oxide Bioavailability in Pulmonary Hypertension American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2008 | Pubmed ID: 18296499 Mitogen-activated Protein Kinases Regulate Susceptibility to Ventilator-induced Lung Injury PloS One. 2008 | Pubmed ID: 18270588 Nitric Oxide-deficiency Regulates Hepatic Heme Oxygenase-1 Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Feb, 2008 | Pubmed ID: 17999922 Exhaled Carbon Monoxide As a Biomarker of Inflammatory Lung Disease Journal of Breath Research. Dec, 2007 | Pubmed ID: 21383438 Functional Significance of Apoptosis in Chronic Obstructive Pulmonary Disease COPD. Dec, 2007 | Pubmed ID: 18027162 Protective Functions of Heme Oxygenase-1 and Carbon Monoxide in the Respiratory System Antioxidants & Redox Signaling. Dec, 2007 | Pubmed ID: 17845132 Carbon Monoxide in Sepsis Antioxidants & Redox Signaling. Nov, 2007 | Pubmed ID: 17822362 Thioredoxin Catalyzes the Denitrosation of Low-molecular Mass and Protein S-nitrosothiols Biochemistry. Jul, 2007 | Pubmed ID: 17580965 FLIP Inhibits Endothelial Cell Apoptosis During Hyperoxia by Suppressing Bax Free Radical Biology & Medicine. May, 2007 | Pubmed ID: 17448907 Cytoprotective and Anti-inflammatory Actions of Carbon Monoxide in Organ Injury and Sepsis Models Novartis Foundation Symposium. 2007 | Pubmed ID: 17380794 Hemodynamic and Molecular Response to Intermittent Hypoxia (IH) Versus Continuous Hypoxia (CH) in Normal Humans Translational Research : the Journal of Laboratory and Clinical Medicine. Feb, 2007 | Pubmed ID: 17240318 Carbon Monoxide Protects Against Hyperoxia-induced Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Formation The Journal of Biological Chemistry. Jan, 2007 | Pubmed ID: 17135272 Mechanisms of Cell Death in Oxidative Stress Antioxidants & Redox Signaling. Jan, 2007 | Pubmed ID: 17115887 Mitochondrial Localization and Function of Heme Oxygenase-1 in Cigarette Smoke-induced Cell Death American Journal of Respiratory Cell and Molecular Biology. Apr, 2007 | Pubmed ID: 17079780 Carbon Monoxide and Bilirubin: Potential Therapies for Pulmonary/vascular Injury and Disease American Journal of Respiratory Cell and Molecular Biology. Feb, 2007 | Pubmed ID: 16980550 Carbon Monoxide Differentially Inhibits TLR Signaling Pathways by Regulating ROS-induced Trafficking of TLRs to Lipid Rafts The Journal of Experimental Medicine. Oct, 2006 | Pubmed ID: 17000866 Heme Oxygenase-1/carbon Monoxide: from Basic Science to Therapeutic Applications Physiological Reviews. Apr, 2006 | Pubmed ID: 16601269 Therapeutic Applications of Carbon Monoxide in Lung Disease Current Opinion in Pharmacology. Jun, 2006 | Pubmed ID: 16580257 CO As a Cellular Signaling Molecule Annual Review of Pharmacology and Toxicology. 2006 | Pubmed ID: 16402911 Heat Shock Protein-70 Mediates the Cytoprotective Effect of Carbon Monoxide: Involvement of P38 Beta MAPK and Heat Shock Factor-1 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2005 | Pubmed ID: 16081837 Caveolin-1 Expression by Means of P38beta Mitogen-activated Protein Kinase Mediates the Antiproliferative Effect of Carbon Monoxide Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16051704 FLIP Protects Against Hypoxia/reoxygenation-induced Endothelial Cell Apoptosis by Inhibiting Bax Activation Molecular and Cellular Biology. Jun, 2005 | Pubmed ID: 15899875 Heme Oxygenase-1: Redox Regulation of a Stress Protein in Lung and Cell Culture Models Antioxidants & Redox Signaling. Jan-Feb, 2005 | Pubmed ID: 15650398 Bcl-XL Disrupts Death-inducing Signal Complex Formation in Plasma Membrane Induced by Hypoxia/reoxygenation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2004 | Pubmed ID: 15576486 Caveolae Compartmentalization of Heme Oxygenase-1 in Endothelial Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2004 | Pubmed ID: 15226268 Carbon Monoxide: to Boldly Go Where NO Has Gone Before Science's STKE : Signal Transduction Knowledge Environment. Apr, 2004 | Pubmed ID: 15114002 Carbon Monoxide in Biology and Medicine BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Mar, 2004 | Pubmed ID: 14988928 Hepatocyte Growth Factor Protects Against Hypoxia/reoxygenation-induced Apoptosis in Endothelial Cells The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14625309 Analysis of Pulmonary Heme Oxygenase-1 and Nitric Oxide Synthase Alterations in Experimental Hepatopulmonary Syndrome Gastroenterology. Nov, 2003 | Pubmed ID: 14598260 Heme Oxygenase-1 and Carbon Monoxide in Pulmonary Medicine Respiratory Research. 2003 | Pubmed ID: 12964953 Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/bid Pathway The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12754217 Heme Oxygenase-1: Molecular Mechanisms of Gene Expression in Oxygen-related Stress Antioxidants & Redox Signaling. Aug, 2002 | Pubmed ID: 12230874 Mitogen Activated Protein Kinase (MAPK) Pathway Regulates Heme Oxygenase-1 Gene Expression by Hypoxia in Vascular Cells Antioxidants & Redox Signaling. Aug, 2002 | Pubmed ID: 12230870 Heme Oxygenase/carbon Monoxide Signaling Pathways: Regulation and Functional Significance Molecular and Cellular Biochemistry. May-Jun, 2002 | Pubmed ID: 12162441 Cecal ligatie en punctie-geïnduceerde Sepsis als een model om Autophagy studie bij muizen Ilias I. Siempos1,3, Hilaire C. Lam1, Yan Ding2, Mary E. Choi2, Augustine M. K. Choi1, Stefan W. Ryter1 1Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, 2Department of Medicine, Renal Division, Brigham and Women's Hospital, Harvard Medical School, 3First Department of Critical Care Medicine and Pulmonary Services, University of Athens Medical School, Evangelismos Hospital, Athens, Greece JoVE 51066 Immunology and Infection Isolatie van Mouse Respiratory epitheelcellen en Blootstelling aan Experimentele Cigarette Smoke bij Air Liquid Interface Hilaire C. Lam1,2, Augustine M.K. Choi1, Stefan W. Ryter1 1Department of Medicine, Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, 2Cellular and Molecular Pathology, School of Medicine, University of Pittsburgh JoVE 2513 Medicine
Cecal ligatie en punctie-geïnduceerde Sepsis als een model om Autophagy studie bij muizen Ilias I. Siempos1,3, Hilaire C. Lam1, Yan Ding2, Mary E. Choi2, Augustine M. K. Choi1, Stefan W. Ryter1 1Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, 2Department of Medicine, Renal Division, Brigham and Women's Hospital, Harvard Medical School, 3First Department of Critical Care Medicine and Pulmonary Services, University of Athens Medical School, Evangelismos Hospital, Athens, Greece JoVE 51066 Immunology and Infection
Isolatie van Mouse Respiratory epitheelcellen en Blootstelling aan Experimentele Cigarette Smoke bij Air Liquid Interface Hilaire C. Lam1,2, Augustine M.K. Choi1, Stefan W. Ryter1 1Department of Medicine, Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, 2Cellular and Molecular Pathology, School of Medicine, University of Pittsburgh JoVE 2513 Medicine